A case-control study of dietary behavior and central precocious puberty among children

CHEN Xue; AN Wenhua; XIONG Zhaoying; FAN Yiwei; LIU Hongxiu; LI Ruizhen

doi:10.16835/j.cnki.1000-9817.2024345

Volume 45 Issue 11

Nov. 2024

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Article Navigation > CHINESE JOURNAL OF SCHOOL HEALTH > 2024 > 45(11): 1629-1633

CHEN Xue, AN Wenhua, XIONG Zhaoying, FAN Yiwei, LIU Hongxiu, LI Ruizhen. A case-control study of dietary behavior and central precocious puberty among children[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2024, 45(11): 1629-1633. doi: 10.16835/j.cnki.1000-9817.2024345

Citation:

CHEN Xue, AN Wenhua, XIONG Zhaoying, FAN Yiwei, LIU Hongxiu, LI Ruizhen. A case-control study of dietary behavior and central precocious puberty among children[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2024, 45(11): 1629-1633. doi: 10.16835/j.cnki.1000-9817.2024345

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A case-control study of dietary behavior and central precocious puberty among children

doi: 10.16835/j.cnki.1000-9817.2024345

CHEN Xue^{1, 2},
AN Wenhua³,
XIONG Zhaoying³,
FAN Yiwei^{1, 3},
LIU Hongxiu³,
LI Ruizhen^{2
,
,}

1.
School of Medicine, Wuhan University of Science and Technology, Wuhan (430081), Hubei Province, China

Received Date: 2024-07-22
Rev Recd Date: 2024-09-13

Available Online: 2024-12-10

Publish Date: 2024-11-15

Abstract

Abstract

Objective To explore the relationship between dietary behavior, dietary frequency and central precocious puberty (CPP) among children in Wuhan, so as to provide a scientific basis for elucidating the possible and related dietary factors leading to precocious puberty. Methods From February to December 2023, 100 children with CPP and 100 healthy children were collected in Wuhan Children's Hospital for a case-control study. Questionnaires and interviews were used to collect demographic information, child lifestyle, as well as dietary behavior and dietary frequency in the past six months. Conditional Logistic regression model was used to analyze the relationship of children's dietary behavior and dietary frequency with CPP. Results No associations were found between three dietary behavior, including emotional eating, restrictive eating, and external eating, with CPP at baseline (P>0.05). In the association analysis of dietary frequency and CPP, the risk of CPP was higher in those who consumed red meat >5 times/week (OR=1.93, 95%CI=1.01-3.68), carbonated beverages ≥4 times/month (OR=2.70, 95%CI=1.03-7.08), fruit juices ≥4 times/month (OR=2.31, 95%CI=1.02-5.25), and nutritional supplementation (OR=2.77, 95%CI=1.47-5.22), whereas the risk of CPP was lower in those who consumed nuts ≥4 times/month (OR=0.21, 95%CI=0.08-0.57) (P < 0.05). Conclusion Consumption of higher amounts of red meat, high frequency of carbonated and juice-based sugary drinks, and nutrient supplementation may be contributing factors to the development of CPP, whereas regular consumption of nuts is less likely to be associated with the development of CPP.
- Food habits,
- Puberty, precocious,
- Case-control Studies,
- Regression analysis,
- Child

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References(27)

References

[1]	LATRONICO A C, BRITO V N, CAREL J C. Causes, diagnosis, and treatment of central precocious puberty[J]. Lancet Diabetes Endocrinol, 2016, 4(3): 265-274. doi: 10.1016/S2213-8587(15)00380-0
[2]	中华医学会儿科学分会内分泌遗传代谢学组, 中华儿科杂志编辑委员会. 中枢性性早熟诊断与治疗共识(2015)[J]. 中华儿科杂志, 2015, 53(6): 412-418. Endocrinology Genetics and Metabolism Group, Pediatrics Branch of Chinese Medical as sociation, Editorial Committee of the Chinese Journal of Pediatrics. Consensus on the diagnosis and treatment of central precocious puberty (2015)[J]. Chin J Pediatr, 2015, 53(6): 412-418. (in Chinese)
[3]	朱铭强, 傅君芬, 梁黎, 等. 中国儿童青少年性发育现状研究[J]. 浙江大学学报(医学版), 2013, 42(4): 396-402, 410. ZHU M Q, FU J F, LIANG L, et al. Epidemiologic study on current pubertal development in Chinese school-aged children[J]. J Zhejiang Univ (Med Sci), 2013, 42(4): 396-402, 410. (in Chinese)
[4]	ECKERT-LIND C, BUSCH A S, PETERSEN J H, et al. Worldwide secular trends in age at pubertal onset assessed by breast development among girls[J]. JAMA Pediatr, 2020, 174(4): e195881. doi: 10.1001/jamapediatrics.2019.5881
[5]	中华医学会儿科学分会内分泌遗传代谢学组, 中华儿科杂志编辑委员会. 中枢性性早熟诊断与治疗专家共识(2022)[J]. 中华儿科杂志, 2023, 61(1): 16-22. Endocrine Genetics and Metabolism Group, Pediatrics Branch of Chinese Medical Association, Editorial Committee of the Chinese Journal of Pediatrics. Expert consensus on the diagnosis and treatment of central precocious puberty(2022)[J]. Chin J Pediatr, 2023, 61(1): 16-22. (in Chinese)
[6]	AGUIRRE R S, EUGSTER E A. Central precocious puberty: from genetics to treatment[J]. Best Pract Res Clin Endocrinol Metab, 2018, 32(4): 343-354. doi: 10.1016/j.beem.2018.05.008
[7]	YOO J H. Effects of early menarche on physical and psychosocial hea-lth problems in adolescent girls and adult women[J]. Korean J Pediatr, 2016, 59(9): 355-361. doi: 10.3345/kjp.2016.59.9.355
[8]	HOYT L T, NIU L, PACHUCKI M C, et al. Timing of puberty in boys and girls: implications for population health[J]. SSM Popul Health, 2020, 10: 100549. doi: 10.1016/j.ssmph.2020.100549
[9]	MAIONE L, BOUVATTIER C, KAISER U B. Central precocious puberty: recent advances in understanding the aetiology and in the clinical approach[J]. Clin Endocrinol (Oxf), 2021, 95(4): 542-555. doi: 10.1111/cen.14475
[10]	杨博, 刘琴, 刘舒丹, 等. 青春发动时相提前影响因素的系统评价[J]. 中国循证医学杂志, 2018, 18(12): 1337-1351. YANG B, LIU Q, LIU S D, et al. Relevant factors of early puberty timing: a systematic review[J]. Chin J Evid Based Med, 2018, 18(12): 1337-1351. (in Chinese)
[11]	严雪梅, 诸宏伟, 丁周志. 80例儿童中枢性性早熟特征及其相关危险因素分析[J]. 新疆医科大学学报, 2021, 44(10): 1176-1181. YAN X M, ZHU H W, DING Z Z. Analysis of the characteristics and related risk factors of children with central precocious puberty[J]. J Xinjiang Med Univ, 2021, 44(10): 1176-1181. (in Chinese)
[12]	赵艳. 儿童版荷兰饮食行为量表的修订[D]. 武汉: 武汉体育学院, 2018. ZHAO Y. Revised application of the Dutch Eating Behavior Questionnaire Child-version[D]. Wuhan: Wuhan Sport University, 2018. (in Chinese)
[13]	JANSEN E C, MARIN C, MORA-PLAZAS M, et al. Higher childhood red meat intake frequency is associated with earlier age at menarche[J]. J Nutr, 2015, 146(4): 792-798.
[14]	GU Q, WU Y, FENG Z, et al. Dietary pattern and precocious puberty risk in Chinese girls: a case-control study[J]. Nutr J, 2024, 23(1): 14. doi: 10.1186/s12937-024-00916-6
[15]	SHI L, JIANG Z, ZHANG L. Childhood obesity and central precocious puberty[J]. Front Endocrinol (Lausanne), 2022, 13: 1056871. doi: 10.3389/fendo.2022.1056871
[16]	LIU M, CAO B, LUO Q, et al. The critical BMI hypothesis for puberty initiation and the gender prevalence difference: evidence from an epidemiological survey in Beijing, China[J]. Front Endocrinol (Lausanne), 2022, 13: 1009133. doi: 10.3389/fendo.2022.1009133
[17]	NIEUWENHUIS D, PUJOL-GUALDO N, ARNOLDUSSEN I, et al. Adipokines: a gear shift in puberty[J]. Obes Rev, 2020, 21(6): e13005. doi: 10.1111/obr.13005
[18]	CALCATERRA V, MAGENES V C, HRUBY C, et al. Links between childhood obesity, high-fat diet, and central precocious puberty[J]. Children (Basel), 2023, 10(2): 241.
[19]	LOPEZ-RODRIGUEZ D, FRANSSEN D, HEGER S, et al. Endocrine-disrupting chemicals and their effects on puberty[J]. Best Pract Res Clin Endocrinol Metab, 2021, 35(5): 101579. doi: 10.1016/j.beem.2021.101579
[20]	朱薇, 孟庆杰, 孙雅军. 儿童中枢性性早熟的特征及其发病的影响因素分析[J]. 临床医学, 2022, 42(8): 34-36. ZHU W, MENG Q J, SUN Y J. Analysis on the characteristics and influencing factors of central precocious puberty in children[J]. Clin Med, 2022, 42(8): 34-36. (in Chinese)
[21]	VALSAMAKIS G, ARAPAKI A, BALAFOUTAS D, et al. Diet-induced hypothalamic inflammation, phoenixin, and subsequent precocious puberty[J]. Nutrients, 2021, 13(10): 3460. doi: 10.3390/nu13103460
[22]	HUANG X Y, CHEN J X, REN Y, et al. Postnatal feeding with high-fat combined with high-glucose diet induces precocious puberty in Sprague-Dawley rat pups[J]. Biochem Biophys Res Commun, 2024, 693: 149199. doi: 10.1016/j.bbrc.2023.149199
[23]	王玲, 李晶晶, 杨淼, 等. 中小学生坚果摄入行为及其与肥胖的关联[J]. 中国儿童保健杂志, 2014, 22(11): 1178-1182. WANG L, LI J J, YANG M, et al. Nut consumption and its association with child obesity in Chinese school children[J]. Chin J Child Health Care, 2014, 22(11): 1178-1182. (in Chinese)
[24]	BES-RASTROLLO M, SABATÉ J, GÓMEZ-GRACIA E, et al. Nut consumption and weight gain in a Mediterranean cohort: the SUN study[J]. Obesity(Silver Spring), 2007, 15(1): 107-116.
[25]	CHENG G, BUYKEN A E, SHI L, et al. Beyond overweight: nutrition as an important lifestyle factor influencing timing of puberty[J]. Nutr Rev, 2012, 70(3): 133-152. doi: 10.1111/j.1753-4887.2011.00461.x
[26]	KOO M M, ROHAN T E, JAIN M, et al. A cohort study of dietary fibre intake and menarche[J]. Public Health Nutr, 2002, 5(2): 353-360. doi: 10.1079/PHN2002261
[27]	吴春红, 朱乔波, 邵东良, 等. 膳食对学龄期女童性早熟的影响[J]. 中国妇幼健康研究, 2021, 32(6): 847-852. WU C H, ZHU Q B, SHAO D L, et al. Influence of diet on precocious puberty in school-age girls[J]. Chin Matern Child Health Res, 2021, 32(6): 847-852. (in Chinese)