Volume 44 Issue 4
Apr.  2023
Turn off MathJax
Article Contents
CHEN Jinxia, CAO Qiaoan, MA Chunhua, SU Xiaoyun. Effects of a ketogenic diet combined with resistance training on body composition and glucolipid metabolism in the obese and female college students[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2023, 44(4): 512-516. doi: 10.16835/j.cnki.1000-9817.2023.04.008
Citation: CHEN Jinxia, CAO Qiaoan, MA Chunhua, SU Xiaoyun. Effects of a ketogenic diet combined with resistance training on body composition and glucolipid metabolism in the obese and female college students[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2023, 44(4): 512-516. doi: 10.16835/j.cnki.1000-9817.2023.04.008

Effects of a ketogenic diet combined with resistance training on body composition and glucolipid metabolism in the obese and female college students

doi: 10.16835/j.cnki.1000-9817.2023.04.008
  • Received Date: 2022-11-17
  • Rev Recd Date: 2023-01-12
  • Available Online: 2023-04-26
  • Publish Date: 2023-04-25
  •   Objective  To investigate the effects of a ketogenic diet (KD) alone and in combination with resistance training (KD+RT) on body composition and glucolipid metabolism of obese and female college students, and to provide a theoretical basis for the application of KD+RT in obese patients.  Methods  Totally 45 obese and female college students in Wuyi University were recruited and randomly divided into KD group (n=23) and KD+RT group (n=22) in September 2021. After received training for 4 weeks, the changes of body composition and glucose and lipid metabolism of obese and female college students were compared before and after intervention.  Results  Both a 4-week KD and KD+RT led to decreases in weight, BMI, body fat mass, body fat percentage, waist to hip ratio, visceral fat area of obese female college students (t=16.19, 16.21, 12.42, 7.99, 2.10, 6.37; 18.82, 18.02, 17.80, 10.72, 3.41, 7.59, P < 0.01). The change of muscle mass was decreased in KD group(t=4.12, P < 0.01), but there was no statistically significant difference in KD+RT group(P>0.05). Both a 4-week KD and KD+RT significantly reduced the levels of the fasting blood glucose, fasting insulin, glycosylated hemoglobin and triglyceride (TG) of obese female college students (t=10.15, 8.94, 6.94, 7.63; 9.23, 12.75, 9.85, 9.09, P < 0.01), and increased the high-density lipoprotein (HDL) level(t=-7.36, -5.22, P < 0.01). However, only KD+RT group had a significant decrease in the level of LDL (t=5.27, P < 0.01), and there was no significant change in the level of TC both groups (P>0.05). After the intervention, there was no statistically significant difference between the KD+RT group compared to the KD group (P>0.05), except for a significant decrease in triacylglycerol (t=2.51, P < 0.05).  Conclusion  Both a short-term KD and KD+RT show beneficial changes in body composition and glucolipid metabolism in obese female college students. However, the KD+RT is superior to a KD in maintaining muscle mass and reducing the effects of lipid metabolism.
  • loading
  • [1]
    周鸣. 有氧运动对肥胖大学生部分心血管疾病危险因素的影响[D]. 南昌: 华东交通大学, 2017.

    ZHOU M. Effects of aerobic exercise on part of cardiovascular disease risk factors for obesity college students[D]. Nanchang: East China Jiaotong University, 2017. (in Chinese)
    [2]
    CALCATERRA V, VERDUCI E, PASCUZZI M C, et al. Metabolic derangement in pediatric patient with obesity: the role of ketogenic diet as therapeutic tool[J]. Nutrients, 2021, 13(8): 2805. doi: 10.3390/nu13082805
    [3]
    CASTELLANA M, CONTE E, CIGNARELLI A, et al. Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: a systematic review and Meta-analysis[J]. Rev Endocrinol Metab Disord, 2020, 21(1): 5-16. doi: 10.1007/s11154-019-09514-y
    [4]
    KRIEGER J W, SITREN H S, DANIELS M J, et al. Effects of variation in protein and carbohydrate intake on body mass and composition during energy restriction: a Meta-regression 1[J]. Am J Clin Nutr, 2006, 83(2): 260-274. doi: 10.1093/ajcn/83.2.260
    [5]
    李合, 随曾辉, 侯希贺, 等. 不同类型抗阻训练对男大学生体成分及骨密度的影响比较[J]. 中国学校卫生, 2019, 40(10): 1529-1532. doi: 10.16835/j.cnki.1000-9817.2019.10.025

    LI H, SUI Z H, HOU X H, et al. An empirical study on the changes of upper limb composition and BMD of male university students by different types of resistance training[J]. Chin J Sch Health, 2019, 40(10): 1529-1532. (in Chinese) doi: 10.16835/j.cnki.1000-9817.2019.10.025
    [6]
    DONNELLY J E, BLAIR S N, JAKICIC J M, et al. American College of Sports Medicine Position Stand. Appropriate physical activity intervention strategies for weight loss and prevention of weight regain for adults[J]. Med Sci Sports Exerc, 2009, 41(2): 459-471. doi: 10.1249/MSS.0b013e3181949333
    [7]
    王健, 马军, 王翔. 健康教育学[M]. 北京: 高等教育出版社, 2021: 265.

    WANG J, MA J, WANG X. Health Education[M]. Beijing: Higher Education Press, 2021: 265. (in Chinese)
    [8]
    李健, 白文佩, 江波, 等. 生酮饮食对超重/肥胖多囊卵巢综合征患者维生素D及糖脂代谢的影响[J]. 实用临床医药杂志, 2022, 26(4): 14-17, 32. https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL202204004.htm

    LI J, BAI W P, JIANG B, et al. Effects of ketogenic diet on vitamin D and glycolipid metabolism in overweight or obese patients with polycystic ovary syndrome[J]. J Chin Med Prac, 2022, 26(4): 14-17, 32. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-XYZL202204004.htm
    [9]
    孙长灏. 营养与食品卫生学[M]. 北京: 人民卫生出版社, 2017: 1-33.

    SUN C H. Nutrition and food hygiene[M]. Beijing: People's Medical Publishing House, 2017: 1-33. (in Chinese)
    [10]
    杨辉, 张片红, 江波, 等. 生酮饮食及限能平衡饮食对超重及肥胖者人体成分及生化指标的影响[J]. 营养学报, 2018, 40(4): 403-405. https://www.cnki.com.cn/Article/CJFDTOTAL-YYXX201804025.htm

    YANG H, ZHANG P H, JIANG B, et al. Effects of ketogenic diet and calorie restrict diet on body composition and biochemical parameters of overweight and obese adults[J]. Acta Nutr Sinica, 2018, 40(4): 403-405. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-YYXX201804025.htm
    [11]
    PAOLI A, CENCI L, POMPEI P, et al. Effects of two months of very low carbohydrate ketogenic diet on body composition, muscle stren-gth, muscle area, and blood parameters in competitive natural body builders[J]. Nutrients, 2021, 13(2): 374. doi: 10.3390/nu13020374
    [12]
    YUAN X, WANG J, YANG S, et al. Effect of the ketogenic diet on glycemic control, insulin resistance, and lipid metabolism in patients with T2DM: a systematic review and Meta-analysis[J]. Nutr Diabetes, 2020, 10(1): 38. doi: 10.1038/s41387-020-00142-z
    [13]
    于冬妮, 王丽娟, 程博, 等. 利拉鲁肽对成年肥胖2型糖尿病患者身体成分和肌力的影响[J]. 中华内科杂志, 2021, 60(11): 982-986.

    YU D N, WANG L J, CHENG B, et al. The effects of liraglutide on body composition and muscle strength in adult obese patients with type 2 diabetes mellitus[J]. Chin J Inter Med, 2021, 60(11): 982-986. (in Chinese)
    [14]
    VOLEK J S, SHARMAN M J, LOVE D M, et al. Body composition and hormonal responses to a carbohydrate-restricted diet[J]. Metabolism, 2002, 51(7): 864-870. doi: 10.1053/meta.2002.32037
    [15]
    ASHTARY-LARKY D, BAGHERI R, ASBAGHI O, et al. Effects of resistance training combined with a ketogenic diet on body composition: a systematic review and Meta-analysis[J]. Crit Rev Food Sci Nutr, 2022, 62(21): 5717-5732. doi: 10.1080/10408398.2021.1890689
    [16]
    高睿琦, 唐成林, 曹净, 等. 电针对去神经支配骨骼肌萎缩大鼠PI3K/Akt/mTOR信号通路的影响[J]. 中国康复医学杂志, 2018, 33(1): 15-21. https://www.cnki.com.cn/Article/CJFDTOTAL-ZGKF201801004.htm

    GAO R Q, TANG C L, CAO J, et al. Effects of electroacupuncture on PI3K/Akt/mTOR singaling pathway in denervated skeletal muscle atrophy in rats[J]. Chin J Rehabil Med, 2018, 33(1): 15-21. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZGKF201801004.htm
    [17]
    LAYMAN D K, EVANS E, BAUM J I, et al. Dietary protein and exercise have additive effects on body composition during weight loss in adult women[J]. J Nutr, 2005, 135(8): 1903-1910.
    [18]
    FLECK S J, KRAEMER W J. Designing resistance training programs[M]. Champaign: Human Kinetics, 2004: 1-10.
    [19]
    MICHALCZYK M M, KLONEK G, MASZCZYK A, et al. The effects of a low calorie ketogenic diet on glycaemic control variables in hyperinsulinemic overweight/obese females[J]. Nutrients, 2020, 12(6): 1854.
    [20]
    VALENZANO A, POLITO R, TRIMIGNO V, et al. Effects of very low calorie ketogenic diet on the orexinergic system, visceral adipose tissue, and ROS production[J]. Antioxidants (Basel), 2019, 8(12): 643.
    [21]
    肖艳梅, 薛琨, 党正一, 等. 极低热量生酮饮食对超重/肥胖人群减重干预有效性和安全性的Meta分析[J]. 中国循证医学杂志, 2022, 22(4): 403-410. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZXZ202204005.htm

    XIAO Y M, XUE K, DANG Z Y, et al. Efficacy and safety of a very low-calorie ketogenic diet (VLCKD) in patients with overweight and obesity: a Meta-analysis[J]. Chin J Evid-Based Med, 2022, 22(4): 403-410. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZZXZ202204005.htm
    [22]
    COLICA C, MERRA G, GASBARRINI A, et al. Efficacy and safety of very-low-calorie ketogenic diet: a double blind randomized crossover study[J]. Eur Rev Med Pharmacol Sci, 2017, 21(9): 2274-2289.
    [23]
    LANGFORT J, PLOUG T, IHLEMANN J, et al. Stimulation of hormone-sensitive lipase activity by contractions in rat skeletal muscle[J]. Biochem J, 2000, 351(Pt 1): 207-214.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Tables(2)

    Article Metrics

    Article views (379) PDF downloads(40) Cited by()
    Proportional views

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return