Analysis of serum 25-hydroxyvitamin D levels in children aged 0-6 years in Gansu Province

HUANG Lei; NAN Nan; LIU Aiping; YANG Xiaofang; LI Ling; ZHU Ying

doi:10.16835/j.cnki.1000-9817.2021.12.011

Volume 42 Issue 12

Dec. 2021

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HUANG Lei, NAN Nan, LIU Aiping, YANG Xiaofang, LI Ling, ZHU Ying. Analysis of serum 25-hydroxyvitamin D levels in children aged 0-6 years in Gansu Province[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(12): 1803-1806. doi: 10.16835/j.cnki.1000-9817.2021.12.011

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HUANG Lei, NAN Nan, LIU Aiping, YANG Xiaofang, LI Ling, ZHU Ying. Analysis of serum 25-hydroxyvitamin D levels in children aged 0-6 years in Gansu Province[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(12): 1803-1806. doi: 10.16835/j.cnki.1000-9817.2021.12.011

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Analysis of serum 25-hydroxyvitamin D levels in children aged 0-6 years in Gansu Province

doi: 10.16835/j.cnki.1000-9817.2021.12.011

1.
Child Health Care Section, Gansu Hospital of Maternal and Child Care, Lanzhou(730050), China

Received Date: 2021-07-21
Rev Recd Date: 2021-09-23

Available Online: 2021-12-23

Publish Date: 2021-12-25

Abstract

Abstract

Objective To analyze the status of serum 25-hydroxyvitamin D in children aged 0-6 years in Gansu Province, and to analyze the relationships between 25-(OH)D and age, seasonal characteristics and physical development, so as to provide a scientific reference for supplementing vitamin D for children in due time. Methods Stratified random cluster sampling method was used to select a total of 9 790 children aged 0-6 years from 6 cities and prefectures maternity and child health institutions in Gansu Province for health examination from January 2019 to December 2020. Serum 25-(OH)D concentration from 1 mL peripheral blood was tested by enzyme-linked immunoassay. Subjects were classified into overweight and normal figure groups based on weight for height. Results the serum 25-(OH)D level M(P₂₅, P₇₅) of the children aged 0-6 was 81.31(63.14, 95.86)nmol/L. The detection rate of 25-(OH)D deficiency and insufficiency was 45.11%. The serum 25-(OH)D level of children 4-6 years old was significantly lower than that of infants < 1 year old and children 1- < 4 years old, and the detection rate of 25-(OH)D deficiency and insufficiency was highest among 4-6 years old(χ²=83.67, P < 0.05). In winter the proportion of 25-(OH)D insufficiency and deficiency was highest (55.82%) (χ²=194.12, P < 0.01). For overweight children, the abnormal rate of 25-(OH)D (19.83%) was significantly higher in autumn (P < 0.01). Conclusion Children's vitamin D levels were associated with age, season and physical development. Vitamin D surveillance should be focused on ages less than 1 year old and above 4 years old, winter should be an important season. For overweight children, autumn should be the focus period for vitamin D deficiency prevention.
- Serum,
- Vitamin D,
- Nutritional status,
- Child

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References(17)

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