Influencing factors of urinalysis among 0-6 years old children

Objective To explore the influencing factors of abnormal results in term of urine experimental detection indexes among 0-6 years old children,to provide the basis for prevention and treatment of chronic kidney diseases.Methods Children who provided urine samples were sampled by cluster sampling from 10 childcare facilities in Chenguan district in Lanzhou city in 2014.The association were analyzed among Urinalysis,physical examination and questionnaire survey were conducted,the effects of children' own physics,diet,environmental exposure factors,and disease histories of parents on abnormal situation of urine.Results 1 019 Urine samples were tested,which came from 582 boys(57.11%)and 437 girls(42.89%),the first five abnormal results of urinalysis included positive urine vitamin C 421 cases (41.32%),75 cases (7.36%) of positive urine leucocyte,67 cases (6.58%) of positive urobilinogen,61 cases (5.99%) of,positive urine ketonebod 56 cases (5.50%) of hematuria.The results of multivariable logistic regression analysis indicated that the intake of leaded food resulted in an increased positive rate of hematuria (OR=5.04,95%CI=1.26-20.25),the positive rate of urine leucocyte of boys is lower than that of girls(OR =0.10,CI=0.05-0.22);positive rate of urine vitamin C was lower in <1 years old group than that in 4-6 years old group (OR=0.16,95%CI=0.06-0.42),positive rate of urine vitamin C was lower in 2-3years old group than that in 4-6 years old group(OR=0.70,95%CI=0.54-0.91),positive rate of urine vitamin C of children whose parents were with some kidney disease was higher than children whose parents were without any kidney disease(OR=2.50,95%CI=1.58-3.97),positive rate of urine ketone body was higher in boys than that in girls (OR=2.72,95%CI=1.40-5.29),the higher positive rate of urine ketone body is associated with the higher BMI (OR =1.09,95%CI=1.01-1.17).No influential factors were found for the positive rate of urobilinogen.Conclusion The physical condition,diet and family history of kidney disease of children will lead to the abnormal urine.Children should try to avoid leaded food intake,susceptibility of urinary system of girls should be paid more attention to,reasonable intake of nutrients and appropriate weight should be advocated,actively screening urine should be conducted among children with family history of kidney disease especially.