运动结合饮食干预对肥胖非酒精性脂肪肝女大学生身体成分和脂代谢及肠道菌群的影响

王鹏; 刘宝亮; 刘岩; 蒋狄

doi:10.16835/j.cnki.1000-9817.2023.08.011

运动结合饮食干预对肥胖非酒精性脂肪肝女大学生身体成分和脂代谢及肠道菌群的影响

doi: 10.16835/j.cnki.1000-9817.2023.08.011

王鹏¹,
刘宝亮^1, ,,
刘岩²,
蒋狄³

1.
福建船政交通职业学院体育教研部, 福州 350007
2.
北京大学人民医院运营管理处
3.
河北医科大学中西医结合学院

基金项目:

福建省教育教学改革研究课题重点项目 GA2021019

详细信息

作者简介:
王鹏(1985-), 女, 山东青岛人, 硕士, 副教授, 主要研究方向为运动与健康

通讯作者:
刘宝亮, E-mail: 158586903@qq.com

利益冲突声明 所有作者声明无利益冲突。
中图分类号: R723.14 G806 G804.49
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- 被引次数: 0
出版历程
- 收稿日期: 2023-04-07
- 修回日期: 2023-06-12
- 网络出版日期: 2023-08-26
- 刊出日期: 2023-08-25

Effects of different intensity of exercise combined with dietary intervention on body composition, lipid metabolism and gut microbiota in obese nonalcoholic fatty liver disease female college students

1.
Department of Physical Culture, Fujian Chuanzheng Communications College, Fuzhou (350007), China

摘要

摘要: 目的了解不同强度运动结合饮食干预对肥胖非酒精性脂肪肝(nonalcoholic fatty liver disease, NAFLD)女大学生身体成分、脂代谢及肠道菌群的影响, 为改善肥胖NAFLD女大学生的健康水平提供理论依据。方法 2022年3—4月通过网上发布通知及选取体育保健班学生和至福建船政交通职业学院健康体检中心体检的43名肥胖NAFLD女大学生, 随机分为高等强度间歇训练(HIIT)组(n=22)及中等强度持续训练(MICT)组(n=21)。HIIT组实施8周HIIT结合饮食干预, MICT组实施8周MICT结合饮食干预, 对比干预前后肥胖NAFLD女大学生身体成分、脂代谢及肠道菌群指标的变化情况。结果干预8周后, HIIT和MICT结合饮食干预均能降低肥胖NAFLD女大学生体重、体质量指数(BMI)、体脂肪量、躯干脂肪量、腰臀比及内脏脂肪面积(t值分别为15.56, 15.48, 15.74, 13.92, 6.51, 11.55;13.64, 13.48, 15.82, 6.53, 4.40, 9.53), 血清胆固醇、三酰甘油及低密度脂蛋白水平及大肠杆菌和肠球菌指标均下降(t值分别为6.75, 2.16, 6.86, 3.06, 7.85;3.55, 2.36, 4.00, 3.32, 5.94), 有益菌乳酸杆菌及双歧杆菌指标增加(t值分别为6.64, 5.89;5.11, 4.71), 仅HIIT组高密度脂蛋白水平增加(t=5.08)(P值均 < 0.05);HIIT组除体脂肪量、躯干脂肪量、内脏脂肪面积及胆固醇水平低于MICT组外(t值分别为2.20, 2.10, 2.15, 2.26, P值均 < 0.05), 其他指标两组间差异均无统计学意义(P值均>0.05)。结论 HIIT及MICT结合饮食干预均使肥胖NAFLD女大学生身体成分、脂代谢及肠道菌群产生有益的变化, 但HIIT结合饮食干预在减少体脂肪及内脏脂肪量和改善脂质代谢方面效果更优。
- 运动活动 /
- 膳食 /
- 干预性研究 /
- 脂肪肝 /
- 身体成分 /
- 脂类代谢 /
- 学生
Abstract: Objective To understand the effects of different intensity of exercise combined with dietary intervention on body composition, lipid metabolism and gut microbiota in obese (nonalcoholic fatty liver disease, NAFLD) college students, so as to provide a theoretical reference for improving the health of the obese NAFLD female college students. Methods From March to Aprial 2022, 43 NAFLD female college students were recruited and randomly divided into HIIT group (n=22) and MICT group(n=21). Subsequently, HIIT group received HIIT combined with diet intervention for 8 weeks and MICT group received MICT combined with diet intervention for 8 weeks, the changes of body composition, lipid metabolism and gut microbiota in NAFLD female college students were compared before and after intervention. Results Compared with that before the experiment, after 8 weeks of HIIT and MICT combined with dietary intervention, the weight, BMI, body fat mass, trunk fat mass, waist hip ratio and visceral fat area significantly decreased (t=15.56, 15.48, 15.74, 13.92, 6.51, 11.55; 13.64, 13.48, 15.82, 6.53, 4.40, 9.53), the levels of cholesterol and triglyceride and low density lipoprotein, bacillus coli and enterococcus significantly decreased (t=6.75, 2.16, 6.86, 3.06, 7.85; 3.55, 2.36, 4.00, 3.32, 5.94); lactobacillus and bifidobacterium increased significantly (t=6.64, 5.89; 5.11, 4.71); however, only HIIT group had a significant increase in the level of high density lipoprotein(t=5.08)(P < 0.05). Compared with MICT group, body fat mass, trunk fat mass, visceral fat area and cholesterol level in HIIT group were significantly lower than those in MICT group (t=2.20, 2.10, 2.15, 2.26, P < 0.05). There were no significant differences in other indicators between the two groups (P > 0.05). Conclusion The results show that HIIT and MICT have benefical effects on body composition, lipid metabolism and gut microbiota in obese NAFLD female college students, but HIIT is superior to MICT intervention in reducing body fat mass, visceral fat and improving lipid metabolism.
- Motor activity /
- Diet /
- Intervention studies /
- Fatty liver /
- Body composition /
- Lipid metabolism /
- Students
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表 1 不同组别肥胖NAFLD女大学生干预前后身体成分指标比较(x±s)

Table 1. Comparison of the body composition in obese NAFLD female college students before and after interventions among different groups(x±s)

组别	干预前后	人数	统计值	体重/kg	BMI/(kg·m^-2)	体脂肪量/kg	躯干脂肪量/kg	腰臀比	内脏脂肪面积/cm²
HIIT组	干预前	22		76.92±2.78	29.59±1.15	29.20±1.71	16.08±1.39	0.89±0.05	115.32±4.30
	干预后	22		72.32±3.04	27.82±1.25	25.24±2.28	13.07±1.65	0.83±0.04	106.50±5.06
			t值	15.56	15.48	15.74	13.92	6.51	11.55
			P值	＜0.01	＜0.01	＜0.01	＜0.01	＜0.01	＜0.01
MICT组	干预前	21		77.81±2.06	30.25±1.44	29.69±1.93	16.36±1.48	0.88±0.02	116.05±4.95
	干预后	21		73.80±2.29	28.69±1.47	26.65±1.90	14.35±2.27	0.85±0.04	109.90±5.31
			t值	13.64	13.48	15.82	6.53	4.40	9.53
			P值	＜0.01	＜0.01	＜0.01	＜0.01	＜0.01	＜0.01

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表 2 不同组别肥胖NAFLD女大学生干预前后脂代谢指标和肠道菌群指标比较(x±s)

Table 2. Comparison of the lipid metabolism and the gut microbiota in obese NAFLD female college students before and after the interventions among different groups(x±s)

组别	干预前后	人数	统计值	脂代谢指标/(mmol·L^-1)				肠道菌群指标/(lg CFU·g^-1)
组别	干预前后	人数	统计值	TC	TG	HDL	LDL	肠球菌	大肠杆菌	乳酸杆菌	双歧杆菌
HIIT组	干预前	22		5.41±0.95	2.08±0.70	1.16±0.17	3.44±0.40	7.92±0.93	9.25±1.38	6.14±1.04	6.72±1.17
	干预后	22		4.15±0.62	1.94±0.59	1.25±0.13	2.94±0.31	7.04±0.97	8.68±1.28	7.00±0.84	7.28±0.99
			t值	6.75	2.16	-5.08	6.86	7.85	3.06	-6.64	-5.89
			P值	＜0.01	0.04	＜0.01	＜0.01	＜0.01	＜0.01	＜0.01	＜0.01
MICT组	干预前	21		5.24±1.01	2.11±0.50	1.14±0.26	3.39±0.51	7.73±0.85	9.09±1.48	6.44±0.89	6.65±1.18
	干预后	21		4.60±0.69	2.02±0.46	1.20±0.28	3.02±0.55	7.26±1.06	8.60±1.32	7.01±0.81	7.01±1.03
			t值	3.55	2.36	-2.02	4.00	-5.94	-3.32	-5.11	-4.71
			P值	＜0.01	0.03	0.06	＜0.01	＜0.01	＜0.01	＜0.01	＜0.01

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