中国青少年1990与2019年HIV/AIDS疾病负担性别差异

马晓梅; 王瑾瑾; 裴兰英; 黄艳梅; 杨梦利; 赵倩倩; 徐学琴; 闫国立

doi:10.16835/j.cnki.1000-9817.2022.10.032

中国青少年1990与2019年HIV/AIDS疾病负担性别差异

doi: 10.16835/j.cnki.1000-9817.2022.10.032

河南中医药大学医学院，郑州 450046

基金项目:

河南省高等学校重点科研项目 21A330003

河南省自然科学基金项目 202300410253

河南中医药大学科研苗圃 MP2022-05

详细信息

作者简介:
马晓梅(1988-)，女，河南周口人，讲师，硕士, 主要研究方向为流行病学与卫生统计学

通讯作者:
王瑾瑾，E-mail：wangjinjin@hactcm.edu.cn

闫国立，E-mail：13937187109@qq.com

利益冲突声明 所有作者声明无利益冲突。
中图分类号: R179 R512.91 R193
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- 被引次数: 0
出版历程
- 收稿日期: 2022-02-21
- 修回日期: 2022-07-22
- 网络出版日期: 2022-10-28
- 刊出日期: 2022-10-25

Gender disparities in epidemiological trend of HIV/AIDS disease burden among Chinese adolescents from 1990 to 2019

Henan University of Chinese Medicine School of Medcine, Zhengzhou(450046), China

摘要

摘要: 目的分析1990年与2019年中国10~24岁青少年人群HIV/AIDS疾病负担在性别中的变化，为制定针对该年龄层人群的有效干预措施提供信息。方法使用全球疾病负担(Global Burden of Disease，GBD)2019数据库资料，按性别和年龄提取1990—2019年中国10~24岁青少年人群因HIV/AIDS的死亡数和死亡率、伤残调整寿命年(DALY)、DALY率、过早死亡损失寿命年(YLL)、YLL率、伤残损失寿命年(YLD)、YLD率等指标来分析该群体HIV/AIDS疾病负担在性别中的变化幅度。结果 2019年，中国10~24岁青少年人群因HIV/AIDS的死亡数和死亡率、DALY、DALY率、YLL、YLL率、YLD与YLD率分别为847人、0.37/10万、62 621人年、27.51/10万、58 036人年、25.49/10万、4 584人年与2.01/10万，相比1990年增幅分别为401.18%，691.49%，370.48%，648.26%，409.53%，710.33%，138.87%与279.25%。2019年中国10~14，15~19岁与20~24岁男性因HIV/AIDS的死亡数和死亡率、DALY与DALY率均高于女性，与1990年相比，增幅均高于女性；10~14岁人群疾病负担增幅高于20~24岁。1990—2019年，随着年龄和年份的增加，青少年死亡率和DALY率的性别差距增大。结论与1990年相比，2019年中国10~24岁青少年人群HIV/AIDS感染风险持续增加，低龄HIV感染者增幅明显，性别差异日益明显。
- 获得性免疫缺陷综合征 /
- 人免疫缺陷病毒蛋白质类 /
- 疾病 /
- 性别分布 /
- 青少年 /
- 死亡率
Abstract: Objective To analysis gender disparities in epidemiological trend of HIV/AIDS disease burden among Chinese population aged 10-24 years from 1990 to 2019. Methods The Global Burden of Disease Study (GBD 2019) results tool was used to extract the number of deaths, mortality rate, disability adjusted life years (DALY), DALY rate, years of life lost (YLL), YLL rate, years lived with disability (YLD) and YLD rate to comprehensively analyze the change range of HIV/AIDS disease burden in the Chinese population aged 10-24 years from 1990 to 2019. Results In 2019, the number of deaths, mortality rate, DALY, DALY rate, YLL, YLL rate, YLD and YLD rate of Chinese population aged 10-24 years due to HIV/AIDS were 847, 0.37 per 100 000, 62 621 person years, 27.51 per 100 000, 58 036 person years, 25.49 per 100 000, 4 584 person years, 2.01 per 100 000 respectively, with the increase of 401.18%, 691.49%, 370.48%, 648.26%, 409.53%, 710.33%, 138.87% and 279.25%, compared with the data in 1990. In term of gender, the number of deaths, mortality rate, DALY, and DALY rate of Chinese male population aged 10-14, 15-19 and 20-24 years due to HIV/AIDS in 2019 were higher than those of female, and the growth rate (compared with 1990) was also higher than that of female. In term of the age group, the increase in people aged 10-14 years was higher than that of people aged 20-24 years. From 1990 to 2019, with the increase of year and age, gender disparity between mortality and DALY rate widened. Conclusions Compared with data in 1990, the risk of HIV/AIDS infection in 2019 among Chinese population aged 10-24 years continued to increase, especially among young people of 10-14 years. Gender disparity is exacerbating.
- Acquired immunodeficiency syndrome /
- Human immunodeficiency virus proteins /
- Disease /
- Sex distribution /
- Adolescent /
- Mortality
注释:

1) 利益冲突声明 所有作者声明无利益冲突。

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图 1 1990和2019年中国不同性别青少年人群HIV/AIDS疾病死亡率

Figure 1. Gender differences in HIV/AIDS disease burden among Chinese adolescents aged 10-24 in 1990 and 2019

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图 2 1990和2019年中国不同性别青少年人群HIV/AIDS疾病DALY率

Figure 2. Gender differences in HIV/AIDS disease burden among Chinese adolescents aged 10-24 in 1990 and 2019

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表 1 1990年与2019年中国不同性别青少年HIV/AIDS人群疾病负担

Table 1. Changes in disease burden of HIV/AIDS adolescents in China, in 1990 and 2019

性别	年份	死亡数	死亡率/10^-5	DALY/人年	DALY率/10^-5	YLL/人年	YLL率/10^-5	YLD/人年	YLD率/10^-5
男	1990	95	0.05	7 468	4.02	6 421	3.45	1 046	0.56
	2019	553	0.46	40 834	33.70	37 795	31.19	3 038	2.51
女	1990	74	0.04	5 842	3.32	4 969	2.82	873	0.50
	2019	294	0.28	21 787	20.46	20 241	19.01	1 546	1.45
合计	1990	169	0.05	13 310	3.68	11 390	3.15	1 919	0.53
	2019	847	0.37	62 621	27.51	58 036	25.49	4 584	2.01

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表 2 1990年与2019年中国不同年龄组不同性别青少年HIV/AIDS人群疾病负担

Table 2. Changes of disease burden of HIV/AIDS adolescents in China in different age groups and gender, in 1990 and 2019

年龄/岁	年份	死亡人数			死亡率/10^-5			DALY/人年			DALY率/10^-5
年龄/岁	年份	男性	女性	合计	男性	女性	合计	男性	女性	合计	男性	女性	合计
10~14	1990	2	1	3	0.01	0.01	0.01	137	91	228	0.26	0.18	0.22
	2019	45	36	81	0.12	0.10	0.11	3 618	2 807	6 425	9.44	8.68	9.09
15~19	1990	16	15	31	0.02	0.02	0.02	1316	1276	2592	2.02	2.07	2.04
	2019	116	73	189	0.29	0.21	0.25	8 941	5 685	14 626	22.30	16.22	19.47
20~24	1990	77	58	135	0.11	0.09	0.10	6 015	4 475	10490	8.89	6.92	7.92
	2019	392	185	577	0.92	0.47	0.70	28 275	13 295	41 570	66.11	34.00	50.78

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