Association between sleep with C-reactive protein and insulin metabolism in adolescents

TANG Yuqing; LI Liwen; LYU Jiajun; CHEN Yiting; WANG Xiaobin; LI Shenghui

doi:10.16835/j.cnki.1000-9817.2021.06.005

Volume 42 Issue 6

Jun. 2021

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Article Navigation > CHINESE JOURNAL OF SCHOOL HEALTH > 2021 > 42(6): 819-823,828

TANG Yuqing, LI Liwen, LYU Jiajun, CHEN Yiting, WANG Xiaobin, LI Shenghui. Association between sleep with C-reactive protein and insulin metabolism in adolescents[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(6): 819-823,828. doi: 10.16835/j.cnki.1000-9817.2021.06.005

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TANG Yuqing, LI Liwen, LYU Jiajun, CHEN Yiting, WANG Xiaobin, LI Shenghui. Association between sleep with C-reactive protein and insulin metabolism in adolescents[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(6): 819-823,828. doi: 10.16835/j.cnki.1000-9817.2021.06.005

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Association between sleep with C-reactive protein and insulin metabolism in adolescents

doi: 10.16835/j.cnki.1000-9817.2021.06.005

1.
School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai(200025), China

Received Date: 2021-02-01
Rev Recd Date: 2021-05-20

Available Online: 2021-06-22

Publish Date: 2021-06-25

Abstract

Abstract

Objective To explore the relationship of sleep with C-reactive protein (CRP) abnormality and hyperinsulinemia in adolescents, and to provide reference for early prevention of metabolic disorders. Methods Based on the Chinese Metabolic Syndrome Cohort Study in Anhui Province, a total of 653 adolescents aged 12 to 19 were selected to examine the relationship between wakeup time, bedtime, sleep disordered breathing (SDB) and CRP abnormality as well as hyperinsulinemia. Results Later wakeup time (OR=1.68, 95%CI=1.03-2.75) was positively correlated with a higher risk of fasting hyperinsulinemia. Late bedtime (OR=1.96, 95%CI=1.29-2.99) was associated with 2 h postprandial hyperinsulinemia. Among those with high CRP concentration, late wakeup time and late bedtime were positely associated with hyperinsulinemia than those with normal CRP concentration; and the correlation between SDB and hyperinsulinemia was observed. Conclusion Later wakeup and late bedtime may be risk factors for hyperinsulinemia in adolescents. High concentrations of CRP may further increase the risk of hyperinsulinemia, a condition associated with sleep problems.Teenagers should get up and go to bed as early as possible.
- Sleep,
- C-reactive protein,
- Insulin,
- Regression analysis,
- Adolescent

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References(39)

References

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