Association between high body fat mass and elevated blood pressure in children

YAN Yujiao; YANG Hui; CHENG Anlan; ZHAO Min; XI Bo

doi:10.16835/j.cnki.1000-9817.2024309

Volume 45 Issue 10

Oct. 2024

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Article Navigation > CHINESE JOURNAL OF SCHOOL HEALTH > 2024 > 45(10): 1393-1398

YAN Yujiao, YANG Hui, CHENG Anlan, ZHAO Min, XI Bo. Association between high body fat mass and elevated blood pressure in children[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2024, 45(10): 1393-1398. doi: 10.16835/j.cnki.1000-9817.2024309

Citation:

YAN Yujiao, YANG Hui, CHENG Anlan, ZHAO Min, XI Bo. Association between high body fat mass and elevated blood pressure in children[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2024, 45(10): 1393-1398. doi: 10.16835/j.cnki.1000-9817.2024309

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Association between high body fat mass and elevated blood pressure in children

doi: 10.16835/j.cnki.1000-9817.2024309

YAN Yujiao^{1, 2},
YANG Hui^{1, 2},
CHENG Anlan^{1, 2},
ZHAO Min³,
XI Bo^{1, 2
,
,}

1.
Department of Epidemiology/Department of Maternal, Child and Adolescent Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan (250012), Shandong Province, China

Received Date: 2024-05-06
Rev Recd Date: 2024-07-23

Available Online: 2024-11-02

Publish Date: 2024-10-25

Abstract

Abstract

Objective To examine the association between high body fat mass and elevated blood pressure in children, so as to provide scientific evidence for the prevention and treatment of childhood hypertension. Methods Participants were recruited from the second follow-up survey of the Huantai Childhood Cardiovascular Health Cohort Study conducted in 2021 in Huantai County, Zibo City, Shandong Province, China. A total of 1 266 children aged 10-15 years old were included. The study categorized fat mass (FM), fat mass percentage (FMP), fat mass index (FMI), subcutaneous fat mass (SFM), and visceral fat mass (VFM), respectively, into normal and elevated groups based on age- and gender-specific median values (P₅₀) in the study population. The multivariate Logistic regression model was used to analyze the association between the status of body mass and elevated blood pressure. A restrictive cubic spline (RCS) model was used to examine the dose-response relationship between the levels of body mass and elevated blood pressure. Results The detection rates of elevated blood pressure in children with elevated FM, elevated FMP, elevated FMI, elevated SFM, and elevated VFM were all significantly higher than those in the normal group (P < 0.05). After adjusting for all potential covariates, compared to the normal group, elevated FM (OR=4.51, 95%CI=3.28-6.28), elevated FMP (OR=4.51, 95%CI=3.28-6.27), elevated FMI (OR=4.40, 95%CI=3.20-6.12), elevated SFM (OR=4.52, 95%CI=3.29-6.30), and elevated VFM (OR=4.48, 95%CI=3.28-6.18) were all positively associated with elevated blood pressure (P < 0.05). The RCS analysis demonstrated that the high levels of FM, FMP, FMI, and SFM showed linear dose-response relationships with elevated blood pressure (P_non-linear>0.05), and elevated VFM was associated with elevated blood pressure in a nonlinear dose-response relationship (P_non-linear < 0.05). Conclusions Children with elevated body fat have a higher risk of elevated blood pressure. There was a dose-response relationship between high body mass content and elevated blood pressure in children. It is essential to take appropriate measures to reduce the elevated body fat in children, in order to prevent the occurrence of high elevated blood pressure in children.
- Body fat distribution,
- Blood pressure,
- Regression analysis,
- Child

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References(31)

References

[1]	SONG P, ZHANG Y, YU J, et al. Global prevalence of hypertension in children: a systematic review and Meta-analysis[J]. JAMA Pediatr, 2019, 173(12): 1154-1163. doi: 10.1001/jamapediatrics.2019.3310
[2]	陈力, 张奕, 马涛, 等. 2010—2019年中国7~17岁汉族儿童青少年正常高值血压和血压偏高的流行趋势[J]. 中华预防医学杂志, 2023, 57(4): 499-507. CHEN L, ZHANG Y, MA T, et al. Prevalence trend of high normal blood pressure and elevated blood pressure in Chinese Han children and adolescents aged 7-17 years from 2010 to 2019[J]. Chin J Prev Med, 2023, 57(4): 499-507. (in Chinese)
[3]	孙嘉鸿, 杨丽丽, 羊柳, 等. 儿童青少年期血压偏高与心血管系统损害关联的研究进展[J]. 中华预防医学杂志, 2020, 54(12): 1473-1477. doi: 10.3760/cma.j.cn112150-20200610-00856 SUN J H, YANG L L, YANG L, et al. Elevated blood pressure in childhood or adolescence and early cardiovascular damage[J]. Chin J Prev Med, 2020, 54(12): 1473-1477. (in Chinese) doi: 10.3760/cma.j.cn112150-20200610-00856
[4]	JUHOLA J, MAGNUSSEN C G, BERENSON G S, et al. Combined effects of child and adult elevated blood pressure on subclinical atherosclerosis: the international childhood cardiovascular cohort consortium[J]. Circulation, 2013, 128(3): 217-224. doi: 10.1161/CIRCULATIONAHA.113.001614
[5]	许传先, 杜春晓, 吴国荣, 等. 中国儿童青少年高血压患病率及影响因素Meta分析[J]. 现代预防医学, 2021, 48(23): 4276-4280. doi: 10.3969/j.issn.1003-8507.2021.23.xdyfyx202123012 XU C X, DU C X, WU G R, et al. Meta analysis of prevalence and influencing factors of hypertension in Chinese children and adolescents[J]. Mod Prev Med, 2021, 48(23): 4276-4280. (in Chinese) doi: 10.3969/j.issn.1003-8507.2021.23.xdyfyx202123012
[6]	YANG Y, DAI J, MIN J, et al. Prevalence trends of hypertension and influence factors among children and adolescents aged 7-17 years in China, 2011-2015: a serial cross-sectional study[J]. Front Public Health, 2022, 10: 887285. doi: 10.3389/fpubh.2022.887285
[7]	FRUHBECK G, BUSETTO L, DICKER D, et al. The ABCD of obesity: an EASO position statement on a diagnostic term with clinical and scientific implications[J]. Obes Facts, 2019, 12(2): 131-136. doi: 10.1159/000497124
[8]	NG B K, LIU Y E, WANG W, et al. Validation of rapid 4-component body composition assessment with the use of dual-energy X-ray absorptiometry and bioelectrical impedance analysis[J]. Am J Clin Nutr, 2018, 108(4): 708-715. doi: 10.1093/ajcn/nqy158
[9]	STAIANO A E, KATZMARZYK P T. Ethnic and sex differences in body fat and visceral and subcutaneous adiposity in children and adolescents[J]. Int J Obes (Lond), 2012, 36(10): 1261-1269. doi: 10.1038/ijo.2012.95
[10]	CHEN F, LIU J, YAN Y, et al. Abnormal metabolic phenotypes among urban Chinese children: epidemiology and the impact of DXA-measured body composition[J]. Obesity (Silver Spring), 2019, 27(5): 837-844. doi: 10.1002/oby.22426
[11]	吴容, 尤映彬, 吴龙飞, 等. 深圳市某区6~9岁儿童体脂成分与高血压和血脂异常的关系[J]. 疾病预防控制通报, 2022, 37(2): 17-21. WU R, YOU Y B, WU L F, et al. Relationship between body fat composition and hypertension and dyslipidemia among the children aged 6-9 years in a district of Shenzhen[J]. Bull Dis Control Prev, 2022, 37(2): 17-21. (in Chinese)
[12]	杨丽丽, 张茜, 张艳青, 等. 山东省淄博市桓台儿童心血管健康随访队列设计方案[J]. 中华预防医学杂志, 2020, 54(12): 1461-1464. doi: 10.3760/cma.j.cn112150-20200610-00857 YANG L L, ZHANG Q, ZHANG Y Q, et al. Design of Huantai childhood cardiovascular health cohort study in Zibo City, Shandong Province[J]. Chin J Prev Med, 2020, 54(12): 1461-1464. (in Chinese) doi: 10.3760/cma.j.cn112150-20200610-00857
[13]	PARUTHI S, BROOKS L J, DAMBROSIO C, et al. Recommended amount of sleep for pediatric populations: a consensus statement of the American Academy of Sleep Medicine[J]. J Clin Sleep Med, 2016, 12(6): 785-786. doi: 10.5664/jcsm.5866
[14]	STRASBURGER V C, HOGAN M J, MULLIGAN D A, et al. Children, adolescents, and the media[J]. Pediatrics, 2013, 132(5): 958-961. doi: 10.1542/peds.2013-2656
[15]	WHO. Global recommendations on physical activity for healh[EB/OL]. (2024-06-26)[2024-07-22]. https://www.who.int/news-room/fact-sheets/detail/physical-activity.
[16]	WANG D D, LI Y, BHUPATHIRAJU S N, et al. Fruit and vegetable intake and mortality: results from 2 prospective cohort studies of US men and women and a Meta-analysis of 26 cohort studies[J]. Circulation, 2021, 143(17): 1642-1654. doi: 10.1161/CIRCULATIONAHA.120.048996
[17]	YANG L, BOVET P, LIU Y, et al. Consumption of carbonated soft drinks among young adolescents aged 12 to 15 years in 53 low- and middle-income countries[J]. Am J Public Health, 2017, 107(7): 1095-1100. doi: 10.2105/AJPH.2017.303762
[18]	MENG L, ZHAO D, PAN Y, et al. Validation of Omron HBP-1300 professional blood pressure monitor based on auscultation in children and adults[J]. BMC Cardiovasc Disord, 2016, 16: 9. doi: 10.1186/s12872-015-0177-z
[19]	范晖, 闫银坤, 米杰. 中国3~17岁儿童性别、年龄别和身高别血压参照标准[J]. 中华高血压杂志, 2017, 25(5): 428-435. FAN H, YAN Y K, MI J. Updating blood pressure references for Chinese children aged 3-17 years[J]. Chin J Hypertens, 2017, 25(5): 428-435. (in Chinese)
[20]	TEBAR W R, RITTI-DIAS R M, FARAH B Q, et al. High blood pressure and its relationship to adiposity in a school-aged population: body mass index vs waist circumference[J]. Hypertens Res, 2018, 41(2): 135-140. doi: 10.1038/hr.2017.93
[21]	SARRIA A, MORENO L A, GARCIA-LLOP L A, et al. Body mass index, triceps skinfold and waist circumference in screening for adiposity in male children and adolescents[J]. Acta Paediatr, 2001, 90(4): 387-392. doi: 10.1111/j.1651-2227.2001.tb00437.x
[22]	BAI L, ZHOU J, TONG L, et al. Association between body composition and blood pressure in normal-weight Chinese children and adolescents[J]. BMC Pediatr, 2022, 22(1): 240. doi: 10.1186/s12887-022-03289-z
[23]	陈芳芳, 刘军延, 黄贵民, 等. 中国7个城市3~17岁儿童青少年体成分调查[J]. 中华流行病学杂志, 2020, 41(2): 213-219. CHEN F F, LIU J Y, HUANG G M, et al. Developmental characteristics on body composition in Chinese urban children and adolescents aged 3-17 years old[J]. Chin J Epidemiol, 2020, 41(2): 213-219. (in Chinese)
[24]	LI H, HUANG T, LIU J, et al. Body fat indicators perform better than body mass index in identifying abnormal lipid profiles in boys but not in girls[J]. Pediatr Res, 2019, 85(5): 617-624. doi: 10.1038/s41390-019-0287-x
[25]	BRION M A, NESS A R, DAVEY S G, et al. Association between body composition and blood pressure in a contemporary cohort of 9-year-old children[J]. J Hum Hypertens, 2007, 21(4): 283-290. doi: 10.1038/sj.jhh.1002152
[26]	杨清梅, 马萍, 张浩, 等. 银川市中学生体质指数、腰围、体脂百分比与血压异常研究[J]. 宁夏医科大学学报, 2021, 43(2): 156-160. YANG Q M, MA P, ZHANG H, et al. Study on body mass index, waist circumference, body fat percentage and abnormal blood pressure of middle school students in Yinchuan[J]. J Ningxia Med Univ, 2021, 43(2): 156-160. (in Chinese)
[27]	杨东玲, 周芳, 孙力菁, 等. 上海市初中生体脂率与血压偏高的关联[J]. 中国学校卫生, 2021, 42(5): 746-750. YANG D L, ZHOU F, SUN L J, et al. Relationship between body fat percentage and high blood pressure among junior high school students in Shanghai[J]. Chin J Sch Health, 2021, 42(5): 746-750. (in Chinese)
[28]	XU R Y, ZHOU Y Q, ZHANG X M, et al. Body mass index, waist circumference, body fat mass, and risk of developing hypertension in normal-weight children and adolescents[J]. Nutr Metab Cardiovasc Dis, 2018, 28(10): 1061-1066. doi: 10.1016/j.numecd.2018.05.015
[29]	ABRAHAM T M, PEDLEY A, MASSARO J M, et al. Association between visceral and subcutaneous adipose depots and incident cardiovascular disease risk factors[J]. Circulation, 2015, 132(17): 1639-1647. doi: 10.1161/CIRCULATIONAHA.114.015000
[30]	KOTANI K, TOKUNAGA K, FUJIOKA S, et al. Sexual dimorphism of age-related changes in whole-body fat distribution in the obese[J]. Int J Obes Relat Metab Disord, 1994, 18(4): 202-207.
[31]	HAYASHI T, BOYKO E J, LEONETTI D L, et al. Visceral adiposity is an independent predictor of incident hypertension in Japanese Americans[J]. Ann Intern Med, 2004, 140(12): 992-1000. doi: 10.7326/0003-4819-140-12-200406150-00008