Relationship between urinary metals and lung function in college students

RONG Suying; LIU Jiajia; YANG Wenqi; ZENG Hao; ZHANG Lei; FANG Bo; XU Houjun; WANG Qian

doi:10.16835/j.cnki.1000-9817.2022.02.029

Volume 43 Issue 2

Feb. 2022

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RONG Suying, LIU Jiajia, YANG Wenqi, ZENG Hao, ZHANG Lei, FANG Bo, XU Houjun, WANG Qian. Relationship between urinary metals and lung function in college students[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2022, 43(2): 288-291. doi: 10.16835/j.cnki.1000-9817.2022.02.029

Citation:

RONG Suying, LIU Jiajia, YANG Wenqi, ZENG Hao, ZHANG Lei, FANG Bo, XU Houjun, WANG Qian. Relationship between urinary metals and lung function in college students[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2022, 43(2): 288-291. doi: 10.16835/j.cnki.1000-9817.2022.02.029

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Relationship between urinary metals and lung function in college students

doi: 10.16835/j.cnki.1000-9817.2022.02.029

RONG Suying¹,
LIU Jiajia²,
YANG Wenqi³,
ZENG Hao²,
ZHANG Lei^{2, 4},
FANG Bo^{2, 5},
XU Houjun²,
WANG Qian^{2
,
,}

1.
Department of Clinical Medicine, Tangshan Vocational and Technical College, Tangshan (063000), Hebei Province, China

Received Date: 2021-08-31
Rev Recd Date: 2021-12-29

Available Online: 2022-02-24

Publish Date: 2022-02-25

Abstract

Abstract

Objective To explore the association between urinary metals and lung function among college students, and to provide a theoretical basis for related research on metal exposure and lung function injury. Methods A total of 45 healthy college students were recruited from North China University of Science and Technology in Caofeidian between 2017-2018. During the four seasons, information was obtained from questionnaires and physical examinations, lung function parameters were assessed, including FVC, FEV1, PEF, FEV1/FVC and FEF_25-75, and morning urine samples were collected simultaneously. The urinary levels of 15 metals were measured by inductively coupled plasma mass spectrometry (ICP/MS); a Kruskal-Wallis H test was used to compare differences in urinary metals during the four seasons; and a mixed effect model was used to assess correlations between urinary metals and lung function. Results There were significant differences in the levels of urinary chromium, iron, nickel, copper, zinc, arsenic, selenium, selenium, molybdenum, cadmium, antimony and lead from 15 metals over the four seasons (H=9.79-20.61, P < 0.05). The differences observed in five lung function parameters over the four seasons were statistically significant (F=61.72, 45.30, 47.61, 25.47, 35.13, P < 0.05). The linear mixed effect model analysis showed that urinary concentrations of vanadium, manganese, iron, cobalt, nickel and antimony were negatively correlated with FEV1(B=0.202, 0.192, 0.181, 0.154, 0.131, 0.283); urinary concentrations of aluminum, vanadium, manganese, iron, cobalt, nickel, zinc, cadmium, and antimony were negatively correlated with FVC (B=0.252, 0.290, 0.292, 0.271, 0.201, 0.180, 0.171, 0.163, 0.381); urinary concentrations of manganese and antimony were negatively correlated with PEF (B=0.291, 0.354)(P < 0.05). Conclusion The increase of multiple metal concentrations among college students was related to lung function decline, the long-term metal exposure might lead to lung function damage. So environmental metal pollution should be controlled.
- Urine,
- Metals,
- Lung,
- Linear models,
- Students

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References(20)

References

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