长期配戴角膜塑形镜对青少年视觉质量及细菌感染发生的影响

靳慧霞; 陈霞

doi:10.16835/j.cnki.1000-9817.2022.12.021

长期配戴角膜塑形镜对青少年视觉质量及细菌感染发生的影响

doi: 10.16835/j.cnki.1000-9817.2022.12.021

靳慧霞,
陈霞^,

河南省直第三人民医院眼科，郑州 450053

详细信息

作者简介:
靳慧霞(1981-)，女，河南省人，硕士，主治医师，主要研究方向为眼视光

通讯作者:
陈霞，E-mail：chenxia5260@163.com

利益冲突声明 所有作者声明无利益冲突。
中图分类号: R179 R778.3 R446
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- 被引次数: 0
出版历程
- 收稿日期: 2022-08-12
- 修回日期: 2022-09-05
- 网络出版日期: 2022-12-30
- 刊出日期: 2022-12-25

Effects of orthokeratology lens on visual quality and bacterial infection in adolescents

JIN Huixia,
CHEN Xia^,

Department of Ophthalmology, Henan No.3 Provincial People's Hospital, Zhengzhou(450053), China

摘要

摘要: 目的探讨青少年长期配戴角膜塑形镜后对视觉质量和细菌感染发生率的影响，为促进青少年用眼卫生提供参考。方法收集前往河南省直第三人民医院定期复查的280例配戴角膜塑形镜的青少年作为研究对象，分别在佩戴前、配戴6个月、配戴1年时间点对患者进行眼部专科检查、视觉质量分析系统(Optical Quality Analysis System Ⅱ, OQAS-Ⅱ)客观视觉质量测评和眼部菌群检查，比较青少年配戴角膜塑形镜前后视觉质量和眼部菌群的变化。结果与配戴角膜塑形镜之前青少年的斯特烈尔比，调制传递函数，9%OV、20%OV、100%OV分别为(0.18±0.04，33.21±4.23，0.72±0.12，0.99±0.19，1.32±0.21)，青少年配戴6个月和配戴1年后患者的斯特烈尔比(0.21±0.05，0.24±0.03)和调制传递函数(37.65±5.29，39.01±3.94)均升高，9%客观视力(0.61±0.10，0.53±0.26)、20%客观视力(0.82±0.21，0.78±0.15)和100%客观视力(1.10±0.13，1.00±0.07)均降低，差异均有统计学意义(F值分别为7.89，6.59，6.52，9.47，8.49，P值均＜0.05)，而客观散射指数配戴前后(0.99±0.21，1.01±0.07，1.23±0.31)差异无统计学意义(F=-1.56，P＞0.05)。与配戴角膜塑形镜前相比，佩戴后患者的细菌感染发生率显著提高(P值均＜0.05)，配戴角膜塑形镜1年的患者铜绿假单胞菌感染率升至0.36%，大肠埃希菌感染率高达0.71%，金黄色葡萄球菌感染率高至0.36%。结论青少年长期配戴角膜塑形镜可有效改善视觉质量，但也会提高细菌感染发生率，需要临床上做好针对青少年的用眼卫生教育。
- 角膜塑形术 /
- 眼镜 /
- 细菌 /
- 感染 /
- 青少年
Abstract: Objective To investigate the effects of orthokeratology on visual quality and incidence of bacterial infection in adolescents. Methods A total of 280 orthokeratology teenage patients were selected. Visual examination, OQAS-Ⅱ optical assessment and ocular flora were assessed before, 6 months and 1-year after orthokeratology wearing. Changes in visual and optical performance and ocular flora infection were compared. Results Compared with before wearing orthokeratography lens (0.18±0.04, 33.21±4.23, 0.72±0.12, 0.99±0.19, 1.32±0.21), parameters of adolescent patients including strayers ratio (0.21±0.05, 0, 24±0.03) and modulation transfer cutoff (37.65±5.29, 39.01±3.94) increased after wearing for 6 months and 1 year, 9% objective visual acuity(0.61±0.10, 0.53±0.26), 20% objective visual acuity (0.82±0.21, 0.78±0.15) and 100% objective visual acuity (1.10±0.13, 1.00±0.07) decreased, the differences were statistically significant (F=7.89, 6.59, 6.52, 9.47, 8.49, P < 0.05), while the objective scattering index index (0.99±0.21, 1.01±0.07, 1.23±0.31) had no significant difference before and after wearing orthokeratography lens (F=-1.56, P>0.05). Compared with before wearing, the incidence of bacterial infection significantly increased after wearing (P < 0.05). The infection rate of pseudomonas aeruginosa in patients who wore orthokeratology lens for 1 year rose to 0.36%, e. coli infection rates as high as 0.71%, staphylococcus aureus infection rates as high as 0.36%. Conclusion Long-term orthokeratology lens wear can effectively improve the visual quality of adolescents, but also increase the risk of bacterial infection. Timely awareness on good eye hygiene practice should be emphasized to the users.
- Orthokeratologic procedures /
- Eyeglasses /
- Bateria /
- Infection /
- Adolescent
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表 1 配戴角膜塑形镜前后青少年视觉质量比较(x±s，n=280)

Table 1. Comparison of visual quality before and after wearing orthokeratology lens(x±s, n=280)

配戴时间	SR	MTF cutoff/(c·deg^-1)	OSI	9%OV	20%OV	100%OV
配戴前	0.18±0.04	33.21±4.23	0.99±0.21	0.72±0.12	0.99±0.19	1.32±0.21
配戴6月	0.21±0.05	37.65±5.29	1.01±0.07	0.61±0.10	0.82±0.21	1.10±0.13
配戴1年	0.24±0.03	39.01±3.94	1.23±0.31	0.53±0.26	0.78±0.15	1.00±0.07
F值	7.89	6.59	-1.56	6.52	9.47	8.49
P值	0.01	0.02	0.62	0.02	< 0.01	< 0.01

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