Association between Mediterranean diet scores and dental caries among children and adolescents with neurodevelopmental disorders

XIONG Wenjuan; SU Yuanyuan; LIU Zhao; HUANG Xiaoqing; QU Zhiyi; CUI Shanshan

doi:10.16835/j.cnki.1000-9817.2025037

Volume 46 Issue 2

Feb. 2025

Turn off MathJax

Article Contents

Article Navigation > CHINESE JOURNAL OF SCHOOL HEALTH > 2025 > 46(2): 172-176

XIONG Wenjuan, SU Yuanyuan, LIU Zhao, HUANG Xiaoqing, QU Zhiyi, CUI Shanshan. Association between Mediterranean diet scores and dental caries among children and adolescents with neurodevelopmental disorders[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2025, 46(2): 172-176. doi: 10.16835/j.cnki.1000-9817.2025037

Citation:

XIONG Wenjuan, SU Yuanyuan, LIU Zhao, HUANG Xiaoqing, QU Zhiyi, CUI Shanshan. Association between Mediterranean diet scores and dental caries among children and adolescents with neurodevelopmental disorders[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2025, 46(2): 172-176. doi: 10.16835/j.cnki.1000-9817.2025037

Citation:

XIONG Wenjuan, SU Yuanyuan, LIU Zhao, HUANG Xiaoqing, QU Zhiyi, CUI Shanshan. Association between Mediterranean diet scores and dental caries among children and adolescents with neurodevelopmental disorders[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2025, 46(2): 172-176. doi: 10.16835/j.cnki.1000-9817.2025037

PDF( 419 KB)

Association between Mediterranean diet scores and dental caries among children and adolescents with neurodevelopmental disorders

doi: 10.16835/j.cnki.1000-9817.2025037

1.
School of Public Health, Tianjin Medical University, Tianjin (300070), China

Received Date: 2024-08-02
Rev Recd Date: 2024-09-23

Available Online: 2025-03-05

Publish Date: 2025-02-25

Abstract

Abstract

Objective To explore the association between mediterranean diet (MD) patterns and dental caries among children and adolescents with neurodevelopmental disorders (NDD), so as to provide a basis for developing scientific anti-caries strategies related to diet. Methods From December 2021 to June 2024, a questionnaire survey, a three-day 24-hour dietary review survey, oral health examination, physical development measurement and Childhood Autism Rating Scale (CARS) evaluation were conducted involving 147 children and adolescents aged 2-22 years with NDD from nine special education schools and rehabilitation institutions in Tianjin. Group comparisons were carried out using the Mann-Whitney U test, Chi-square test, or Fisher's exact probability method. The correlation between dietary quality and dental caries was analyzed by adopting multiple linear regression analysis and restricted cubic spline. Results There were 46 children and adolescents (31.3%) in the non-dental caries group and 101 children and adolescents (68.7%) in the dental caries group. The number of decayed missing and filled teeth (dmft) was 2.0 (4.0), and the MD score was 4.0 (2.0) points. There were 62 children and adolescents (42.2%) in the low MD scores group and 85 children and adolescents (57.8%) in the high MD scores group. There was no significant difference in MD scores between NDD children in the non-dental caries group and those in the dental caries group [non-dental caries group: 4.0(2.0), dental caries group: 4.0(2.0), Z=-0.14, P>0.05]. The MD scores and dmft exhibited increasing and then decreasing trend (P_total=0.02, P_non-lineary=0.04). Children and adolescents with NDD in the MD high scores group had a lower number of dmft than those in the MD low scores group (β=-2.00, 95%CI=-3.39 to -0.62, P < 0.05). However, in children and adolescents with NDD and CARS scores ≥30, the above association was insignificant (β=-0.63, 95%CI=-0.29-0.15, P>0.05). Conclusions Children and adolescents with NDD who have dietary patterns similar to the Mediterranean diet, are found to have fewer dental caries, and this is observed among those with no or mild symptoms of autism spectrum disorder.
- Neurodevelopmental disorders,
- Diet, Mediterranean,
- Dental caries,
- Regression analysis,
- Child,
- Adolescent

FullText(HTML)

References(28)

References

[1]	RAI A, SUNDAS S, DHAKAL N, et al. Assessment of dental caries based on ICDAS and WHO criteria: a comparative study[J]. Int J Paediatr Dent, 2024, 34(1): 77-84. doi: 10.1111/ipd.13099
[2]	WHO. Global oral health status report: towards universal health coverage for oral health by 2030[EB/OL]. (2022-11-18)[2024-07-10]. https://www.who.int/publications/i/item/9789240061484.
[3]	SHERRIFF A, STEWART R, MACPHERSON L M D, et al. Child oral health and preventive dental service access among children with intellectual disabilities, autism and other educational additional support needs: a population-based record linkage cohort study[J]. Commun Dent Oral Epidemiol, 2023, 51(3): 494-502. doi: 10.1111/cdoe.12805
[4]	AUGIMERI G, CAPARELLO G, CAPUTO I, et al. Mediterranean diet: a potential player in the link between oral microbiome and oral diseases[J]. J Oral Microbiol, 2024, 16(1): 2329474. doi: 10.1080/20002297.2024.2329474
[5]	KIANI A K, MEDORI M C, BONETTI G, et al. Modern vision of the mediterranean diet[J]. J Prev Med Hyg, 2022, 63(2 Suppl 3): E36-E43.
[6]	MARQUÉS-MARTÍNEZ L, PÉREZ-BERMEJO M, LAIRÖN-PER-IS A R, et al. Association between the severity of dental caries and the degree of adherence to the Mediterranean diet in the pediatric population[J]. Nutrients, 2022, 14(17): 3622. doi: 10.3390/nu14173622
[7]	中华人民共和国教育部等六部门关于开展2019年全国学生体质与健康调研及国家学生体质健康标准抽查复核工作的通知[EB/OL]. (2019-07-12)[2024-07-10]. http://www.moe.gov.cn/srcsite/A17/moe_943/moe_946/201907/t20190724_392121.html.
[8]	WHO. Oral health survey: basic methods[M]. 5th ed. Switzerland: WHO Press, 2013: 1-125.
[9]	KIM S, PARK C Y. Validity of interviewer-administered 24-h dietary recalls in older Korean women: a pilot study[J]. Nutrients, 2023, 15(7): 1757. doi: 10.3390/nu15071757
[10]	YIN W, LÖF M, CHEN R, et al. Mediterranean diet and depression: a population-based cohort study[J]. Int J Behav Nutr Phys Act, 2021, 18(1): 153. doi: 10.1186/s12966-021-01227-3
[11]	SCHOPLER E, REICHLER R J, DEVELLIS R F, et al. Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS)[J]. J Autism Dev Disord, 1980, 10(1): 91-103. doi: 10.1007/BF02408436
[12]	马聪, 吕玲玲, 张慧婷. 孤独症谱系障碍儿童核心症状与血清微量元素的关联[J]. 中国妇幼保健, 2024, 39(21): 4148-4151. MA C, LV L L, ZHANG H T. The association between core symptoms and serum trace elements in children with autism spectrum disorder[J]. Matern Child Health Care China, 2024, 39(21): 4148-4151. (in Chinese)
[13]	杨耀菊. 广西残疾人康复研究中心残障儿童口腔健康状况调查与分析[D]. 百色: 右江民族医学院, 2023. YANG Y J. Investigation and analysis of oral health status of disabled children in Guangxi Rehabilitation Research Center for the Disabled[D]. Baise: Youjiang Medical University for Nationalities, 2023. (in Chinese)
[14]	张冰洁. 福州市部分残疾儿童龋病状况调查[D]. 福州: 福建医科大学, 2016. ZHANG B J. Caries status of disabled children in Fuzhou[D]. Fuzhou: Fujian Medical University, 2016. (in Chinese)
[15]	邬东, 肖旭阳, 谭兵兵, 等. 2021年成都市1 553名7~12岁儿童体质指数与龋病的相关性[J]. 卫生研究, 2023, 52(3): 509-513. WU D, XIAO X Y, TAN B B, et al. The correlation between body mass index and dental caries in 1 553 children aged 7-12 years old in Chengdu in 2021[J]. J Hyg Res, 2023, 52(3): 509-513. (in Chinese)
[16]	杨文华, 成思源, 黄晶. 儿童龋齿伴幽门螺杆菌感染状况调查[J]. 中国妇幼保健, 2021, 36(4): 890-892. YANG W H, CHENG S Y, HUANG J. An investigation of children with dental caries accompanied by Helicobacter pylori infection[J]. Matern Child Health Care China, 2021, 36(4): 890-892. (in Chinese)
[17]	MARTIGNON S, RONCALLI A G, ALVAREZ E, et al. Risk factors for dental caries in Latin American and Caribbean countries[J]. Braz Oral Res, 2021, 35(Suppl 1): e053. doi: 10.1590/1807-3107bor-2021.vol35.0053
[18]	ESIN K, BALL-AKGÖL B, SÖZLÜ S, et al. Association between dental caries and adherence to the mediterranean diet, dietary intake, and body mass index in children[J]. BMC Oral Health, 2024, 24(1): 297. doi: 10.1186/s12903-024-04020-3
[19]	MELWANI-SADHWANI R, ALONSO-AGUSTÍN E R, SAGOLS-RUIZ A, et al. Analysis of oral health among ADHD-affected and non-ADHD children in Gran Canaria[J]. Healthcare (Basel), 2024, 12(7): 779.
[20]	KAISER S J, MUTTERS N T, BLESSING B, et al. Natural isothiocyanates express antimicrobial activity against developing and mature biofilms of pseudomonas aeruginosa[J]. Fitoterapia, 2017, 119: 57-63. doi: 10.1016/j.fitote.2017.04.006
[21]	COCCO F, CARTA G, CAGETTI M G, et al. The caries preventive effect of 1-year use of low-dose xylitol chewing gum. A randomized placebo-controlled clinical trial in high-caries-risk adults[J]. Clin Oral Investig, 2017, 21(9): 2733-2740. doi: 10.1007/s00784-017-2075-5
[22]	GUO Y, LI Z, CHEN F, et al. Polyphenols in oral health: homeostasis maintenance, disease prevention, and therapeutic applications[J]. Nutrients, 2023, 15(20): 4384. doi: 10.3390/nu15204384
[23]	KAYE E A, SOHN W, GARCIA R I. The healthy eating index and coronal dental caries in US adults: national health and nutrition examination survey 2011-2014[J]. J Am Dent Assoc, 2020, 151(2): 78-86. doi: 10.1016/j.adaj.2019.09.009
[24]	LIANG X, LU H, LIN P, et al. Association between dietary fiber to carbohydrate ratio and risk of dental caries in diabetic patients: an analysis of the national health and nutrition examination survey 2015-2020[J]. Front Nutr, 2024(11): 1440306.
[25]	AVERY J A, INGEHOLM J E, WOHLTJEN S, et al. Neural correlates of taste reactivity in autism spectrum disorder[J]. Neuroimage Clin, 2018, 19: 38-46. doi: 10.1016/j.nicl.2018.04.008
[26]	WANG X, MA Z, LEI M, et al. Association between early childhood caries and diet quality among Chinese children aged 2-5 years[J]. Front Public Health, 2022(10): 974419.
[27]	ZERMAN N, ZOTTI F, CHIRUMBOLO S, et al. Insights on dental care management and prevention in children with autism spectrum disorder (ASD). What is new?[J]. Front Oral Health, 2022(3): 998831.
[28]	BABU N V, ROY A. Comparative analysis of the status of dental caries and selected salivary electrolytes in children with autism[J]. Int J Clin Pediatr Dent, 2022, 15(Suppl 2): S242-S246.