The impact of health-related quality of life for children and adolescents aged 8-15 years in Nanjing
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摘要:
目的 探究南京市8~15岁儿童青少年的健康相关生命质量(HRQoL)受新冠病毒感染和健康相关行为的影响情况,为改善儿童青少年HRQoL提供理论依据。 方法 于2022年12月—2023年1月,采用多阶段随机整群抽样方法选取南京市2 398名8~15岁小学三年级至初中三年级学生,由学生自主完成HRQoL的中文版儿童版三水平欧洲五维生命质量测定量表(EQ-5D-Y-3L),家长协助完成其余部分的调查。 结果 新冠病毒正感染者的欧洲生命质量(EQ)-指数和视觉模拟量表(VAS)得分均低于未感染者和曾感染者(P值均 < 0.05)。正感染者报告存在“疼痛或不舒服”的比例大于未感染者和曾感染者,正感染者和曾感染者报告“行动能力”有困难的比例均高于未感染者(P值均 < 0.05)。缺少父母陪伴(OR=10.19,95%CI=3.12~33.22)、不规律早餐摄入(OR=10.63,95%CI=3.20~35.25)、屏幕时间过长(OR=8.24,95%CI=3.02~22.51)使正感染者存在“行动能力”有困难的风险增加(P值均 < 0.05)。不规律早餐摄入(OR=1.93,95%CI=1.31~2.84)和含糖饮料及零食摄入(OR=1.56,95%CI=1.17~2.10)加大曾感染者EQ-指数低于未感染者的风险;含糖饮料及零食摄入(OR=1.57,95%CI=1.21~2.05)和屏幕时间过长(OR=1.49,95%CI=1.12~1.98)使曾感染者VAS得分低于未感染者的风险增加(P值均 < 0.05)。 结论 新冠病毒感染会损害儿童青少年的HRQoL,不良健康行为会加重其负面影响。应提倡保持健康的行为和生活方式,减少新冠病毒感染对HRQoL的影响。 Abstract:Objective To investigate the impact of COVID-19 infection and health-related behaviors on the health-related quality of life of children and adolescents aged 8-15 years in Nanjing, so as to provide a theoretical basis for improving HRQoL in children and adolescents. Methods From December 2022 to January 2023, a total of 2 398 students aged 8-15 years from the third grade of primary school to junior middle school in Nanjing were selected by multistage random cluster sampling. The 3-level EuroQol 5-dimension Questionnaire Youth Vension (EQ-5D-Y-3L) was completed by the respondents on their own, and the parents assisted in completing the rest of the questionnaire. Results The EuroQol-index(EQ-index) and Visual Analogue Scale (VAS) scores of being infected individuals were lower than those of uninfected and previously infected (P < 0.05). The proportion of being infected individuals reporting difficulty on "Pain/Discomfort" was higher than that of uninfected and previously infected individuals, and the proportion of reporting difficulty on "Mobility" was also higher than that of uninfected individuals (P < 0.05). Lack of parental companionship(OR=10.19, 95%CI=3.12-33.22), irregular breakfast consumption (OR=10.63, 95%CI=3.20-35.25), and excessive screen time (OR=8.24, 95%CI=3.02-22.51) increased the risk of difficulty on "Mobility" in being infected individuals (P < 0.05). Irregular breakfast consumption (OR=1.93, 95%CI=1.31-2.84) and consumption of sweetened beverages and snacks (OR=1.56, 95%CI=1.17-2.10) increased the risk of having lower EQ-index in previously infected individuals compared to uninfected individuals. Furthermore, consumption of sweetened beverages and snacks (OR=1.57, 95%CI=1.21-2.05) and excessive screen time (OR=1.49, 95%CI=1.12-1.98) also increased the risk of VAS scores being lower in previously infected individuals compared to uninfected individuals (P < 0.05). Conclusion The COVID-19 infection impairs HRQoL, and unhealthy behaviors deteriorate its negative impact. Healthy behaviors and lifestyles should be advocated to reduce the impact of COVID-19 infection on HRQoL. -
Key words:
- Health behavior /
- Health-related quality of life /
- Regression analysis /
- Students
1) 利益冲突声明 所有作者声明无利益冲突。 -
表 1 不同新冠病毒感染状态儿童青少年健康相关行为分布
Table 1. Distribution of HRB among children and adolescent with different COVID-19 infections status
组别 人数 吃早餐 每周快餐摄入次数 每周含糖饮料和零食摄入次数 中高等强度身体活动时长/(h·d-1) 屏幕时间/(h·d-1) 每周户外运动次数 每天 非每天 < 1次 ≥1次 < 1次 ≥1次 ≥1 < 1 < 2 ≥2 >3次 ≤3次 未感染 1 073 917(85.46) 156(14.54) 917(85.46) 156(14.54) 405(37.74) 668(62.26) 68(6.34) 1 005(93.66) 725(67.57) 348(32.43) 912(85.00) 161(15.00) 曾感染 1 053 910(86.42) 143(13.58) 941(89.36) 112(10.64) 468(44.44) 585(55.56) 72(6.84) 981(93.16) 742(70.47) 311(29.53) 857(81.39) 196(18.61) 正感染 272 237(87.13) 35(12.87) 233(85.66) 39(14.34) 102(37.50) 170(62.50) 17(6.25) 255(93.75) 177(65.07) 95(34.93) 219(80.51) 53(19.49) 合计 2 398 2 064(86.07) 334(13.93) 2 091(87.20) 307(12.80) 975(40.66) 1 423(59.34) 157(6.55) 2 241(93.45) 1 644(68.56) 754(31.44) 1 988(82.90) 410(17.10) 注: ()内数字为构成比/%。 表 2 不同新冠病毒感染状态儿童青少年健康相关生命质量表现分布
Table 2. Distribution of HRQoL among children and adolescents with different COVID-19 infectious status
组别 人数 MO SC UA PD AD 没有困难 有些困难 有很大困难 没有困难 有些困难 有很大困难 没有困难 有些困难 有很大困难 没有困难 有些困难 有很大困难 没有困难 有些困难 有很大困难 未感染 1 073 1 058(98.60) 14(1.30) 1(0.10) 1 046(97.48) 26(2.42) 1(0.10) 986(91.89) 83(7.74) 4(0.37) 948(88.35) 123(11.46) 2(0.19) 938(87.42) 126(11.74) 9(0.84) 曾感染 1 053 1 020(96.87) 28(2.66) 5(0.47) 1 025(97.34) 26(2.47) 2(0.19) 960(91.17) 91(8.64) 2(0.19) 926(87.94) 123(11.68) 4(0.38) 900(85.47) 150(14.25) 3(0.28) 正感染 272 260(95.59) 11(4.04) 1(0.37) 261(95.96) 10(3.67) 1(0.37) 250(91.91) 21(7.72) 1(0.37) 222(81.62) 49(18.01) 1(0.37) 227(83.46) 40(14.70) 5(1.84) 合计 2 398 2 338(97.50) 53(2.21) 7(0.29) 2 332(97.25) 62(2.59) 4(0.16) 2 196(91.58) 195(8.13) 7(0.29) 2 096(87.41) 295(12.30) 7(0.29) 2 065(86.11) 316(13.18) 17(0.71) 注: ()内数字为构成比/%。 表 3 健康相关行为对是否感染新冠病毒儿童青少年生命质量影响的Logistic回归分析[OR值(95%CI)]
Table 3. Logistic regression analysis of the impact of HRB on HRQoL of children and adolescents controlled by COVID-19 infectious status[OR(95%CI)]
自变量 选项 EQ-指数 VAS得分 曾感染 正感染 曾感染 正感染 早餐摄入 每天 1.00 1.00 1.00 1.00 非每天 1.93(1.31~2.84)** 2.52(1.13~5.61)* 1.32(0.90~1.93) 1.64(0.75~3.59) 每周快餐摄入次数/次 <1 1.00 1.00 1.00 1.00 ≥1 1.14(0.73~1.78) 1.23(0.56~2.69) 1.33(0.88~2.00) 1.00(0.47~2.13) 每周含糖饮料及零食摄入次数/次 <1 1.00 1.00 1.00 1.00 ≥1 1.56(1.17~2.10)** 0.75(0.42~1.36) 1.57(1.21~2.05)** 1.70(0.97~2.96) 中到高等强度身体活动/(h·d-1) ≥1 1.00 1.00 1.00 1.00 <1 1.53(0.83~2.84) 1.84(0.54~6.24) 1.31(0.77~2.27) 1.12(0.34~3.40) 屏幕时间/(h·d-1) <2 1.00 1.00 1.00 1.00 ≥2 1.18(0.86~1.61) 0.88(0.47~1.63) 1.49 (1.12~1.98)** 1.79(1.00~3.14) 每周户外活动次数/次 >3 1.00 1.00 1.00 1.00 ≤3 0.77(0.53~1.12) 0.70(0.34~1.43) 0.93(0.66~1.30) 0.56(0.29~1.11) 注:调整了社会人口学因素(性别、年级、是否为独生子女、BMI、父母户籍、父母教育水平、父母婚姻状态、家庭平均月收入、常陪伴成员及其就业状态);*P < 0.05,**P < 0.01。 -
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