Relationship between serum free fatty acid/body mass index and metabolic syndrome among pupils in Yanbian Area

Objective To understand the relationship between serum free fatty acid / body mass index and metabolic syndrome (MS),and their combination effects on the risk of suffering MS among Han and Korean pupils in Yanbian area,and to provide a reference for screening the high-risk adolescents of MS in the early stage.Methods A cluster sampling method was used to select a total of 5 747 elementary school students (2 011 of Korean-Chinese and 3 736 of Han nationality) from 5 primary schools of Yanbian area from 15-18 July,2012 to 16-21 July,2013.The data about their height,weight,circumference (WC),SBP and DBP,serum triglyceride (TG),high-density lipoprotein cholesterol (HDL-C),glucose (FBG),free fatty acid (FFA) were collected.Results After adjustment for sex and age,the covariance analysis showed that the level of FFA in group with MS and in normal group among Han pupils was (22.72±2.72) and (21.09±2.60)iμmol/L,respectively,and those were (23.49±1.64) and (21.95± 1.63) μmol/L among Korean pupils,respectively;the levels of BMI in group with MS and in normal group were (25.68±3.58) and (16.98-±2.89) kg/m2 among Han pupils and those were (23.1 1±3.63) and (17.86±3.05) kg/m2 among Korean pupils,respectively.The levels of FFA and BMI in group with MS were higher than those in normal group(P<0.01).The prevalence of MS was progressively higher with the level of FFA and BMI (P<0.01) among Han and Korean pupils.The risk of MS in the upper quartile of FFA was 2.693 times as much as that in the lower quartile among Han pupils,and that was 12.132 times among Korean pupils;the risk of MS in overweight and obesity of BMI was 19.646 and 223.666 times as much as that in normal group among Han pupils,and that was 4.860 and 19.204 times among Korean pupils.The risk of MS was obviously increased in group with FFA≥P75 combined with overweight and obesity (Han:OR=172.524,95%CI=60.288-493.705;Korean:OR =79.188,95%CI=35.728-175.513),and that was obviously higher than that in group with FFA≥P75 combined with BMI normal and that in group with FFA