Epidemiological trends analysis of syphilis among students in Yunnan Province from 2005 to 2023

TAN Min; CHANG Litao; ZHANG Wanyue; HUANG Dafeng; LIU Chunyan; ZHANG Lifang; YANG Yanling

doi:10.16835/j.cnki.1000-9817.2025134

Volume 46 Issue 5

May 2025

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TAN Min, CHANG Litao, ZHANG Wanyue, HUANG Dafeng, LIU Chunyan, ZHANG Lifang, YANG Yanling. Epidemiological trends analysis of syphilis among students in Yunnan Province from 2005 to 2023[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2025, 46(5): 737-740. doi: 10.16835/j.cnki.1000-9817.2025134

Citation:

TAN Min, CHANG Litao, ZHANG Wanyue, HUANG Dafeng, LIU Chunyan, ZHANG Lifang, YANG Yanling. Epidemiological trends analysis of syphilis among students in Yunnan Province from 2005 to 2023[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2025, 46(5): 737-740. doi: 10.16835/j.cnki.1000-9817.2025134

Citation:

TAN Min, CHANG Litao, ZHANG Wanyue, HUANG Dafeng, LIU Chunyan, ZHANG Lifang, YANG Yanling. Epidemiological trends analysis of syphilis among students in Yunnan Province from 2005 to 2023[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2025, 46(5): 737-740. doi: 10.16835/j.cnki.1000-9817.2025134

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Epidemiological trends analysis of syphilis among students in Yunnan Province from 2005 to 2023

doi: 10.16835/j.cnki.1000-9817.2025134

1.
School Health Section, Yunnan Provincial Center for Disease Control and Prevention, Kunming (650500), Yunnan Province, China

Received Date: 2024-10-23
Rev Recd Date: 2024-12-16

Available Online: 2025-06-07

Publish Date: 2025-05-25

Abstract

Abstract

Objective To analyze epidemiological trends and changing characteristics of syphilis among students in Yunnan Province from 2005 to 2023, so as to provide evidence for the comprehensive prevention and control of syphilis in schools. Methods The case data of syphilis among students in Yunnan Province from 2005 to 2023 were obtained from the China Information System for Disease Control and Prevention. The Joinpoint regression model was used to conduct a time trend analysis of the reported incidence rate of syphilis. Results From 2005 to 2023, a cumulative total of 3 191 cases of syphilis were reported in schools in Yunnan Province(1 248 male cases and 1 943 female cases). The reported incidence rate rose continuously from 0.17/100 000 in 2005 to 8.26/100 000 in 2023, with an average annual percent change (AAPC) of 24.89%(Z=13.18, P < 0.01). The reported incidence rate was higher in female students than in male students (χ²=229.48, P < 0.05). The incidence rates in the primary school, junior high school, senior high school and higher education were 0.21/100 000, 2.42/100 000, 4.45/100 000 and 6.29/100 000 respectively, and the difference was statistically significant(χ²=3 432.84, P < 0.05). The average annual growth rate was the highest in the junior high school stage(AAPC=30.68%, Z=7.57, P < 0.05), followed by the senior high school stage (AAPC=24.28%, Z=5.70, P < 0.05).The reported incidence rate of primary and secondary syphilis increased from 0.12/100 000 in 2005 to 2.06/100 000 in 2023, with an AAPC of 16.86% (Z=4.57, P < 0.05). Conclusions The overall reported incidence rate of syphilis among students in schools in Yunnan Province shows a sustained upward trend, with the most rapid annual increase observed in junior high schools. Schools should prioritize syphilis education and expand awareness campaigns to curb transmission.
- Syphilis,
- Epidemiologic studies,
- Regression analysis,
- Students

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References(22)

References

[1]	ARANDO L M, OTERO G L. Syphilis[J]. Engl Ed, 2019, 37(6): 398-404.
[2]	马宁, 孙笠翔, 康续, 等. 2006—2020年辽宁省10~19岁青少年梅毒和淋病发病趋势的Joinpoint回归分析[J]. 中华预防医学杂志, 2022, 56(9): 1323-1326. doi: 10.3760/cma.j.cn112150-20211127-01091 MA N, SUN L X, KANG X, et al. Joinpoint regression analysis of the incidence trend of syphilis and gonorrhea among adolescents aged 10-19 in Liaoning Province from 2006 to 2020[J]. Chin J Prev Med, 2022, 56(9): 1323-1326. (in Chinese) doi: 10.3760/cma.j.cn112150-20211127-01091
[3]	全国人民代表大会常务委员会. 中华人民共和国传染病防治法[Z]. 北京: 中国法制出版社, 2013. Standing Committee of the National People's Congress. Law of the PRC on prevention and treatment of infectious diseases[Z]. Beijing: China Legal Publishing House, 2013. (in Chinese)
[4]	中华人民共和国卫生部. 梅毒诊断: WS 273—2007[S]. 北京: 中国标准出版社, 2007. Ministry of Health of the PRC. Diagnosis of syphilis: WS 273-2007[S]. Beijing: Standards Press of China, 2007. (in Chinese)
[5]	中华人民共和国国家卫生和计划生育委员会. 梅毒诊断: WS 273—2018[S]. 北京: 中国标准出版社, 2018. National Health and Family Planning Commission of the PRC. Diagnosis of syphilis: WS 273-2018[S]. Beijing: Standards Press of China, 2018. (in Chinese)
[6]	费丽娟, 沈云良, 吴李梅, 等. 2012—2021年浙江省10~19岁人群梅毒流行趋势分析[J]. 中国艾滋病性病, 2023, 29(7): 825-827. FEI L J, SHEN Y L, WU L M, et al. Analysis of the trend of syphilis among population aged 10-19 in Zhejiang Province from 2012 to 2021[J]. Chin J AIDS STD, 2023, 29(7): 825-827. (in Chinese)
[7]	朱考考, 冯玉婷, 许玉军. 2015—2020年海南省10~19岁人群梅毒流行病学分析[J]. 中国艾滋病性病, 2022, 28(5): 588-589. ZHU K K, FENG Y T, XU Y J. Analysis of the trend of syphilis among population aged 10-19 in Hainan Province from 2015 to 2020[J]. Chin J AIDS STD, 2022, 28(5): 588-589. (in Chinese)
[8]	吴月琳, 朱文倩, 岳晓丽, 等. 新型冠状病毒肺炎流行对我国梅毒病例报告结果的影响[J]. 中华流行病学杂志, 2022, 43(12): 2015-2020. doi: 10.3760/cma.j.cn112338-20220920-00794 WU Y L, ZHU W Q, YUE X L, et al. Impact of COVID-19 epidemic on syphilis case reporting in China[J]. Chin J Epidemiol, 2022, 43(12): 2015-2020. (in Chinese) doi: 10.3760/cma.j.cn112338-20220920-00794
[9]	SIEVING R E, GEWIRTZ O'BRIEN J R, et al. Sexually transmitted diseases among USA adolescents patterns, clinical considerations, and prevention[J]. Nurs Clin North Am, 2019, 54: 207-225. doi: 10.1016/j.cnur.2019.02.002
[10]	姜路明, 朱匡纪, 楼秒芬, 等. 金华市婺城区儿童青少年梅毒流行特征分析[J]. 中国初级卫生保健, 2018, 32(12): 42-44. doi: 10.3969/j.issn.1001-568X.2018.12.0015 JIANG L M, ZHU K J, LOU M F, et al. Epidemiological characteristics analysis of syphilis among children and adolescents in Wucheng District of Jinhua[J]. Chin Prim Health Care, 2018, 32(12): 42-44. (in Chinese) doi: 10.3969/j.issn.1001-568X.2018.12.0015
[11]	李海兰, 杨慧杰, 罗毓仪, 等. 中小学性教育现状与对策思考[J]. 中国学校卫生, 2022, 43(7): 965-969. doi: 10.16835/j.cnki.1000-9817.2022.07.002 LI H L, YANG H J, LUO Y Y, et al. Current status and considerations of sexuality education in primary and secondary school[J]. Chin J Sch Health, 2022, 43(7): 965-969. (in Chinese) doi: 10.16835/j.cnki.1000-9817.2022.07.002
[12]	孙敏, 傅育嵩, 张星, 等. 2013—2022年成都市金牛区梅毒流行趋势分析[J]. 中国初级卫生保健, 2023, 37(7): 92-95. doi: 10.3969/j.issn.1001-568X.2023.07.0025 SUN M, FU Y S, ZHANG X, et al. Analysis of epidemiological tendency of syphilis in Jinniu District of Chengdu from 2013 to 2022[J]. Chin Prim Health Care, 2023, 37(7): 92-95. (in Chinese) doi: 10.3969/j.issn.1001-568X.2023.07.0025
[13]	陆瑶, 吴静, 胡翼飞. 中国青年学生HIV和梅毒感染率Meta分析[J]. 中国艾滋病性病, 2017, 23(6): 524-528. LU Y, WU J, HU Y F. HIV and syphilis prevalence among high school and college students in China: a Meta-analysis[J]. Chin J AIDS STD, 2017, 23(6): 524-528. (in Chinese)
[14]	汪志辉, 林少玲. 漳州市15~24岁青少年艾滋病流行病学特征[J]. 海峡预防医学杂志, 2021, 27(4): 21-23. WANG Z H, LIN S L. Epidemiological characteristics of HIV among adolescents aged 15-24 in Zhangzhou City[J]. Strait J Prev Med, 2021, 27(4): 21-23. (in Chinese)
[15]	陈黎跃, 刘秀红, 董文斌, 等. 2005—2019年玉溪市10~24岁青少年性传播疾病流行特征与趋势分析[J]. 中国皮肤性病学杂志, 2021, 35(1): 57-65. CHEN L Y, LIU X H, DONG W B, et al. Analysis of epidemiological trends and characteristics of sexual transmitted disease among adolescents aged 10 to 24 years in Yuxi City from 2005 to 2019[J]. Chin J Dermatovenereol, 2021, 35(1): 57-65. (in Chinese)
[16]	王成, 赵培祯, 沈鸿程, 等. 珠三角地区性病门诊青少年就诊者性病HIV感染现状及影响因素分析[J]. 中国艾滋病性病, 2018, 24(6): 624-625. WANG C, ZHAO P Z, SHEN H C, et al. Analysis of the current status and influencing factors of STD infection and HIV among adolescents at sexually transmitted disease clinics in the Pearl Rive Delta Region[J]. Chin J AIDS STD, 2018, 24(6): 624-625. (in Chinese)
[17]	中国疾病预防控制中心性病艾滋病预防控制中心. 2023年12月全国艾滋病性病疫情[J]. 中国艾滋病性病, 2024, 30(3): 225. Center for STD/AIDS Prevention and Control of Chinese Center for Disease Control and Prevention. The AIDS and STD epidemic situation in the whole country in December 2023[J]. Chin J AIDS STD, 2024, 30(3): 225. (in Chinese)
[18]	郭艳, 张小斌, 张秀劼, 等. 云南省2004—2021年梅毒流行特征和发病趋势[J]. 中国艾滋病性病, 2023, 29(9): 1024-1028. GUO Y, ZHANG X B, ZHANG X J, et al. Epidemiological characteristics and incidence trend of syphilis in Yunnan Province from 2004 to 2021[J]. Chin J AIDS STD, 2023, 29(9): 1024-1028. (in Chinese)
[19]	徐文婕, 白承续, 陈东妮, 等. 2010—2022年北京市青少年部分性传播疾病流行病学特征分析[J]. 中国生育健康杂志, 2024, 35(5): 457-461. XU W J, BAI C X, CHEN D N, et al. Analysis of the epidemiological characteristics of some sexually transmitted diseases among adolescents in Beijing from 2010 to 2022. [J]. Chin J Reprod Health, 2024, 35(5): 457-461. (in Chinese)
[20]	李乐, 戚广浩, 李震, 等. 北京市通州区2009—2021年梅毒流行特征[J]. 中国卫生检验杂志, 2022, 32(17): 2151-2153. LI L, QI G H, LI Z, et al. Epidemiological analysis of syphilis in Tongzhou District, Beijing City from 2009 to 2021[J]. Chin J Health Lab Technol, 2022, 32(17): 2151-2153. (in Chinese)
[21]	谭天宇, 贺亚萍, 郭晓嘉, 等. 重庆市2015—2020年梅毒流行特征分析[J]. 中国艾滋病性病, 2022, 28(9): 1087-1088. TAN T Y, HE Y P, GUO X J, et al. Epidemiological analysis of syphilis in Chongqing from 2015 to 2020[J]. Chin J AIDS STD, 2022, 28(9): 1087-1088. (in Chinese)
[22]	利超强, 陈发颖, 陈清. 2011—2020年肇庆市梅毒流行病学特征变化[J]. 实用医学杂志, 2022, 38(13): 1685-1689. LI C Q, CHEN F Y, CHEN Q. Changes in the epidemiological characteristics of syphilis in Zhaoqing City from 2011 to 2020[J]. J Pract Med, 2022, 38(13): 1685-1689. (in Chinese)