2019 Vol. 40, No. 4

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2019, 40(4)
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2019, 40(4): 481-482. doi: 10.16835/j.cnki.1000-9817.2019.04.001
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An overview on the importance of metabolomics study in early screening and diagnosis of autism spectrum disorders
WU Lijie
2019, 40(4): 483-485,489. doi: 10.16835/j.cnki.1000-9817.2019.04.002
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Autism spectrum disorder (ASD) is the fast growing neurodevelopmental disorder worldwide. No biomarker tests for ASD currently exist. Research efforts in metabolomic may shed light on potential biomarkers for ASD. Here, we will review the current progress in metabolomics in early screening and diagnosis of ASD and focus on its effectiveness and caveats in clinical practices. This editorial also includes thoughtful discussion of future directions to provide better guidance for research in this area.
Dilemma of psychological crisis intervention and coping strategies among college students
LI Yonghui
2019, 40(4): 486-489. doi: 10.16835/j.cnki.1000-9817.2019.04.003
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During the past few years, mental health crisis of college students has occurred frequently which significantly increased the expectations and requirements of mental health education and counseling in colleges and universities. After the promulgation and implementation of the National Mental Health Law, higher requirements have been put forward for the mental health education of college students, especially for the intervention of college students' psychological crisis. It makes fundamental work in college mental health education and counselling more difficult and confusing in terms of the definition of mental health problems diagnosis and treatment, the appropriate place and context of mental health counseling, school management and the balance of students' rights and interests. The consulting qualification of consultants in colleges and universities is facing difficulties and challenges. This paper expounds the function and influence of "Mental Health Law" on college students' psychological crisis intervention, and defines the boundary between psychological consultation and psychotherapy. This paper proposes establishment of an effective psychological crisis intervention system, including clarification in the responsibility of mental health education in colleges and universities, implementation the combination of medicine and education, perfecting the rules and regulations of mental health education in colleges and universities, and improvement in the ability to deal with psychological crisis, which sheds lights on mental health education system for college students.
Case-control study of vitamin B12 and metabolite MMA and transporter TCN2 in children with ASD
ZOU Mingyang, LI Ling, LI Dexin, MA Yongjuan, SUN Caihong, WU Lijie
2019, 40(4): 490-492,495. doi: 10.16835/j.cnki.1000-9817.2019.04.004
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Objective To investigate the level of vitamin B12 in children with autism spectrum disorder (ASD), and provide a theoretical basis for early detection and drug treatment of ASD. Methods A total of 89 ASD cases and 89 matched controls were collected. The levels of urinary methylmalonic acid (MMA) and serum vitamin B12, Transcobalamin Ⅱ (TCN2) were determined by enzyme-linked immunosorbent assay (ELISA). TCN2 gene rs1801198 was genotyped by SNaPshot. Results The serum levels of vitamin B12 and TCN2 in children with ASD [ (369.08±131.88) pmol/L, (1.56±0.16) ng/mL] were significantly lower than those in the control group[ (485.16±200.33) pmol/L, (1.71±0.17) ng/mL] (t=-5.47,-5.92, P<0.05). The level of MMA in urine of ASD children [ (758.97±106.96) ng/mL] was significantly higher than that in the control group[ (693.66±121.72) ng/mL] (t=3.94, P<0.05); The genetic polymorphism of rs1801198 locus was not associated with the risk of ASD (P>0.05), and there was no significant correlation with serum TCN2 level (F=1.16, P>0.05). Conclusion ASD children are at a potential deficiency of vitamin B12 and should strengthen their nutritional interventions while conducting ASD interventions.
Case-control study on temperament characteristics of children with autism spectrum disorders aged 3-7 years old in Harbin
PANG Xiuming, XU Meng, MA Yongjuan, ZOU Mingyang, LI Ling, LI Dexin, SUN Caihong
2019, 40(4): 493-495. doi: 10.16835/j.cnki.1000-9817.2019.04.005
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Objective To explore the differences of temperament characteristics between children with autism spectrum disorder (ASD) and normal children, and to provide evidence for early detection of ASD children and the development of personalized treatment plans. Methods In this case-control study, we enrolled 129 ASD children and 129 normal children aged 3-7 years. The Behavioral Style Questionnaire (BSQ) scale was used to assess the temperament. Results ASD children got higher scores in terms of "activity level", "withdrawal", "adaptability", "emotional nature", "persistence", and "response threshold" temperament dimensionality scores (P<0.05), and lower scores in terms of "rhythmical", "response intensity" temperament dimensionality scores than normal children (P<0.05). However, there was no significant difference in "attention dispersiveness" between ASD group and control group (P>0.05). Among the children in the ASD and control group, the proportion of each temperament type was "easy to raise temperament type" (41.8% vs 62.8%), "partially easy to raise temperament type" (31.8% vs 27.9%), "partially difficult to raise temperament type" (17.1% vs 6.2%), "slow-up-to-warm temperament type" (7.7% vs 2.3%) and "difficult to raise temperament type" (1.6% vs 0.8%).Statistical analysis showed that the rate of "easy to raise temperament type" was lower than that in normal children (P<0.05), while the rates of "partially easy to raise temperament type", "partially difficult to raise temperament type", "difficult to raise temperament type", and "slow-up-to-warm temperament type" in ASD children were higher (P<0.05). Conclusion There was significant difference in temperament characteristics between ASD children and normal children. The evaluation of temperament type contributes to early detection of ASD children and provides a reference for their behavioral correction.
Study on the characteristics of auditory in children with autism spectrum disorders
PANG Xiuming, WANG Xiaomin, CHEN Qi, LIU Xiaocui, SUN Caihong, WANG Jia
2019, 40(4): 496-498,502. doi: 10.16835/j.cnki.1000-9817.2019.04.006
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Objective To explore the characteristics of Auditory Brainstem Response (ABR) in children with ASD, and analyze their relation with the core symptoms of ASD. Methods Ninty children aged 2-6 with ASD were recruited from Harbin in this study. The data of ABR was collected by using BAEP, and the association among children's absolute latency and interpeak latency of ABR, core symptoms of ASD children's behavior and clinical manifestation was analyzed. Results Compared with the normal average value, children with ASD had longer the absolute latency of wave Ⅰ, Ⅲ, Ⅴ in bilateral ears, which were (1.51±0.20) (3.83±0.34) (5.63±0.23) ms, (1.54±0.16) (3.78±0.23) (5.63±0.22) ms, respectively (P<0.05). Some children's interpeak latency of Ⅰ-Ⅲ, Ⅲ-Ⅴ, Ⅰ-Ⅴ were longer than normal values. Children younger than 3 years old showed prolonged peak intervals of Ⅰ-Ⅲ and Ⅰ-Ⅴ than children in 3-7 years old. The study has also showed that there was positive correlation between the absolute latency of waveⅠin left ear and the social function defect (r=0.45, P<0.05); there was positive correlation between the latency of wave Ⅴin right ear or the latency of waveⅠin left ear or the Ⅰ-Ⅲ peakinterval and non-verbal communication ability dysfunction (r=0.35, 0.39, 0.34, P<0.05); there was positive correlation between the Ⅰ-Ⅲ peak interval and the repeated stereotyped symptoms (r=0.39, 0.35, P<0.05). Conclusion Children with ASD have abnormal auditory behavior. The absolute latency and interpeak latency of ABR is correlated to some parts of core symptoms of ASD.
Association between neuroimmunological indicators and autism spectrum disorders
WANG Lin, YANG Xiaolei, MA Yongjuan, LIU Xiaocui, ZOU Mingyang, SUN Caihong, WU Lijie
2019, 40(4): 499-502. doi: 10.16835/j.cnki.1000-9817.2019.04.007
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Objective To explore the relationship among osteopontin (OPN), Interleukin-17 A (IL-17 A), anti-MBP auto-antibody and autism spectrum disorder (ASD), and to provide the theoretical basis for the etiology and pathogenesis of ASD. Methods Forty autistic children and forty matched healthy children were enrolled in this case-control study. The levels of OPN, IL-17 A, anti-MBP auto-antibody in serum were measured by enzyme-linked immunosorbent assay (ELISA). The associations between those metabolic levels and the severity and intelligence of ASD children were performed by Pearson or Spearman correlation. Results Children with ASD had higher serum levels of OPN, IL-17 A [ (296.89±162.95), 0.93] pg/mL compared to healthy control[ (217.98±113.39), 0.62] pg/mL (P<0.05). Serum OPN, IL-17 A, and anti-MBP auto-antibody levels in ASD group were not correlated with the scores of ABC, CARS, and PPVT (P>0.05). However, anti-MBP auto-antibodies level in children with ASD were positively correlated with OPN and IL-17 A levels, respectively (r=0.35, 0.34, P<0.05). Conclusion It was obvious that the ASD children were found with neuroimmunologic abnormality, and the underlying mechanism needs to be further explored.
Doctor visit, rehabilitation and foster care of children with autism spectrum disorders in Heilongjiang Province
LIU Xiao-cui, WANG Jia, SUN Caihong, ZOU Mingyang, MA Yongjuan, WANG Lin, WU Lijie
2019, 40(4): 503-506,510. doi: 10.16835/j.cnki.1000-9817.2019.04.008
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Objective To understand the status of doctor visit, rehabilitation and foster care of children with autism spectrum disorders in Heilongjiang Province, and to provide a scientific reference for improving ASD rehabitation education system and making the related policies. Methods Eight autism rehabilitation institutions were selected in Heilongjiang Province by stratified cluster sampling, 357 primary caregivers of ASD children participated in the survey by using the questionnaire "ASD Children's Rehabilitation Education Status and Needs". Results The average age of abnormal behavior found of ASD children was (31.08±12.96) months, and the average age of first doctor visit was (35.88±13.20) months, the average age of diagnose was (38.64±13.20) months, and initial rehabilitation was (43.56±16.08) months. The proportion of children who had been diagnosed and have trained in the rehabilitation institutions before the age of 3 years was only 39.0% and 32.0%, respectively. The proportion of rehabilitation out of home town was 47.3%, and rehabilitation>20 hours per week was 73.4%. The proportion of fathers' and mothers' work lives affected was 34.5% and 67.8%, respectively, the differences were of statistical signficance (χ2=226.32, P<0.01). About 41.2% of ASD families received government financial support. Conclusion The average age of diagnose is late prolonged, and the proportion of children diagnosed and training before the age of 3 years was relatively low. There were obvious regional differences of rehabilitation education resources distributions of ASD in Heilongjiang Province. The results also demonstrate the need to sustain and enhance the coverage rate of the government financial support.
Association between basic fibroblast growth factor and autism spectrum disorders
YANG Xiaolei, ZOU Mingyang, WANG Lin, MA Yongjuan, HAN Panpan, WU Lijie
2019, 40(4): 507-510. doi: 10.16835/j.cnki.1000-9817.2019.04.009
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Objective To investigate the level of human blood basic fibroblast growth factor (FGF2) among children with autism spectrum disorder (ASD) and its correlation with behavioral phenotypes, to provide a reference for etiological research of ASD. Methods ASD Children were selected to get rehabitation training in reseach center of children development behavior in Harbin Medical University and the rehabitation constitution for ASD disabilities in Heilongjiang, 40 children were induded as ASD group, 41 healthy children in Harbin kindergarten was classified as control group. The Autism Behavior Checklist (ABC), Childhood Autism Rating Scale (CARS) and Peabody Picture Vocabulary Test (PPVT) were used to assess the severity and intelligence of ASD children, respectively. Results No difference was found in FGF2 level between ASD children (4.95 pg/mL) and normal children (8.51 pg/mL) (P>0.05). However, difference in FGF2 level between the two groups were found in 4-year-old group (P<0.05). The level of FGF2 differed across different severity and intelligence of ASD children (P<0.05). Conclusion Abnormal levels of FGF2 in ASD children may correlate with severity of autistic traits and intelligence of children.
Height changes among students under the National Nutrition Improvement Program for Rural Compulsory Education Students during 2012-2017
CAO Wei, XU Juan, LI Li, GAN Qian, YANG Titi, XU Peipei, PAN Hui, HU Xiaoqi, ZHANG Qian
2019, 40(4): 511-514. doi: 10.16835/j.cnki.1000-9817.2019.04.010
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Objective To analyze the height changes among children who had received subsidies of the National Nutrition Improvement Program for Rural Compulsory Education Students (NNIPRCES) by comparing data from the year of 2012 and 2017. Methods Among 699 counties where NNIPRCES was implemented, at least 10% of elementary schools and primary middle schools with different food supply modes (school canteen meals, company meals, and mix meals) in the county were selected randomly. Forty students from one or two classes from each grade (grade 1 to grade 9) were randomly selected, to ensure equal proportion of boys and girls in each grade were surveyed, data on height from 1 655 793 students measured in 2012 were compared with 1 419 281 students measured in 2017. Height was measured by metal height pole within 0.1 cm accuracy. Results From 2012 to 2017, the average increase of height in boys and girls aged 6-15 years was 1.9 and 2.0 cm, respectively. Among them, maximum increment was found in boys at the age of 13 years and in girls at the age of 12 years, respectively, which was 3.0 and 2.8 cm. The average increase in boys from the central and western region was 2.1 and 2.2 cm, respectively, while increase in girls from the central and western region was both 2.2 cm. Compared with the results from 2012, height of boys with the 5 th, 50 th and 95 th height percentiles in 2012 increased by 1.7, 2.0 and 2.1 cm, respectively in 2017, while the increase in girls was 2.1, 2.0 and 2.2 cm, respectively. The average increment of western students with the 5 th and 95 th height percentiles was higher than those of students from the central region. Conclusion The average height of students has increased after the implementation of NNIPRCES. However, the development was unbalanced between the central and western region, which requires more targeted intervening strategies to improve the nutritional status of students.
Sexual knowledge, attitude and associated factors among primary and middle school students
NIE Huimin, YU Xiaoming, TAN Xueqing, WANG Yuqing, SHI Yanqin, ZHANG Tinghao, SONG Yuzhen, CAO Xingyuan, XIA Mingjuan, YAN Shaohui, LI Xiaodong, TANG Jia, PENG Weihong
2019, 40(4): 515-518,522. doi: 10.16835/j.cnki.1000-9817.2019.04.011
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Objective To understand the awareness of sexual knowledge among primary and secondary school students, as well as their attitudes towards school sex education and to provide a reference for school-based sex education. Methods A total of 5 531 primary and secondary school students were selected from Beijing, Chongqing, Heilongjiang (Harbin and Jiamusi) and Hubei (Wuhan and Xiaogan) by stratified cluster sampling and were investigated with self-reported questionnaire. Results Sex-related knowledge scored 62.33±19.35, with a pass rate of 61.9%, and the excellent rate 17.5%. Sexual knowledge of junior high school students scored 64.30±19.07, with the pass rate of 64.7%, and the excellent rate 22.0%. A large proportion of primary students reported unaware of pubertal growth and HIV/AIDS-related knowledge, and a large proportion of junior high students unaware of reproductive physiology. Multivariate Logistic regression analysis showed region, grade, gender, and suburban areas were related to the level of sexual knowledge (P<0.05). More than 76.0% primary students and 85.9% middle school students agreed on the importance of school sexuality education. 59.7% of primary school students and 73.3% of junior high school students hoped to include school sexuality education in compulsory education courses; 59.8% of primary school students and 68.3% of junior high school students felt that school sexuality education should be equipped with specialized teachers. Conclusion Chinese primary and secondary school students are lack of sexual knowledge. As students have strong wills to get more information on sexual knowledge, schools should provide them with more comprehensive and effective sex education through appropriate courses and activities.
Analysis of energy drinks consumption and associated factors among college students
HU Chunmei, QI Mosha, XIAO Qianguo
2019, 40(4): 519-522. doi: 10.16835/j.cnki.1000-9817.2019.04.012
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Objective To investigate college students' energy drink (ED) consumption and associated factors, and to provide a reference for maintaining college students' mental and physical health. Methods Stratified cluster sampling was used to select 2 264 college students to complete questionnaires for the condition of energy drinking and associated influencing factors. Results Within a month, 51.0% college students had drunk ED, 46.8% students' drinking frequency was ≤9 times, 4.2% students' drinking frequency was ≥10 times; there were significant differences in different gender, major, grade, BMI, smoking, drinking, gambling and weight controlling behaviors students' ED consumption frequency (χ2 were 168.91, 149.08, 92.92, 25.20, 83.42, 85.77, 11.50, 20.50 respectively, both P<0.01), the males' (65.6%) was higher than the females' (38.2%), the sports majors' (74.1%) was higher than the arts', sciences' and painting majors' (45.6%, 44.6%, 42.2%), the freshmen and sophomores' (58.9%, 58.2%) were higher than the juniors' (37.4%), the normal and overweight-obesity BMIs' (53.5%, 54.4%) were higher than the too low BMIs' (40.5%), the smokers' (68.4%) was higher than the non-smokers' (45.7%), the drinkers' (63.5%) was higher than the non-drinkers' (43.4%), the gamblers' (62.1%) was higher than the non-gamblers' (49.8%), the dieters' (53.9%) was higher than the non-dieters' (43.2%); the gender, major, grade, smoking, drinking and weight controlling behaviors were associated factors on college students' energy drink consumption, males'consumption was more than female's (OR=3.13), freshmen and sophomores' consumption were more than juniors' (OR=2.40, 2.23), the students' consumption of sports majors was more than that of science and painting major (OR=0.28, 0.48), students with smoking, drinking and losing weight consumed more ED than students without these behaviors (OR=0.77, 0.80, 0.79). Conclusion More than half college students had drunk ED; society, school and home should pay attention to this phenomenon, and take measures to reduce ED consumption frequency, to maintain students' physical and mental health.
Application and effect evaluation of "3-PR" participatory health education model in the improvement of health literacy of secondary health school
RONG Honghui, XU Ning, JI Qiang, LU Lu, ZHANG Ling, PENG Yi, CHEN Ji' an, WU Shuxing
2019, 40(4): 523-526. doi: 10.16835/j.cnki.1000-9817.2019.04.013
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Objective To compare the effect of two different methods of "3-PR" participatory health education and traditional distribution of publicity materials on health literacy improvement of medical students, to provide a reference for making more effective measure to improve health literacy. Methods 173 Second-grade students in nursing major were selected in a secondary vocational school in Datong City. Two different intervention methods were used to intervene for 8 weeks. The experimental group (92 students) received "3-PR" participatory health education; the traditional health education intervention in the control group (81 students). The "National Residents' Health Literacy Monitoring Questionnaire 2015" was used to conduct a questionnaire survey on the experimental group and the control group before and after the intervention, and to compare the effects before and after the intervention. Results The average score of health literacy was (36.04±9.43) points and (36.01±10.17) points before and after intervention in the control group; (35.78±8.91) points and (49.53±13.53) points before and after intervention in the experimental group; No statistical difference between experimental and control group was found before intervention (t=0.18, P=0.86); There was no significant difference in health literacy score before and after intervention for the control group (t=0.03, P=0.98); Health literacy significantly increased in the experimental group after intervention (t=-11.36, P=0.00). Adequate health literacy accounted for 3.70% and 4.94% before and after intervention in the control group and 4.35% and 45.65% in the experimental group before and after intervention. No significant difference was found in adequate health literacy proportion between the two groups before intervention (χ2=0.00, P=1.00). However, the difference showed statistically significant after intervention (χ2=36.58, P=0.00). The change of health literacy score in the control group and the experimental group was (-0.02±7.52) and (12.75±10.77), respectively, accounting for 1.24% decrement and 41.30% increment. The difference between the two groups was statistically significant (t=-8.93, P=0.00). The dimension-and type-specific score of health literacy showed similar pattern. Conclusion The "3-PR" participatory health education model is more effective than the traditional health education method in improving health literacy, and it could be carried out by multi-disciplinary students.
Preliminary exploration and evaluation of POL intervention in young students at high-risk of AIDS
ZHANG Wenjing, WANG Yixin, WU Jing, HU Yifei, GAO Disi, CHEN Tianqi, CUI Wenxin, MA Yinghua
2019, 40(4): 527-530. doi: 10.16835/j.cnki.1000-9817.2019.04.014
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Objective Explore the feasibility of POL intervention based on life skills in young students at high-risk of AIDS, and to provide reference for POL intervention. Methods Nine potential POLs were recruited from young students at high risk of AIDS in Xi'an, and received life-skill-based interventions from May to October in 2017. A unified approach was adopted before the intervention. The effect of intervention was evaluated at 1 month and 3 months after the intervention. Results The difference in POLs peer status and psychosocial ability scores was not significant after the intervention. The scores of persistence efficacy dimension of condom use efficacy before, 1-month and 3-month after the intervention were (10.56±1.88) (11.11±2.21) (12.89±2.09) (F=6.84, P<0.05) respectively. No significant changes were found in AIDS-related knowledge and behavior before and after the intervention. POL has increased from 108 students before intervention to 216 publicity coverage after three months intervention, however, the difference was not statistically significant. Feasibility analysis of the POL intervention showed that 8 of the POLs considered to be "very useful". Conclusion Life skill-based POL intervention for young students at high-risk of AIDS has a wide coverage and reasonable acceptance, as well as condom use adherence. The long-term effectiveness still needs to be verified.
Association of overweight and obesity with exercise and school surrounding environment among primary school students in Lanzhou
GOU Qifeng, WANG Runping, BA Teer
2019, 40(4): 531-533. doi: 10.16835/j.cnki.1000-9817.2019.04.015
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Objective To analyze correlation between overweight and obesity among primary school students in Lanzhou with exercise and environmental factors around schools, and to provide a reference for reducing the overweigh and obesity rate of students. Methods Using cluster random sampling method, a total of 3 600 pupils from grade 4 to grade 6 in 8 primary schools in 4 districts of Lanzhou were investigated. Logistic regression model was used to analyze the relationship between overweight and obesity, exercise and environmental factors surrounding schools. Results The overweight rate was 13.8% (18.0% for boys and 9.5% for girls) and the obesity rate was 10.8% (11.7% for boys and 9.8% for girls), there was statistical significance in the differences of overweight rate between genders (χ2=55.10, P<0.01). There was no statistical significance in the differences of obesity rate between genders (χ2=3.39, P=0.07). The primary environmental factors causing overweight and obesity among boys included number of Internet cafes (OR=1.81), while for girls it was number of fast food restaurants (OR=2.39). Conclusion Too many Internet cafes and fast food restaurants surrounding school associates with higher risk of obesity among students. Public health interventions should be implemented targeting surrounding environment of schools, which might help reducing the occurrence of overweight and obesity in primary school students.
Study on the AIDS knowledge level and its influencing factors of middle school students in the high prevalence area of AIDS in Liangshan Yi autonomous prefecture
DONG Lingling, GUI Bing, YANG Hong, ZHANG Shize, WANG Renli
2019, 40(4): 534-537. doi: 10.16835/j.cnki.1000-9817.2019.04.016
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Objective To understand the awareness level of AIDS knowledge and its influencing factors among middle school students from AIDS high prevalence areas of Yi Autonomous Prefecture (Liangshan Prefecture), and to provide a reference for making propaganda strategies of AIDS knowledge and intervention measures in the relevant departments. Methods Totally 10 749 students in 4 middle schools were selected from AIDS high prevalence areas of Yi Autonomous Prefecture in Liangshan by the method of cluster sampling. A self-made questionnaire was used to investigate the ways of getting AIDS knowledge and the condition of conducting AIDS life training skills in school. Results The awareness rate of AIDS-related knowledge among middle school students in Liangshan Prefecture was 44.4%. According to the results of multivariate Logistic regression analysis, female students, junior grade, Yi nationality, poor self-evaluation, lack of parents, living in rural areas, good family economic condition (student self-assessment), living in a community of Yi nationality were all the dangerous factors to the awareness rate of AIDS. School education, radio and television, and health promotion were the main ways for students to acquire AIDS knowledge (88.82%, 80.83%, 73.54%). Minority students, students in severely affected areas received less AIDS life skills training in schools, the time was later, and student needs were not strong. Conclusion The AIDS awareness level of middle school students in Liangshan AIDS high-incidence area is too low, so it is necessary to pay attention to develop targeted programs to strengthen AIDS health education for middle school students.
Interaction effects of co-consumption of takeaway fast foods and sodas on depressive symptom in Chinese adolescents
XU Honglyu, WAN Yuhui, ZHANG Shichen, SUN Ying, XU Huiqiong, YANG Rong, WANG Wei, ZENG Hanjun, TAO Fangbiao
2019, 40(4): 538-541,545. doi: 10.16835/j.cnki.1000-9817.2019.04.017
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Objective To explore the association between co-consumption of takeaway fast foods and sodas with depressive symptoms among Chinese adolescents, and to provide a reference for reducing the occurence of depression among adolescents. Methods A multi-center population-based survey was conducted in 32 schools in 4 provinces across China. A total of 14 500 adolescents completed eligible questionnaires. Depressive symptoms were assessed by using Children's Depression Inventory (CDI), while consumption of takeaway fast foods and sodas was collected using the semi-quantitative Food Frequency Questionnaire (FFQ). Results 27.26% (3 952/14 500) of adolescents were reported of depressive symptoms. The low-, middle-, and high-frequency consumption of takeaway fast foods (aOR=1.12, 1.73, 1.56, P<0.05) and sodas (aOR=1.64, 2.17, 3.54, P<0.01) were associated with depressive symptoms, and dose-response relationships were observed in all association (P<0.01). Meanwhile, positive additive interactions were observed in the association (aOR=2.46, P<0.01). The relative excess risk, attribution ratio and the interaction index of synergy was 0.45 (0.12-0.77), 0.18 (0.06-0.30) and 1.44 (1.10-1.89), respectively. Conclusion Co-consumption of takeaway fast foods and sodas significantly associates with depressive symptoms by synergistic effect among Chinese adolescents.
Effectiveness of exercise intervention on sleep quality and negative emotion among female college students with anxiety
GONG Yujing, ZHANG Yifan, YANG Xinyi, GUAN Yuan, TANG Donghui
2019, 40(4): 542-545. doi: 10.16835/j.cnki.1000-9817.2019.04.018
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Objective To investigate the effect of exercise intervention on sleep quality of female college students with anxiety, and to further explore the mediating effect of negative emotions in this association. Methods Seventy female college students were randomly divided into experimental group (34 patients) and control group (36 patients). The experimental group received eight-week aerobic exercise and yoga training. The control group received no training. Sleep Quality Scale, Negative Emotion Scale and Anxiety Self-rating Scale were used to assess the level of sleep and negative emotion before and after exercise intervention. Results After exercise intervention, sleep quality (4.31±1.26), anxiety (36.41±7.32) and negative emotion (2.37±0.50) in the experimental group significantly improved (P<0.01), no similar changes were found in the control group (P<0.05). By examining the mediating effects, negative emotions played a partial mediating role in the association between exercise and sleep quality (t=6.77, P<0.01). Conclusion Exercise intervention significantly improved the quality of sleep and negative emotion among female college students with anxiety. Negative emotions play a partial role in the positive effect of exercise on sleep quality.
Self-injurious behavior among college students and its association with parental rearing styles
CHEN Zheping, WANG Yanqiu, CHEN Liying, WANG Jinfeng, JIN Yuelong, YAO Yingshui
2019, 40(4): 546-549,554. doi: 10.16835/j.cnki.1000-9817.2019.04.019
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Objective To examine epidemiology of self-injurious behavior and explore the association between self-injurious behavior and parental rearing styles, to provide the theoretical basis for the identification, prevention and occurrence of the self-injurious behaviors among adolescents. Methods Stratified cluster sampling was used to survey 3 683 students from three colleges in Wuhu and Huainan by using questionnaire response. Egna Minnen avBarn-dosnauppforstran (EMBU) and demographic characteristics were used by college students to assess their self-injurious behavior and parental rearing styles. Results For college students, the detection rate of reporting of 1-2 self-injurious behavior was 30.4%, and the rate of reporting of 3 or more self-injurious behavior was 11.8%. In terms of the occurrences of self-injurious behavior, gender (χ2=76.98), classification of colleges and universities (χ2=153.71) and the relationship with father (χ2=47.48) and with mother (χ2=40.01) were markedly different (P<0.05). Correlation and regression analysis indicated that the risks leading to self-injurious behavior were involved in medical students, overprotection from father and preference from mother (OR=2.05, 95%CI=1.64-2.55; OR=1.13, 95%CI=1.06-1.20; OR=1.05, 95%CI=1.01-1.09). Conclusion Female students and medical students can be inclined to self-injurious behavior. Parental rearing styles were related to the self-injurious behaviors of college students. Strengthening interaction between students and parents, providing appropriate emotional warmth as well as encouraging the establishment of a good family atmosphere may reduce the occurrence of self-injurious behavior in current college students.
Effects of acceptance and commitment therapy on mental health of high school students:based on the dual-factor model of mental health
CHEN Ying, HU Maorong, LAI Xiong, XU Jing
2019, 40(4): 550-554. doi: 10.16835/j.cnki.1000-9817.2019.04.020
Abstract(459) PDF(35)
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Objective Based on the dual-factor model of mental health, this study aims to explore the effects of acceptance and commitment therapy on the mental health of high school students. Methods During Oct. to Nov. 2017, General Health Questionnaire-12 (GHQ-12) and Depression Anxiety and Stress Scale-21 (DASS-21) was administered among 543 high school students from a middle school in Nanchang. According to the inclusion and exclusion criteria, 20 high school students were screened and were randomly assigned to the intervention group and control group, respectively. The intervention group received one intervention (1.5 h) per week for 8 weeks. The control group did not receive the intervention. Pre-and post-intervention assessment were conducted using the Acceptance and Action Questionnaire-2 nd Edition (AAQ-II), the Cognitive Fusion Questionnaire-Fusion (CFQ-F), the Satisfaction With Life Scale (SWLS), the Positive Affect Scale (PAS), the GHQ-12, and the DASS-21.Results After intervention, the post-test scores of AAQ-II, CFQ-F, GHQ-12, and DASS-21 in the intervention group significantly decreased (t=2.91, 2.47, 4.91, 4.42, P<0.05) and the post-test score on PAS significantly increased (t=-5.27, P<0.01). There were no statistical changes in AAQ-II, CFQ-F, GHQ-12, and DASS-21 scores in the control group after intervention (t=-1.25,-0.09,-0.61,-0.69,-0.81, P>0.05). Conclusion Acceptance and commitment therapy can effectively improve the psychological flexibility and positive emotions, as well as alleviate general psychological distress and negative emotions, and promote the improvement of mental health of high school students.
Observation on the intervention effect of massage loosening method combined with PNF stretching method on the imbalance of neck and shoulder muscles of college students
YANG Kewen, QIAO Jianhua
2019, 40(4): 555-558,562. doi: 10.16835/j.cnki.1000-9817.2019.04.021
Abstract(289) PDF(9)
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Objective To explore the intervention effect of massage relaxation method combined with PNF stretching method on the imbalance of neck and shoulder muscles of college students, and provide a reference for effectively improving the health of neck and shoulder muscles among college students. Methods Totally 84 college students with neck and shoulder muscle imbalance from March 2017 to March 2018 due to prolonged bowing were selected as subjects. They were randomly divided into two groups (n=42): the control group was given regular strength training, and the observation group was provided with more strength training by Massage relaxation method and PNF stretching method was used for therapeutic intervention. Then the degrees of neck and shoulder muscle pain, joint mobility, round shoulder angle, and head extension angle were compared before and after intervention of two groups. Results Compared with the results before intervention, the VAS score of the observation group was significantly lower after the intervention, and there was no significant change in the control group, and the VAS score of the observation group was (3.23±1.29), which was significantly lower than that of the control group (4.26±1.42) (P<0.05). The head extension angle and the round shoulder angle of the observation group respectively were (28.24±4.14) ° and (35.68±6.29) °, and the control group respectively were (32.21±6.27) ° and (41.86±5.38) °. The difference was statistically significant (P<0.05). The neck joint flexion, extension, left-handedness, right-handedness, left flexion, right flexion, left-handed and right-handed motion of the observation group respectively were (67.24±7.15) °, (68.82±4.66) °, (73.21±4.83) °, (73.56±5.13) °, (38.18±5.14) °and (38.85±2.33) °, all significantly higher than the control group (P<0.05). The muscle tension (left), muscle tension (right), muscle stiffness (left), muscle stiffness (right), muscle elasticity (left), and muscle elasticity (right) of the observation group respectively were (10.21±0.63) Hz, (10.13±0.72) Hz, (174.64±18.15) N/m, (164.34±16.73) N/m, 0.74±0.25 and 0.71±0.33, both significantly lower than the control group (P<0.05). Conclusion Massage loosening combined with PNF stretching method combined with conventional strength training can effectively alleviate the pain caused by the imbalance of neck and shoulder muscles of college students, improve head extension and round shoulder angle, correct neck and shoulder posture, and restore neck and shoulders.
Influence of school-level factors and anxiety on injury-prone children
PAN Minyi, LIAO Haining, LIN Shunwei, ZHU Xuhao, ZHOU Shudong
2019, 40(4): 559-562. doi: 10.16835/j.cnki.1000-9817.2019.04.022
Abstract(290) PDF(8)
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Objective To understand the characteristics of injuries among rural children, and to determine the relationships between school-level factors with anxiety among injury-prone children, to provide a reference for making effective measures to prevent and control the injuries. Methods A cross-sectional survey was conducted in the Qingxin District of Qingyuan City. Six primary schools and middle schools were randomly selected from two towns. A total of 5 250 students in grades 3-9 were investigated. Students filled out the questionnaire themselves. Screen for Child Anxiety Related Emotional Disorders (SCARED) was used to assess anxiety. Results Among the 770 rural children who suffered injuries during the past year, the leading cause of injury was falling (44.62%), falling at home (29.61%), getting injuried in low limbs (29.45%), getting injuried by oneself (41.00%) and mainly unintentional injuries (68.66%). About 35.06% of children reported anxiety symptoms. Approximately 14.94% of children were injury-prone type. Significant differences in educational stage, boarding school, fighting involvement, and somatization/panic between injury-prone children were found in control group (P<0.05). The robust Poisson-GEE model showed that primary school students in high grade and middle grade, fighting with classmates, somatic/panic associated with injury risk (PR value was 2.11, 1.75, 1.58 and 1.58, respectively). Conclusion Injury-prone children in rural are affected by school-level factors as well as anxiety symptoms. In addition to safety education, mental health promotion and prevention of school bullying should be adopted in schools.
Body shape changes among children living in Jinuo community
XU Changnan, SUN Guilong, DING Rujia, HU Mei
2019, 40(4): 563-566,571. doi: 10.16835/j.cnki.1000-9817.2019.04.023
Abstract(334) PDF(6)
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Objective To explore body shape changes among Jinuo boys and girls aged 7-12 years during 2011 to 2016, and to fill in the data gaps of the "National Physique Monitoring" and "Chinese Students' Physique and Health" database. Methods Height and weight of children aged 7-12 years living in Jinuo nationality during 2011-2016 were measured. Inter-and intra-individual variation in body mass index (BMI) and BMI growth rate of Jinuo male and female girls were compared. Results From 2011 to 2016, boys and girls aged 7-12 years living in Jinuo community showed an overall increase trend in height. Some temporal and small declines in specific year were also noticed; the overall weight average showed an increasing trend; BMI increased with the age. The trends in boys and girls are basically the same. Growth rate in BMI showed a positive increasing trend. Conclusion During 2011-2016, body shape among boys and girls aged 7-12 years living in Jinuo community is generally thin. All the indicators in body shape show an increasing trend with age, which fits within the basic principal of human growth and development.
Using Mapping Knowledge Domains to analyze research status, hotspots and frontier evolution of school health in China
QIU Fengxia, SUN Guotao, DU Guangyou
2019, 40(4): 567-571. doi: 10.16835/j.cnki.1000-9817.2019.04.024
Abstract(357) PDF(19)
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Objective To reveal intuitively the micro and macro structure of school health research in China, in order to lay a solid foundation for further study. Methods Statistical analyses the current status of 864 high-level journal papers in the field of school health in China by EXCEL and SATI software, author cooperation and organization cooperation, research hotspots and frontier trend knowledge maps were drawn by Citespace. Results The research in the field of school health in China shows a wavy growth trend, the contribution of Chinese Journal of School Health is the biggest (757). Ma Jun, Tao Fangbiao, Wang Zhiyong, Liu Wei, Duan Jiali, Xu Yong are high-yield authors, Peking University, Anhui Medical University, Dalian City and Beijing Center for Disease Control and Prevention are high-yield institutions. Author cooperation and institutional cooperation are relatively loose, and Duan Jiali et al. and Peking University institute of child and adolescent health, respectively, form the largest cooperation community. Status, supervision, rural area, management, surveillance, health education, epidemiology, nutrition, environmental health, infectious diseases, common diseases, and influencing factors, etc. are hot topics in the field. Conclusion Cross-boundary exchanges and cooperation should be strengthened to promote regional coordinated development. Health risk behaviors of children and adolescents, environmental health surveillance and epidemiology of infectious diseases of primary and secondary schools, the school health personnel present situation investigation, children nutrition health and common diseases prevention and control, rural school health supervision and health education countermeasures, and school health management model were the hot topics, prevention of child injury, Internet addiction, and physical and mental health promotion were the leading directions. The commnunication and cooperation between different fields should be strengthened to improve the reginal development.
Application of decision tree and regression technique in the analysis of visual acuity influencing factors in primary and middle school students
XIE Xiaolian, LI Juan, LIU Shanghong, SUN Lijiao, ZHAO Haiping
2019, 40(4): 572-575. doi: 10.16835/j.cnki.1000-9817.2019.04.025
Abstract(477) PDF(17)
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Objective To investigate the visual acuity of primary and middle school students in Ningxia by using decision tree model and logistic regression, and to provide evidence for the prevention and control of visual acuity. Methods Using stratified cluster sampling method, 3 257 children aged 7-18 years were randomly selected from Yinchuan and Wuzhong in Ningxia. Visual acuity test and questionnaire survey were conducted. The C 5.0 algorithm in Clementine12.0 and Logistic regression were used to analyze the factors associated with visual acuity. Results The overall rate of low vision of the middle school of Ningxia was 62.6%, with girls (68.1%) higher than that of boys (56.8%) (P<0.01). There was a significant difference in the prevalence of low vision among different educational stages (P<0.01), with high school students had the highest detection rate (82.2%). Results of decision tree C 5.0 algorithm showed that educational stage, gender, time to do homework after school and frequency of moderate intensity exercise per week associated with poor eyesight of primary and secondary school students. Logistic regression results showed that girls, the distance between the eyes and the computer display screen <66 cm (OR=1.24, 95%CI=1.00-1.52), and the distance between the eyes and the textbook when reading was less than one foot (OR=2.05, 95%CI=1.23-3.40) were positively associated with poor vision. Low grade students and homework time <2 hours after school (OR=0.76, 95%CI=0.62-0.92) were negatively associated with lower risk of poor vision. Conclusion Educational stage, gender and time of homework after school are associated with the visual acuity of primary and secondary school students in Ningxia. It is suggested that prevention of myopia should start from the low-grade students, reducing after-school work for primary and secondary school students, and increasing outdoor activities. All the girls should be encouraged to engage in more outdoor activities, to prevent the occurrence and development of myopia.
Analysis of characteristics of HIV cases aged 15-24 in Jiaxing City
GE Rui, LUO Jianyong, LUO Mingyu, HU Jie, ZHANG Qianqian, WANG Yuanhang, XU Wenxian, ZHU Wutong
2019, 40(4): 576-578. doi: 10.16835/j.cnki.1000-9817.2019.04.026
Abstract(283) PDF(7)
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Objective To understand the epidemiological characteristics and differences of HIV-positive cases among 15-24 years old in Jiaxing city and provide evidence for the development of targeted prevention and control measures. Methods A descriptive epidemiological method was used to analyze the data of HIV cases aged 15-24 reported in Jiaxing from 1999 to 2018. Results A total of 375 cases of young HIV were reported in 1999-2018, with an average age of 21.29±1.90 years, of which 42 were students. The ratio of male to female was 2.47:1.The proportion of foreign household registration was higher (76%, 285 cases). The proportion of off-campus youth cases in total cases showed a downward trend (χ2=8.26, P=0.00), but the proportion of student cases showed an upward trend (χ2=15.73, P<0.01). Off-campus youth cases were mainly heterosexual transmission (59.16%, 197 cases), and the students' cases were mainly homosexual transmission (88.10%, 37 cases). There were significant differences in gender, age, household registration, education level, route of transmission, late detection, CD4 level and source of detection among students and off-campus adolescents (P<0.05). Conclusion The prevalence of AIDS in adolescents and students is worthy of attention. The characteristics of adolescents inside and outside the school are different. Targeted prevention measures should be taken to reduce the harm of AIDS to young people.
Analysis of the two-week case rate among primary and middle school students from poor areas in 5 provinces of middle and central China
DAI Jie, WANG Zhenghe, WANG Junyi, LI Yanhui, ZHAO Haiping, MA Jun
2019, 40(4): 579-581. doi: 10.16835/j.cnki.1000-9817.2019.04.027
Abstract(308) PDF(7)
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Objective To understand the two-week case rate of children and teenagers in the poor areas of middle and western China, and to provide a scientific basis for clarifying the focus of medical and health services in the future and deepening the new medical reform system. Methods The method of random cluster sampling was used to select the research object, the condition of catching diseases among primary and middle students was investigated through a questionnaire on two-week case rate. and chi-square test was adopted to compare the difference between the groups of two-week health situation. Results The two-week prevalence rate of primary and middle school students in poor areas in central and western China was 16.2%. The top three systemic diseases were respiratory system (accounting for 58.4%), digestive system (accounting for 13.5%) and immune system (accounting for 1.8%). The prevalence of different demographic characteristics was also found with difference: the two-week prevalence rates (15.6% and 16.7%) for both men and women were lower than the results of the 2008 national survey, but the difference was not statistically significant (χ2=3.17, P=0.05); the case rates in different age groups decreased with a undulating curve, the 9-10 age group was the highest (20.1%), the difference was statistically significant (χ2=33.26, P<0.01); the differences of case rates in different ethnic groups were of statistical significance (χ2=78.33, P<0.05), the prevalence of LiSu ethnic group was the highest (24.6%); The main diseases (symptoms) were different in different provinces. Conclusion The demand for health care among primary and middle school students in poor areas of middle and western China is significantly higher than the results of a national survey of 5-24-year-old residents. Thus, the close attention should be paid to providing a reasonable and sufficient health service.
Effects of comprehensive intervention on glucose and lipid metabolism, liver and kidney function and cardiovascular function in obese adolescents
YAO Meng, BAI Shuang, LI Xulong, ZHANG Yifan, TANG Donghui
2019, 40(4): 582-585. doi: 10.16835/j.cnki.1000-9817.2019.04.028
Abstract(379) PDF(13)
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Objective To investigate the effects of exercise combined with dietary intervention on glucose and lipid metabolism, liver and kidney function and cardiovascular function in obese adolescents. Methods Seventy-one obese adolescents were enrolled in this study. Six weeks of exercise combined with dietary intervention were performed to determine anthropometry, glucose and lipid metabolism, liver and kidney function and cardiovascular function before and after intervention. Results After 6 weeks of comprehensive intervention, in addition to significant improvement in anthropometry indicators, fasting insulin [ (18.76±11.46 vs 11.32±6.54) uU/L], LDL-C [ (2.96±0.69 vs 2.22±0.62) mmol/L], TG [ (1.57±0.82 vs 0.89±0.37) mmol/L] and TC [ (4.52±0.76 vs 3.53±0.62) mmol/L] decreased significantly and insulin resistance improved significantly. AST [ (36.1±32.28 vs 22.89±7.27) U/L], ALT [ (57.42±61.25 vs 27.86±22.12) U/L], blood urea nitrogen [ (4.78±0.89 vs 3.44±0.79) mmol/L] and uric acid [ (498.83±120.6 vs 471.07±120.96) mmol/L] were significantly decreased and the detection rates of fatty liver and kidney were significantly decreased (P<0.05), RHI (1.34±0.28 vs 1.69±0.45) and nitric oxide/endothelin-1 (ET-1) (1.69±0.41 vs 2.67±0.86) significantly increased and atherogenic index (3.06±0.96 vs 2.58±0.80) significantly decreased (P<0.01). Conclusion The comprehensive intervention of exercise combined with diet can effectively improve anthropometry indicators, glycolipid metabolism, liver and kidney function as well as cardiovascular function of obese adolescents.
2019, 40(4): 586-589. doi: 10.16835/j.cnki.1000-9817.2019.04.029
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2019, 40(4): 590-592. doi: 10.16835/j.cnki.1000-9817.2019.04.030
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2019, 40(4): 593-595. doi: 10.16835/j.cnki.1000-9817.2019.04.031
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2019, 40(4): 595-597. doi: 10.16835/j.cnki.1000-9817.2019.04.032
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2019, 40(4): 598-601. doi: 10.16835/j.cnki.1000-9817.2019.04.033
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2019, 40(4): 601-605. doi: 10.16835/j.cnki.1000-9817.2019.04.034
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2019, 40(4): 606-608. doi: 10.16835/j.cnki.1000-9817.2019.04.035
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2019, 40(4): 608-611. doi: 10.16835/j.cnki.1000-9817.2019.04.036
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2019, 40(4): 612-613. doi: 10.16835/j.cnki.1000-9817.2019.04.037
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2019, 40(4): 614-615. doi: 10.16835/j.cnki.1000-9817.2019.04.038
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2019, 40(4): 616-618. doi: 10.16835/j.cnki.1000-9817.2019.04.039
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2019, 40(4): 619-622. doi: 10.16835/j.cnki.1000-9817.2019.04.040
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2019, 40(4): 622-624. doi: 10.16835/j.cnki.1000-9817.2019.04.041
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2019, 40(4): 625-626. doi: 10.16835/j.cnki.1000-9817.2019.04.042
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2019, 40(4): 627-631. doi: 10.16835/j.cnki.1000-9817.2019.04.043
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2019, 40(4): 631-633. doi: 10.16835/j.cnki.1000-9817.2019.04.044
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2019, 40(4): 634-637. doi: 10.16835/j.cnki.1000-9817.2019.04.045
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2019, 40(4): 638-640. doi: 10.16835/j.cnki.1000-9817.2019.04.046
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