深圳市幼儿园和学校2017—2023年呼吸道合胞病毒聚集性疫情监测结果

王昕; 房师松; 武伟华; 刘慧; 孙颖; 邹旋; 唐秀娟

doi:10.16835/j.cnki.1000-9817.2024330

深圳市幼儿园和学校2017—2023年呼吸道合胞病毒聚集性疫情监测结果

doi: 10.16835/j.cnki.1000-9817.2024330

王昕¹,
房师松¹,
武伟华¹,
刘慧¹,
孙颖¹,
邹旋²,
唐秀娟^3, ,

1.
广东省深圳市疾病预防控制中心病原微生物检验所, 518055
2.
广东省深圳市疾病预防控制中心办公室
3.
广东省深圳市疾病预防控制中心传染病防控科

基金项目:

国家重点研发计划项目 2023YFE0103200

深圳市科技创新委员会项目 KCXFZ20211020172545006

详细信息

作者简介:
王昕(1979-)，男，湖南省人，硕士，主任医师，主要研究方向为呼吸道病毒传染病

通讯作者:
唐秀娟，E-mail：txj43@126.com

利益冲突声明 所有作者声明无利益冲突。
中图分类号: G478 R181.3⁺² R373.1
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- 被引次数: 0
出版历程
- 收稿日期: 2024-06-26
- 修回日期: 2024-07-26
- 网络出版日期: 2025-04-03
- 刊出日期: 2025-03-25

Surveillance results of respiratory syncytial virus outbreaks in kindergarten and school in Shenzhen, 2017-2023

1.
Pathogen Microorganism Testing Institute, Shenzhen Center for Disease Control and Prevention, Shenzhen (518055), Guangdong Province, China

摘要

摘要: 目的分析2017—2023年深圳市幼儿园和学校呼吸道合胞病毒聚集性疫情监测结果及流行特点，为呼吸道合胞病毒防控提供科学参考。方法收集和分析深圳市幼儿园和学校2017—2023年呼吸道合胞病毒聚集性疫情监测的流行病学资料和实验室检测结果。结果 2017—2023年深圳市共确诊31起发生在幼儿园和学校的呼吸道合胞病毒聚集性疫情，2020年疫情数最多为14起，其次是2023年8起；发病总人数为346名，平均罹患率为22.02%。64.52%的呼吸道合胞病毒疫情发生在幼儿园，其余均发生在中小学校。呼吸道合胞病毒疫情报告最多的月份是9月(18起，占58.06%)，其次是3和10月(均为3起，占9.68%)。在31起呼吸道合胞病毒疫情中共采集244份咽拭子样本，经检测呼吸道病毒阳性169份，阳性率为69.26%；其中呼吸道合胞病毒阳性121份，其他呼吸道病毒阳性57份(9份为2种病毒均阳性)。31起呼吸道合胞病毒疫情中，14起由呼吸道合胞病毒单独引起(占45.16%)，17起由呼吸道合胞病毒和其他呼吸道病毒混合感染引起(占54.84%)。结论深圳市幼儿园和学校在2020年以后报告较多的呼吸道合胞病毒聚集性疫情，其中多发生在幼儿园，高发季节是秋季和春季。
- 呼吸道合胞病毒 /
- 疾病暴发流行 /
- 发病率 /
- 人群监测 /
- 儿童，学龄前
Abstract: Objective To analyze respiratory syncytial virus(RSV) outbreaks surveillance results and the epidemiological characteristics in kindergarten and school in Shenzhen during 2017-2023, so as to provide a scientific reference for control and prevention of RSV. Methods Epidemiological data and surveillance results of RSV outbreaks in kindergarten and school from 2017 to 2023 were collected for descriptive analyses. Results A total of 31 RSV outbreaks were identified in kindergarten and school in 2017-2023 in Shenzhen, 346 cases were reported, the average incidence rate was 22.02%. The most annual RSV outbreaks were reported in 2020 with 14 outbreaks, followed by 8 outbreaks in 2023. A total of 64.52% of RSV outbreaks were identified in kindergarten with rest occurring in primary school or middle school. The greatest monthly count of outbreak was 18 (58.06%) in September, followed by 3 outbreaks (9.68%) in March and October. A total of 244 swab samples were collected, 169 samples were positive for respiratory viruses, the positive rate was 69.26%, 121 samples were positive for RSV, from 31 respiratory syncytical virus outbreaks 57 and samples were positive for other respiratory viruses(9 samples were positive for two respiratory viruses). A toral of 14(45.16%) outbreaks are caused by RSV alone, 17 outbreaks (54.84%) were caused by RSV and other respiratory viruses. Conclusions Most RSV outbreaks in kindergarten and school are reported after 2020 in Shenzhen, most RSV outbreaks occur in kindergarten, peak seasons of RSV outbreaks are autumn and spring.
- Respiratory syncytial viruses /
- Disease outbreaks /
- Incidence /
- Population surveillance /
- Child, preschool
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参考文献(16)

[1]	Global Burden of Disease Pediatrics Collaboration, KYU H H, PINHO C, et al. Global and national burden of diseases and injuries among children and adolescents between 1990 and 2013: findings from the global burden of disease 2013 study[J]. JAMA Pediatr, 2016, 170(3): 267-287.
[2]	LI Y, WANG X, BLAU D M, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis[J]. Lancet, 2022, 399(10340): 2047-2064.
[3]	崔爱利, 朱贞, 毛乃颖, 等. 2009—2021年中国九省份发热呼吸道症候群监测病例中常见病毒感染情况分析[J]. 中华预防医学杂志, 2022, 56(7): 912-918. doi: 10.3760/cma.j.cn112150-20220228-00184 CUI A L, ZHU Z, MAO N Y, et al. Analysis of common viral infection in surveillance cases of febrile respiratory syndrome in 9 provinces of China from 2009 to 2021[J]. Chin J Prev Med, 2022, 56(7): 912-918. (in Chinese) doi: 10.3760/cma.j.cn112150-20220228-00184
[4]	杨旭辉, 于新芬, 张晨烨, 等. 杭州市呼吸道合胞病毒引起幼儿园急性呼吸道感染暴发疫情调查[J]. 中国学校卫生, 2022, 43(1): 142-145. YANG X H, YU X F, ZHANG C Y, et al. Investigation on outbreaks of acute respiratory tract infection caused by respiratory syncytial virus in kindergartens in Hangzhou[J]. Chin J Sch Health, 2022, 43(1): 142-145. (in Chinese)
[5]	赵国兵, 易卫兵, 易显明, 等. 一起感染呼吸道合胞病毒发热疫情的调查报告[J]. 中国校医, 2007, 21(1): 82. ZHAO G B, YI W B, YI X M, et al. Investigation on a fever outbreak caused by respiratory syncytial virus[J]. Chin J School Doctor, 2007, 21(1): 82. (in Chinese)
[6]	中华人民共和国国家卫生和计划生育委员会办公厅关于印发全国流感监测方案(2017年版)的通知[EB/OL].(2017-04-01)[2024-07-25].http://www.nhc.gov.cn/jkj/s3577/201704/ed1498d9e64144738cc7f8db61a39506.shtml .
[7]	崔爱利, 夏百成, 朱贞, 等. 2009—2023年中国16个省份急性呼吸道感染病例中人呼吸道合胞病毒的流行特征分析[J]. 中华预防医学杂志, 2024, 58(7): 945-951. CUI A L, XIA B C, ZHU Z, et al. Epidemiological characteristics of human respiratory syncytial virus among acute respiratory infection cases in 16 provinces of China from 2009 to 2023[J]. Chin J Prev Med, 2024, 58(7): 945-951. (in Chinese)
[8]	国家呼吸系统疾病临床医学研究中心, 中华医学会儿科学分会呼吸学组, 中国医师协会呼吸医师分会儿科呼吸工作委员会, 等. 儿童呼吸道合胞病毒感染诊断、治疗和预防专家共识[J]. 中华实用儿科临床杂志, 2020, 35(4): 241-250. China National Clinical Research Center for Respiratory Diseases, Group of Respirology, Chinese Pediatric Society, Chinese Medical Association, Chinese Medical Doctor Association Committee on Respirology Pediatrics, et al. Chinese experts' consensus statement on diagnosis, treatment and prevention of respiratory syncytial virus infection in children[J]. Chin J Appl Clin Pediatr, 2020, 35(4): 241-250. (in Chinese)
[9]	OBANDO-PACHECO P, JUSTICIA-GRANDE A J, RIVERO-CAL LE I, et al. Respiratory syncytial virus seasonality: a global overview[J]. J Infect Dis, 2018, 217(9): 1356-1364.
[10]	GUO L, DENG S, SUM S, et al. Respiratory syncytial virus seasonality, transmission zones, and implications for seasonal prevention strategy in China: a systematic analysis[J]. Lancet Glob Health, 2024, 12(6): e1005-e1016.
[11]	YU J, LIU C, XIAO Y, et al. Respiratory syncytial virus seasonality, Beijing, China, 2007-2015[J]. Emerg Infect Dis, 2019, 25(6): 1127-1135.
[12]	孙颖, 武伟华, 黄亚兰, 等. 2019—2023年深圳市流感样病例人呼吸道合胞病毒的流行特征分析[J]. 中华预防医学杂志, 2024, 58(8): 1117-1123. SUN Y, WU W H, HUANG Y L, et al. Epidemiological characteristics of human respiratory syncytial virus in influenza-like illness in Shenzhen from 2019 to 2023[J]. Chin J Prev Med, 2024, 58(8): 1117-1123. (in Chinese)
[13]	李静静, 黄建英, 刘妙玲, 等. 广州地区2017—2022年儿童呼吸道感染疾病负担及常见病原体流行特征[J]. 中国感染控制杂志, 2023, 22(1): 44-51. LI J J, HUANG J Y, LIU M L, et al. Disease burden and epidemic characteristics of pathogens causing acute respiratory infection in children in Guangzhou City, 2017-2022[J]. Chin J Infect Control, 2023, 22(1): 44-51. (in Chinese)
[14]	谢嘉慧, 邝璐, 钟家禹, 等. 2018年至2021年广州地区儿童急性呼吸道感染病原体的流行特征[J]. 中华传染病杂志, 2023, 41(2): 137-143. XIE J H, KUANG L, ZHONG J Y, et al. Epidemiological features of pathogens of acute respiratory tract infection in children in Guangzhou Area from 2018 to 2021[J]. Chin J Infect Dis, 2023, 41(2): 137-143. (in Chinese)
[15]	曹贝贝, 翟宇, 段素霞, 等. 2019—2023年河北地区儿童呼吸道合胞病毒流行特征分析[J]. 中华微生物学和免疫学杂志, 2024, 44(2): 142-148. CAO B B, ZHAI Y, DUAN S X, et al. Epidemiological characteristics of respiratory syncytial virus in children in Hebei from 2019 to 2023[J]. Chin J Microbiol Immunol, 2024, 44(2): 142-148. (in Chinese)
[16]	黄晓文, 庞珍珍, 周斐斐, 等. 2018—2023年杭州市儿童呼吸道合胞病毒感染流行特征[J]. 中华医院感染学杂志, 2024, 34(6): 907-911. HUANG X W, PANG Z Z, ZHOU F F, et al. Epidemiological characteristics of respiratory syncytial virus infection in children of Hangzhou from 2018 to 2023[J]. Chin J Nosocomiol, 2024, 34(6): 907-911. (in Chinese)