Investigation on an outbreak of human metapneumovirus respiratory tract infection in a primary school of Huzhou City

LIU Binhui; PENG Erlei, PENG; PENG Caiwei

doi:10.16835/j.cnki.1000-9817.2022.01.027

Volume 43 Issue 1

Jan. 2022

Turn off MathJax

Article Contents

Article Navigation > CHINESE JOURNAL OF SCHOOL HEALTH > 2022 > 43(1): 120-122, 128

LIU Binhui, PENG Erlei, PENG, PENG Caiwei. Investigation on an outbreak of human metapneumovirus respiratory tract infection in a primary school of Huzhou City[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2022, 43(1): 120-122, 128. doi: 10.16835/j.cnki.1000-9817.2022.01.027

Citation:

LIU Binhui, PENG Erlei, PENG, PENG Caiwei. Investigation on an outbreak of human metapneumovirus respiratory tract infection in a primary school of Huzhou City[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2022, 43(1): 120-122, 128. doi: 10.16835/j.cnki.1000-9817.2022.01.027

Citation:

PDF( 432 KB)

Investigation on an outbreak of human metapneumovirus respiratory tract infection in a primary school of Huzhou City

doi: 10.16835/j.cnki.1000-9817.2022.01.027

Department of Infectious Disease Control and Prevention, Huzhou Nanxun Center for Disease Control and Prevention, Huzhou (313009), Zhejiang Province, China

Received Date: 2021-08-08
Rev Recd Date: 2021-09-18
Publish Date: 2022-01-25

Abstract

Abstract

Objective To understand the epidemiological characteristics of an outbreak of respiratory tract infection caused by human metapneumovirus (hMPV) in a primary school in Huzhou City, and to provide scientific reference for the prevention and control of the outbreak of upper respiratory tract infection caused by hMPV in the future. Methods The investigation was carried out according to the Guidelines for Handling Influenza Like Case Outbreaks (2018 version). The throat swabs were collected to carry out COVID-19 nucleic acid test. If negative, influenza virus and other common 14 upper respiratory tract virus detection would be conducted. Results A total of 53 cases of human metapneumovirus infection were found, the first case was found on December 15, 2020; the cases concentrated from December 21 to December 26; the last case was on December 29. It lasted 15 days and the epidemic ended. All the cases were first-year students, and the incidence rate of the affected classes was 44.92% (53/118), among which the incidence rate of 101 classes was 23.08% (9/39), 102 classes was 53.85% (21/39), 103 classes was 57.50%(23/40), the difference was statistically significant(χ²=10.07, P < 0.05). The age of the patients ranged from 6 to 7 years. The morbidity rate of boys was 48.00%(24/50) and that of girls was 42.65% (29/68), with no significant difference(χ²=0.33, P>0.05). The clinical symptoms of all cases were mild, mainly cough, sore throat, runny nose, only a small number of fever. Throat swabs of 20 patients were collected, and 13 cases were positive for human metapneumovirus nucleic acid. Conclusion The symptoms caused by human metapneumovirus are relatively mild, which is not easy to attract the attention of schools and parents. Schools should carry out relevant prevention and control knowledge publicity, do a good job in the morning and afternoon inspection, and put an end to classes with diseases.
- Respiratory tract infections,
- Disease outbreaks,
- Prevalence,
- Students

FullText(HTML)

References(14)

References

[1]	VAN DEN HOOGEN B G, DE JONG J C, et al. A newlydiscovered human pneumovirus isolated from young children withrespiratory tract disease[J]. Nat Med, 2001, 7(6): 719-724. doi: 10.1038/89098
[2]	赵颖. 人偏肺病毒感染的研究进展[J]. 宁夏医学杂志, 2013, 35(7): 658-660. https://www.cnki.com.cn/Article/CJFDTOTAL-NXYX201307048.htm ZHAO Y. Research progress of human metapneumovirus infection[J]. Ningxia Med J, 2013, 35(7): 658-660. https://www.cnki.com.cn/Article/CJFDTOTAL-NXYX201307048.htm
[3]	娜仁, 张嘉懿, 司萍, 等. 人hMPV最新研究进展[J]. 中国城乡企业卫生, 2019, 2(2): 30-32. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCXW201902013.htm NA R, ZHANG J Y, SI P, et al. The latest research progress of human hMPV[J]. Urban Rural Enterp China, 2019, 2(2): 30-32. https://www.cnki.com.cn/Article/CJFDTOTAL-ZCXW201902013.htm
[4]	HASVOLD J, SJODING POHL M, POHL K, et al. The role of human metapneumovirus in the critically ill adult patient[J]. J Crit Care, 2016, 31(1): 233-237. doi: 10.1016/j.jcrc.2015.09.035
[5]	张琴, 杨锡强, 赵耀, 等. 重庆地区0~6岁儿童人类偏肺病毒感染状况调查[J]. 中国实用儿科杂志, 2007, 22(8): 579-582. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSEK200708006.htm ZHANG Q, YANG X Q, ZHAO Y, et al. Investigation of human metapneumovirus infection in children aged 0-6 years old in Chongqing area[J]. Chin J Practic Pediatr, 2007, 22(8): 579-582. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSEK200708006.htm
[6]	伍严安, 苏跃青, 黄毅, 等. 福州地区儿童急性呼吸道人类偏肺病毒感染[J]. 福建医科大学学报, 2007, 41(5): 433-436. https://www.cnki.com.cn/Article/CJFDTOTAL-FJYD200705015.htm WU Y A, SU Y Q, HUANG Y, et al. Acute respiratory tract infection of human metapneumovirus in children in Fuzhou area[J]. J Fujian Med Univ, 2007, 41(5): 433-436. https://www.cnki.com.cn/Article/CJFDTOTAL-FJYD200705015.htm
[7]	刘爱玲, 刘淑燕, 刘军, 等. 深圳地区急性上吸呼道感染住院患儿人偏肺病毒感染现状及基因分析[J]. 临床输血与检验, 2018, 20(2): 150-153. https://www.cnki.com.cn/Article/CJFDTOTAL-LSXY201802015.htm LIU A L, LIU S Y, LIU J, et al. Human metapneumovirus infection and gene analysis in hospitalized children with acute upper respiratory tract infection in Shenzhen area[J]. Clin Blood Transf Test, 2018, 20(2): 150-153. https://www.cnki.com.cn/Article/CJFDTOTAL-LSXY201802015.htm
[8]	蔡伟, 李洋, 刘锋. 一起人类偏肺病毒感染疫情调查分析[J]. 中国妇幼卫生杂志, 2020, 11(3): 74-76. https://www.cnki.com.cn/Article/CJFDTOTAL-YZWS202003015.htm CAI W, LI Y, LIU F. Investigation and analysis of an epidemic of human metapneumovirus infection[J]. Chin J Matern Child Health, 2020, 11(3): 74-76. https://www.cnki.com.cn/Article/CJFDTOTAL-YZWS202003015.htm
[9]	肖新才, 吴莉萍, 魏凌云, 等. 一起人偏肺病毒感染导致的急性呼吸道感染暴发疫情调查[J]. 中华流行病学杂志, 2013, 34(9): 943-944. XIAO X C, WU L P, WEI L Y, et al. Investigation on an outbreak of acute respiratory tract infection caused by human metapneumovirus infection[J]. Chin J Epidemiol, 2013, 34(9): 943-944.
[10]	陈其娴, 罗经伟, 许少坚, 等. 1起人偏肺病毒引起的急性呼吸道感染暴发疫情调查[J]. 热带医学杂志, 2020, 20(2): 257-260. https://www.cnki.com.cn/Article/CJFDTOTAL-RDYZ202002028.htm CHEN Q X, LUO J W, XU S J, et al. Investigation on an outbreak of acute respiratory tract infection caused by human metapneumovirus[J]. J Tropic Med, 2020, 20(2): 257-260. https://www.cnki.com.cn/Article/CJFDTOTAL-RDYZ202002028.htm
[11]	汤云霞, 杨思园, 于凤婷, 等. 人类偏肺病毒感染研究进展[J]. 国际病毒学杂志, 2018, 25(2): 132-136. https://www.cnki.com.cn/Article/CJFDTOTAL-GEKX200501012.htm TANG Y X, YANG S Y, YU F T, et al. Research progress of human metapneumovirus infection[J]. Inter J Virol, 2018, 25(2): 132-136. https://www.cnki.com.cn/Article/CJFDTOTAL-GEKX200501012.htm
[12]	刘丽珍, 陈宏标, 梁静. 一起校园人偏肺病毒感染暴发疫情的流行病学调查与危险因素研究[J]. 医学动物防制, 2021, 37(3): 265-268. https://www.cnki.com.cn/Article/CJFDTOTAL-YXDZ202103015.htm LIU L Z, CHEN H B, LIANG J. Epidemiological investigation and risk factors of an outbreak of human metapneumovirus infection on campus[J]. Prevent Control Med Animals, 2021, 37(3): 265-268. https://www.cnki.com.cn/Article/CJFDTOTAL-YXDZ202103015.htm
[13]	国家卫生健康委. 关于印发流感样病例暴发疫情处置指南(2018年版)的通知[Z]. 2018-11-14. National Health Commission of the PRC. Notice on the issuance of guidclines for the handling of outbreaks of influenza-like cases[Z]. 2018-11-14.
[14]	毛琦, 王瑞平, 郭晓芹, 等. 上海市松江区2016年传染病类公共卫生苗子事件分析[J]. 上海预防医学, 2019, 31(2): 141-145. https://www.cnki.com.cn/Article/CJFDTOTAL-SHYI201902014.htm MAO Q, WANG R P, GUO X Q, et al. Analysis of public health seedling incident of infectious diseases in Songjiang District of Shanghai in 2016[J]. Shanghai Prevent Med, 2019, 31(2): 141-145. https://www.cnki.com.cn/Article/CJFDTOTAL-SHYI201902014.htm