紫光与近视关联的研究进展

徐星; 许韶君; 梁莉; 陶芳标

doi:10.16835/j.cnki.1000-9817.2023.05.032

紫光与近视关联的研究进展

doi: 10.16835/j.cnki.1000-9817.2023.05.032

徐星¹,
许韶君^1, ,,
梁莉²,
陶芳标¹

1.
安徽医科大学公共卫生学院儿少卫生与妇幼保健学系/出生人口健康教育部重点实验室，合肥 230032
2.
中国科学技术大学附属第一医院(安徽省立医院)眼科

基金项目:

国家重点研发计划 2021YFC2702102

国家重点研发计划 2021YFC2702105

详细信息

作者简介:
徐星(1996-)，女，浙江绍兴人，在读硕士，主要研究方向为儿童青少年卫生

通讯作者:
许韶君，E-mail：xushaojun@ahmu.edu.cn

利益冲突声明 所有作者声明无利益冲突。
中图分类号: R778.1⁺¹ R179
计量
- 文章访问数: 704
- HTML全文浏览量: 335
- PDF下载量: 120
- 被引次数: 0
出版历程
- 收稿日期: 2023-03-21
- 修回日期: 2023-04-05
- 网络出版日期: 2023-05-25
- 刊出日期: 2023-05-25

Research progress on the association between violet light and myopia

1.
Department of Maternal, Child & Adolescent Health, School of Public Health/MOE Key Laboratory of Population Health across Life Cycle, Anhui Medical University, Hefei(230032), China

摘要

摘要: 近视已经成为全球性的重要公共卫生问题，户外活动对近视保护作用的本质原因可能是户外光线的暴露，越来越多的研究关注光谱对眼健康的影响。有研究发现紫光可能对近视具有保护作用，但两者之间的关联机制尚未明确。文章就紫光与近视防控的关联及其可能机制作出综述，为进一步探索紫光防控近视的作用提供参考。
- 光 /
- 波长 /
- 近视 /
- 研究
Abstract: Myopia has become a major global public health problem. Exposure to outdoor light may explain the protective effect of outdoor activities on myopia. Currently, a growing number of studies focus on the effects of the spectrum on eye health. Recent studies have found that violet light may have a protective effect on myopia, but the mechanism of action between violet light and myopia is not yet fully understood. The paper reviews the association between violet light and myopia prevention and control, and the possible mechanisms of violet light and myopia to provide a reference value for further exploration of the role of violet light on myo-pia.
- Light /
- Wave length /
- Myopia /
- Research
注释:

1) 利益冲突声明 所有作者声明无利益冲突。

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表 1 纳入文献相关信息

Table 1. Information of included literature

第一作者与年份	国家	研究方法	样本量	研究对象	研究结果
Torii(2017)^[8]	日本	①实验研究 ②临床试验	39只/ 147名	雏鸡/13~18岁近视学生	(1)与对照组相比，接受VL照射的小鸡遮盖眼屈光度变化更小(-4.59，-15.18 D)；(2)与对照组相比，佩戴VL透射的隐形眼镜学生AL变化更小(0.14，0.19 mm)。
Torii(2017)^[14]	日本	队列研究	26名	年龄＞25周岁的高度近视患者	与对照组相比，植入VL透射的人工晶状体5年内的屈光度和AL变化更小(-0.49，-1.09 D；0.09，0.38 mm)。
Wang(2018)^[9]	中国德国	实验研究	77只	雏鸡	雏鸡在VL暴露5 d时形觉剥夺眼近视进展少于WL暴露组(-5.07，-7.88 D)，前房深度夜更短[(0.96±0.018)(1.04±0.031)mm]。
Ofuji(2020)^[15]	日本	病例报告	1名	患有屈光参差性弱视的4岁男童	该儿童在佩戴VL透射框架眼镜的2年里，右眼和左眼的AL、脉络膜厚度和屈光度变化分别为(+0.85，-0.20 mm；+4.9，+115.7 μm；-1.02，+1.88 D)。
Strickland(2020)^[16]	美国	实验研究	93只	小鼠	在野生小鼠中，与暴露在WL下的小鼠相比，短波长VL诱导了远视且抑制了近视；在视网膜锥细胞失功能小鼠模型中，VL不会诱导远视或抑制近视。
Mori(2021)^[17]	日本	临床试验	113名	6~12岁近视儿童	在24个月时，佩戴VL透射框架眼镜儿童调整后AL变化平均值小于对照组；其调整后SE变化平均值小于对照组，但无统计学意义。
Kobashi(2021)^[18]	日本	临床试验	20名	年龄≥15周岁角膜扩张症患者	在基线前1年和6个月观测期间，角膜最大曲率的平均变化分别为(6.03±3.41)D和(-0.81±3.34)D。
Jiang(2021)^[10]	日本	实验研究	40只	小鼠	与绿光(green light, GL)，RL，BL相比，VL显著抑制了小鼠屈光变化和AL增长。
Torii(2022)^[19]	日本	临床试验	43名	6~12岁近视儿童	与对照组相比，佩戴发射VL框架眼镜的儿童屈光度、AL、脉络膜厚度变化均有统计学意义。
Jeong (2023)^[11]	日本	实验研究	39只	小鼠	70%和100% VL透过率晶状体诱导的小鼠近视眼较40% VL透过率晶状体诱导的小鼠近视眼近视进展程度更少，AL增长的抑制作用更明显，脉络膜增厚更明显。

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参考文献(25)

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