青春期肠道菌群特征及性别二态性研究进展

祝启丽; 刘洋

doi:10.16835/j.cnki.1000-9817.2023.11.035

青春期肠道菌群特征及性别二态性研究进展

doi: 10.16835/j.cnki.1000-9817.2023.11.035

祝启丽,
刘洋^,

中国医科大学健康科学研究院，辽宁沈阳 110112

基金项目:

国家自然科学基金资助项目 72004233

详细信息

作者简介:
祝启丽(1998-)，女，四川泸州人，在读硕士，主要研究方向为青少年肥胖与微生物-宿主互作机制

通讯作者:
刘洋，E-mail: yliu0568@cmu.edu.cn

利益冲突声明 所有作者声明无利益冲突。
中图分类号: R179 R574.4
计量
- 文章访问数: 177
- HTML全文浏览量: 113
- PDF下载量: 26
- 被引次数: 0
出版历程
- 收稿日期: 2023-05-26
- 修回日期: 2023-07-18
- 网络出版日期: 2023-11-27
- 刊出日期: 2023-11-25

Recent advances in intestinal flora characteristics and sexual dimorphism during puberty

ZHU Qili,
LIU Yang^,

Health Sciences Institute, China Medical University, Shenyang (110122), Liaoning Province, China

摘要

摘要: 肠道菌群在人类生命的不同阶段会经历一个动态的定殖和发育过程。在青春期时受性激素水平影响，此阶段开始性别特异性肠道菌群的发育。性激素水平与肠道菌群具有潜在联系，表明肠道菌群与性激素之间很可能具有双向交互作用。此外，微生物群在人类健康中的双向作用证据不断出现。文章通过分析肠道菌群性别二态性、青春期肠道菌群特征及其最新研究进展，探索肠道菌群与性早熟、生殖系统疾病之间的密切联系，并进一步阐释考虑性别因素在肠道微生物群与青春期性早熟及生殖系统相关疾病中的影响机制及治疗措施。
- 青春期 /
- 肠道菌群 /
- 性别特性 /
- 青少年
Abstract: Gut flora undergoes a dynamic colonization and development process at different stages of human life. Sex-specific gut flora development begins during puberty, which is influenced by sex hormone levels. The potential relationship between sex hormone levels, which suggests that there may be a two-way interaction between intestinal flora and sex hormones. In addition, evidence is emerging for bidirectional effects of the microbiome in human health. Therefore, the review presents the dimorphism of intestinal flora, the characteristics of intestinal flora during puberty and the latest research progress, explores the close relationship between intestinal flora and precocious puberty and reproductive system diseases, and further explains the influence mechanism and treatment measures of considering gender factors in intestinal microflora, precocious puberty and reproductive system related diseases.
- Puberty /
- Intestinal bacteria /
- Gender identity /
- Adolescent
注释:

1) 利益冲突声明 所有作者声明无利益冲突。

HTML全文

图 1 不同生命周期肠道菌群特征及青春期性别特异性菌群

Figure 1. Characteristics of intestinal flora at different life cycles and sex-specific flora during puberty

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