广州市2012—2020年小儿轮状病毒腹泻与气压的关联

李丽娟; 原皓; 何依伶; 郭巧芝; 赵丹洋; 陈琴

doi:10.16835/j.cnki.1000-9817.2023.09.025

广州市2012—2020年小儿轮状病毒腹泻与气压的关联

doi: 10.16835/j.cnki.1000-9817.2023.09.025

1.
广州市妇女儿童医疗中心医院, 广东 510623
2.
中山大学附属第一医院

基金项目:

广东省中医药局中医药科研项目 20222163

广州市卫生健康科技项目 2021A010022

详细信息

作者简介:
李丽娟(1983-), 女, 河北邯郸人, 博士, 副主任医师, 主要研究方向为医院质量管理、疾病管理

通讯作者:
原皓，E-mail：462810085@qq.com

利益冲突声明 所有作者声明无利益冲突。
中图分类号: R511 R181.3 R179
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- 被引次数: 0
出版历程
- 收稿日期: 2023-07-14
- 修回日期: 2023-07-23
- 网络出版日期: 2023-09-28
- 刊出日期: 2023-09-25

The association between rotavirus diarrhea in children and atmospheric pressure in Guangzhou City from 2012 to 2020

1.
Guangzhou Women and Children's Medical Center, Guangzhou (510623), China

摘要

摘要: 目的探究广州市不同气压水平暴露对小儿轮状病毒腹泻发病的影响, 为提高公众对于高气压暴露后的风险干预提供参考。方法通过中国传染病网络报告系统和中国气象科学数据共享服务网收集2012—2020年广州市小儿轮状病毒腹泻的每日发病数及同期气象数据, 利用分布滞后非线性模型(distributed lag non-linear models, DLNM)分析小儿轮状病毒腹泻发病与气压的关联, 进一步评估不同性别、年龄段人群在不同气压水平暴露后的风险。结果 2012—2020年累计报告小儿轮状病毒腹泻发病共18 587例, 其中男童11 662例(62.7%), 6~ < 24月龄儿童构成比最高(67.7%, 12 582例)。DLNM结果显示, 极端高气压天气暴露当天, 小儿轮状病毒腹泻发病风险最高(RR=1.50, 95%CI=1.24~1.82, P < 0.05), 且影响可持续28 d; 低气压的暴露后2周内对小儿轮状病毒腹泻发病风险较低(P值均 < 0.05)。极端高压天气期间, 女童的发病风险(RR=3.31, 95%CI=1.46~7.49, P < 0.05)高于男童(RR=1.98, 95%CI=0.96~4.07, P>0.05)。不同年龄亚组中, 在所观测气压最大值暴露后, 24~ < 60月龄儿童发病风险最高(RR=3.36, 95%CI=1.27~8.89, P < 0.05)。结论广州高气压的暴露会增加小儿轮状病毒腹泻发病风险。未来应提高公众对于高气压暴露后的风险意识。
- 轮状病毒属 /
- 腹泻 /
- 发病率 /
- 儿童
Abstract: Objective To explore the relative risks of rotavirus diarrhea after exposure to different levels of atmospheric pressure in children in Guangzhou City, so as to provide reference for improving public awareness of high atmospheric pressure exposure. Methods The study used the China Notifiable Communicable Diseases Network System and China Meteorological Science Data Sharing Service Network to collect meteorological data and data relating to daily cases of rotavirus diarrhea in children at Guangzhou Women and Children's Medical Center from 2012 to 2020. The association between rotavirus diarrhea and atmospheric pressure was analyzed using distributed lag non-linear models (DLNM). The relative risks of different sex and age sub-groups exposed to different atmospheric pressures were also evaluated. Results A total of 18 587 cases of rotavirus diarrhea were reported from 2012 to 2020, among which 11 662 cases (62.7%) were boys, and 12 582 cases (67.7%) were children aged 6 to 24 months old, which represented the highest proportion. The results of the DLNM showed that the relative risk of rotavirus diarrhea was the highest on the day of exposure to extreme high atmospheric pressure (RR=1.50, 95%CI=1.24-1.82, P < 0.05) and the effect could last for 28 days. Risk of rotavirus diarrhea was low for exposure to low pressure within 2 weeks (P < 0.05). During extremely high atmospheric pressure weather, RR was higher in girls (RR=3.31, 95%CI=1.46-7.49, P < 0.05) than that in boys (RR=1.98, 95%CI=0.96-4.07, P>0.05). Among different age sub-groups, RR was the highest in children aged 24 to 60 months after exposure to the highest level of atmospheric pressure exposure (RR=3.36, 95%CI=1.27-8.89, P < 0.05). Conclusion In Guangzhou, exposure to high pressure increases the risk of rotavirus diarrhea in children. In the future, public awareness should be raised regarding the risk after exposure to high atmospheric pressure.
- Rotavirus /
- Diarrhea /
- Incidence /
- Child
注释:

1) 利益冲突声明 所有作者声明无利益冲突。

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图 1 广州市2012—2020年小儿轮状病毒腹泻日病例数折线图

Figure 1. Line chart of daily cases of rotavirus diarrhea among children from Guangzhou during 2012 to 2020

下载: 全尺寸图片幻灯片

图 2 高、低位气压暴露对小儿轮状病毒腹泻发病影响

Figure 2. The impact of high and low atmospheric pressure exposure on the incidence of rotavirus diarrhea in children

下载: 全尺寸图片幻灯片

图 3 不同气压暴露对不同年龄儿童轮状病毒腹泻发病影响

Figure 3. The impact of different atmospheric pressure exposure on the incidence of rotavirus diarrhea of different age children

下载: 全尺寸图片幻灯片

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