儿童睡眠期间卧室夜间光暴露与体质量指数关联的随访研究

李琪; 周艺; 丁文琴; 左敏; 徐玉祥; 陶芳标; 孙莹

doi:10.16835/j.cnki.1000-9817.2024121

儿童睡眠期间卧室夜间光暴露与体质量指数关联的随访研究

doi: 10.16835/j.cnki.1000-9817.2024121

李琪¹,
周艺¹,
丁文琴¹,
左敏¹,
徐玉祥¹,
陶芳标^{1, 2, 3},
孙莹^{1, 2, 3, ,}

1.
安徽医科大学公共卫生学院儿少卫生与妇幼保健学系，合肥 230032
2.
出生人口与健康教育部重点实验室/环境与人口健康安徽省重点实验室
3.
合肥综合性国家科学中心大健康研究院健康大数据与群体医学研究所

基金项目:

国家自然科学基金面上项目 82373591

详细信息

作者简介:
李琪(2000-)，女，安徽淮南人，在读硕士，主要研究方向为儿童青少年卫生

通讯作者:
孙莹，E-mail: yingsun@ahmu.edu.cn

利益冲突声明 所有作者声明无利益冲突。
中图分类号: R179 R723.14 Q428
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- 被引次数: 0
出版历程
- 收稿日期: 2024-02-20
- 修回日期: 2024-03-20
- 网络出版日期: 2024-04-25
- 刊出日期: 2024-04-25

Follow-up study of the association between bedroom light at night exposure and body mass index in children

LI Qi¹,
ZHOU Yi¹,
DING Wenqin¹,
ZUO Min¹,
XU Yuxiang¹,
TAO Fangbiao^{1, 2, 3},
SUN Ying^{1, 2, 3
, ,}

1.
Department of Maternal, Child & Adolescent Health, School of Public Health, Anhui Medical University, Hefei (230032), Anhui Province, China

摘要

摘要: 目的探讨儿童睡眠期间卧室夜间光(LAN)暴露与1年后随访体质量指数(BMI)的关联，为预防儿童肥胖提供新策略。方法于2021年12月—2022年5月采用整群随机抽样方法在安徽省滁州市天长市2所小学648名儿童中开展LAN暴露测量，使用便携式照度计评估儿童睡眠期间卧室LAN暴露，并于2022年5月开展问卷调查和体格检查，采用多元线性回归模型分析睡眠期间不同时段卧室LAN暴露与1年随访(2023年5月)BMI变化量的关联。结果儿童睡眠期间平均LAN暴露为1.11(0.35，3.24)lx，27.5%的儿童睡眠期间LAN≥3 lx，19.0%的儿童睡眠期间LAN≥5 lx。多元线性回归分析结果显示，调整性别、基线年龄、睡眠时长、家庭月收入、母亲学历后，睡后1 h LAN≥3 lx和睡后1 h LAN≥5 lx组儿童1年后随访BMI分别增加0.25和0.34 kg/m²[β值(95%CI)分别为0.25(0.05~0.44)，0.34(0.12~0.55)，P值均 < 0.05]。结论儿童睡眠期间卧室夜间LAN暴露与1年随访BMI变化量存在正关联。降低睡眠期间卧室LAN暴露水平可能是预防儿童肥胖的有效措施之一。
- 睡眠 /
- 光 /
- 环境暴露 /
- 人体质量指数 /
- 回归分析 /
- 儿童
Abstract: Objective To explore the association between bedroom light at night (LAN) exposure and body mass index (BMI) in children at 1-year follow-up, so as to provide new strategies for obesity prevention. Methods From December 2021 to May 2022, cluster random sampling was conducted, involving 648 children from two primary schools in Tianchang, Chuzhou City, Anhui Province, China, to assess bedroom LAN exposure of children during sleep. A questionnaire survey and physical examination were carried out in May 2022. Multivariate linear regression was performed to analyze the correlation between bedroom LAN exposure and BMI variable quantity at 1-year follow-up (May, 2023). Results The median intensity of bedroom LAN exposure during the sleep episode was [1.11(0.35, 3.24)lx] in children. The proportion of the sample exposed to an average light intensity of ≥3 lx was 27.5%, while 19.0% was exposed to a LAN intensity of ≥5 lx during the sleep episode. In the multivariable linear regression, after adjusting for covariates, including sex, baseline age, sleep duration, family monthly income, and maternal education level, exposure to a 1 h-average post-bedtime LAN intensity of ≥3 lx (β=0.25, 95%CI=0.05-0.44) and LAN≥5 lx (β=0.34, 95%CI=0.12-0.55) was associated with a gain of 0.25 and 0.34 kg/m², respectively, in the children's BMI at the 1-year follow-up (P < 0.05). Conclusions A positive correlation was found between bedroom LAN exposure and BMI variable quantity at 1-year follow-up in children. Thus, reduced bedroom LAN exposure might be useful for interventions aimed at obesity prevention.
- Sleep /
- Light /
- Environmental exposure /
- Body mass index /
- Regression analysis /
- Child
注释:

1) 利益冲突声明 所有作者声明无利益冲突。

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表 1 儿童不同睡眠时段卧室LAN暴露组基线及1年随访BMI比较(x±s, kg/m²)

Table 1. Comparison of baseline and 1-year follow-up BMI of bedroom light at night exposure groups of children at different periods of sleep(x±s, kg/m²)

LAN暴露	选项	人数	统计值	基线	随访
平均睡眠期间LAN≥3 lx	否	470		18.26±3.33	19.23±3.61
	是	178		18.05±3.15	19.25±3.49
			t值	0.71	-0.05
			P值	0.48	0.96
平均睡眠期间LAN≥5 lx	否	525		18.16±3.29	19.16±3.56
	是	123		18.39±3.25	19.57±3.61
			t值	-0.72	-1.15
			P值	0.48	0.25
平均睡后1 h LAN≥3 lx	否	417		18.07±3.12	19.00±3.30
	是	231		18.43±3.55	19.66±3.99
			t值	-1.27	-2.13
			P值	0.21	0.03
平均睡后1 h LAN≥5 lx	否	466		18.15±3.21	19.07±3.44
	是	182		18.34±3.47	19.66±3.87
			t值	-0.67	-1.87
			P值	0.51	0.06
平均觉醒前1 h LAN≥3 lx	否	283		18.32±3.44	19.37±3.65
	是	365		18.11±3.16	19.13±3.52
			t值	0.83	0.83
			P值	0.41	0.41
平均觉醒前1 h LAN≥5 lx	否	353		18.19±3.34	19.23±3.59
	是	295		18.21±3.22	19.25±3.57
			t值	-0.05	0.06
			P值	0.96	0.95

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表 2 儿童不同睡眠时段卧室LAN暴露与1年随访BMI变化量关联的多元线性回归分析(n=645)

Table 2. Multiple linear regression model of different sleep period bedroom light at night exposure and 1-year follow-up BMI variable quantity of children(n=645)

LAN暴露	模型一		模型二
LAN暴露	β值(95%CI)	P值	β值(95%CI)	P值
平均睡眠期间LAN≥3 lx	0.17(-0.04~0.38)	0.12	0.17(-0.05~0.38)	0.13
平均睡眠期间LAN≥5 lx	0.15(-0.09~0.39)	0.22	0.15(-0.09~0.39)	0.22
平均睡后1 h LAN≥3 lx	0.25(0.06~0.45)	0.01	0.25(0.05~0.44)	0.02
平均睡后1 h LAN≥5 lx	0.34(0.13~0.55)	< 0.01	0.34(0.12~0.55)	< 0.01
平均觉醒前1 h LAN≥3 lx	-0.08(-0.27~0.11)	0.40	-0.07(-0.26~0.13)	0.50
平均觉醒前1 h LAN≥5 lx	-0.05(-0.24~0.14)	0.59	-0.04(-0.24~0.16)	0.69
注：模型一为未校正模型；模型二调整了性别、基线年龄、睡眠时长、家庭月收入、母亲学历。

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