Left visual field superiority of children with autism spectrum disorder

TIAN Li; HAN Yu; DAI Wei; SU Yuanyuan; ZHANG Xin; GAO Lei

doi:10.16835/j.cnki.1000-9817.2021.12.030

Volume 42 Issue 12

Dec. 2021

Turn off MathJax

Article Contents

Article Navigation > CHINESE JOURNAL OF SCHOOL HEALTH > 2021 > 42(12): 1883-1887

TIAN Li, HAN Yu, DAI Wei, SU Yuanyuan, ZHANG Xin, GAO Lei. Left visual field superiority of children with autism spectrum disorder[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(12): 1883-1887. doi: 10.16835/j.cnki.1000-9817.2021.12.030

Citation:

TIAN Li, HAN Yu, DAI Wei, SU Yuanyuan, ZHANG Xin, GAO Lei. Left visual field superiority of children with autism spectrum disorder[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(12): 1883-1887. doi: 10.16835/j.cnki.1000-9817.2021.12.030

Citation:

PDF( 414 KB)

Left visual field superiority of children with autism spectrum disorder

doi: 10.16835/j.cnki.1000-9817.2021.12.030

TIAN Li¹,
HAN Yu²,
DAI Wei²,
SU Yuanyuan²,
ZHANG Xin²,
GAO Lei^{2
,
,}

1.
The Department of Brain Electrical Function, Tianjin Anding Hospital, Tianjin (300222), China

Received Date: 2021-09-03
Rev Recd Date: 2021-10-20

Available Online: 2021-12-23

Publish Date: 2021-12-25

Abstract

Abstract

Objective To explore the impairments of the left visual field (LVF) superiority among children with autism spectrum disorder (ASD), for further understanding of the attentional mechanism of social disturbance in ASD. Methods The mixed design for repeated measured data was used. The case group was consisted of 105 ASD children enrolled from the rehabilitation agencies in Tianjin from Sept. 2016 to Dec. 2019; and 105 typically developed children were enrolled from Tianjin as the control group by matching the chronological age and gender distribution. The preferential looking paradigm was used to explore the LVF superiority by eye-tracking system. Fixation count (FC), total fixation duration (TFD) and the proportion of left hemiface were analyzed by the Mixed-design ANOVA, in which the main effect of "group", visual field (left vs. right) and gender of the faces was evaluated in addition to the interactions. Results All the participants in both the ASD group and TD group completed the experiments. For the whole face in LVF or RVF, the main effect of group showed the statistical significance on both FC and TFD [FC: F_{(1, 206)}=26.27, P < 0.01; TFD: F_{(1, 206)}=51.23, P < 0.01]. The interaction of group×visual field on FC also was statistically significant [F_{(1, 206)}=4.619, P=0.03], and the case group showed the difference between LVF and RVF (0.33±0.02, 0.54±0.03, P < 0.01) by further simple effect analysis, none of the rest was statistically significant. Both the left hemiface of FC & TFD showed the main effect of group [FC: F_{(1, 206)}=13.77, P < 0.01;TFD: F_{(1, 206)}=12.89, P < 0.01] and interaction of group×visual field [FC: F_{(1, 206)}=36.99, P < 0.01;TFD: F_{(1, 206)}=38.62, P < 0.01), similarly, there was higher left hemiface proportion of both FC & TFD in RVF than that in LVF (FC: 0.36±0.03, 0.56±0.03, P < 0.01; TFD: 0.36±0.03, 0.57±0.03, P < 0.01). Conclusion LVF superiority is not presented among children with ASD in this study, while the fixation in RVF remained relatively unaffected. The finding indicates the involvement of the fusiform face area of right hemisphere in the pathogenesis of ASD in addition to the weak central coherence account.
- Autistic disorder,
- Visual fields,
- Analysis of variance,
- Child

FullText(HTML)

References(27)

References

[1]	LORD C, ELSABBAGH M, BAIRD G, et al. Autism spectrum disorder[J]. Lancet, 2018, 392(10146): 508-520. doi: 10.1016/S0140-6736(18)31129-2
[2]	BEHRMANN M, AVIDAN G, LEONARD G L, et al. Configural processing in autism and its relationship to face processing[J]. Neuropsychologia, 2006, 44(1): 110-129. doi: 10.1016/j.neuropsychologia.2005.04.002
[3]	CHAWARSKA K, VOLKMAR F, KLIN A. Limited attentional bias for faces in toddlers with autism spectrum disorders[J]. Arch Gen Psychiatry, 2010, 67(2): 178-185. doi: 10.1001/archgenpsychiatry.2009.194
[4]	FRAZIER T W, STRAUSS M, KLINGEMIER E W, et al. A meta-analysis of gaze differences to social and nonsocial information between individuals with and without autism[J]. J Am Acad Child Adolesc Psychiatry, 2017, 56(7): 546-555. doi: 10.1016/j.jaac.2017.05.005
[5]	JUNG W, KANG J G, JEON H, et al. Neural correlates of the eye dominance effect in human face perception: the left-visual-field superiority for faces revisited[J]. Soc Cogn Affect Neurosci, 2017, 12(8): 1342-1350. doi: 10.1093/scan/nsx056
[6]	HAUSMANN M, INNES B R, BIRCH Y K, et al. Laterality and (in)visibility in emotional face perception: manipulations in spatial frequency content[J]. Emotion, 2021, 21(1): 175-183. doi: 10.1037/emo0000648
[7]	PASCALIS O, DE HAAN M, NELSON C A. Is face processing species-specific during the first year of life?[J]. Science, 2002, 296(5571): 1321-1323. doi: 10.1126/science.1070223
[8]	SCOTT L S, MONESSON A. Experience-dependent neural specialization during infancy[J]. Neuropsychologia, 2010, 48(6): 1857-1861. doi: 10.1016/j.neuropsychologia.2010.02.008
[9]	DUNDAS E M, BEST C A, MINSHEW N J, et al. A lack of left visual field bias when individuals with autism process faces[J]. J Autism Dev Disord, 2012, 42(6): 1104-1111. doi: 10.1007/s10803-011-1354-2
[10]	DUNDAS E, GASTGEB H, STRAUSS M S. Left visual field biases when infants process faces: a comparison of infants at high-and low-risk for autism spectrum disorder[J]. J Autism Dev Disord, 2012, 42(12): 2659-2668. doi: 10.1007/s10803-012-1523-y
[11]	ASHWIN C, WHEELWRIGHT S, BARON-COHEN S. Laterality biases to chimeric faces in Asperger syndrome: what is 'right' about face-processing?[J]. J Autism Dev Disord, 2005, 35(2): 183-196. doi: 10.1007/s10803-004-1997-3
[12]	AMERICAN PSYCHIATRIC ASSOCIATION. Diagnostic and Statistical Manual of Mental Disorders (DSM-5)[M]. 5 ed. Washington, DC: American Psychiatric Association Publishing, 2013: 50-54.
[13]	白露, 马慧, 黄宇霞, 等. 中国情绪图片系统的编制: 在46名中国大学生中的试用[J]. 中国心理卫生杂志, 2005, 19(11): 719-722. doi: 10.3321/j.issn:1000-6729.2005.11.001 BAI L, MA H, HUANG Y X, et al. The development of native chinese affective picture system: a pretest in 46 college students[J]. Chin Ment Health J, 2005, 19(11): 719-722. doi: 10.3321/j.issn:1000-6729.2005.11.001
[14]	龚中心, 郭迪. 学前和初小儿童智能筛查: 图片词汇测试法[J]. 心理学报, 1984(4): 392-401. GONG Z X, GUO D. An intelligence screening test for preschool and primary school children: picture vocabulary test[J]. Acta Psychol Sinica, 1984(4): 392-401.
[15]	郭璇, 朱远来, 焦小燕, 等. 汉语版、哈萨克语版皮博迪图片词汇测验第四版的效度与信度[J]. 中国心理卫生杂志, 2019, 33(11): 845-850. GUO X, ZHU Y L, JIAO X Y, et al. Validity and reliability of the Chinese and kazakh versions of the peabody picture vocabulary test-four edition in preschool children[J]. Chin Ment Health J, 2019, 33(11): 845-850.
[16]	SCHOPLER E, REICHLER R J, DEVELLIS R F, et al. Toward objective classification of childhood autism: Childhood Autism Rating Scale (CARS)[J]. J Autism Dev Disord, 1980, 10(1): 91-103. doi: 10.1007/BF02408436
[17]	卢建平, 杨志伟, 舒明耀, 等. 儿童孤独症量表评定的信度、效度分析[J]. 中国现代医学杂志, 2004, 14(13): 119-23. doi: 10.3969/j.issn.1005-8982.2004.13.037 LU J P, YONG Z W, SHU M Y, et al. Reliability, validity analysis of the childhood autism rating scale[J]. Chin J Modern Med, 2004, 14(13): 119-123. doi: 10.3969/j.issn.1005-8982.2004.13.037
[18]	BUNDY D A, SILVA N D, HORTON S, et al. Child and adolescent health and development[M]. 3 ed. Washington (DC): The World Bank, 2017: 79-98.
[19]	CHITA-TEGMARK M. Social attention in ASD: a review and meta-analysis of eye-tracking studies[J]. Res Dev Disabil, 2016, 48: 79-93. doi: 10.1016/j.ridd.2015.10.011
[20]	沈周玲, 柏石倩, 范静怡. 4~7岁孤独症谱系障碍儿童视觉整体与局部加工研究及启示[J]. 心理学进展, 2019, 9(6): 1033-1040. SHEN Z L, BAI S Q, FAN J Y, et al. A study on the local-global visual processing in 4-7 years old children with autism spectrum disorder and the implications for the following research[J]. Adv Psychol, 2019, 9(6): 1033-1040.
[21]	SASSON N J, TURNER-BROWN L M, HOLTZCLAW T N, et al. Children with autism demonstrate circumscribed attention during passive viewing of complex social and nonsocial picture arrays[J]. Autism Res, 2008, 1(1): 31-42. doi: 10.1002/aur.4
[22]	HAPPÉ F, FRITH U. The weak coherence account: detail-focused cognitive style in autism spectrum disorders[J]. J Autism Dev Disord, 2006, 36(1): 5-25. doi: 10.1007/s10803-005-0039-0
[23]	PASCALIS O, DE MARTIN DE VIVIÉS X, ANZURES G, et al. Development of face processing[J]. Wiley Interdiscip Rev Cogn Sci, 2011, 2(6): 666-675. doi: 10.1002/wcs.146
[24]	ALJUHANAY A, MILNE E, BURT D M, et al. Asymmetry in face processing during childhood measured with chimeric faces[J]. Laterality, 2010, 15(4): 439-450. doi: 10.1080/13576500902972823
[25]	ABBOTT J D, WIJERATNE T, HUGHES A, et al. The influence of left and right hemisphere brain damage on configural and featural processing of affective faces[J]. Laterality, 2014, 19(4): 455-472. doi: 10.1080/1357650X.2013.862256
[26]	ICHIKAWA H, KANAZAWA S, YAMAGUCHI M K, et al. Infant brain activity while viewing facial movement of point-light displays as measured by near-infrared spectroscopy (NIRS)[J]. Neurosci Lett, 2010, 482(2): 90-94. doi: 10.1016/j.neulet.2010.06.086
[27]	PITCHER D, DILKS D D, SAXE R R, et al. Differential selectivity for dynamic versus static information in face-selective cortical regions[J]. Neuroimage, 2011, 56: 2356-2363. doi: 10.1016/j.neuroimage.2011.03.067