Research progress in mechanisms of neuromuscular system regulation in adolescent idiopathic scoliosis
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摘要: 青少年特发性脊柱侧凸(adolescent idiopathic scoliosis,AIS)是青少年群体中较为常见的脊柱健康问题,其发病机制尚不明确,但对儿童青少年的心、智、形影响极大。文章从神经生理学角度出发,通过讨论AIS神经系统的解剖形态、生理功能和肌肉代谢神经调控的国内外研究进展,分析脊柱运动的神经—肌肉系统的动态平衡调控机制,认为由于中枢神经系统对脊柱神经—肌肉的协同控制失衡,从而产生一系列脊柱的动力学代偿反应,导致AIS的产生和/或发展,为解决青少年脊柱健康问题的教育干预方法提供理论指导。Abstract: Adolescent idiopathic scoliosis (AIS) is a relatively common spinal health problem in the adolescents, whose pathogenesis remains unclear. AIS substantially affects the mind, intellect and body shape in children and adolescents. From a neurophysiological perspective, this article discusses progress in domestic and international research on the anatomical morphology, physiological function and neuromodulation of muscle metabolism in the nervous system in AIS, and analyses the dynamic balance in regulatory mechanisms of the neuromuscular system affecting spinal movement, which argues that an imbalance between the synergistic control of the central nervous system and the spinal neuromuscular system results in a series of kinetic compensatory responses of the spine, thus leading to AIS generation and/or development. This article is aimed at providing theoretical guidance for educational intervention approaches to address adolescent spinal health problems.
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Key words:
- Scoliosis /
- Central nervous system /
- Research /
- Adolescent
1) 利益冲突声明 所有作者声明无利益冲突。 -
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