Correlation between the changes of caries activity and new caries in 3 years old caries-free children after 1 year intervention
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摘要:
目的 观察无龋3岁儿童干预1年后龋活性变化与新龋发生情况的关系,为今后龋病的分级管理提供参考依据。 方法 2020年9月基线时选择张家港市9所幼儿园的808名无龋3岁儿童为研究对象,进行口腔检查和龋活性检测,高龋活性组3个月涂氟1次,中、低龋活性组6个月涂氟1次,干预1年后,2021年9月对714名儿童再次进行口腔检查和龋活性检测,分析不同龋活性变化组间儿童新增患龋情况的差异。 结果 干预1年后新增患龋儿童200名,新龋发生率28.0%,龋均为0.0(0.0, 1.0)。男女童患龋率分别是22.5%,34.1%,龋均分别为0.0(0.0, 0.0),0.0(0.0±1.0),女童的患龋率和龋均高于男童,差异均有统计学意义(χ2/Z值分别为11.83,3.61,P值均 < 0.05)。龋活性不变、降低、升高3组间的新龋发生率分别为29.6%,14.3%,35.6%;龋均分别为0.0(0.0,1.0),0.0(0.0, 0.0),0.0(0.0, 1.0),3组间差异均有统计学意义(χ2/Z值分别为20.68,21.04,P值均 < 0.05)。涂氟干预会影响龋活性变化,随着干预次数的增加,龋活性降低的人群占比升高,差异有统计学意义(χ2=80.55,P < 0.05)。但不同干预频率组间新龋发生率和龋均的差异无统计学意义(χ2/Z值分别为0.83,0.61,P值均>0.05)。 结论 龋活性降低可以减少新龋发生率,增加涂氟干预频率可降低龋活性。 Abstract:Objective To observe the relationship between the changes of caries activity and the incidence of new caries in 3 years old caries-free children after 1 year of intervention, and to provide reference for grading management of caries. Methods At baseline in September 2020, 808 caries-free 3-year-old children from 9 kindergartens in Zhangjiagang were selected for oral examination and caries activity detection. After one year of fluoride treatment, fluoride was applied once every 3 months in the high caries activity group and once every 6 months in the moderate and low caries activity groups, a total of 714 caria-free children aged 3 years were followed up for oral examination and caries activity detection in September 2021. The differences of new caries in different caries activity changes groups were analyzed. Results There were 200 new caries (28.0%) and dmft was 0.0(0.0, 1.0). The prevalence of caries (34.1%) and dmft 0.0(0.0, 0.0) in girls were higher than in boys(22.5%)[0.0(0.0, 1.0)], the differences were statistically significant(χ2/Z=11.83, 3.61, P < 0.05). The incidence of new caries among unchanged, decreased and increased of caries activity group was 29.6%, 14.3% and 35.6%, respectively. The average number of dmft was 0.0(0.0, 1.0), 0.0(0.0, 0.0), 0.0(0.0, 1.0), respectively. There were significant differences in the incidence of new caries and dmft among the three groups(χ2/Z=20.68, 21.04, P < 0.05). Fluorinated intervention could affect the changes of caries value. With the increase of the number of interventions, the proportion of children with reduced caries activity increased(χ2=80.55, P < 0.05). However, there were no significant differences in the incidence of new caries and dmft among groups with different intervention frequencies(χ2/Z=0.83, 0.61, P < 0.05). Conclusion Reduction of caries activity through fluoride application could be future approach for caries control among children. -
Key words:
- Dental caries /
- Incidence /
- Intervention studies /
- Child, preschool
1) 利益冲突声明 所有作者声明无利益冲突。 -
表 1 不同干预频率儿童龋活性变化及新发龋检出率
Table 1. Changes of caries activity and new caries in children with different intervention frequencies
1年干预次数 人数 龋活性变化 新发龋 不变 降低 升高 1次 71 27(38.0) 14(19.7) 30(42.3) 20(28.2) 2次 514 256(49.8) 86(16.7) 172(33.5) 142(27.6) 3次 26 16(61.5) 10(38.5) 0 6(23.1) 4次 103 59(57.3) 44(42.7) 0 32(31.1) 合计 714 358(50.1) 154(21.6) 202(28.3) 200(28.0) 注: ()内数字为构成比或检出率/%。 -
[1] 第4次全国口腔健康流行病学调查技术组, 中华口腔医学会. 第4次全国口腔健康流行病学调查(2015—2018)工作手册[R]. 北京: 中华口腔医学会, 2015: 27-29.The 4th National Oral Health Epidemiological Investigation Technical Group of the PRC, Chinese Stomatological Association. Manual of the 4th national oral health epidemiological survey (2015-2018)[R]. Beijing: Chinese Stomatological Association, 2015: 27-29. (in Chinese) [2] 玄松玉, 袁峻伟, 王珏, 等. Cariostat龋易感性检测技术用于评价3岁儿童患龋风险的研究[J]. 中华口腔医学杂志, 2017, 52(11): 667-671. doi: 10.3760/cma.j.issn.1002-0098.2017.11.004XUAN S Y, YUAN J W, WANG J, et al. A 2-year cohort study on the caries risk assessment of 3-year-old caries-free children using Cariostat caries activity test[J]. Chin J Stomatol, 2017, 52(11): 667-671. (in Chinese) doi: 10.3760/cma.j.issn.1002-0098.2017.11.004 [3] 李庭庭. 天津市学龄前儿童乳牙患龋情况及龋病活跃性检测分析[J]. 临床口腔医学杂志, 2021, 37(10): 625-627. doi: 10.3969/j.issn.1003-1634.2021.10.015LI T T. Preschool children dental caries prevalence and caries activity test in Tianjin[J]. J Clin Stomatol, 2021, 37(10): 625-627. (in Chinese) doi: 10.3969/j.issn.1003-1634.2021.10.015 [4] 肖小芬, 何姗丹, 陈泳怡, 等. 不同龋敏感程度学龄前儿童的牙菌斑微生物群落研究[J]. 口腔疾病防治, 2019, 25(12): 763-768. doi: 10.12016/j.issn.2096-1456.2019.12.003XIAO X F, HE S D, CHEN Y Y, et al. Study on the plaque microbial community of preschool children with different caries sensitivity[J]. J Prev Treat Stomatol Dis, 2019, 25(12): 763-768. (in Chinese) doi: 10.12016/j.issn.2096-1456.2019.12.003 [5] 周庆楠, 尚佳健. 菌斑微生物群落构成变化与儿童龋病相关研究进展[J]. 口腔疾病防治, 2021, 29(4): 267-272. https://www.cnki.com.cn/Article/CJFDTOTAL-GDYB202104010.htmZHOU Q N, SHANG J J. Research progress on the relationship between the changes in microbial community composition of plaque and dental caries in children[J]. J Prev Treat Stomatol Dis, 2021, 29(4): 267-272. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-GDYB202104010.htm [6] RATHER S A, SHARMA S C, MAHMOOD A. PH dependent effects of sodium ions on dextransucrase activity in Streptococcus mutans[J]. Biochem Biophys Rep, 2019, 20: 100692. [7] 刘芸, 孟玉生, 杨秀巧. Cariostat龋易感性检测技术用于评估无龋儿童1年后患龋风险的研究[J]. 临床口腔医学杂志, 2022, 38(2): 104-107. https://www.cnki.com.cn/Article/CJFDTOTAL-LCKY202202011.htmLIU Y, MENG Y S, YANG X Q, et al. A one-year cohort study on the caries risk assessment of caries-free children using Cariostat caries activity test[J]. J Clin Stomatol, 2022, 38(2): 104-107. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-LCKY202202011.htm [8] 苗江霞, 邹晓璇, 王文红. 北京市海淀区1 713名0~2岁婴幼儿Cariostat龋易感性检测的研究[J]. 北京口腔医学, 2019, 27(5): 284-287. https://www.cnki.com.cn/Article/CJFDTOTAL-BJKX201905015.htmMIAO J X, ZOU X X, WANG W H, et al. Analysis of Cariostat caries activity tests in 1 713 infants 0-2-year-old infants in Haidian District Beijing[J]. Beijing J Stomatol, 2019, 27(5): 284-287. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-BJKX201905015.htm [9] 田芝娟, 施宏燕, 韩祥永. 2017~2021年上海市闵行区学龄前儿童口腔一级预防效果评价[J]. 口腔医学研究, 2022, 38(7): 650-653.TIAN Z J, SHI H Y, HAN X Y. Evaluation of effect of oral primary prevention for preschool children in Shanghai Minhang District during 2017-2021[J]. J Oral Sci Res, 2022, 38(7): 650-653. (in Chinese) [10] LI J B, FAN W, ZHOU Y, et al. The status and associated factors of early childhood caries among 3- to 5-year-old children in Guangdong, southern China: a provincial cross-sectional survey[J]. BMC Oral Health, 2020, 20(1): 265. doi: 10.1186/s12903-020-01253-w [11] MUNTEANU A, HOLBAN A M, PAUNA M R, et al. Review of professionally applied fluorides for preventing dental caries in children and adolescents[J]. Appl Sci Volum, 2022, 12(3): 1054. doi: 10.3390/app12031054 [12] MATSKIEVA O V, SKRIPKINA G I, SOLONENKO A P, et al. Influence of fluoride preparations for the prevention of dental caries on the enamel solubility[J]. Stomatologiia, 2021, 100(6): 13-16. doi: 10.17116/stomat202110006113 [13] BERNABÉ E, BALLANTYNE H, LONGBOTTOM C, et al. Early introduction of sugar-sweetened beverages and caries trajectories from age 12 to 48 months[J]. J Dent Res, 2020, 99(8): 898-906. doi: 10.1177/0022034520917398 [14] KHAN I M, MANI S A, DOSS J G, et al. Pre-schoolers' tooth brushing behaviour and association with their oral health: a cross sectional study[J]. BMC Oral Health, 2021, 21(1): 283. doi: 10.1186/s12903-021-01643-8 [15] NATAPOV L, DEKEL D, PIKOVSKY V, et al. Dental health of preschool children after two-years of a supervised tooth brushing program in Southern Israel[J]. Israel J Health Policy Res, 2021, 10(1): 42. [16] CORRÊA-FAKIA P, PAIXÃO-GONÇALVES S S, RAMOS-JORGE M L, et al. Developmental enamel defects are associated with early childhood caries: case-control study[J]. Int J Paediatr Dent, 2020, 30(1): 11-17. [17] 李骏, 王蕾, 杨艳, 等. 西安市局部用氟项目对5~6岁儿童早期龋病的影响[J]. 中国学校卫生, 2020, 41(5): 739-743. doi: 10.16835/j.cnki.1000-9817.2020.05.028LI J, WANG L, YANG Y, et al. Caries-inhibiting effect of topical fluorides for 5 to 6 years old children in two urban districts of Xi'an[J]. Chin J Sch Health, 2020, 41(5): 739-743. (in Chinese) doi: 10.16835/j.cnki.1000-9817.2020.05.028 -

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