Elevated blood pressure and its association with dietary patterns among Chinese children and adolescents aged 7-17 years
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摘要:
目的 了解中国儿童青少年血压偏高状况及其与膳食模式之间的关系,为开展儿童青少年高血压的饮食干预提供参考。 方法 数据来源于2019—2021年“中国0~18岁儿童营养与健康系统调查与应用项目”,采用分层整群随机抽样方法,从中国东北、华北、西北、华东、华中、华南和西南七大区域的28个调查点抽取7 933名研究对象。采用多因素Logistic回归模型分析人口学特征及营养状况与儿童青少年血压偏高关联;采用探索性因子分析提取调查对象膳食模式,将膳食模式按照因子得分依从性由高到低进行三分位分组(T3、T2、T1),并用多因素Logistic回归模型分析血压偏高与膳食模式的相关性。 结果 中国7~17岁儿童青少年血压偏高检出率为15.4%,不同营养状况(以消瘦为参照,正常:OR=1.57,超重:OR=2.61,肥胖:OR=3.85)、城乡(以农村为参照,城市:OR=0.86)和父亲学历(以初中及以下为参照,本科及以上:OR=0.68)的儿童青少年血压偏高检出率差异均有统计学意义(P值均 < 0.05)。4种膳食模式(主食、动物性食物、零食、蔬菜水果)T3组儿童青少年血压偏高检出率分别为15.7%,14.6%,16.8%,15.8%。多因素Logistic回归分析结果显示,调整城乡、父亲文化程度和营养状况后,零食膳食模式(主要包括糖果类、含糖饮料和膨化食品)T2(OR=1.21)、T3(OR=1.19)组与儿童青少年血压呈正向关联(P值均 < 0.05)。 结论 零食膳食模式是儿童青少年血压偏高的相关因素,控制儿童青少年不健康零食的摄入有助于促进血压健康。 Abstract:Objective To understand the prevalence of elevated blood pressure and its association with dietary patterns in children and adolescents in China, providing evidence for developing dietary intervention of hypertension in children and adolescents. Methods Data were derived from the China Children's Nutrition and Health System Survey and Application Project(2019-2021). A stratified cluster random sampling method was used to include 7 933 participants from 28 survey sites in seven major regions of Northeast, North, Northwest, East, Central, South and Southwest China. Multivariate Logistic regression models were used to analyze associations between demographic characteristics, nutritional status and elevated blood pressure. Exploratory factor analysis identified dietary patterns, which were divided into three quartile groups (T3, T2, T1) based on factor scores (compliance for dietary pattern) from high to low, and multivariate Logistic regression model assessed the correlation between elevated blood pressure and dietary patterns. Results The prevalence of elevated blood pressure was 15.4% among Chinese children aged 7-17 years. Significant differences were observed across nutritional status (reference: underweight; normal weight: OR=1.57; overweight: OR=2.61; obesity: OR=3.85), urban/rural residence (reference: rural; urban: OR=0.86), and paternal education (reference: junior high school and below; bachelor degree or above: OR=0.68) (P < 0.05). The detection rates of high blood pressure in T3 group children and adolescents with four dietary patterns (staple food, animal based food, snacks, vegetables and fruits) were 15.7%, 14.6%, 16.8%, and 15.8%, respectively. After adjusting for residence, paternal education, and nutritional status, the "snack dietary pattern" (mainly candy, sugar-sweetened beverages, and processed snacks) showed positive associations with elevated blood pressure in T2 (OR=1.21) and T3 (OR=1.19) tertiles (P < 0.05). Conclusions The snack dietary pattern is a related factor for elevated blood pressure in children and adolescents. Restricting unhealthy snack intake may promote cardiovascular health. -
Key words:
- Child /
- Adolescent /
- Hypertension /
- Diet /
- Regression analysis
1) 利益冲突声明 所有作者声明无利益冲突。 -
表 1 不同组别7~17岁儿童青少年血压偏高检出率及Logistic逐步回归分析
Table 1. Logistic stepwise regression analysis on the prevalence of elevated blood pressure in children and adolescents aged 7-17 years with different groups
组别 选项 人数 检出人数 检出率/% OR值(95%CI) 性别 男 3 961 603 15.2 1.00 女 3 972 616 15.5 0.91(0.81~1.04) 年龄/岁 7~12 4 310 661 15.3 1.00 13~17 3 623 558 15.4 0.93(0.82~1.06) 城乡 农村 3 952 669 16.9 1.00 城市 3 981 550 13.8 0.86(0.76~0.98)* 营养状况 消瘦 481 43 8.9 1.00 正常 5 322 683 12.8 1.57(1.28~1.93)** 超重 1 144 222 19.4 2.61(2.21~3.08)** 肥胖 986 271 27.5 3.85(2.73~5.43)** 睡眠时间 满足 3 536 526 14.9 1.00 不满足 4 397 693 15.8 1.08(0.95~1.23) 每日身体活动时间/min ≥60 731 100 13.7 1.00 <60 7 202 1 119 15.5 0.83(0.67~1.04) 父亲学历 初中及以下 4 147 687 16.6 1.00 高中/大专 2 471 356 14.4 0.90(0.72~1.13) 本科及以上 1 315 176 13.4 0.68(0.53~0.86)** 母亲学历 初中及以下 4 199 656 15.6 1.00 高中/大专 2 492 387 15.5 0.87(0.73~1.03) 本科及以上 1 242 176 14.2 0.87(0.68~1.11) 家庭年总收入/万元 <10 5 478 862 15.7 1.00 ≥10 2 455 357 14.5 1.05(0.92~1.21) 注:* P<0.05,** P<0.01。 表 2 儿童青少年4种膳食模式与食物组因子载荷
Table 2. Four dietary patterns and food group factor loadings among children and adolescents
食物组 主食 动物性食物 零食 蔬菜水果 谷类 0.66 0.16 -0.07 0.14 薯类 0.79 -0.03 0.07 0.12 豆类 0.70 0.07 0.11 0.21 蔬菜类 0.16 0.13 -0.06 0.75 菌藻类 0.16 0.09 0.35 0.42 水果类 0.14 0.03 0.12 0.80 乳类 0.06 0.37 0.20 0.34 畜肉 0.11 0.73 0.19 0.16 禽肉 0.11 0.76 0.01 -0.04 蛋类 0.00 0.36 0.26 0.16 动物血及肝脏 0.00 0.11 0.20 0.02 水产品 0.03 0.80 0.09 0.10 坚果类 0.04 0.06 0.72 0.17 烘烤食品 0.47 0.13 0.34 0.07 膨化食品 0.53 0.02 0.46 -0.16 糖果类 0.01 0.07 0.71 0.13 含糖饮料 0.15 0.15 0.61 -0.07 特征根 3.82 1.67 1.44 1.20 方差贡献率/% 22.44 9.80 8.50 7.06 累计方差贡献率/% 22.44 32.24 40.74 47.80 表 3 儿童青少年不同膳食模式与血压偏高关联性分析[OR值(95%CI),n=7 933]
Table 3. Association analysis of elevated blood pressure and different dietary patterns among children and adolescents [OR(95%CI), n=7 933]
膳食模式 组别 模型1 模型2 模型3 主食 T1 1.00 1.00 1.00 T2 1.02(0.88~1.19) 1.00(0.86~1.16) 0.99(0.85~1.16) T3 0.98(0.84~1.14) 0.95(0.82~1.11) 0.94(0.81~1.09) 动物性食物 T1 1.00 1.00 1.00 T2 1.03(0.89~1.20) 0.99(0.86~1.15) 1.02(0.88~1.19) T3 1.12(0.96~1.29) 1.02(0.87~1.19) 1.04(0.89~1.22) 零食 T1 1.00 1.00 1.00 T2 1.19(1.03~1.39)* 1.23(1.05~1.42)** 1.21(1.04~1.41)** T3 1.17(1.01~1.36)* 1.21(1.04~1.41)* 1.19(1.03~1.39)* 蔬菜水果 T1 1.00 1.00 1.00 T2 0.94(0.81~1.10) 0.96(0.83~1.12) 0.97(0.83~1.13) T3 0.92(0.79~1.07) 0.94(0.81~1.10) 0.98(0.84~1.15) 注:* P<0.05,** P<0.01;因变量血压偏高以否为参照。 -
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