Epidemiological and etiological characteristics of hand-foot-mouth disease in Tongren City from 2018 to 2022

WU Dingguo; YU Yang; ZHANG Junli; GAO Qianrong

doi:10.16835/j.cnki.1000-9817.2023.12.029

Volume 44 Issue 12

Dec. 2023

Turn off MathJax

Article Contents

Article Navigation > CHINESE JOURNAL OF SCHOOL HEALTH > 2023 > 44(12): 1898-1901

WU Dingguo, YU Yang, ZHANG Junli, GAO Qianrong. Epidemiological and etiological characteristics of hand-foot-mouth disease in Tongren City from 2018 to 2022[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2023, 44(12): 1898-1901. doi: 10.16835/j.cnki.1000-9817.2023.12.029

Citation:

WU Dingguo, YU Yang, ZHANG Junli, GAO Qianrong. Epidemiological and etiological characteristics of hand-foot-mouth disease in Tongren City from 2018 to 2022[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2023, 44(12): 1898-1901. doi: 10.16835/j.cnki.1000-9817.2023.12.029

Citation:

PDF( 375 KB)

Epidemiological and etiological characteristics of hand-foot-mouth disease in Tongren City from 2018 to 2022

doi: 10.16835/j.cnki.1000-9817.2023.12.029

WU Dingguo^{1, 2},
YU Yang¹,
ZHANG Junli¹,
GAO Qianrong^{1
,
,}

1.
Tongren Disease Control and Prevention Center, Tongren (554300), Guizhou Province, China

Received Date: 2023-05-15
Rev Recd Date: 2023-10-09

Available Online: 2023-12-26

Publish Date: 2023-12-25

Abstract

Abstract

Objective To analyze the epidemiological and etiological characteristics of hand-foot-mouth disease (HFMD) in Tongren City during 2018 to 2022, so as to provide the reference for HFMD effective prevention and control. Methods Monitoring data on HFMD in Tongren City from 2018 to 2022 was collected from National Infectious Disease Reporting Information Management System. Descriptive epidemiological method was conducted on the data analysis. Results A total of 14 376 cases of HFMD were reported in Tongren City during 2018 to 2022, the average annual incidence rate of HFMD was 89.43/100 000. Totally 47 severe cases were reported, accounting for 0.33% of the total cases. The incidence rates of HFMD were generally declining trend during 2018 to 2022 (124.68/100 000, 95.37/100 000, 78.50/100 000, 61.63/100 000, 87.80/100 000) (χ_trend²=393.05, P < 0.01), mainly occurred during April to July (48.13%), among children under 5 years old (95.72%). During 2018 to 2022, a total of 967 laboratory diagnosed cases reported in different years, regions, age groups showed significant differences in pathogen composition ratio (χ²=169.62, 456.65, 167.96, P < 0.05). From 2018 to 2022, the dominant pathogen of HFMD was constantly changing. Other enteroviruses were the dominant epidemic strains in 2018 and 2022 (33.04%, 37.62%), CoxA 6 was the dominant epidemic strain in 2019 to 2020 (68.75%, 50.78%), and CoxA16 was the dominant epidemic strain in 2021(43.30%).In 2018, one case was infected with CoxA16 and EV71.The difference of pathogen composition ratio varied in different years (χ²=169.62, P < 0.01). Conclusions The prevalence of HFMD in Tongren City has showed a declining trend during 2018 to 2022, and the dominant strain of HFMD has changed in recent years. The pathogen monitoring of HFMD should be strengthened to timely grasp the distribution and changes of pathogens, so as to provide a basis for the precise prevention and control of HFMD.
- Hand, foot and mouth disease,
- Incidence,
- Epidemiologic studies,
- Child

FullText(HTML)

References(18)

References

[1]	LI Y, CHANG Z R, WU P, et al. Emerging enteroviruses causing hand, foot and mouth disease, China, 2010-2016[J]. Emerg Infect Dis, 2018, 24(10): 1902-1906. doi: 10.3201/eid2410.171953
[2]	XIE C, WEN H, YANG W, et al. Trend analysis and forecast of daily reported incidence of hand, foot and mouth disease in Hubei, China by prophet model[J]. Sci Rep, 2021, 11(1): 1445. doi: 10.1038/s41598-021-81100-2
[3]	王猛, 孙丽敏, 刘洋, 等. 重症手足口病危险因素分析[J]. 泰山医学院学报, 2019, 40(10): 796-797. https://www.cnki.com.cn/Article/CJFDTOTAL-TSYX201910033.htm WANG M, SUN L M, LIU Y, et al. Analysis of risk factors for severe hand, foot and mouth disease[J]. J Taishan Med Coll, 2019, 40(10): 796-797. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-TSYX201910033.htm
[4]	邵海枫, 杜国明, 陈海明, 等. 2017—2018年张家港市学校手足口病聚集性疫情流行病学和病原学特征分析[J]. 医学动物防制, 2021, 37(3): 280-283. https://www.cnki.com.cn/Article/CJFDTOTAL-YXDZ202103019.htm SHAO H F, DU G M, CHEN H M, et al. Epidemiological characteristics and etiology of clustering hand-foot-mouth disease in schools of Zhangjiagang from 2017 to 2018[J]. J Med Pest Control, 2021, 37(3): 280-283. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-YXDZ202103019.htm
[5]	张静, 李秀惠, 李丽, 等. 手足口病病原学和流行病学研究进展[J]. 中华流行病学杂志, 2022, 43(5): 771-783. https://www.cnki.com.cn/Article/CJFDTOTAL-YLZB202010127.htm ZHANG J, LI X H, LI L, et al. Etiology and epidemiology of hand, foot and mouth disease in China[J]. Chin J Epidemiol, 2022, 43(5): 771-783. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-YLZB202010127.htm
[6]	中华人民共和国国家卫生健康委员会印发《手足口病诊疗指南(2018年版)》[EB/OL]. (2018-05-15)[2023-12-03]. http://www.nhc.gov.cn/yzygj/s3594q/201805/5db274d8697a41ea84e88eedd8bf8f63.shtml. National Health Commission of the PRC issued the Guidelines for the diagnosis and treatment of hand, foot and mouth disease (2018 version)[EB/OL]. (2018-05-15)[2023-12-03]. http://www.nhc.gov.cn/yzygj/s3594q/201805/5db274d8697a41ea84e88eedd8bf8f63.shtml. (in Chinese)
[7]	中华人民共和国国家卫生和计划生育委员会. 手足口病诊断: WS 588―2018[J]. 中国病毒病杂志, 2018, 8(6): 427-433. https://www.cnki.com.cn/Article/CJFDTOTAL-HJKB202402018.htm National Health and Family Planning Commission of the PRC. Diagnosis for hand, food and mouth disease: WS 588-2018[J]. Chin J Viral Dis, 2018, 8(6): 427-433. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-HJKB202402018.htm
[8]	张静. 2008—2017年中国手足口病流行趋势和病原变化动态数列分析[J]. 中华流行病学杂志, 2019, 40(2): 147-154. ZHANG J. Trend of epidemics and variation of pathogens of hand, foot and mouth disease in China: a dynamic series analysis, 2008- 2017[J]. Chin J Epidemiol, 2019, 40(2): 147-154. (in Chinese)
[9]	文艳, 杨小蓉, 陈华. 2012—2021年绵阳市手足口病流行病学及病原学特征分析[J]. 医学动物防制, 2023, 39(4): 371-378. https://www.cnki.com.cn/Article/CJFDTOTAL-YXDZ202304015.htm WEN Y, YANG X R, CHEN H. Analysis of epidemiological and etiological characteristics of hand-foot-mouth disease in Mianyang from 2012 to 2021[J]. J Med Pest Control, 2023, 28(2): 185-190. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-YXDZ202304015.htm
[10]	赵玉峰, 姜栋栋, 井飞. 2017—2021年亳州市手足口病病例及病原学特征分析[J]. 华南预防医学, 2022, 48(10): 1227-1229, 1233. https://www.cnki.com.cn/Article/CJFDTOTAL-GDWF202210015.htm ZHAO Y F, JIANG D D, JING F, et al. Etiological characteristics of hand, foot and mouth disease in Bozhou City from 2017 to 2021[J]. South Chin J Prev Med, 2022, 48(10): 1227-1229, 1233. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-GDWF202210015.htm
[11]	杨溪, 曹亿会, 寸建萍, 等. 2015—2019年云南省手足口病流行及病原学特征分析[J]. 职业卫生与病伤, 2022, 37(5): 278-282. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYWB202205003.htm YANG X, CAO Y H, CUN J P, et al. Epidemiological and etiological characteristics of hand-foot-mouth disease in Yunnan Province from 2015 to 2019[J]. J Occup Health Dam, 2022, 37(5): 278-282. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZYWB202205003.htm
[12]	蒋佳洁, 潘杰. 2009—2018年资阳市手足口病流行病学及病原学特征分析[J]. 现代预防医学, 2022, 47(11): 1945-1949. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF202011008.htm JIANG J J, PAN J. Epidemiological characteristics and pathogenic characteristics of hand-foot-mouth disease in Ziyang, 2009-2018[J]. Mod Prev Med, 2022, 47(11): 1945-1949. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF202011008.htm
[13]	李冬冬, 汪鹏. 2011—2020年武汉市汉阳区手足口病流行特征及流行趋势分析[J]. 实用预防医学, 2023, 30(1): 98-100. https://www.cnki.com.cn/Article/CJFDTOTAL-SYYY202301025.htm LI D D, WANG P. Epidemiological characteristics and trends of hand-foot-mouth disease in Hanyang of Wuhan City from 2011 to 2020[J]. Pract Prev Med, 2013, 30(1): 98-100. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-SYYY202301025.htm
[14]	王佳欣. 学前儿童生活习惯的影响因素及培养策略[J]. 林区教学, 2019, 35(2): 115-117. https://www.cnki.com.cn/Article/CJFDTOTAL-LQXJ201902048.htm WANG J X. Factors affecting preschool children's living habits and countermeasures[J]. Teach For Reg, 2019, 35(2): 115-117. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-LQXJ201902048.htm
[15]	李法锦, 王丹, 郭军, 等. 贵州省2008—2015年手足口病病原学监测分析[J]. 中国疫苗和免疫, 2017, 23(4): 445-449. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGJM201704020.htm LI F J, WANG D, GUO J, et al. Virologic surveillance of hand, foot and mouth disease in Guizhou Province, 2008-2015[J]. Chin J Vacc Immun, 2017, 23(4): 445-449. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZGJM201704020.htm
[16]	张钟, 郑亚明, 姜黎黎, 等. 我国2015—2016年哨点监测手足口病病原学和并发症分析[J]. 中华流行病学杂志, 2019, 40(6): 627-632. ZHANG Z, ZHENG Y M, JIANG L L, et al. Review on the etiology and complications of hand, foot and mouth disease, using data from the national sentinel surveillance program, in China, 2015-2016[J]. Chin J Epidemiol, 2019, 40(6): 627-632. (in Chinese)
[17]	周春丽, 黄婷, 梁家芝. 2009—2018年南宁市手足口病流行病学特征分析[J]. 职业与健康, 2020, 36(8): 1079-1081, 1086. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJK202008020.htm ZHOU C L, HUANG T, LIANG J Z. Epidemiological analysis of hand-foot-mouth disease in Nanning City from 2009 to 2018[J]. Occup Health, 2020, 36(8): 1079-1081, 1086. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJK202008020.htm
[18]	刘殿菊. 天津市滨海新区接种手足口病疫苗前后流行病学特征对照分析[J]. 医学信息, 2019, 32(12): 133-135. https://www.cnki.com.cn/Article/CJFDTOTAL-YXXX201912043.htm LIU D J. Comparative analysis of epidemiological characteristics before and after inoculation of hand-foot-mouth disease vaccine in Binhai New Area of Tianjin[J]. Med Inform, 2019, 32(12): 133-135. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-YXXX201912043.htm