大学生社会时差和睡眠质量与心血管代谢风险的关联

陈玉明; 陶舒曼; 邹立巍; 杨娅娟; 谢阳; 李婷婷; 张丹; 曲杨; 翟爽; 陶芳标; 伍晓艳

doi:10.16835/j.cnki.1000-9817.2024116

大学生社会时差和睡眠质量与心血管代谢风险的关联

doi: 10.16835/j.cnki.1000-9817.2024116

陈玉明¹,
陶舒曼²,
邹立巍²,
杨娅娟³,
谢阳¹,
李婷婷¹,
张丹¹,
曲杨¹,
翟爽¹,
陶芳标^{1, 2, 4},
伍晓艳^{1, 2, 4, ,}

1.
安徽医科大学公共卫生学院儿少卫生与妇幼保健学系，合肥 230032
2.
出生人口健康教育部重点实验室/环境与人口健康安徽省重点实验室
3.
安徽医科大学护理学院
4.
国家卫生健康委配子及生殖道异常研究重点实验室

基金项目:

国家自然科学基金项目 82373592

国家自然科学基金项目 82173542

详细信息

作者简介:
陈玉明(2000-)，女，安徽六安人，在读硕士，主要研究方向为儿童青少年健康

通讯作者:
伍晓艳，E-mail: xywu@ahum.edu.cn

利益冲突声明 所有作者声明无利益冲突。
中图分类号: G444 R714.252 Q428
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- 被引次数: 0
出版历程
- 收稿日期: 2024-02-08
- 修回日期: 2024-03-07
- 网络出版日期: 2024-04-25
- 刊出日期: 2024-04-25

Association of social jetlag and sleep quality with cardiometabolic risk in college students

1.
Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei (230032), Anhui Province, China

摘要

摘要: 目的探讨大学生社会时差(SJL)和睡眠质量与心血管代谢风险之间的关联，为改善大学生身体健康提供依据。方法于2021年5—6月采用方便抽样和整群抽样方法抽取安徽省合肥市和江西省上饶市2所高校的318名大学生进行问卷调查和体检。使用自评问卷调查大学生工作日和休息日的就寝时间与起床时间，并根据工作日睡眠中点和休息日睡眠中点计算SJL，使用匹兹堡睡眠质量量表评价大学生睡眠质量。根据生化检查、血压和人体形态学测量结果，获得大学生心血管代谢相关指标并计算心血管代谢风险评分。使用Mann-Whitney U和Kuskal-Wallis H秩和检验比较不同人口统计学特征大学生心血管代谢风险评分差异，使用广义线性模型分析SJL和睡眠质量与心血管代谢风险评分的关联。结果大学生的心血管代谢风险评分为-0.59(-1.85，1.11)分。广义线性模型结果显示，SJL>2 h(β=1.03，95%CI=0.04~2.03)和睡眠质量差(β=1.67，95%CI=0.46~2.87)与大学生心血管代谢风险评分均呈正相关(P值均 < 0.05)；调整性别、吸烟、饮酒、睡眠时型和睡眠时长等协变量后，SJL>2 h(β=1.20，95%CI=0.04~2.03)和睡眠质量差(β=1.82，95%CI=0.55~3.08)与大学生心血管代谢风险评分均呈正相关(P值均 < 0.05)。结论大学生较高SJL和睡眠质量差与心血管代谢风险评分存在关联。应采取措施改善大学生的昼夜节律紊乱和睡眠质量，以降低心血管疾病的发生。
- 睡眠 /
- 心血管系统 /
- 代谢 /
- 模型，统计学 /
- 学生
Abstract: Objective To explore the association of social jetlag(SJL) and sleep quality with cardiometabolic risk in college students, so as to provide evidence for improving the physical health of college students. Methods Convenience sampling and cluster sampling method was used to select 318 college students from two universities in Hefei, Anhui Province and Shangrao, Jiangxi Province for questionnaire survey and physical examination from May to June 2021. A self-rated questionnaire was used to investigate the bedtime and wake-up time of college students on weekdays and weekend. SJL was calculated according to the midpoint of sleep on weekdays and weekeng. The Pittsburgh Sleep Quality Index was used to evaluate sleep quality among college students. According to the results of biochemical blood tests, blood pressure and human morphology, the cardiometabolic indexes of college students were determined, and the cardiometabolic risk score was calculated. Mann-Whitney U and Kruskal-Wallis H rank-sum tests were used to compare the differences of cardiometabolic risk scores among college students with different demographic characteristics. Generalized linear models were used to analyze the association between SJL, sleep quality and cardiometabolic risk scores. Results The cardiometabolic risk score for college students was -0.59(-1.85, 1.11). The results of the generalized linear model indicated that both SJL>2 h (β=1.03, 95%CI=0.04-2.03) and poor sleep quality (β=1.67, 95%CI=0.46-2.87) were positively correlated with the cardiometabolic risk score of the college students (P < 0.05). After adjusting for covariates including sex, smoking, alcohol consumption, sleep time type and sleep duration, there were positive correlation between SJL>2 h (β=1.20, 95%CI=0.04-2.03) and poor sleep quality (β=1.82, 95%CI=0.55-3.08) with cardiometabolic risk scores of college students (P < 0.05). Conclusions Higher SJL and poor sleep quality in college students are associated with cardiometabolic risk scores. Measures should be taken to improve circadian rhythm disturbances and sleep quality in college students to reduce the incidence of cardiovascular disease.
- Sleep /
- Cardiovascular system /
- Metabolism /
- Models, statistical /
- Students
注释:

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表 1 不同组别大学生心血管代谢风险评分比较[M(P₂₅，P₇₅)]

Table 1. Comparison of cardiometabolic risk scores of college students in different groups[M(P₂₅, P₇₅)]

组别	选项	人数	心血管代谢风险评分	Z/H值	P值
性别	男	163	-0.63(-1.87，1.20)	-0.29	0.77
	女	155	-0.48(-1.73，1.10)
吸烟	是	40	-0.60(-2.24，0.87)	-0.80	0.43
	否	278	-0.64(-1.84，1.20)
饮酒	是	75	-0.48(-1.85，0.94)	-0.32	0.75
	否	243	-0.64(-1.84，1.20)
健康状况	好	256	-0.68(-1.85，1.01)	2.59	0.27
	一般	58	-0.23(-1.64，1.38)
	差	4	-1.44(-3.36，2.49)
体力活动	高	155	-0.66(-1.92，0.72)	4.46	0.11
	中等	107	-0.84(-1.73，1.42)
	低	56	0.10(-1.56，3.42)
社会时差/h	<1	187	-0.65(-2.00，0.91)	3.55	0.17
	1~2	95	-0.56(-1.60，1.36)
	>2	36	-0.48(-1.59，3.27)

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