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内蒙古在校大学生体质量指数与肠道菌群宏基因组浓度的关联

徐欣蕊 王新雨 张婧 耿艺昆 边浩东 吴迎旭 刘艳超

徐欣蕊, 王新雨, 张婧, 耿艺昆, 边浩东, 吴迎旭, 刘艳超. 内蒙古在校大学生体质量指数与肠道菌群宏基因组浓度的关联[J]. 中国学校卫生, 2021, 42(1): 106-108. doi: 10.16835/j.cnki.1000-9817.2021.01.025
引用本文: 徐欣蕊, 王新雨, 张婧, 耿艺昆, 边浩东, 吴迎旭, 刘艳超. 内蒙古在校大学生体质量指数与肠道菌群宏基因组浓度的关联[J]. 中国学校卫生, 2021, 42(1): 106-108. doi: 10.16835/j.cnki.1000-9817.2021.01.025
XU Xinrui, WANG Xinyu, ZHANG Jing, GENG Yikun, BIAN Haodong, WU Yingxu, LIU Yanchao. Correlation between BMI and metagenomics concentration of gut microbiota of college students in Inner Mongolia[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(1): 106-108. doi: 10.16835/j.cnki.1000-9817.2021.01.025
Citation: XU Xinrui, WANG Xinyu, ZHANG Jing, GENG Yikun, BIAN Haodong, WU Yingxu, LIU Yanchao. Correlation between BMI and metagenomics concentration of gut microbiota of college students in Inner Mongolia[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(1): 106-108. doi: 10.16835/j.cnki.1000-9817.2021.01.025

内蒙古在校大学生体质量指数与肠道菌群宏基因组浓度的关联

doi: 10.16835/j.cnki.1000-9817.2021.01.025
基金项目: 

内蒙古医科大学“三位一体”大学生创新创业培育项目 SWYT2018027

详细信息
    作者简介:

    徐欣蕊(1998-),女,内蒙古赤峰人,在读本科

    通讯作者:

    刘艳超,E-mail:liuyanchao.hi@163.com

  • 中图分类号: R 446 R 723.14

Correlation between BMI and metagenomics concentration of gut microbiota of college students in Inner Mongolia

  • 摘要:   目的  探索内蒙古地区在校大学生体质量指数(BMI)与肠道菌群的关联性,为揭示肠道菌群与肥胖之间的关联性提供参考依据。  方法  以内蒙古医科大学为试点,通过招募方式共收集88名志愿者。测量研究对象的身高和体重,并收集粪便样本。提取干粪便样本中的细菌宏基因组,并检测干粪便细菌宏基因组质量浓度(μg/μL)。统计分析BMI与肠道菌群宏基因组质量浓度的相关性,并比较不同BMI组的肠道菌群宏基因组质量浓度差异。  结果  大学生BMI与肠道菌群的宏基因组质量浓度呈负相关(r=-0.27,P < 0.05)。不同BMI大学生的肠道菌群宏基因组质量浓度差异有统计学意义(F=3.62,P < 0.05)。分性别分析,女生中,不同BMI的肠道菌群宏基因组质量浓度差异有统计学意义(F=1.87,P < 0.05),两两比较正常组与超重组、正常组与肥胖组差异均有统计学意义(P值均 < 0.05);男生中,不同BMI的肠道菌群宏基因组质量浓度差异无统计学意义(F=0.60,P>0.05)。  结论  内蒙古地区在校大学生BMI与其肠道菌群具有关联性,超重及肥胖人群肠道菌群宏基因组质量浓度显著降低。
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出版历程
  • 收稿日期:  2020-06-17
  • 修回日期:  2020-08-10
  • 网络出版日期:  2021-04-01
  • 刊出日期:  2021-01-25

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