抑郁伴自杀意念大学生的心率变异性分析

李梦甜; 司峰; 尹斐; 金茜; 霍淑慧; 曹建琴

doi:10.16835/j.cnki.1000-9817.2023.12.017

抑郁伴自杀意念大学生的心率变异性分析

doi: 10.16835/j.cnki.1000-9817.2023.12.017

李梦甜¹,
司峰²,
尹斐¹,
金茜¹,
霍淑慧¹,
曹建琴^1, ,

1.
哈尔滨医科大学护理学院，黑龙江 150081
2.
中国标准化研究院国家市场监管重点实验室(人因与工效学)

基金项目:

黑龙江省哲学社会科学研究规划项目 21SHC216

黑龙江省哲学社会科学研究规划项目 19EDB091

黑龙江省自然科学基金项目 LH2020H030

大庆市指导性科技科技计划项目 zdy-2023-51

详细信息

作者简介:
李梦甜(1993-)，女，黑龙江大庆人，在读硕士，主管护师，主要研究方向为青少年及成人心理健康

通讯作者:
曹建琴，E-mail：cjq338@163.com

利益冲突声明 所有作者声明无利益冲突。
中图分类号: B844.2 R714.252 G478
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- 被引次数: 0
出版历程
- 收稿日期: 2023-07-31
- 修回日期: 2023-09-30
- 网络出版日期: 2023-12-26
- 刊出日期: 2023-12-25

Analysis of heart rate variability in college students with depression and suicidal ideation

1.
School of Nursing, Harbin Medical University, Harbin (150081), Heilongjiang Province, China

摘要

摘要: 目的比较抑郁伴自杀意念大学生与抑郁不伴自杀意念大学生心率变异性(HRV)指标的差异，为高校大学生自杀筛查与预防工作提供客观生理依据。方法于2023年3—4月通过网络及校园招募的形式招募黑龙江省大庆市3所高校的60名17~25岁在校抑郁大学生为研究对象，根据是否存在自杀意念，分为抑郁伴自杀意念组(30例)与抑郁不伴自杀意念组(30例)。应用自编一般资料调查表、汉密尔顿抑郁量表(HAMD)、贝克自杀意念问卷(SSI)对大学生进行调查，并于2023年5月对两组被试进行5 min静息HRV数据采集，采用t检验或Mann-Whitney U检验进行统计学分析。结果抑郁伴自杀意念组大学生的SSI和HAMD得分[7.00(4.25，16.00)，40.73±12.88]均高于抑郁不伴自杀意念组[4.50(1.75，6.00)，29.17±8.15](Z/t值分别为-6.64，4.16，P值均 < 0.01)。抑郁伴自杀意念组大学生HRV时域指标中的正常心搏R-R间期标准差(SDNN)、正常R-R心搏间期每隔5 min平均值的标准差(SDANN)、正常R-R间期每隔5 min标准差的平均值(SDNN Index)[42.75(35.03, 60.75)ms，32.75(26.65, 46.88)ms，(298.82±61.61)ms]均低于抑郁不伴自杀意念组[50.80(46.15, 59.68)ms，38.80(34.50, 45.80)ms，(329.20±50.80)ms](Z/t值分别为-2.43，-2.20，-2.08，P值均 < 0.05)。抑郁伴自杀意念组大学生频域指标中的极低频功率(VLF)[0.02(0.02, 0.02)Hz]高于抑郁不伴自杀意念组[0.02(0.01, 0.02)Hz](Z=-2.19，P < 0.05)。结论抑郁伴自杀意念大学生的抑郁水平较高、自主神经功能失衡，HRV或可能成为识别自杀意念的客观生理指标。
- 抑郁 /
- 自杀 /
- 心率 /
- 精神卫生 /
- 学生
Abstract: Objective To compare the differences in heart rate variability (HRV) indicators between depressive college students with and without suicidal ideation, so as to provide a reliable objective physiological basis for suicide screening and prevention among college students. Methods From March to April 2023, a total of 60 college students with depression aged 17-25 years old were recruited from three universities in Daqing City, Heilongjiang Province through online and campus recruitment. They were divided into the depression with suicidal ideation group (30 cases) and the depression without suicidal ideation group (30 cases) based on the presence of suicidal ideation. A screening survey was conducted on college students using a self-designed general information questionnaire, Hamilton Depression Scale (HAMD), and Scale for Suicide Ideation (SSI). In May 2023, 5-minute resting HRV data was collected from the two groups of participants, and statistical analysis was conducted using t-tests or Mann-Whitney U tests. Results The SSI and HAMD scores of college students in the depression group with suicidal ideation [7.00(4.25, 16.00), 40.73±12.88] were higher than those in the depression group without suicidal ideation [4.50(1.75, 6.00), 29.17±8.15] (Z/t=-6.64, 4.16, P < 0.01). The standard deviation of the NN (SDNN), standard deviation of the average NN intervals (SDANN) and standard deviation of the NN interval every 5 minutes (SDNN Index) in the HRV time-domain indicators of college students with depression and suicidal ideation [42.75(35.03, 60.75)ms, 32.75(26.65, 46.88)ms, (298.82±61.61)ms] were lower than those in the depression without suicidal ideation group [50.80(46.15, 59.68)ms, 38.80(34.50, 45.80)ms, (329.20±50.80)ms] (Z/t=-2.43, -2.20, -2.08, P < 0.05). The very low frequency (VLF) in frequency domain indicators of college students with depression and suicidal ideation [0.02(0.02, 0.02)Hz] was higher than that in the depression group without suicidal ideation [0.02(0.01, 0.02)Hz] (Z=-2.19, P < 0.05). Conclusions College students with suicidal ideation have higher levels of depression and imbalanced autonomic nervous system function, and HRV may become an objective physiological indicator for identifying suicidal ideation.
- Depression /
- Suicide /
- Heart rate /
- Mental health /
- Students
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表 1 两组大学生HRV时域指标比较[M(P₂₅, P₇₅), ms]

Table 1. Comparison of HRV Time-Domain Indicators among two groups[M(P₂₅, P₇₅), ms]

组别	人数	SDNN	SDANN	pNN50	RMSSD	SDNN Index^*
抑郁伴自杀意念组	30	42.75(35.03, 60.75)	32.75(26.65, 46.88)	1.15(0.20, 4.15)	33.05(24.20，44.55)	298.82±61.61
抑郁不伴自杀意念组	30	50.80(46.15, 59.68)	38.80(34.50, 45.80)	1.80(0.98, 9.60)	35.05(30.28, 46.83)	329.20±50.80
Z/t值		-2.43	-2.20	-1.80	-1.46	-2.08
P值		0.02	0.03	0.07	0.14	0.04
注： *符合正态分布，用(x±s)表示。

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表 2 两组大学生HRV频域分析指标比较[M(P₂₅, P₇₅)]

Table 2. Comparison of HRV Frequency-Domain Indicators among two groups[M(P₂₅, P₇₅)]

组别	人数	LF/HF	VLF/Hz	LF/Hz	HF/Hz^*
抑郁伴自杀意念组	30	1.30(0.88, 1.80)	0.02(0.02, 0.02)	0.85(0.07, 0.09)	0.26±0.06
抑郁不伴自杀意念组	30	1.24(0.70，2.32)	0.02(0.01, 0.02)	0.08(0.07, 0.09)	0.28±0.06
Z/t值		-0.36	-2.19	-0.28	-1.29
P值		0.72	0.03	0.78	0.20
注： *符合正态分布，用(x±s)表示。

下载: 导出CSV

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