Effect of Wuqinxi on the psychological state and prefrontal oxygenated hemoglobin of female college students with subliminal depression
-
摘要:
目的 观察动静结合式五禽戏对阈下抑郁(SD)女大学生心理状态及前额叶氧合血红蛋白的影响, 以期为SD大学生干预方案的优化提供证据。 方法 整群随机选择重庆第二师范学院2021-2022学年2个学期大三年级SD女大学生72人, 采用随机数字表法分为对照组、观察1组、观察2组, 对照组进行常规心理干预, 1次/周, 30 min/次; 观察1组在对照组基础上进行五禽戏锻炼, 2次/d, 约30 min; 观察2组在对照组和观察1组基础上进行动静结合式五禽戏锻炼, 即五禽戏动态锻炼配合五禽戏的运动性引导想象训练, 20 min/d; 3组均干预12周。观察干预前后女大学生的中文版汉密尔顿抑郁量表(HAMD-24)、阈下抑郁量表(STDS)、症状自评量表(SCL-90)得分, 采集血清γ-氨基丁酸(GABA)和血浆促肾上腺皮质激素(ACTH), 并通过近红外脑功能成像(fNIRS)检测前额叶氧合血红蛋白(Oxy-Hb)浓度。 结果 干预后, 观察2组HAMD-24、STDS评分(11.33±1.29, 53.08±2.31)均低于对照组和观察1组(18.27±2.02, 73.60±4.05;15.19±1.92, 64.58±2.69), 差异均有统计学意义(F值分别为8.64, 11.85, P值均 < 0.05)。观察2组SCL-90量表中躯体化、人际关系敏感、抑郁、焦虑、敌对、精神病性6个维度得分均低于其余两组, 差异均有统计学意义(F值分别为3.68, 9.83, 10.37, 5.85, 3.05, 7.46, P值均 < 0.05)。观察2组血浆ACTH均低于其余两组, Oxy-Hb峰值浓度均高于其余两组(F值分别为3.27, 6.08, P值均 < 0.05);观察2组血清GABA水平高于对照组(P < 0.05), 但与观察1组差异无统计学意义(P>0.05)。 结论 动静结合式五禽戏训练可以改善阈下抑郁女大学生心理状态, 缓解抑郁症状, 其机制可能与动静结合式五禽戏提高阈下抑郁女大学生前额叶氧合血红蛋白有关联。 Abstract:Objective To observe the effect of dynamic and static combination of Wuqinxi on the psychological state and prefrontal oxygenated hemoglobin of female college students with subliminal depression (SD), so as to provide a high-quality reference for optimizing their interventional measures. Methods A total of 72 female college students with SD in their third year of two semesters in the 2021-2022 academic year of Chongqing Second Normal University were randomly divided into a control group, an observation group 1, and an observation group 2.The control group received routine psychological intervention once a week, 20 minutes/time, while the observation group 1 received Wuqinxi exercise twice a day for about 30 minutes on the basis of the control group.The observation group 2 received a combination of dynamic and static Wuqinxi exercise on the basis of the control group, Wuqinxi dynamic exercise combined with Wuqinxi exercise guided imagination training about 20 minutes/time.All three groups received 12 weeks of intervention.Observe the Chinese version of the Hamilton Depression Scale (HAMD-24), Subthreshold Depression Scale (STDS), and Symptom Checklist-90(SCL-90) before and after intervention, and collect serum γ-aminobutyric acid (GABA) and plasma adrenocor ticotropic hormone (ACTH), and the concentration of oxyhemoglobin (Oxy Hb) in the prefrontal lobe were detected by functional near-infrared spectroscopy (fNIRS). Results The results showed that the HAMD-24 and STDS scores of the two groups (11.33±1.29, 53.08±2.31) were lower than those of the control group and observation group 1(18.27±2.02, 73.60±4.05;15.19±1.92, 64.58±2.69), with statistically significant differences (F=8.64, 11.85, P < 0.05).Observing that the six dimensions of somatization, interpersonal, depression, anxiety, hostility psychoticism in the SCL-90 scale were lower in the two groups than in the other two groups (F=3.68, 9.83, 10.37, 5.85, 3.05, 7.46, P < 0.05).The plasma ACTH levels in the observation group were lower than those in the other two groups, while the peak concentration of Oxy Hb was higher than those in the other two groups (F=3.27, 6.08, P < 0.05).The serum GABA levels were higher than those in the control group, and there was no difference compared to the observation group 1(P>0.05). Conclusion The combination of dynamic and static Wuqinxi training can improve the psychological state of female college students with subthreshold depression, alleviate the depressive symptoms, possibly through increase of prefrontal oxygenated hemoglobin. -
Key words:
- Depression /
- Mental health /
- Hemoglobin A /
- Intervention studies /
- Students /
- Female
1) 利益冲突声明 所有作者声明无利益冲突。 -
表 1 干预前后3组女大学生HAMD-24、STDS评分比较(x±s)
Table 1. Comparison of HAMD-24 and STDS scores among female college students of three groups before and after intervention(x±s)
干预前后 组别 人数 统计值 HAMD-24 STDS 干预前 对照组 24 22.30±3.06 87.18±4.78 观察1组 24 22.73±2.31 85.84±3.05 观察2组 24 23.01±3.80 87.04±3.91 F值 0.55 0.47 P值 0.52 0.58 干预后 对照组 24 18.27±2.02c 73.60±4.05c 观察1组 24 15.19±1.92b 64.58±2.69b 观察2组 24 11.33±1.29bc 53.08±2.31bc F值 8.64 11.85 P值 < 0.01 < 0.01 注: b为与对照组比较,P < 0.05;c为与观察1组比较,P < 0.05。 表 2 干预前后3组女大学生SCL-90量表各维度得分比较(x±s)
Table 2. Comparison of SCL-90 scores in various dimensions among female college students of threes groups before and after intervention(x±s)
干预前后 组别 人数 统计值 躯体化 强迫症状 人际关系敏感 抑郁 焦虑 干预前 对照组 24 1.52±0.24 1.32±0.28 1.60±0.27 1.66±0.23 1.58±0.32 观察1组 24 1.51±0.20 1.33±0.25 1.61±0.27 1.64±0.23 1.56±0.35 观察2组 24 1.51±0.19 1.34±0.21 1.61±0.26 1.66±0.24 1.58±0.36 F值 0.13 0.21 0.46 0.49 0.42 P值 0.88 0.75 0.58 0.55 0.61 干预后 对照组 24 1.51±0.23c 1.31±0.26 1.54±0.24c 1.52±0.22c 1.50±0.25 观察1组 24 1.48±0.22b 1.32±0.25 1.49±0.22b 1.45±0.22b 1.49±0.26 观察2组 24 1.45±0.23bc 1.32±0.23 1.32±0.25bc 1.30±0.19bc 1.42±0.33bc F值 3.68 0.23 9.83 10.37 5.85 P值 0.03 0.72 < 0.01 < 0.01 < 0.01 干预前后 组别 人数 统计值 敌对 恐怖 偏执 精神病性 其他 干预前 对照组 24 1.50±0.36 1.48±0.28 1.50±0.23 1.53±0.24 1.38±0.24 观察1组 24 1.50±0.37 1.48±0.35 1.51±0.24 1.53±0.25 1.39±0.25 观察2组 24 1.51±0.36 1.49±0.31 1.49±0.22 1.54±0.27 1.40±0.26 F值 0.09 0.47 0.19 0.20 0.23 P值 0.93 0.58 0.78 0.76 0.72 干预后 对照组 24 1.37±0.32 1.40±0.25 1.40±0.22 1.46±0.22c 1.34±0.23 观察1组 24 1.38±0.32 1.38±0.26 1.39±0.19 1.40±0.27b 1.33±0.24 观察2组 24 1.34±0.19bc 1.38±0.31 1.38±0.21 1.31±0.21bc 1.32±0.24 F值 3.05 0.45 0.28 7.46 0.25 P值 0.04 0.59 0.69 < 0.01 0.70 注: b为与对照组比较,P < 0.05;c为与观察1组比较,P < 0.05。 表 3 3组女大学生干预前后血清GABA、血浆ACTH以及Oxy-Hb峰值体积浓度比较(x±s)
Table 3. Comparison of peak concentrations of serum GABA, plasma ACTH, and Oxy-Hb among female college students of three groups before and after intervention(x±s)
组别 人数 干预前 干预后 血清GABA
/(μmol·L-1)血浆ACTH
/(pg·mL-1)Oxy-Hb峰值
/[mmol·(L·mm)-1]血清GABA
/(μmol·L-1)血浆ACTH
/(pg·mL-1)Oxy-Hb峰值
/[mmol·(L·mm)-1]对照组 24 4.82±0.71 38.18±4.13 0.30±0.04 4.85±0.72c 38.42±4.18c 0.31±0.03c 观察1组 24 4.90±0.65 39.15±5.09 0.31±0.03 5.27±0.62b 35.81±5.11b 0.33±0.03b 观察2组 24 4.88±0.81 38.42±4.93 0.30±0.02 5.40±0.69b 32.06±4.35bc 0.39±0.04bc F值 0.20 0.54 0.10 5.75 3.27 6.08 P值 0.77 0.53 0.92 < 0.01 0.03 < 0.01 注: b为与对照组比较,P < 0.05;c为与观察1组比较,P < 0.05。 -
[1] 陈艳艳, 周恩媛, 王雨, 等. 大学生阈下抑郁的运动干预及其机制研究进展[J]. 中国医药导报, 2023, 20(14): 52-55, 64. https://www.cnki.com.cn/Article/CJFDTOTAL-YYCY202314044.htmCHEN Y Y, ZHOU E Y, WANG Y, et al. Research progress on exercise intervention and mechanism in college student subthreshold depression[J]. Chin Med Her, 2023, 20(14): 52-55, 64. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-YYCY202314044.htm [2] 宋旭升. 大学生成人依恋、自尊与阈下抑郁的关系研究[D]. 北京: 北京中医药大学, 2019.SONG X S. A study on the relationship between adult attachment, self-esteem, and subliminal depression among college students[D]. Beijing: Beijing University of Chinese Medicine, 2019. (in Chinese) [3] 段海珍, 曹梅娟, 贺鑫. 大学生阈下抑郁的研究进展[J]. 职业与健康, 2023, 39(1): 118-121. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJK202301025.htmDUAN H Z, CAO M J, HE X. Research progress of subthreshold depression in college students[J]. Occup Health, 2023, 39(1): 118-121. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZYJK202301025.htm [4] 程香, 王冬梅, 陈欣, 等. 健身气功·五禽戏改善轻度抑郁大学生前额叶和海马氢质子磁共振波谱[J]. 南方医科大学学报, 2016, 36(11): 1468-1476. https://www.cnki.com.cn/Article/CJFDTOTAL-DYJD201611005.htmCHENG X, WANG D M, CHEN X, et al. Health Qigong Wuqinxi improves hydrogen proton magnetic resonance spectra in prefrontal cortex and hippocampus in college students with mild depression[J]. J South Med Univ, 2016, 36(11): 1468-1476. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-DYJD201611005.htm [5] HADJIBALASSI M, LAMBRINOU E, PAPASTAVROU E, et al. The effect of guided imagery on physiological and psychological outcomes of adult ICU patients: a systematic literature review and methodological implications[J]. Austr Critic Care, 2017, 31(2): 1-14. [6] SAUNDERS J B, COTTLER L B. The development of the diagnostic and statistical manual of mental disorders version V substance use disorders section: establishing the research framework[J]. Curr Opin Psychiatry, 2007, 20(3): 208-212. doi: 10.1097/YCO.0b013e3280fb2720 [7] 中华医学会精神病学分会. 中国精神障碍分类与诊断标准第三版(精神障碍分类)[J]. 中华精神科杂志, 2001, 34(3): 59-63. https://www.cnki.com.cn/Article/CJFDTOTAL-LCJS201306035.htmPsychiatric Branch of the Chinese Medical Association. Chinese classification and diagnostic standards for mental disorders, third edition (classification of mental disorders)[J]. Chin J Psychiatry, 2001, 34(3): 59-63. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-LCJS201306035.htm [8] 章婕, 吴振云, 方格, 等. 流调中心抑郁量表全国城市常模的建立[J]. 中国心理卫生杂志, 2010, 24(2): 139-143. https://www.cnki.com.cn/Article/CJFDTOTAL-ZXWS201002019.htmZHANG J, WU Z Y, FANG G, et al, Development of the Chinese age norms of CESD in urban area[J]. Chin J Ment Health, 2010, 24(2): 139-143. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZXWS201002019.htm [9] 国家体育总局健身气功管理中心. 健身气功: 五禽戏[M]. 北京: 人民体育出版社, 2006: 5.Fitness Qigong Management Center of the General Administration of Sport of China. Fitness Qigong Wuqinxi[M]. Beijing: People's Sports Publishing House, 2006: 5. (in Chinese) [10] 刘天君. 中医气功[M]. 3版. 北京: 中国中医药出版社, 2012.LIU T J. Traditional Chinese medicine Qigong[M]. 3rd ed. Beijing: China Press of Traditional Chinese Medicine, 2012. (in Chinese) [11] 孙晓艳, 李怡雪, 余灿清, 等. 中文版抑郁量表信效度研究的系统综述[J]. 中华流行病学杂志, 2017, 38(1): 110-116.SUN X Y, LI Y X, YU C Q, et al. A systematic review of the reliability and validity of the Chinese Version of the Depression Scale[J]. Chin J Epidemiol, 2017, 38(1): 110-116. (in Chinese) [12] 张金鹏, 有明妍, 张怡淳子, 等. 阈下抑郁辨识工具及判定标准[J]. 世界中医药, 2019, 14(6): 1425-1428. https://www.cnki.com.cn/Article/CJFDTOTAL-SJZA201906018.htmZHANG J P, YOU M Y, ZHANG Y C Z, et al. Identify tools and diagnostic criteria of subthreshold depression[J]. World Chin Med, 2019, 14(6): 1425-1428. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-SJZA201906018.htm [13] 汪向东, 王希林, 马弘. 心理卫生评定量表手册: 增订版[M]. 北京: 中国心理卫生杂志社, 1999: 31-35, 375-378.WANG X D, WANG X L, MA H. Rating scales of mental healthy: re-vised edition[M]. Beijing: Chinese Mental Health Journal, 1999: 31-35, 375-378. (in Chinese) [14] 王心茹, 邱丽华. 青少年抑郁症性别差异的磁共振脑结构成像研究进展[J]. 临床放射学杂志, 2023, 42(10): 1689-1692. https://www.cnki.com.cn/Article/CJFDTOTAL-LCFS202310027.htmWANG X R, QIU L H. Progress in magnetic resonance brain structural imaging of gender differences in adolescent depressio[J]. J Clin Radiol, 2023, 42(10): 1689-1692. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-LCFS202310027.htm [15] ZHANG J, QIN S, ZHOU Y, et al. A randomized controlled trial ofmindfulness-based Tai Chi Chuan for subthreshold depressionadolescents[J]. Neuropsychiatr Dis Treat, 2018, 14: 2313-2321. [16] 沈鹤军, 曹彦俊, 裴悦, 等. 不同中医运动治未病锻炼对大学生睡眠质量、抑郁与焦虑水平的影响[J]. 中国中医药信息杂志, 2018, 25(2): 15-19. https://www.cnki.com.cn/Article/CJFDTOTAL-XXYY201802004.htmSHEN H J, CAO Y J, PEI Y, et al. Effects of different TCM exercises for preventive treatment of diseases on sleep quality, depression and anxiety of college students[J]. Chin J Inform Tradit Chin Med, 2018, 25(2): 15-19. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-XXYY201802004.htm [17] 陈金霞, 李元昊, 吴英清, 等. 太极拳锻炼对女大学生抑郁情绪及血清炎症因子的影响[J]. 中国学校卫生, 2019, 40(7): 1065-1068. doi: 10.16835/j.cnki.1000-9817.2019.07.029CHEN J X, LI Y H, WU Y Q, et al. The effect of Tai Chi exercise on depression and serum inflammatory factors in female college students[J]. Chin J Sch Health, 2019, 40(7): 1065-1068. (in Chinese) doi: 10.16835/j.cnki.1000-9817.2019.07.029 [18] 张婧怡, 李振, 肖涛. 中医养生功法影响大学生焦虑和抑郁症状的Meta分析[J]. 现代预防医学, 2021, 48(23): 4324-4330. https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF202123022.htmZHANG J Y, LI Z, XIAO T. Meta analysis of the influence of traditional Chinese medicine health preservation techniques on anxiety and depression symptoms in college students[J]. Mod Prev Med, 2021, 48(23): 4324-4330. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-XDYF202123022.htm [19] ELANSARI W, STOCK C, PHILLIPS C, et al. Does the association between depressive symptomatology and physical activity depend on body image perception?A survey of students from seven universities in the UK[J]. Int J Environ Res Public Health, 2011, 8(2): 281-299. [20] 焦晓霞, 纪红, 陈静. 传统五禽戏对女大学生体能及心理健康的影响[J]. 中国学校卫生, 2021, 42(9): 1323-1327. doi: 10.16835/j.cnki.1000-9817.2021.09.011JIAO X X, JI H, CHEN J. The impact of traditional Wuqinxi on the physical and mental health of female college students[J]. Chin J Sch Health, 2021, 42(9): 1323-1327. (in Chinese) doi: 10.16835/j.cnki.1000-9817.2021.09.011 [21] 潘国建, 高幕峰, 吴向科. "健身气功·五禽戏"对女大学生部分生理指标的影响研究[J]. 上海师范大学学报(自然科学版), 2016, 45(1): 115-120. https://www.cnki.com.cn/Article/CJFDTOTAL-SHDZ201601018.htmPAN G J, GAO M F, WU X K. Research on the impact of "Fitness Qigong·Five Poultry Play" on some physiological indicators of female college students[J]. J Shanghai Norm Univ (Natur Sci Edit), 2016, 45(1): 115-120. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-SHDZ201601018.htm [22] 李瑞明, 刘小娟, 郭计东. 运动处方五禽戏临床研究进展[J]. 中国中医药现代远程教育, 2023, 21(2): 193-196. https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYY202302069.htmLI R M, LIU X J, GUO J D. Progress in clinical research on exercise prescription Wuqinxi[J]. Chin Med Mod Dist Educ China, 2023, 21(2): 193-196. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZZYY202302069.htm [23] 姜默琳, 卢伟. 针灸通过谷氨酸/γ-氨基丁酸系统治疗抑郁症机制研究进展[J]. 精神医学杂志, 2022, 35(3): 231-235. https://www.cnki.com.cn/Article/CJFDTOTAL-SDJB202203002.htmJIANG M L, LU W. Acupuncture and moxibustion passes glutamic acid/γ-research progress on the mechanism of aminobutyric acid system in treating depression[J]. J Psychiatry, 2022, 35(3): 231-235. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-SDJB202203002.htm [24] 佟琳, 李作孝, 陈秀, 等. 脑卒中后抑郁患者血清促肾上腺皮质激素研究[J]. 临床精神医学杂志, 2007, 17(2): 118-120. https://www.cnki.com.cn/Article/CJFDTOTAL-LCJS200702029.htmTONG L, LI Z X, CHEN X, et al. Study on serum adrenocorticotropic hormone levels in patients with post-stroke depression[J]. J Clin Psychiatry, 2007, 17(2): 118-120. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-LCJS200702029.htm [25] 吕学玉, 杨扬, 林颖娜, 等. 八段锦结合放松功训练对轻中度抑郁症沉思状态的调节[J]. 辽宁中医杂志, 2022, 49(7): 119-123. https://www.cnki.com.cn/Article/CJFDTOTAL-LNZY202207035.htmLYU X Y, YANG Y, LIN Y N, et al. The regulation of meditation state in mild to moderate depression by combining Ba Duan Jin with relaxation skill training[J]. Liaoning J TCM, 2022, 49(7): 119-123. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-LNZY202207035.htm [26] 马江, 张迪, 赵田芋, 等. 运动想象疗法治疗脊髓损伤的机制及应用前景[J]. 中国组织工程研究, 2022, 26(36): 5897-5904. https://www.cnki.com.cn/Article/CJFDTOTAL-XDKF202236025.htmMA J, ZHANG D, ZHAO T Y, et al. The mechanism and application prospects of motor imagery therapy for spinal cord injury[J]. Chin J Tissus Engineer Res, 2022, 26(36): 5897-5904. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-XDKF202236025.htm [27] 张佳乐, 周霞, 刘建宪, 等. 五音具象催眠技术治疗中风后阈下抑郁疗效[J]. 康复学报, 2022, 32(6): 482-488. https://www.cnki.com.cn/Article/CJFDTOTAL-FYXB202206002.htmZHANG J L, ZHOU X, LIU J X, et al. The therapeutic effect of five tone concrete hypnosis technique on post stroke subthreshold depression[J]. Rehabil Med, 2022, 32(6): 482-488. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-FYXB202206002.htm [28] PAPP M, GRUCA P, LASON M, et al. Insufficiency of ventral hippocampus to medial prefrontal cortex transmission explains antidepressant non-response[J]. J Psychopharmacol, 2021, 35(10): 1253-1264. [29] 罗雅丽, 陈劲松, 陈莎莎, 等. 太极式运动想象疗法对脑梗死患者的运动功能以及fNIRS的影响[J]. 中国康复, 2022, 37(5): 267-271. https://www.cnki.com.cn/Article/CJFDTOTAL-ZLKF202205003.htmLUO Y L, CHEN J S, CHEN S S, et al. The effect of Tai Chi style exercise imagination therapy on motor function and fNIRS in patients with cerebral infarction[J]. Chin J Rehabil, 2022, 37(5): 267-271. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZLKF202205003.htm -

计量
- 文章访问数: 323
- HTML全文浏览量: 206
- PDF下载量: 29
- 被引次数: 0