Correlation analysis of lifestyle, family factors associated and precocious puberty

Objective To explore possible lifestyle and family factors associated with precocious puberty,and to provide scientific basis for precocious puberty prevention and treatment.Methods A case-control study was conducted among 126 children with precocious puberty diagnosed by pediatric endocrinologists in Jinhua and 126 controlled children matched with age,sex,during June 2015 to August 2016.Perinatal characteristics,lifestyle,dietary habits,family environment and genetic factors were assessed through questionnaire.Results Average height,weight,BMI,obesity prevalence in precocious puberty group were higher than those in the control group(P<0.05).Binary Logistic regression analysis showed that no nap time (OR =3.135,P<0.01),large amount of food intake (OR=1.944,P=0.002) was risk factor for precocious puberty;high education of mother (OR=0.576,P=0.004),age of menarche of mother(OR=0.645,P<0.01),father engagement(OR=0.763,P=0.038) were protective factors for precocious puberty.Conclusion Further investigation needs to explore the role of healthy lifestyles and family environment in precocious 1puberty 1prevention.