Influence of birthweight and delivery mode on obesity among primary school students in Guangzhou

ZHANG Guangchuan; LIANG Jianping; YANG Lun; HUANG Weihao; LU Shuang; AO Liping; LI Zhanglong; YANG Yi; LIU Li

doi:10.16835/j.cnki.1000-9817.2021.02.029

Volume 42 Issue 2

Apr. 2021

Turn off MathJax

Article Contents

Article Navigation > CHINESE JOURNAL OF SCHOOL HEALTH > 2021 > 42(2): 277-281

ZHANG Guangchuan, LIANG Jianping, YANG Lun, HUANG Weihao, LU Shuang, AO Liping, LI Zhanglong, YANG Yi, LIU Li. Influence of birthweight and delivery mode on obesity among primary school students in Guangzhou[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(2): 277-281. doi: 10.16835/j.cnki.1000-9817.2021.02.029

Citation:

ZHANG Guangchuan, LIANG Jianping, YANG Lun, HUANG Weihao, LU Shuang, AO Liping, LI Zhanglong, YANG Yi, LIU Li. Influence of birthweight and delivery mode on obesity among primary school students in Guangzhou[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(2): 277-281. doi: 10.16835/j.cnki.1000-9817.2021.02.029

Citation:

ZHANG Guangchuan, LIANG Jianping, YANG Lun, HUANG Weihao, LU Shuang, AO Liping, LI Zhanglong, YANG Yi, LIU Li. Influence of birthweight and delivery mode on obesity among primary school students in Guangzhou[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2021, 42(2): 277-281. doi: 10.16835/j.cnki.1000-9817.2021.02.029

PDF( 383 KB)

Influence of birthweight and delivery mode on obesity among primary school students in Guangzhou

doi: 10.16835/j.cnki.1000-9817.2021.02.029

1.
School of Public Health, Guangdong Pharmaceutical University, Guangzhou(510310), China

Received Date: 2020-09-20
Rev Recd Date: 2020-11-05

Available Online: 2021-04-06

Publish Date: 2021-02-25

Abstract

Abstract

Objective To explore the influence of birthweight and delivery mode on overweight/obesity and abdominal obesity in primary school students, and to provide evidence for childhood obesity prevention. Methods After physical examination, questionnaire survey was conducted among 3 361 students and their parents from 3 primary schools in Guangzhou selected through stratified clustering sampling. Information about birthweight and delivery mode was collected. Logistic regression model was used to analyze the association of birthweight and delivery mode with overweight/obesity and abdominal obesity. The multiplicative interaction term and the Delta method was used to explore the potential interaction. Results The prevalence rate of overweight and obesity for primary school students was 21.33%, and the rate of abdominal obesity was 12.08%. Multivariate Logistic regression analysis showed that delivery by cesarean section was associated with 44% increased risk of overweight/obesity(OR=1.44, 95%CI=1.16-1.80), as compared to vaginal delivery. Higher birthweight was linked to increased risk of overweight/obesity(OR=1.62, 95%CI=1.09-2.42). There was no significant association of birth weight and delivery mode with abdominal obesity in multivariate analysis(P>0.05). Additionally, a positive additive interaction was seen between delivery mode and parental obesity for students' risk of overweight/obesity(RERI=0.33, 95%CI=0.02-0.65), as well as for the risk of abdominal obesity(RERI=0.39, 95%CI=0.12-0.65). Conclusion Cesarean section delivery and higher birthweight are linked to increased risk of overweight and obesity in primary school students. The synergistic effect of cesarean section and parental obesity may increase the risk of childhood obesity.
- Birth weight,
- Obesity,
- Parturition,
- Regression analysis,
- Students

FullText(HTML)

References(25)

References

[1]	LIANG Y J, HOU D Q, ZHAO X Y, et al. Childhood obesity affects adult metabolic syndrome and diabetes[J]. Endocrine, 2015, 50(1): 87-92. doi: 10.1007/s12020-015-0560-7
[2]	SUNG H, REBECCA L, LINDSEY A, et al. Global patterns in excess body weight and the associated cancer burden[J]. Cancer J Clin, 2019, 69(2): 88-112.
[3]	HALES C N, BARKER D J. The thrifty phenotype hypothesis[J]. Br Med Bull, 2001, 60(462): 5-20. http://bmb.oxfordjournals.org/content/60/1/5.full
[4]	罗碧莲, 桂曌环, 陈亚军. 广州市某社区2-6岁儿童超重肥胖与生命早期因素研究[J]. 中国学校卫生, 2019, 40(12): 1788-1790, 1795. https://www.cnki.com.cn/Article/CJFDTOTAL-XIWS201912010.htm LUO B L, GUI Z H, CHEN Y J. Relationship of obesity and early-life factors among 2-6 years old preschoolers in a community in Guangzhou[J]. Chin J Sch Health, 2019, 40(12): 1788-1790, 1795. https://www.cnki.com.cn/Article/CJFDTOTAL-XIWS201912010.htm
[5]	TIAN J Y, CHENG Q, SONG X M, et al. Birth weight and risk of type 2 diabetes, abdominal obesity and hypertension among Chinese adults[J]. Eur J Endocrinol, 2006, 155(4): 601-607. doi: 10.1530/eje.1.02265
[6]	DENG J R, TAN W Q, YANG S Y, et al. High birth weight and its interaction with physical activity influence the risk of obesity in early school-aged children[J]. World J Pediatr, 2020, 16(4): 385-392. doi: 10.1007/s12519-020-00336-6
[7]	程红, 陈芳芳, 叶佩玉, 等. 2013—2015年中国7城市6~17岁儿童青少年心血管代谢危险因素的流行特征[J]. 中华预防医学杂志, 2018, 52(11): 1130-1135. doi: 10.3760/cma.j.issn.0253-9624.2018.11.007 CHEN H, CHEN F F, YE P Y. Characteristics of cardiometabolic risk factors of children and adolescents aged 6-17 years in seven cities in China from 2013 to 2015[J]. Chin J Prev Med, 2018, 52(11): 1130-1135. doi: 10.3760/cma.j.issn.0253-9624.2018.11.007
[8]	沈晓明, 王卫平. 儿科学[M]. 9版. 北京: 人民卫生出版社, 2018. SHEN X M, WANG W P. Pediatrics. 9th edition. [M]. Beijing: People's Medical Publishing House, 2018.
[9]	中华人民共和国国家卫生和计划生育委员会. 学龄儿童青少年超重与肥胖筛查WS/T 586—2018[S]. 北京: 中国标准出版社, 2018. National Health and Family Planning Commission of the People's Republic of China. Screening for overweight and obesity among school-age children and adolescents WS/T 586-2018[S]. Beijing: China Stardards Press, 2018.
[10]	葛均波, 徐永健, 王辰. 内科学[M]. 北京: 人民卫生出版社, 2018. GE J B, XU Y J, WANG C. Internal medicine[M]. Beijing: People's Medical Publishing House, 2018.
[11]	中华医学会儿科学分会内分泌遗传代谢学组, 中华医学会儿组, 科学分会心血管学组, 等. 中国儿童青少年代谢综合征定义和防治建议[J]. 中华儿科杂志, 2012, 50(6): 420-422. doi: 10.3760/cma.j.issn.0578-1310.2012.06.005 Subspecialty Group of Endocrinologic, Hereditary and Metabolic Diseases, Society of Pediatrics, et al. The definition of metabolic syndrome and prophylaxis and treatment proposal in Chinese children and adolescents[J]. Chin J Pediatr, 2012, 50(6): 420-422. doi: 10.3760/cma.j.issn.0578-1310.2012.06.005
[12]	张云婷, 马生霞, 陈畅, 等. 中国儿童青少年身体活动指南[J]. 中国循证儿科杂志, 2017, 12(6): 401-409. doi: 10.3969/j.issn.1673-5501.2017.06.001 ZHANG Y T, MA S X, CHEN C, et al. Physical activity guidelines for Chinese children and adolescents[J]. Chin J Evid Based Pediatr, 2017, 12(6): 401-409. doi: 10.3969/j.issn.1673-5501.2017.06.001
[13]	健康中国行动推进委员会. 健康中国行动(2019-2030年)[EB/OL]. [2020-09-01]. http://www.gov.cn/xinwen/2019-07/15/content_5409694.htm. Healthy China Action Promotion Committee. Healthy China action (2019-2030)[EB/OL]. [2020-09-01]. http://www.gov.cn/xinwen/2019-07/15/content_5409694.htm.
[14]	HOSMER D W, LEMESHOW S. Confidence interval estimation of interaction[J]. Epidemiology, 1992, 3(5): 452-456. doi: 10.1097/00001648-199209000-00012
[15]	林蓉, 陈思宇, 刘伟, 等. 广州市城区小学生营养状况分析[J]. 中国学校卫生, 2016, 37(12): 1868-1870. https://www.cnki.com.cn/Article/CJFDTOTAL-XIWS201612036.htm LIN R, CHEN S Y, LIU W. Analysis of nutritional status of pupils in Guangzhou city[J]. Chin J Sch Health, 2016, 37(12): 1868-1870. https://www.cnki.com.cn/Article/CJFDTOTAL-XIWS201612036.htm
[16]	邓煜盛. LncRNA HOTAIR调控通路遗传变异与腹型肥胖和脂肪分布的关联研究[D]. 广州: 广东药科大学, 2018. DENG Y S. Association of genetic variation of LncRNA HOTAIR signaling pathway with abdominal obesity and fat disteibution in children adolescents[D]. Guangzhou: Guangdong Pharmaceutical University, 2018.
[17]	MASUKUME G, O'NEILL S M, BAKER P N, et al. The impact of caesarean section on the risk of childhood overweight and obesity: new evidence from a contemporary cohort study[J]. Sci Rep, 2018, 8(1): 15113. doi: 10.1038/s41598-018-33482-z
[18]	AJSLEV T A, ANDERSEN C S, GAMBORG M, et al. Childhood overweight after establishment of the gut microbiota: the role of delivery mode, pre-pregnancy weight and early administration of antibiotics[J]. Int J Obes(Lond), 2011, 35(4): 522-529. doi: 10.1038/ijo.2011.27
[19]	BIASUCCIA G, RUBINIA M, RIBONI S, et al. Mode of delivery affects the bacterial community in the newborn gut[J]. Early Hum Dev, 2010, 86(6): S13-S15. http://europepmc.org/abstract/MED/20133091
[20]	TURNBAUGH P J, LEY R E, MAHOWALD M A, et al. An obesity-associated gut microbiome with increased capacity for energy harvest[J]. Nature, 2006, 444(11): 12-28. http://femsle.oxfordjournals.org/lookup/external-ref?access_num=17183312&link_type=MED&atom=%2Ffemsle%2F342%2F1%2F10.atom
[21]	戎芬. 出生体重与环境因素对儿童青少年超重肥胖影响的队列研究[D]. 上海: 复旦大学, 2012. RONG F. Cohort study on influence of birth weight and enviromental factors on overweight and obesity for children and adolescents[D]. Shanghai: Fudan University, 2012.
[22]	STANSFIELD B K, FAIN M E, BHATIA J, et al. Nonlinear relationship between birth weight and visceral fat in adolescents[J]. J Pediatr, 2016, 174(7): 185-192. http://pubmedcentralcanada.ca/pmcc/articles/PMC5711485/
[23]	GASKINS R, LAGASSE L, LIU J, et al. Small for Gestational age and higher birth weight predict childhood obesity in preterm infants[J]. Am J Perinatol, 2010, 27(9): 721-730. doi: 10.1055/s-0030-1253555
[24]	GRUBE M, BERGMANN S, KEITEL A, et al. Obese parents-obese children? Psychological-psychiatric risk factors of parental behavior and experience for the development of obesity in children aged 0-3: study protocol[J]. BMC Public Health, 2013, 13(1): 1193-1193. doi: 10.1186/1471-2458-13-1193
[25]	VANDER H K, OENEMA A, FERREIRA I, et al. A systematic review of environmental correlates of obesity related dietary behaviors in youth(Review)[J]. Health Educ Res, 2007, 22(2): 203-226. http://www.ncbi.nlm.nih.gov/pubmed/16861362