Epidemiological characteristics and genotype of norovirus outbreaks in schools in Xicheng District of Beijing from 2017 to 2022

LIU Xiaoxiao; HUANG Yanhong; CHU Yanhui; SUN Jingyi; YANG Xiong; KONG Qingzheng; JI Yanli; GAO Zhiyong

doi:10.16835/j.cnki.1000-9817.2024155

Volume 45 Issue 5

May 2024

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Article Navigation > CHINESE JOURNAL OF SCHOOL HEALTH > 2024 > 45(5): 704-707

LIU Xiaoxiao, HUANG Yanhong, CHU Yanhui, SUN Jingyi, YANG Xiong, KONG Qingzheng, JI Yanli, GAO Zhiyong. Epidemiological characteristics and genotype of norovirus outbreaks in schools in Xicheng District of Beijing from 2017 to 2022[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2024, 45(5): 704-707. doi: 10.16835/j.cnki.1000-9817.2024155

Citation:

LIU Xiaoxiao, HUANG Yanhong, CHU Yanhui, SUN Jingyi, YANG Xiong, KONG Qingzheng, JI Yanli, GAO Zhiyong. Epidemiological characteristics and genotype of norovirus outbreaks in schools in Xicheng District of Beijing from 2017 to 2022[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2024, 45(5): 704-707. doi: 10.16835/j.cnki.1000-9817.2024155

Citation:

LIU Xiaoxiao, HUANG Yanhong, CHU Yanhui, SUN Jingyi, YANG Xiong, KONG Qingzheng, JI Yanli, GAO Zhiyong. Epidemiological characteristics and genotype of norovirus outbreaks in schools in Xicheng District of Beijing from 2017 to 2022[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2024, 45(5): 704-707. doi: 10.16835/j.cnki.1000-9817.2024155

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Epidemiological characteristics and genotype of norovirus outbreaks in schools in Xicheng District of Beijing from 2017 to 2022

doi: 10.16835/j.cnki.1000-9817.2024155

1.
Department of Infectious Disease and Endemic Disease Control, Xicheng District Center for Disease Prevention and Control, Beijing (100120), China

Received Date: 2023-12-01
Rev Recd Date: 2024-02-19

Available Online: 2024-05-30

Publish Date: 2024-05-25

Abstract

Abstract

Objective To analyze the epidemiological and molecular characteristics of norovirus outbreaks in schools in Xicheng District of Beijing from 2017 to 2022, so as to provide evidence for the prevention and control of norovirus outbreaks in schools. Methods Data of norovirus outbreaks in schools in Xicheng District, Beijing during 2017 to 2022 were collected and analyzed by descriptive epidemiological methods. Real-time PCR was used to detect the nucleic acid of group GⅠ and GⅡ norovirus, the positive norovirus nucleic acid samples were sent to Beijing Center for Disease Control and Prevention for molecular typing. Results From 2017 to 2022, 185 norovirus outbreaks were reported in schools in Xicheng District, including 166 cluster outbreaks and 19 outbreaks. A total of 2 044 cases were reported, with a total attack rate of 13.92%. There were two peaks in the outbreak time, which were from March to June after the spring semester and from October to December after autumn semester. Primary schools were the most common place of occurrence (101 cases), followed by nursery institutions (68 cases) and secondary schools (16 cases). There were statistically significant differences in the incidence rates among different sites(12.37%, 22.78%, 8.47%, χ²=263.34, P < 0.01). There were significant differences in the incidence of vomiting, diarrhea, nausea and stomachache among different students (χ²=263.33, 90.58, 20.42, 30.29, P < 0.01). Vomiting was the main symptom in primary school and nursery school children (96.41%, 98.28%), and the diarrhea rate was higher in middle school students (68.22%). The outbreaks were mainly caused by type GⅡ norovirus. The genotype from 2017 to 2021 showed the characteristics of diversity, mainly GⅡ.2[P16], but there was no significant advantage for the GⅡ.2 [P16] during 2019 to 2021. Conclusions The norovirus outbreak in schools in Xicheng district of Beijing from 2017 to 2022 are mainly caused by GⅡ type genome. The main genotype is GⅡ.2[P16]. Norovirus infection mainly occurred in primary schools and kindergartens. For the vulnerable populations, it is necessary to improve the capacity to early identification, student infectious disease management, active infection control and prevention measures, and pathogen surveillance and sporadic case monitoring.
- Enterovirus infections,
- Disease outbreaks,
- Genes,
- Incidence,
- Student health services

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References(20)

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