Association between bedroom nocturnal light exposure and objective sleep parameters in college students
-
摘要:
目的 调查大学生卧室夜间光暴露与客观测量的睡眠参数的关联，为促进大学生睡眠健康提供参考。 方法 2019年9—10月，采用方便抽样法在安徽医科大学、安徽中医药大学2所高校招募365名健康的大学生，建立大学生队列。使用便携式照度计(TES-1339R；Taishi Corp，台湾，中国)连续2 d在个体水平上测量卧室夜间光暴露，通过腕戴式加速计(ActiGraph GT3X-BT, Pensacola, FL)连续7 d客观评估大学生睡眠参数。使用多元线性回归模型检验卧室夜间光暴露与大学生睡眠参数的关联。 结果 相较于夜间平均光照强度较低(< 3 lx)组，夜间平均光照强度较高(≥3 lx)组大学生睡眠效率更低[(93.5±2.7)%, (92.2±2.9)%，t=3.93]、入睡后觉醒时间更长[(24.7±10.3)(29.2±11.2)min，t=-3.66]、运动指数更高(11.0±3.6, 12.2±3.8，t=-2.80)、睡眠碎片化指数更高(20.5±6.5, 23.0±7.0，t=-3.24)(P值均 < 0.01)。多元线性回归模型结果显示，在调整协变量后，相较于夜间平均光照强度较低组，夜间平均光照强度较高组的睡眠效率降低(β=-1.15，95%CI=-1.78~-0.52)，入睡后觉醒时长、运动指数、睡眠碎片化指数均增加[β值(95%CI)分别为3.94(1.55~6.33)，1.05(0.20~1.89)，2.35(0.81~3.88)](P值均 < 0.05)。 结论 夜间光暴露影响大学生睡眠，卧室光照管理有助于提升青少年睡眠质量。 Abstract:Objective To investigate the cross-sectional association between bedroom nocturnal light exposure and objectively measured sleep parameters in college students, so as to provide evidence for promoting sleep health. Methods From September to October 2019, a convenience sampling method was used to recruit 365 healthy college students from two universities in Hefei, establishing a cohort. Bedroom nocturnal light exposure was measured at the individual level for two consecutive days using a portable illuminometer (TES-1339R; Taishi Corp, Taiwan, China). Sleep parameters were objectively measured over seven consecutive days using wrist-worn accelerometers (ActiGraph GT3X-BT, Pensacola, FL). Multiple linear regression models were employed to examine the association between nocturnal light exposure and sleep parameters. Results Compared to the low nocturnal light exposure (< 3 lx) group, the high-exposure (≥3 lx) group exhibited significantly lower sleep efficiency[(93.5±2.7)%, (92.2±2.9)%, t=3.93], longer wake after sleep onset (WASO)[(24.7±90.3)(29.2±11.2)min, t=-3.66], higher movement index(11.0±3.6, 12.2±3.8, t=-2.80), and higher sleep fragmentation index(20.5±6.5, 23.0±7.0, t=-3.24) (all P < 0.01). After adjusting for covariates, multiple linear regression showed that, compared to the low nocturnal light exposure group, the high-exposure group had reduced sleep efficiency (β=-1.15, 95%CI=-1.78 to -0.52), increased WASO [β(95%CI)=3.94(1.55-6.33)], higher movement index[β(95%CI)=1.05(0.20-1.89)], and elevated sleep fragmentation index[β(95%CI)=2.35(0.81-3.88)](all P < 0.05). Conclusions Light exposure at night negatively impacts college students' sleep. Optimizing bedroom lighting management may improve sleep quality in adolescents. -
Key words:
- Light /
- Environmental exposure /
- Sleep /
- Mental health /
- Regression anlaysis /
- Students
1) 利益冲突声明 所有作者声明无利益冲突。 -
表 1 不同夜间光暴露强度组大学生体格检查指标和睡眠参数比较(x±s)
Table 1. Comparison of physical examination indicators and sleep parameters among college student groups with different light at night exposure intensities(x±s)
夜间平均光照强度 人数 BMI/(kg·m-2) 体脂百分比/% 睡眠效率/% 总睡眠时长/min 入睡后觉醒/min 运动指数 睡眠碎片化指数 较低 264 21.5±3.0 28.4±7.4 93.5±2.7 379.4±64.1 24.7±10.3 11.0±3.6 20.5±6.5 较高 101 21.7±3.5 27.6±6.4 92.2±2.9 376.0±62.7 29.2±11.2 12.2±3.8 23.0±7.0 t值 0.44 0.92 3.93 0.46 -3.66 -2.80 -3.24 P值 0.66 0.36 < 0.01 0.65 < 0.01 < 0.01 < 0.01 
下载: 导出CSV
表 2 多时段卧室夜间光暴露与大学生睡眠参数的相关性分析(r值，n=365)
Table 2. Correlational analysis of multi-period bedroom light at night with sleep parameters among university students(r, n=365)
变量 PBL-1 h PBL-4 h LANavg PAL-2 h PAL-1 h SE TST WASO MI PBL-4 h 0.99** LANavg 0.84** 0.85** PAL-2 h 0.15** 0.16** 0.48** PAL-1 h 0.15** 0.16** 0.48** 0.99** SE -0.14** -0.12* -0.14** -0.09 -0.09 TST 0.06 0.06 0.07 0.11* 0.10 0.39** WASO 0.16** 0.14** 0.16** 0.11* 0.11* -0.92** -0.18** MI 0.16** 0.15** 0.11* -0.03 -0.02 -0.71** -0.26** 0.70** SFI 0.18** 0.17** 0.14** 0.01 0.01 -0.73** -0.23** 0.70** 0.81** 注： * P < 0.05，** P < 0.01。
下载: 导出CSV
表 3 多时段卧室夜间光暴露与大学生睡眠参数的多元线性回归分析(n=365)
Table 3. Multivariate linear regression analysis of multi-period bedroom light at night with sleep parameters among university students(n=365)
自变量 SE TST WASO MI SFI β值(95%CI) P值 β值(95%CI) P值 β值(95%CI) P值 β值(95%CI) P值 β值(95%CI) P值 PBL-1 h -0.48(-0.76~-0.20) < 0.01 -2.37(-9.02~4.28) 0.48 1.89(0.83~2.95) < 0.01 0.61(0.24~0.98) < 0.01 1.20(0.52~1.88) < 0.01 PBL-4 h -0.37(-0.65~-0.08) 0.01 -2.16(-8.85~4.52) 0.53 1.31(0.23~2.39) 0.02 0.47(0.10~0.85) 0.01 1.06(0.38~1.75) < 0.01 LANavg -0.32(-0.61~-0.03) 0.03 -2.14(-8.89~4.60) 0.53 1.20(0.08~2.31) 0.04 0.43(0.04~0.82) 0.03 0.80(0.11~1.50) 0.02 PAL-2 h -0.06(-0.36~0.23) 0.67 -1.58(-8.42~5.27) 0.65 -0.15(-1.26~0.96) 0.79 -0.10(-0.49~0.29) 0.62 -0.19(-0.90~0.52) 0.60 PAL-1 h -0.02(-0.32~0.28) 0.90 0.22(-6.69~7.11) 0.95 -0.31(-1.43~0.81) 0.59 -0.08(-0.48~0.31) 0.68 -0.12(-0.83~0.60) 0.75
下载: 导出CSV
-
[1] COMAI S, GOBBI G. Melatonin, melatonin receptors and sleep: moving beyond traditional views[J]. J Pineal Res, 2024, 76(7): e13011. doi: 10.1111/jpi.13011 [2] SONG F, LIN J, ZHANG H, et al. Long-term sleep deprivation-induced myocardial remodeling and mitochondrial dysfunction in mice were attenuated by lipoic acid and N-acetylcysteine[J]. Pharmaceuticals, 2023, 16(1): 51. doi: 10.3390/pharmaceutics16010051 [3] GARCIA C M, SCHRIER E F, CAREY C, et al. Sleep quality among homeless-experienced older adults: exploratory results from the HOPE HOME study[J]. J Gen Intern Med, 2024, 39(3): 460-469. doi: 10.1007/s11606-023-08429-4 [4] WANG Y, LI B, ZHANG C, et al. Group-based sleep trajectories in children and adolescents: a systematic review[J]. Sleep Med Rev, 2024, 75: 101916. doi: 10.1016/j.smrv.2024.101916 [5] PERLIS M L, POSNER D, RIEMANN D, et al. Insomnia[J]. Lancet, 2022, 400(10357): 1047-1060. doi: 10.1016/S0140-6736(22)00879-0 [6] YANG Z K. Insomnia spreads among young Chinese[N/OL]. (2019-03-21)[2024-05-30]. https://www.chinadaily.com.cn/global/2019-03-21/content_37450197.htm .[7] KRISTJÁNSSON T Ó, STONE K L, SORENSEN H B D, et al. Mortality risk assessment using deep learning-based frequency analysis of EEG and EOG in sleep[J]. Sleep, 2024, 48(2): zsae219. [8] LIU X. Trajectories of sleep problems and the longitudinal associations with mental health difficulties among Chinese adolescents[J]. Soc Sci Med, 2024, 358: 117203. doi: 10.1016/j.socscimed.2024.117203 [9] JASPAN V N, GREENBERG G S, PARIHAR S, et al. The role of sleep in cardiovascular disease[J]. Curr Atheroscler Rep, 2024, 26(7): 249-262. doi: 10.1007/s11883-024-01207-5 [10] LANZA G, MOGAVERO M P, SALEMI M, et al. The triad of sleep, immunity, and cancer: a mediating perspective[J]. Cells, 2024, 13(15): 1246. doi: 10.3390/cells13151246 [11] SIEGEL J M. Sleep function: an evolutionary perspective[J]. Lancet Neurol, 2022, 21: 937-946. doi: 10.1016/S1474-4422(22)00210-1 [12] JÄGERBRAND A K, SPOELSTRA K. Effects of anthropogenic light on species and ecosystems[J]. Science, 2023, 380(6650): 1125-1130. doi: 10.1126/science.adg3173 [13] XU Y X, ZHANG J H, TAO F B, et al. Association between exposure to light at night (LAN) and sleep problems: a systematic review and Meta-analysis of observational studies[J]. Sci Total Environ, 2023, 857(Pt 1): 159303. [14] SADEH A, SHARKEY K M, CARSKADON M A. Activity-based sleep-wake identification: an empirical test of methodological issues[J]. Sleep, 1994, 17(3): 201-207. doi: 10.1093/sleep/17.3.201 [15] MITSUI K, SAEKI K, TONE N, et al. Short-wavelength light exposure at night and sleep disturbances accompanied by decreased melatonin secretion in real-life settings: a cross-sectional study of the HEIJO-KYO cohort[J]. Sleep Med, 2022, 90: 192-198. doi: 10.1016/j.sleep.2022.01.023 [16] ESAKI Y, KITAJIMA T, OBAYASHI K, et al. Light exposure at night and sleep quality in bipolar disorder: the APPLE cohort study[J]. J Affect Disord, 2019, 257: 314-320. doi: 10.1016/j.jad.2019.07.031 [17] CHO C H, LEE H J, YOON H K, et al. Exposure to dim artificial light at night increases REM sleep and awakenings in humans[J]. Chronobiol Int, 2016, 33(1): 117-123. doi: 10.3109/07420528.2015.1108980 [18] WALKER W N, BUMGARNER J R, BECKER-KRAIL D D, et al. Light at night disrupts biological clocks, calendars, and immune function[J]. Semin Immunopathol, 2022, 44(2): 165-173. doi: 10.1007/s00281-021-00899-0 [19] ETO T, OHASHI M, NAGATA K, et al. Crystalline lens transmittance spectra and pupil sizes as factors affecting light-induced melatonin suppression in children and adults[J]. Ophthalmic Physiol Opt, 2021, 41(4): 900-910. doi: 10.1111/opo.12809 [20] FATEMEH G, SAJJAD M, NILOUFAR R, et al. Effect of melatonin supplementation on sleep quality: a systematic review and Meta-analysis of randomized controlled trials[J]. J Neurol, 2022, 269(1): 205-216. doi: 10.1007/s00415-020-10381-w [21] CYR M, ARTENIE D Z, AL B A, et al. The effect of evening light on circadian-related outcomes: a systematic review[J]. Sleep Med Rev, 2022, 64: 101660. doi: 10.1016/j.smrv.2022.101660 [22] MEKSCHRAT L, STRABER T, GHASSABEI S, et al. Light exposure on alertness after wake-up in healthy men: comparing dim, bright, red, and blue light[J]. Neuropsychobiology, 2024, 83(5/6): 183-192. [23] FIGUEIRO M G, SAHIN L, WOOD B, et al. Light at night and measures of alertness and performance: implications for shift workers[J]. Biol Res Nurs, 2016, 18(1): 90-100. doi: 10.1177/1099800415572873 [24] LUNN R M, BLASK D E, COOGAN A N, et al. Health consequences of electric lighting practices in the modern world: a report on the national toxicology program's workshop on shift work at night, artificial light at night, and circadian disruption[J]. Sci Total Environ, 2017(607/608): 1073-1084. -
点击查看大图
表(3)
计量
- 文章访问数: 22
- HTML全文浏览量: 11
- PDF下载量: 3
- 被引次数: 0
