Awareness of core tuberculosis knowledge and willingness for preventive intervention against latent tuberculosis infection among secondary school students in Lanzhou
-
摘要:
目的 了解兰州市中学生结核病防治核心知识知晓情况与结核潜伏感染预防性干预意愿，为学校结核病防控工作提供参考依据。 方法 2024年4—6月，通过分层整群抽样方法选取兰州市4个区(县)共8所学校1 127名初、高中学生，采用自拟问卷进行结核病防治核心知识知晓及结核潜伏感染预防性干预意愿问卷调查。采用χ2检验与二元Logistic回归模型进行数据分析。 结果 兰州市中学生结核病防治核心知识总知晓率为74.48%，核心知识全部知晓率为25.91%；“肺结核是慢性传染性疾病”的单条核心知识知晓率最低，为61.84%。94.85%的学生愿意在诊断为结核潜伏感染后接受预防性干预。多因素Logistic回归分析结果显示，父亲文化程度为初中(OR=3.14，95%CI=1.22~8.08)、高中或中专(OR=3.55，95%CI=1.16~10.86)的学生预防性干预意愿较父亲文化程度为小学及以下的学生高，知晓“怀疑肺结核应去定点医疗机构就诊”的学生预防性干预意愿更高(OR=1.96，95%CI=1.01~3.80)(P值均 < 0.05)。 结论 兰州市中学生结核病防治核心知识总知晓率偏低；结核潜伏感染预防性干预接受意愿较高，且和父亲文化程度与结核病核心知识知晓水平相关。 Abstract:Objective To investigate the awareness of core tuberculosis (TB) knowledge and the willingness to TB preventive intervention among secondary school students in Lanzhou City, so as to provide a reference basis for the prevention and control of TB in schools. Methods From April to June 2024, a total of 1 127 secondary school students from 8 schools in 4 districts (counties) of Lanzhou City were recruited by stratified cluster sampling method to conduct a questionnaire survey on the awareness of core TB knowledge and the willingness for preventive intervention against latent tuberculosis infection. Data were analysed using χ2 test and binary Logistic regression model. Results The overall awareness rate of core TB knowledge among secondary school students in Lanzhou City was 74.48%, while only 25.91% demonstrated awareness of all core knowledge items. The lowest awareness was observed for the item "tuberculosis is a chronic infectious disease" (61.84%). About 94.85% of the students reported willingness to receive preventive interventions after a diagnosis of latent tuberculosis infection. Multifactorial Logistic regression analysis showed that students whose father's education was junior high school (OR=3.14, 95%CI=1.22-8.08), senior high school or secondary vocational school (OR=3.55, 95%CI=1.16-10.86) had a higher willingness to receive preventive interventions than those whose father's education was primary school or below (both P < 0.05). In addition, students who recognized "suspected tuberculosis" were also more likely to express willingness to receive preventive interventions (OR=1.96, 95%CI=1.01-3.80, P < 0.05). Conclusions The total awareness rate of core TB knowledge among secondary school students in Lanzhou City is low; willingness to receive preventive interventions for latent tuberculosis infection is high and it is related to father's literacy and core TB knowledge level. -
Key words:
- Tuberculosis /
- Knowledge /
- Infection /
- Regression analysis /
- Students
1) 利益冲突声明 所有作者声明无利益冲突。2) 康丽雯和张岚为共同第一作者。 -
表 1 兰州市不同组别中学生LTBI预防性干预接受意愿比较
Table 1. Comparison of willingness to receive LTBI preventive intervention among different groups of secondary school students in Lanzhou City
组别 人数 愿意接受干预人数 χ2值 P值 学段 初中 565 537(95.04) 0.08 0.77 高中 562 532(94.66) 性别 男 583 545(93.48) 4.66 0.03 女 544 524(96.32) 民族 汉族 1 103 1 045(94.74) 1.33 0.63 少数民族 24 24(100.00) 户籍地 农村 575 544(94.61) 0.14 0.70 城镇 552 525(95.11) 父亲文化程度 小学及以下 56 48(85.71) 12.99 0.01 初中 436 416(95.41) 高中或中专 335 323(96.42) 大学专科 145 138(95.17) 本科及以上 150 139(92.67) 母亲文化程度 小学及以下 97 90(92.78) 215.22 < 0.01 初中 395 374(94.68) 高中或中专 341 327(95.89) 大学专科 161 154(95.65) 本科及以上 129 120(93.02) 体检频率 从不 416 393(94.47) 1.71 0.79 每半年 64 59(92.19) 每年 286 274(95.80) 每2年 187 177(94.65) 更长时间 174 166(95.40) 是否寄宿 是 171 164(95.91) 0.46 0.50 否 956 905(94.67) 区县 城关区 269 253(94.05) 8.21 0.04 西固区 261 254(97.32) 七里河区 289 274(91.64) 榆中县 308 288(93.51) 肺结核是慢性传染性疾病 知晓 697 660(94.69) 0.10 0.75 不知晓 430 409(95.12) 肺结核传播方式 知晓 742 707(95.28) 0.82 0.37 不知晓 385 362(94.03) 出现哪些症状时应怀疑为肺结核 知晓 1 047 993(94.84) 0.00 0.95 不知晓 80 76(95.00) 怀疑肺结核应去定点医疗机构就诊 知晓 859 822(95.69) 5.21 0.02 不知晓 268 247(92.16) 肺结核能否治愈 知晓 852 812(95.31) 1.46 0.23 不知晓 275 257(93.45) 接受过结核病健康教育 是 611 581(95.09) 0.15 0.70 否 516 488(94.57) 注： ()内数字为接受率/%。 
下载: 导出CSV
表 2 兰州市中学生LTBI预防性干预意愿的多因素Logistic回归分析(n=1 127)
Table 2. Multifactorial Logistic regression analysis of willingness to LTBI preventive intervention among secondary school students in Lanzhou City(n=1 127)
变量 β值 标准误 Wald χ2值 OR值(95%CI) P值 父亲文化程度 小学及以下 1.00 初中 1.14 0.48 5.63 3.14(1.22~8.08) 0.02 高中或中专 1.27 0.57 4.94 3.55(1.16~10.86) 0.03 大学专科 0.94 0.69 1.84 2.56(0.66~9.96) 0.18 本科及以上 0.64 0.71 0.81 1.90(0.47~7.65) 0.37 怀疑肺结核应去定点医疗机构就诊 不知晓 1.00 知晓 0.67 0.34 3.95 1.96(1.01~3.80) 0.05
下载: 导出CSV
-
[1] JACOBSON K R. Tuberculosis[J]. Annals Inter Med, 2017, 166(3): ITC17- ITC32. doi: 10.7326/AITC201702070 [2] 马艳, 成诗明. 加速我国结核潜伏感染筛查与预防性治疗的建议[J]. 实用医学杂志, 2023, 39(11): 1335-1340. doi: 10.3969/j.issn.1006-5725.2023.11.003MA Y, CHENG S M. Suggestions for accelerating screening and preventive treatment of latent tuberculosis infection in China[J]. J Pract Med, 2023, 39(11): 1335-1340. (in Chinese) doi: 10.3969/j.issn.1006-5725.2023.11.003 [3] ZENNER D, BEER N, HARRIS R J, et al. Treatment of latent tuberculosis infection: an updated network Meta-analysis[J]. Annals Inter Med, 2017, 167(4): 248-255. doi: 10.7326/M17-0609 [4] 国家疾病预防控制局, 中华人民共和国国家卫生健康委员会, 中华人民共和国国家发展和改革委员会, 等. 关于印发《全国结核病防治规划(2024—2030年)》的通知[EB/OL]. (2024-11-28)[2025-01-07]. https://www.gov.cn/zhengce/zhengceku/202412/content_6991217.htm .[5] 肖筱, 陈静, 饶立歆, 等. 大学生肺结核患者密切接触者结核分枝杆菌潜伏感染检测方法研究[J]. 结核与肺部疾病杂志, 2021, 2(4): 311-316.XIAO X, CHEN J, RAO L X, et al. Study on the detection method of latent infection of mycobacterium tuberculosis in close contacts of university students with tuberculosis patients[J]. J Tuberc Lung Dis, 2021, 2(4): 311-316. (in Chinese) [6] 董龙雨, 王嘉, 倪帅虎, 等. 我国四省大学生结核病防治核心知识、信念和行为现状的调查分析[J]. 中国防痨杂志, 2024, 46(2): 206-212.DONG L Y, WANG J, NI S H, et al. Survey and analysis of the current status of core knowledge, beliefs and behaviours of tuberculosis control among university students in four provinces in China[J]. Chin J Antituberc, 2024, 46(2): 206-212. (in Chinese) [7] 赵雁林, 陈明亭. 中国结核病防治工作技术指南[M]. 北京: 人民卫生出版社, 2021.ZHAO Y L, CHEN M T. Technical guidelines for tuberculosis control in China[M]. Beijing: People's Medical Publishing House, 2021. (in Chinese) [8] 徐彩红, 赵雁林. 中国结核病预防性治疗指南[M]. 北京: 人民卫生出版社, 2023.XU C H, ZHAO Y L. Guidelines for preventive treatment of tuberculosis in China[M]. Beijing: People's Medical Publishing House, 2023. (in Chinese) [9] 倪帅虎, 陈钢, 王嘉, 等. "十三五"期间我国农村居民结核病健康教育状况及结核病防治核心信息影响因素分析[J]. 中国防痨杂志, 2024, 46(12): 1469-1477.NI S H, CHEN G, WANG J, et al. Analysis of factors influencing the status of tuberculosis health education and core information on tuberculosis control among rural residents in China during the 13th Five-Year Plan period[J]. Chin J Antituberc, 2024, 46(12): 1469-1477. (in Chinese) [10] 赵红梅, 尤心怡, 胡文品, 等. 甘肃省居民结核病防治知识知晓情况及其影响因素分析[J]. 中国健康教育, 2023, 39(9): 851-857, 863.ZHAO H M, YOU X Y, HU W P, et al. Analysis of knowledge of tuberculosis prevention and control and its influencing factors in Gansu Province[J]. Chin J Health Educ, 2023, 39(9): 851-857, 863. (in Chinese) [11] 周建, 李进岚, 洪峰, 等. 贵安新区大学城本科生肺结核知识知晓情况及其影响因素分析[J]. 中国健康教育, 2021, 37(5): 459-462.ZHOU J, LI J L, HONG F, et al. Analysis of tuberculosis knowledge and its influencing factors among undergraduates in university towns in Gui'an New District[J]. Chin J Health Educ, 2021, 37(5): 459-462. (in Chinese) [12] 杨蕊, 苏智阳, 刘宜平, 等. 2020年云南省结核病防治核心信息知晓情况及影响因素分析[J]. 中国防痨杂志, 2023, 45(11): 1045-1051.YANG R, SU Z Y, LIU Y P, et al. Knowledge of core information on tuberculosis control in Yunnan Province in 2020 and analysis of influencing factors[J]. Chin J Antituberc, 2023, 45(11): 1045-1051. (in Chinese) [13] 宋颂, 刘艳, 王忠东, 等. 青岛市公众结核病防治核心信息知晓率及其影响因素分析[J]. 现代预防医学, 2021, 48(23): 4386-4391.SONG S, LIU Y, WANG Z D, et al. Analysis of public awareness of core information on tuberculosis control and its influencing factors in Qingdao[J]. Mod Prev Med, 2021, 48(23): 4386-4391. (in Chinese) [14] 中华人民共和国国务院办公厅关于印发"十三五"全国结核病防治规划的通知[EB/OL]. (2017-02-16)[2024-12-24]. https://www.gov.cn/zhengce/content/2017-02/16/content_5168491.htm .[15] 王倪, 张慧, 黄飞, 等. 在中学开展结核菌潜伏感染者预防性治疗的可行性研究[J]. 疾病监测, 2017, 32(1): 43-47.WANG N, ZHANG H, HUANG F, et al. Feasibility study of preventive treatment for patients with latent tuberculosis infection in secondary schools[J]. Dis Surveil, 2017, 32(1): 43-47. (in Chinese) [16] 王展, 李忠奇, 丁晓艳, 等. 江苏省学生结核潜伏感染者预防性治疗意愿现状及其影响因素[J]. 中国热带医学, 2024, 24(3): 244-251.WANG Z, LI Z Q, DING X Y, et al. Preventive treatment intention of students with latent tuberculosis infection in Jiangsu Province and its influencing factors[J]. China Trop Med, 2024, 24(3): 244-251. (in Chinese) [17] LI Y, ZHENG Y H, LU L P, et al. Acceptance of chemo-prophylaxis for latent tuberculosis infection among high school/college student contacts of tuberculosis patients in Shanghai, China[J]. Biomed Environ Sci, 2018, 31(4): 317-321. [18] 玛依沙·达肯, 陈阳贵, 李德洋, 等. 2021—2022年乌鲁木齐市肺结核家庭密切接触者预防性治疗意愿的影响因素分析[J]. 预防医学情报杂志, 2023, 39(8): 918-925.MAYISHA D K, CHEN Y G, LI D Y, et al. Analysis of factors influencing the willingness of close household contacts of tuberculosis to receive preventive treatment in Urumqi City from 2021 to 2022[J]. J Prev Med Inf, 2023, 39(8): 918-925. (in Chinese) [19] 李源, 赵炫, 刘洁, 等. 2016—2020年淄博市学生结核潜伏感染现状及预防性服药情况分析[J]. 现代预防医学, 2022, 49(11): 1987-1991, 1998.LI Y, ZHAO X, LIU J, et al. Analysis of the status of latent tuberculosis infection and prophylactic drug taking among students in Zibo City from 2016 to 2020[J]. Mod Prev Med, 2022, 49(11): 1987-1991, 1998. (in Chinese) [20] SHARMA N, BASU S, KHANNA A, et al. The intention to receive tuberculosis preventive therapy in adult household contacts of pulmonary TB patients in Delhi, India[J]. J Infect Dev Countr, 2022, 16(2): 298-304. http://pubmed.ncbi.nlm.nih.gov/35298425/ -
点击查看大图
表(2)
计量
- 文章访问数: 18
- HTML全文浏览量: 5
- PDF下载量: 2
- 被引次数: 0
