Prevalence of latent tuberculosis infection among freshmen in middle schools and their willingness of preventive treatment in Yunyan District of Guiyang

PENG Xiaowei; ZHANG Jiangping; LUO Peng; CHEN Siyin; XU Mengqun; WANG Qun

doi:10.16835/j.cnki.1000-9817.2025007

Volume 46 Issue 1

Jan. 2025

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PENG Xiaowei, ZHANG Jiangping, LUO Peng, CHEN Siyin, XU Mengqun, WANG Qun. Prevalence of latent tuberculosis infection among freshmen in middle schools and their willingness of preventive treatment in Yunyan District of Guiyang[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2025, 46(1): 129-133. doi: 10.16835/j.cnki.1000-9817.2025007

Citation:

PENG Xiaowei, ZHANG Jiangping, LUO Peng, CHEN Siyin, XU Mengqun, WANG Qun. Prevalence of latent tuberculosis infection among freshmen in middle schools and their willingness of preventive treatment in Yunyan District of Guiyang[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2025, 46(1): 129-133. doi: 10.16835/j.cnki.1000-9817.2025007

Citation:

PENG Xiaowei, ZHANG Jiangping, LUO Peng, CHEN Siyin, XU Mengqun, WANG Qun. Prevalence of latent tuberculosis infection among freshmen in middle schools and their willingness of preventive treatment in Yunyan District of Guiyang[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2025, 46(1): 129-133. doi: 10.16835/j.cnki.1000-9817.2025007

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Prevalence of latent tuberculosis infection among freshmen in middle schools and their willingness of preventive treatment in Yunyan District of Guiyang

doi: 10.16835/j.cnki.1000-9817.2025007

1.
School of Public Health and Health Services, Guizhou Medical University/Key Laboratory of Environmental Pollution and Disease Surveillance, Ministry of Education, Guiyang(561113), Guizhou Province, China

Received Date: 2024-08-28
Rev Recd Date: 2024-11-13

Available Online: 2025-01-25

Publish Date: 2025-01-25

Abstract

Abstract

Objective To investigate the status of latent tuberculosis infection(LTBI)among freshmen in middle schools and their willingness of preventive treatment in Yunyan District of Guiyang, so as to provide a reference for the prevention and control of tuberculosis in schools. Methods The tuberculin skin test (TST) and X-ray scans were used to screen the TB infection of 13 915 freshmen in middle schools in Yunyan District of Guiyang in 2023, and a questionnaire survey on the willingness of accepting tuberculosis preventive treatment was conducted to LTBI patients. The χ² test and Fisher exact probability was conducted for the comparison of the rates among the groups. Results Among the freshmen screened, the detection rate of LTBI was 3.29%. There were statistically significant difference in LTBI rates among freshmen of different genders (boys: 2.87%, girls: 3.81%), age groups (12-15 years old: 3.31%, 16-17 years old: 3.92%, 18-20 years old: 1.91%), and school stages (junior high school: 3.52%, ordinary high school: 5.96%, vocational high school: 2.29%)(χ²=9.59, 13.08, 54.30, P < 0.01). A total of 356 LTBI freshmen completed questionnaire survey, and 299(83.99%) were willing to accept tuberculosis preventive treatment, but the actual number of LIBI freshman who underwent preventive treatment was zero. Those LTBI who had received Bacille Calmette-Guérin(BCG) vaccine(86.97%) was higher in the reporting rates of being willing to accept preventive treatment than that of LTBI who had not received BCG vaccine(75.79%), the differences were statistically significant(χ²=6.48, P < 0.05). The main reasons for refusing preventive treatment was worry about adverse drug reactions(80.70%), social acceptance and the support of social institutions were needed most(85.96%). Conclusion The LTBI rate among freshmen in Yunyan District of GuiYang is higher. Although the freshmen with LTBI have a higher willingness to accept preventive treatment, however, no one has undergone preventive treatment. Corresponding measures need to be taken for improving the preventive treatment rate of LIBI freshmen.
- Tuberculosis,
- Infection,
- Protecitve agents,
- Attitude,
- Students

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志谢: 感谢贵阳市疾病预防控制中心及贵阳市云岩区疾病预防控制中心对本研究的帮助和支持。

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