Associations of sleep quality trajectory and social jetlag with comorbid symptoms of anxiety and depression among college students
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摘要:
目的 探讨大学生睡眠质量轨迹和社会时差与焦虑抑郁症状共患的流行现状及关联,为改善大学生焦虑抑郁症状共患提供理论依据。 方法 于2019年4—5月,在安徽省合肥市和江西省上饶市方便选取2所高校的1 135名学生进行问卷调查,每隔1年随访1次,共调查3次,与基线匹配后有效人数为1 034名大学生。采用自评问卷调查大学生社会时差,分别采用匹兹堡睡眠质量量表(PSQI)、广泛性焦虑障碍问卷-7项(GAD-7)、患者健康问卷(PHQ-9)评估大学生的睡眠质量、焦虑症状和抑郁症状,将GAD-7得分≥5分且PHQ-9得分≥5分的大学生界定为焦虑抑郁症状共患。采用潜类别增长模型(LCGM)分析大学生睡眠质量轨迹,采用二元Logistic回归分析睡眠质量轨迹、社会时差与焦虑抑郁症状共患的关联。 结果 大学生焦虑抑郁共患检出率为16.9%,社会时差≥2 h的检出率为13.8%,睡眠质量总体呈现好转趋势,2种轨迹分别为睡眠质量较好(81.6%)和睡眠质量较差(18.4%)。调整协变量后,二元Logistic回归模型结果显示,睡眠质量较差和社会时差≥2 h与焦虑抑郁症状共患呈正相关(OR值分别为5.94,1.84,P值均 < 0.05)。 结论 大学生睡眠质量较差和社会时差≥2 h会增加焦虑抑郁症状共患的风险,早期筛查和干预睡眠质量以及降低社会时差对改善大学生心理健康有重要意义。 Abstract:Objective To describe the prevalence and the association of sleep quality trajectory, social jetlag and comorbid symptoms of anxiety and depression among college students, in order to provide a theoretical basis for improving the comorbid symptoms of anxiety and depression in college students. Methods A questionnaire survey was conducted among 1 135 college students from two universities in Shangrao, Jiangxi Province and Hefei, Anhui Province from April to May 2019, and were followed up once every one year for a total of three times, with a valid sample size of 1 034 individuals after matching with the baseline survey. A self-assessment questionnaire was used to investigate the social jetlag of college students, the Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire 9 (PHQ-9) were used to evaluate anxiety and depression symptoms, respectively, while the Pittsburgh Sleep Quality Index (PSQI) was used to assess sleep quality. College students with GAD-7 score ≥5 and PHQ-9 score ≥5 were defined as having comorbid anxiety and depression symptoms. Latent class growth model (LCGM) was employed to analyze the sleep quality trajectory of college students, and binary Logistic regression was used to analyze the relationship between social jetlag, sleep quality trajectory and comorbid symptoms of anxiety and depression. Results The detection rate of comorbid symptoms of anxiety and depression among college students was 16.9%, and the detection rate of social jetlag ≥2 h was 13.8%. The sleep quality showed an overall improvement trend, and the two trajectories were good sleep quality (81.6%) and poor sleep quality (18.4%). Binary Logistic regression model showed that poor sleep quality and social jetlag ≥2 h were positively correlated with comorbid symptoms of anxiety and depression (OR=5.94, 1.84, P < 0.05). Conclusions Poor sleep quality and social jetlag ≥2 h in college students increase the risk of comorbid symptoms of anxiety and depression. Early screening and intervention of sleep quality and reduction of social jetlag are crucial for enhancing the mental health of college students. -
Key words:
- Sleep /
- Anxiety /
- Depression /
- Comorbidity /
- Mental health /
- Students
1) 利益冲突声明 所有作者声明无利益冲突。 -
表 1 大学生不同睡眠质量轨迹模型参数(n=1 034)
Table 1. Different trajectory model parameters of sleep quality of college students(n=1 034)
类别 占比/% AIC值 BIC值 aBIC值 熵值 PLMRT值 PBLRT值 1 100.0 14 474.35 14 504.00 14 484.94 2 18.4/81.6 14 284.78 14 329.25 14 300.67 0.70 <0.01 <0.01 3 8.8/50.0/41.2 14 228.22 14 287.52 14 249.40 0.69 0.08 <0.01 4 2.5/41.8/49.0/6.7 14 171.52 14 245.64 14 198.00 0.75 0.24 <0.01 表 2 不同组别大学生焦虑抑郁症状共患检出率比较
Table 2. Comparison of the detection rates of comorbid symptoms of anxiety and depression in college students in different variables
组别 选项 人数 检出人数 χ2值 P值 性别 男 397 70(17.6) 0.23 0.63 女 637 105(16.5) 家庭居住地 农村 576 102(17.7) 0.57 0.45 城镇 458 73(15.9) 自评健康状况 好 850 126(14.8) 18.79 <0.01 一般 171 43(25.1) 差 13 6(46.2) 吸烟 否 933 146(15.6) 11.06 <0.01 是 101 29(28.7) 饮酒 否 791 104(13.1) 34.14 <0.01 是 243 71(29.2) 体力活动 低 188 50(26.6) 19.89 <0.01 中 404 48(11.9) 高 442 77(17.4) 社会时差/h <2 891 138(15.5) 9.45 < 0.01 ≥2 143 37(25.9) 睡眠质量轨迹 较好 844 87(10.3) 143.01 <0.01 较差 190 88(46.3) 注: ()内数字为检出率/%。 -
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