山西省2014—2023年流行性腮腺炎流行病学特征分析

杨蓓; 霍俊锋; 杨倩; 王晓芳; 陈霄

doi:10.16835/j.cnki.1000-9817.2025160

山西省2014—2023年流行性腮腺炎流行病学特征分析

doi: 10.16835/j.cnki.1000-9817.2025160

杨蓓¹,
霍俊锋^1, ,,
杨倩²,
王晓芳³,
陈霄³

1.
山西省疾病预防控制中心科教科，太原 030032
2.
山西省疾病预防控制中心信息科
3.
山西省疾病预防控制中心免疫科

基金项目:

山西省卫生健康委课题项目 201601098

详细信息

作者简介:
杨蓓(1991-)，女，山西临汾人，硕士，主管医师，主要研究方向为现场流行病学培训项目、传染病监测预警

通讯作者:
霍俊锋，E-mail：huojf1976@126.com

利益冲突声明 所有作者声明无利益冲突。
中图分类号: R179 R181.3⁺² R152.1
计量
- 文章访问数: 8
- HTML全文浏览量: 3
- PDF下载量: 3
- 被引次数: 0
出版历程
- 收稿日期: 2024-12-30
- 修回日期: 2025-03-20
- 网络出版日期: 2025-06-07
- 刊出日期: 2025-05-25

Epidemiological characteristics of mumps in Shanxi Province from 2014 to 2023

1.
Science and Education Section, Shanxi Provincial Center for Disease Control and Prevention, Taiyuan (030032), Shanxi Province, China

摘要

摘要: 目的分析2014—2023年山西省流行性腮腺炎(流腮)分布特征，为制定更具针对性的防控策略提供科学依据。方法通过中国疾病预防控制信息系统收集山西省流腮发病数据，对2014—2023年流腮报告发病率进行描述流行病学和年龄-时期-队列模型(APC)分析。结果 2014—2023年山西省共报告流腮44 360例，年均报告发病率为11.78/10万；2017—2019年高发，发病率分别为21.00/10万、16.76/10万、19.51/10万。男性发病率(13.50/10万)高于女性(9.98/10万)；5~9岁是流腮的高发年龄段，占总病例数的47.29%；2017与2019年5~15岁人群发病率高，分别为155.08/10万、131.78/10万。0~20岁高发人群的报告发病率APC模型年龄效应、时期效应、出生队列效应均有统计学意义(P值均 < 0.05)，年龄相对危险度(RR值)由0岁组的1.75降至20岁组的0.33，出生队列RR值由1994年的2.58下降至2023年的0.26，0~20岁人群发病风险随时间的推移呈先升高再下降的趋势，其中2017年最高(RR=1.23)、2023年最低(RR=0.29)。结论山西省流腮发病存在周期性流行风险，中小学生是流腮防控的重点人群。应做好学校卫生管理工作，加强重点地区流腮监测和适龄儿童2剂次含腮腺炎成分疫苗常规接种。
- 流行性腮腺炎 /
- 流行病学研究 /
- 发病率 /
- 模型 /
- 统计学
Abstract: Objective To analyze the epidemiological characteristics of mumps in Shanxi Province from 2014 to 2023, so as to provide scientific evidence for targeted prevention strategies. Methods Mumps case data in Shanxi Province were obtained from the China Information System for Disease Prevention and Control. Descriptive epidemiological analysis and age-period-cohort (APC) analysis were carried out on the reported incidence of mumps from 2014 to 2023. Results A total of 44 360 mumps cases were reported in Shanxi Province from 2014 to 2023, with an average annual incidence rate of 11.78/100 000. The incidence rates were high during 2017-2019, which were 21.00/100 000, 16.76/100 000, and 19.51/100 000, respectively. Males had a higher incidence rate (13.50/100 000) than females (9.98/100 000). Children aged 5-9 years were the most affected group, accounting for 47.29% of total cases. In 2017 and 2019, incidence rates among the 5-15-year-old group were particularly high, reaching 155.08/100 000 and 131.78/100 000, respectively. The APC model age effect, period effect and cohort effect of the reported incidence rate in the high-incidence population aged 0-20 years all had statistical significance (P < 0.05). The age-relative risk (RR) decreased from 1.75 in the 0-year-old group to 0.33 in the 20-year-old group, and the birth cohort-RR decreased from 2.58 in 1994 to 0.26 in 2023. The morbidity risk of the population aged 0-20 years showed a trend of first increasing and then decreasing over time, among which it was the highest in 2017 (RR=1.23) and the lowest in 2023 (RR=0.29). Conclusions Shanxi exhibits cyclical mumps epidemics, with school-aged children as the high-risk population. School health management work should be carried out, and the surveillance of mumps in high-risk areas and the routine vaccination of two doses of mumps-containing vaccines for eligible children should be strengthened.
- Mumps /
- Epidemiologic studies /
- Incidence /
- Models /
- Statistical
注释:

1) 利益冲突声明 所有作者声明无利益冲突。

HTML全文

图 1 山西省2014—2023年流腮报告发病率APC模型

注：虚线为95%CI。

Figure 1. APC model of reported incidence rates of mumps in Shanxi Province from 2014 to 2023

下载: 全尺寸图片幻灯片

图 2 山西省流腮高发地区2014—2023年报告发病率APC模型

注：虚线为95%CI。

Figure 2. APC model of reported incidence rates of mumps in high incidence areas of Shanxi Province from 2014 to 2023

下载: 全尺寸图片幻灯片

参考文献(25)

[1]	黄昌, 唐金芳, 梁灵芝, 等. 2017—2022年南宁市流行性腮腺炎流行特征变化分析[J]. 中国疫苗和免疫, 2023, 29(3): 315-319. HUANG C, TANG J F, LIANG L Z, et al. Epidemiological changes of mumps in Nanning City, 2017-2022[J]. Chin J Vaccin Immun, 2023, 29(3): 315-319. (in Chinese)
[2]	刘丽莎, 张宁, 李轩, 等. 2010—2021年安徽省流行性腮腺炎的时空流行特征[J]. 中华疾病控制杂志, 2024, 28(2): 146-151. LIU L S, ZHANG N, LI X, et al. Spatiotemporal and epidemiological characteristics of mumps in Anhui Province, 2010-2021[J]. Chin J Dis Control Prev, 2024, 28(2): 146-151. (in Chinese)
[3]	王玲玲, 王旭雯. 无锡市含腮腺炎成分疫苗纳入国家扩大免疫规划对流行性腮腺炎发病影响[J]. 现代预防医学, 2022, 49(6): 1128-1132. WANG L L, WANG X W. Impact of inclusion of mumps-containing vaccine into expanded national immunization program on mumps incidence in Wuxi[J]. Mod Prev Med, 2022, 49(6): 1128-1132. (in Chinese)
[4]	中华人民共和国国家卫生健康委, 中华人民共和国财政部, 中华人民共和国工业和信息化部, 等. 关于国家免疫规划脊髓灰质炎疫苗和含麻疹成分疫苗免疫程序调整相关工作的通知[J]. 中华人民共和国国家卫生健康委员会公报, 2019(12): 25-26. National Health Commission of the PRC, Ministry of Finance fo the PRC, Ministry of Industry and Information Technology of the PRC, et al. Notice on adjusting the immunization schedules for poliomyelitis vaccines and measles-containing vaccines in the national immunization program[J]. Gaz Natl Health Comm PRC, 2019(12): 25-26. (in Chinese)
[5]	李平, 王富珍, 杨宏, 等. 中国2004—2021年流行性腮腺炎流行病学特征和时空聚集性[J]. 中国疫苗和免疫, 2023, 29(1): 19-24. LI P, WANG F Z, YANG H, et al. Epidemiological characteristics and spatiotemporal aggregation of mumps in China from 2004 to 2021[J]. Chin J Vaccin Immun, 2023, 29(1): 19-24. (in Chinese)
[6]	汤家炜, 汤其宁, 朱时雨, 等. 2015—2019年中国法定传染病发病趋势分析[J]. 医学动物防制, 2024, 40(1): 4-7. TANG J W, TANG Q N, ZHU S Y, et al. Analysis of the incidence trend of notifiable infectious diseases in China from 2015 to 2019[J]. J Med Pest Control, 2024, 40(1): 4-7. (in Chinese)
[7]	中华人民共和国卫生部. 流行性腮腺炎诊断标准: WS 270—2007[S]. 北京: 人民卫生出版社, 2008. Ministry of Health of the PRC. Diagnostic criteria for mumps: WS 270-2007[S]. Beijing: People's Medical Publishing House, 2008. (in Chinese)
[8]	巢婷婷, 栾琳, 张钧, 等. 2017—2021年苏州市流行性腮腺炎流行病学分析[J]. 中国校医, 2022, 36(12): 893-896. CHAO T T, LUAN L, ZHANG J, et al. Epidemiological analysis of mumps in Suzhou from 2017 to 2021[J]. Chin J School Doctor, 2022, 36(12): 893-896. (in Chinese)
[9]	XU D, HU J, WANG S, et al. Trends in the prevalence of hypertensive heart disease in China from 1990 to 2019: a joinpoint and age-period-cohort analysis[J]. Front Public Health, 2022, 10: 833345. doi: 10.3389/fpubh.2022.833345
[10]	GAO D, ZOU Z, ZHANG W, et al. Age-period-cohort analysis of HIV mortality in China: data from the global burden of disease study 2016[J]. Sci Rep, 2020, 10(1): 7065. doi: 10.1038/s41598-020-63141-1
[11]	LIU X, YU C, BI Y, et al. Trends and age-period-cohort effect on incidence and mortality of prostate cancer from 1990 to 2017 in China[J]. Public Health, 2019, 172: 70-80. doi: 10.1016/j.puhe.2019.04.016
[12]	WANG L, YU C, LIU Y, et al. Lung cancer mortality trends in China from 1988 to 2013: new challenges and opportunities for the government[J]. Int J Environ Res Public Health, 2016, 13(11): 1660-4601.
[13]	LIU X, JIANG J, YU C, et al. Secular trends in incidence and mortality of bladder cancer in China, 1990-2017: a jointpoint and age-period-cohort analysis[J]. Cancer Epidemiol, 2019, 61: 95-103. doi: 10.1016/j.canep.2019.05.011
[14]	OKUI T. Age-period-cohort analysis of cardiovascular disease mortality in Japan, 1995-2018[J]. J Prev Med Public Health, 2020, 53(3): 198-204. doi: 10.3961/jpmph.20.037
[15]	姜春晓, 尤恩情, 刘振武, 等. 2011—2016年合肥市流行性腮腺炎流行病学特征[J]. 中华疾病控制杂志, 2019, 23(8): 1013-1016. JIANG C X, YOU E Q, LIU Z W, et al. Epidemiological characteristics of mumps in Hefei City from 2011 to 2016[J]. Chin J Dis Control Prev, 2019, 23(8): 1013-1016. (in Chinese)
[16]	胡傲容, 肖静, 刘国政, 等. 流行性腮腺炎应急接种后免疫效果及影响因素[J]. 公共卫生与预防医学, 2019, 30(1): 60-62. HU A R, XIAO J, LIU G Z, et al. Analysis of immune effect and influencing factors after emergency inoculation against mumps[J]. J Public Health Prev Med, 2019, 30(1): 60-62. (in Chinese)
[17]	胡伟军, 刘晓宇, 王新华, 等. 用病例对照研究评价流行性腮腺炎疫苗保护效力及疾病暴发原因探析[J]. 实用医学杂志, 2018, 34(22): 3801-3804. HU W J, LIU X Y, WANG X H, et al. Evaluation of the protective efficacy of mumps vaccine using a case-control study and analysis of the causes of disease outbreaks[J]. J Pract Med, 2018, 34(22): 3801-3804. (in Chinese)
[18]	王媛, 朱贞, 邓丽丽, 等. 2018—2019年中国流行性腮腺炎流行特征和病毒基因特征分析[J]. 病毒学报, 2021, 37(2): 356-362. WANG Y, ZHU Z, DENG L L, et al. Analysis of the epidemiology and viral genetic characteristics of mumps in China during 2018-2019[J]. Chin J Virol, 2021, 37(2): 356-362. (in Chinese)
[19]	任艳, 张晶晶, 刘永鹏, 等. 2005—2021年山东省流行性腮腺炎发病的流行特征分析[J]. 山东大学学报(医学版), 2023, 61(1): 106-112. REN Y, ZHANG J J, LIU Y P, et al. Epidemiological characteristics of mumps incidence in Shandong Province from 2005 to 2021[J]. J Shandong Univ(Health Sci), 2023, 61(1): 106-112. (in Chinese)
[20]	SUN X, TANG F, HU Y, et al. High risk of mumps infection in children who received one dose of mumps-containing vaccine: waning immunity to mumps in children aged 2-5 years from kindergartens in Jiangsu Province, China[J]. Hum Vaccin Immun, 2020, 16(7): 1738-1742.
[21]	PENG Y, WANG P, KONG D G, et al. Epidemiological characteristics and spatiotemporal analysis of mumps at township level in Wuhan, China, 2005-2019[J]. Epidemiol Infect, 2023, 151: e63.
[22]	LIN S, RUAN S, GENG X, et al. Non-linear relationships and interactions of meteorological factors on mumps in Jinan, China[J]. Int J Biometeorol, 2021, 65(4): 555-563.
[23]	YU G, YANG R, WEI Y, et al. Spatial, temporal, and spatiotemporal analysis of mumps in Guangxi Province, China, 2005-2016[J]. BMC Infect Dis, 2018, 18(1): 360.
[24]	LIN C Y, SU S B, PENG C J, et al. The incidence of mumps in Taiwan and its association with the meteorological parameters: an observational study[J]. Medicine (Baltimore), 2021, 100(37): e27267.
[25]	张鹏, 蔡晶, 黄淑琼, 等. ARIMA模型和季节指数模型在湖北省流行性腮腺炎发病预测中比较[J]. 公共卫生与预防医学, 2020, 31(6): 29-32. ZHANG P, CAI J, HUANG S Q, et al. Comparativestudy of ARIMA model and seasonal index model in the prediction of mumps in Hubei Province[J]. J Public Health Prev Med, 2020, 31(6): 29-32. (in Chinese)