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青春期女生尿液中大豆异黄酮代谢物与性发育的关系

章涵 赵玉霞

章涵, 赵玉霞. 青春期女生尿液中大豆异黄酮代谢物与性发育的关系[J]. 中国学校卫生, 2021, 42(7): 1080-1082. doi: 10.16835/j.cnki.1000-9817.2021.07.028
引用本文: 章涵, 赵玉霞. 青春期女生尿液中大豆异黄酮代谢物与性发育的关系[J]. 中国学校卫生, 2021, 42(7): 1080-1082. doi: 10.16835/j.cnki.1000-9817.2021.07.028
ZHANG Han, ZHAO Yuxia. Relationship between soy isoflavone metabolites in urine and sexual development of adolescent girls[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(7): 1080-1082. doi: 10.16835/j.cnki.1000-9817.2021.07.028
Citation: ZHANG Han, ZHAO Yuxia. Relationship between soy isoflavone metabolites in urine and sexual development of adolescent girls[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(7): 1080-1082. doi: 10.16835/j.cnki.1000-9817.2021.07.028

青春期女生尿液中大豆异黄酮代谢物与性发育的关系

doi: 10.16835/j.cnki.1000-9817.2021.07.028
基金项目: 

河南省高等学校重点科研项目资助计划 21A330005

详细信息
    作者简介:

    章涵(1978-),男,河南淮滨人,硕士,副教授,主要从事青少年卫生教研工作

    通讯作者:

    赵玉霞,E-mail:zhaoyuxia888@126.com

  • 中图分类号: R446  R173

Relationship between soy isoflavone metabolites in urine and sexual development of adolescent girls

  • 摘要:   目的  探讨尿液中大豆异黄酮代谢物与青春期女生性发育的关系, 为女生青春期发育影响因素研究提供参考依据。  方法  在信阳市1所小学随机选择符合纳入标准的50名五年级女生为研究对象, 进行性发育评价及尿液中大豆异黄酮代谢物的测定。尿液中大豆异黄酮代谢物的测定运用超高速液相色谱-串联质谱分析法(UPLC-MS/MS)。  结果  不同性发育组女生(发育提前、发育正常和发育延迟)的染料木黄酮水平差异有统计学意义(F=3.53, P < 0.05), 发育提前组尿液染料木黄酮水平较高; 已来潮组和未来潮组染料木黄酮水平差异有统计学意义(t=2.16, P < 0.05), 已来潮组尿液染料木黄酮水平较高。  结论  尿液染料木黄酮水平高可能与青春期女生性发育提前有关。
  • 表  1  不同组别女生大豆异黄酮代谢物水平比较(x±s,μmol·mol-1)

    Table  1.   Comparison of soybean isoflavone metabolites levels in different pubertal development groups of girls (x±s, μmol·mol-1)

    组别 选项 人数 统计值 染料木黄酮 黄豆苷元
    性发育 提前 8 186.7±24.1 315.6±33.4
    正常 35 171.8±22.8 308.4±31.1
    延迟 7 155.3±21.6 305.8±31.3
    F 3.53 0.22
    P < 0.05 > 0.05
    月经初潮 已来潮 6 213.4±22.5 311.4±32.2
    未来潮 44 166.3±21.7 308.9±31.9
    t 2.16 0.08
    P < 0.05 > 0.05
    下载: 导出CSV
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出版历程
  • 收稿日期:  2021-01-04
  • 修回日期:  2021-04-13
  • 网络出版日期:  2021-07-23
  • 刊出日期:  2021-07-25

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