ZHOU Shufeng, XIAO Zhe, ZHU Huan, ZHOU Huimin, YANG Mei, PENG Yong, LIU Xiaoli, HU Qinghua.. Effect of 12-week aerobic exercise on microcirculation function of sedentary college students[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(9): 1332-1335,1339. doi: 10.16835/j.cnki.1000-9817.2021.09.013
Citation: ZHOU Shufeng, XIAO Zhe, ZHU Huan, ZHOU Huimin, YANG Mei, PENG Yong, LIU Xiaoli, HU Qinghua.. Effect of 12-week aerobic exercise on microcirculation function of sedentary college students[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(9): 1332-1335,1339. doi: 10.16835/j.cnki.1000-9817.2021.09.013

Effect of 12-week aerobic exercise on microcirculation function of sedentary college students

doi: 10.16835/j.cnki.1000-9817.2021.09.013
  • Received Date: 2021-04-12
  • Rev Recd Date: 2021-06-22
  • Available Online: 2021-09-24
  • Publish Date: 2021-09-24
  •   Objective  To investigate the effects of different doses of aerobic exercise on the microvascular function of habitually sedentary college students.  Methods  A total of 69 students from Hubei Minzu University were recruited and divided into sports group A, sports group B and control group, with 23 students in each group (12 boys and 11 girls). The exercise group received 12 weeks of aerobic exercise intervention, in which group A exercised 1-2 times a week, group B exercised≥3 times a week, and the control group did not carry out any systematic sports. Microvascular response, Transcutaneous partial pressure of oxygen(TcpO2), Nitric oxide, Nitric oxide synthase (NOS) and En-dothelin-1 (ET-1) were measured before and after the test.  Results  After the test, the microvascular reactivity showed group and time interaction(P<0.01), in which exercise group B was greater than that of control group and exercise group A (P<0.01). There was no significant difference between exercise group A and control group (P>0.05), but the percutaneous partial pressure of oxygen (P=0.53) had no time interaction with other groups; NO(F=6.32) and NOS(F=7.91) had group and time interaction, in which exercise group B was greater than control group and exercise group A (P<0.01), and there was no significant difference between exercise group A and control group (P>0.05).   Conclusion  There is a "dose-effect" relationship between aerobic exercise and microcirculatory blood perfusion and endogenous NO. Continuous aerobic exercise ≥3 times a week for 12 weeks improved microcirculatory blood perfusion and promoted endogenous NO production in sedentary college students, but doing aerobic exercise for 1-2 times a week had no significant effect on microcirculatory blood perfusion and endogenous NO.
  • [1]
    JUSTIN D, GABRIE L F, YAN H M, et al. Microvascular endothelial dysfunction in sedenary, obese humans is mediated by NADPH oxidase influence of exercise training[J]. Arter Thr Vasc Biol, 2016, 36(12): 2412-2420. doi: 10.1161/ATVBAHA.116.308339
    [2]
    韩冬柏, 刘晓宇, 李娜, 等. 微循环障碍与高血压关系的研究进展[J]. 实用心脑肺血管病杂志, 2020, 28(5): 112-115, 120. doi: 10.3969/j.issn.1008-5971.2020.05.022

    HAN D B, LIU X Y, LI N, et al. Research progress on the relationship between microcirculatory disorders and hypertension[J]. Pract J Cardiac Cerebr Pneum Vascul Dis, 2020, 28(5): 112-115, 120. doi: 10.3969/j.issn.1008-5971.2020.05.022
    [3]
    OKADA H, TANAKA M, YASUDA T, et al. Decreased microcirculatory function measured by perfusion index is a novel indicator of diabetic kidney disease in patients with t-ype 2 diabetes[J]. J Diab Invest, 2020, 11(3): 681-687. doi: 10.1111/jdi.13193
    [4]
    HODGES G J, SHARP L, STEPHENSION C, et al. The effect of 48 weeks of aerobic exercise training on cutaneous vasodilator function in post-menopausal females[J]. Eur J Appl Physiol, 2010, 108(6): 1259-1267. doi: 10.1007/s00421-009-1330-0
    [5]
    TEW G A, GEORGE K P, CAB N T, et al. Endurance exercise training enhances cutane-ous microvascular reactivity in post-menopausal women[J]. Micr Res, 2011, 83(2): 223-228.
    [6]
    朱欢, 胡庆华, 彭爱萍, 等. 长期太极拳运动对中老年人膝关节皮肤微血管反应性、经皮氧分压的影响[J]. 中国应用生理学杂志, 2020, 36(4): 321-323, 384.

    ZHU H, HU Q H, PENG A P, et al. Effects of long-term Taijiquan exercise on skin microvascular reactivity and transcutaneous oxygen partial pressure of knee joint in middle-aged and elderly people[J]. Chin J Appl Physiol, 2020, 36(4): 321-323, 384.
    [7]
    朱欢, 高炳宏. 有氧运动对人体微血管反应性的作用及机制研究进展[J]. 生命科学, 2020, 32(8): 97-105.

    ZHU H, GAO B H. Research progress in effects and mechanisms of aerobic exercise on human microvascular reactivity[J]. Chin Bull Life Sci, 2020, 32(8): 97-105.
    [8]
    张丽萍, 章岚. 递增负荷运动方案推算超重/肥胖青年男性FATmax有效性研究[J]. 中国体育科技, 2018, 54(3): 87-91, 145.

    ZHANG L P, ZHANG L. Study on fatmax of overweight and obese young men by incremental load Exercise[J]. Chin Sports Tech, 2018, 54(3): 87-91, 145.
    [9]
    朱欢, 高炳宏. 微血管反应性在耐力性运动员训练中的应用[J]. 中国运动医学杂志, 2019, 38(10): 907-914 doi: 10.3969/j.issn.1000-6710.2019.10.013

    ZHU H, GAO B H. Application of microvascular reactivity in training of endurance athletes[J]. Chin J Sports Med, 2019, 38(10): 907-914 doi: 10.3969/j.issn.1000-6710.2019.10.013
    [10]
    朱欢, 高炳宏. 不同性别赛艇运动员肱二头肌微循环血流灌注量的比较[J]. 中国应用生理学杂志, 2016, 32(3): 277-278, 288.

    ZHU H, GAO B H. Comparison of microcirculation blood flow perfusion of biceps brachii in rowers of different genders[J]. Chin J App Physiol, 2016, 32(3): 277-278, 288.
    [11]
    MICHAEL M, 任倩(译). 每日久坐导致2型糖尿病风险升高22%[J]. 中华全科医师杂志, 2016, 15(12): 957.

    MICHAEL M, REN Q. The risk of type 2 diabetes mellitus increased by 22% due to daily sedentary time[J]. Chin J Gen Pract, 2017, 23(2): 957.
    [12]
    NAYLOR L H, DAVIS E A, KALIC R J, et al. Exercise training improvesvascular function in adolescents with type 2 diabetes[J]. Phys Rep, 2016, 4(4): e12713-e12724. doi: 10.14814/phy2.12713
    [13]
    PASQUALINI L, SCHILLACI G, INNOCENTE S, et al. Lifestyle intervention improves micov-as cular reactivity and increases serum adiponectin in overweight hypertensive patients[J]. Nutr Metab Cardiovas, 2010, 20(2): 87-92. doi: 10.1016/j.numecd.2009.03.002
    [14]
    MORAES R D, BAVEL D V, BRITO M D, et al. Effects of non-supervised low intensity aerobic excise training on themicrovascular endothelial function ofpatients with type 1 diabetes: anonpharacological interventional study[J]. BMC Card Dis, 2016, 16(23): 23-31.
    [15]
    BORGES J P, NASCIMENT A R, LOPES G O, et al. The impact of exercise frequency upon microvascular endothelium function and oxidative stress among patients with coronary artery disease[J]. Clin Physiol Funct Imag, 2018, 38(5): 840-846. doi: 10.1111/cpf.12492
    [16]
    MACHADO M V, VIEIRA A B, DA CONCEIÇÃO F, et al. Exercise training dose differentially alters muscle and heart capillary density and metabolic functions in an obese rat with metabolic syndrome[J]. Exp Physiol, 2017, 102(12): 1716-1728. doi: 10.1113/EP086416
    [17]
    PANISSA VALÉRIA L G, FUKUDA D H, CALDEIRA R S, et al. Is oxygen uptake measurement enough to estimate energy expenditure during high-intensity intermittent exercise? Quantification of anaerobic contribution by different methods[J]. Fron Phys, 2018, 9: 868-875.
    [18]
    LI M, WANG N, ZHANG J. MicroRNA-29a-3 pattenuates ET-1-induced hypertrophic responses in H9c2 cardiomyocytes[J]. Gene, 2016, 585(1): 44-50. doi: 10.1016/j.gene.2016.03.015
    [19]
    CORREIA-COSTA L, MORATO M, SOUSA T, et al. Urinary fibrogenic cytokines ET-1 and TGF-β1 are associated with urinary angiotensinogen levels in obese children[J]. Pediatr Nephrol, 2016, 31(3): 455-464. doi: 10.1007/s00467-015-3232-1
    [20]
    刘蜜, 李玉珍, 宋丹丹, 等. 不同性别和年龄健康成年人足趾皮肤温度和血流灌注量的测定分析[J]. 微循环学杂志, 2012, 22(4): 39-41.

    LIU M, LI Y Z, SONG D D, et al. Measurement and analysis of toe skin temperature and blood flow perfusion in healthy adults of different gender and age[J]. Chin J Microcircul, 2012, 22(4): 39-41.
    [21]
    王艺璇, 蔡军. 剪切力和拉伸应力对血管内皮细胞的影响[J]. 中国医学前沿杂志(电子版), 2012, 4(8): 38-41. doi: 10.3969/j.issn.1674-7372.2012.08.009

    WANG Y Y, CAI J. Effects of shear stress and tensile stress on vascular endothelial cells[J]. Chin J Front Med Sci(Electron Ver), 2012, 4(8): 38-41. doi: 10.3969/j.issn.1674-7372.2012.08.009
    [22]
    DOW C A, STAUFFER B L, BRUNJES D L. Regular aerobic exercise reduces endothelin 1 mediated vasoconstrictor tone in overweight and obese adults[J]. Exper Phys, 2017, 102(9): 1133-1142. doi: 10.1113/EP086454
    [23]
    罗琪. 有氧运动对大鼠血脂及血管内皮素和一氧化氮合酶的影响[D]. 苏州: 苏州大学, 2006.

    LUO Q. Effects of aerobic exercise on blood lipid, endothelin and nitric oxide synthase in rats[D]. Suzhou: Soochow University, 2006.
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