Psychological and behavioral problems and associated factors in children with tic disorders
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摘要:
目的 研究抽动障碍儿童的心理行为问题及相关因素,为合理干预治疗提供依据。 方法 采用病例对照研究方法,选择2020年6月至2021年6月华中科技大学同济医学院附属同济医院儿科神经门诊就诊的69名抽动障碍(TD)儿童作为病例组,并按性别与年龄匹配同期69名非TD的正常儿童作为对照组,通过填写一般情况调查表、儿童焦虑性情绪筛查量表 41项(SCARED-41)、长处和困难问卷(SDQ-25)及儿童抑郁量表 10项(CDI-10)等,分析TD儿童的心理行为问题及相关因素。 结果 TD组与对照儿童组SCARED-41总分、SDQ-25总分及SDQ-25困难部分、CDI-10总分分别为(22.1±12.5,13.3±12.3)(21.1±6.0,15.9±3.4)(15.6±6.3,9.3±3.6)(3.7±2.9,2.6±2.9)分,差异有统计学意义(t/Z值分别为3.8,13.9,6.9,-2.6,P值均 < 0.05)。对TD组儿童的多重线性回归分析显示,母亲学历大学本科对SDQ-25情绪症状、大学专科对SDQ-25亲社会行为(B值分别为-2.20,2.14),父母管教态度宽松对SCARED-41广泛性焦虑、担心对SDQ-25多动(B值分别为-7.44,3.00),电子设备使用时长对SCARED-41躯体化/惊恐、学校恐怖和SDQ-25品行问题(B值分别为0.49,0.30,0.20)及运动强度小强度对CDI-10(B=-0.15)等量表得分影响有统计学意义(P值均<0.05)。 结论 TD儿童容易出现焦虑/抑郁情绪及行为问题,并与母亲学历、父母管教态度、电子设备使用时长及运动强度等因素相关。 Abstract:Objective To study the psychological and behavioral problems of children with tic disorders (TD), and to identify related influencing factors for effective medical intervention strategies. Methods From June 2020 to June 2021, 69 children with TD were randomly selected as the case group in the pediatric neurologic clinic, while the control group included 69 healthy children who were matched by gender and age. The data were obtained through general questionnaire, Screen for Child Anxiety Related Emotional Disorders-41 (SCARED-41), Strengths and Difficulties Questionnaire-25 (SDQ-25) and the Children's Depression Inventory-Short Form (CDI-10), while psychological and behavioral problems and their related risk factors were analyzed. Results The total scores of SCARED-41, SDQ-25 and its difficulties scale, and CDI-10 were (22.1±12.5, 13.3±12.3) (21.1±6.0, 15.9±3.4) (15.6±6.3, 9.3±3.6) (3.7±2.9, 2.6±2.9) in the TD and control group respectively, with significant differences (t/Z=3.8, 13.9, 6.9, -2.6, P < 0.05). According to multiple linear regression of children in the TD group, statistically significant effects of maternal bachelor degree on SDQ-25 emotional symptoms, associate degree on SDQ-25 prosocial behavior (B=-2.20, 2.14), lenient parenting attitude on SCARED-41 general anxiety, worry on SDQ-25 hyperactivity (B=-7.44, 3.00), time spent on electronic devices on SCARED-41 somatic/panic, school phobia and SDQ-25 conduct problems (B=0.49, 0.30, 0.20) and exercise intensity of small intensity on CDI-10 (B=-0.15)were observed (P < 0.05). Conclusion Children with TD are prone to emotional disturbances such as anxiety, depression and behavioral problems, all of which are related to their mothers' educational background, parents' attitude towards discipline, the duration of electronic device use and exercise intensity. -
Key words:
- Mental health /
- Behavior /
- Regression analysis /
- Child
1) 利益冲突声明 所有作者声明无利益冲突。 -
表 1 抽动障碍儿童心理行为问题影响因素多重线性回归分析(B值,n=69)
Table 1. Multiple linear regression analysis of influencing factors of psychological and behavioral problems in TD group(B, n=69)
自变量 选项 SCARED-41 SDQ-25 CDI-10 躯体化/惊恐 广泛性焦虑 分离性焦虑 社交恐怖 学校恐怖 情绪症状 品行问题 多动 同伴交往问题 亲社会行为 母亲学历 高中/同等学历 -0.18 -0.78 -0.33 -0.19 -0.82 0.43 0.25 -0.16 0.15 1.22 -0.48 大学专科 -2.36 -1.31 -1.76 -2.26 -0.76 0.45 -0.17 -0.52 -1.48 2.14* -1.60 大学本科 -2.14 -2.52 -1.33 -1.77 -0.62 -2.20* -0.10 -1.24 -0.91 1.57 -2.24 研究生 -1.36 -2.67 -2.55 -2.20 -1.76 -1.54 -0.17 -2.00 -2.05 0.43 -2.02 父母管教态度 严格 0.25 -0.60 -0.34 0.18 0.65 0.01 0.30 1.40 0.32 0.65 0.06 担心 -1.37 -1.98 -1.46 -1.39 0.36 1.20 0.40 3.00* 1.16 -0.85 0.57 宽松 -6.49 -7.44* -5.32 -5.08 -1.33 -2.38 0.56 1.95 -0.40 -2.05 0.57 运动强度 轻微运动 0.08 0.02 -1.46 0.63 0.38 -1.24 -0.25 -0.64 -0.82 1.29 -1.88 小强度运动 -2.20 -2.68 -2.22 -1.68 -0.50 -1.78 -0.96 -0.82 -0.13 1.12 -0.15* 中等强度运动 2.54 1.62 -0.41 0.11 0.21 -1.44 0.09 -1.25 -1.17 -0.10 -2.83 电子设备使用时间 0.49* 0.30 -0.90 0.19 0.30** 0.02 0.20* -0.07 0.01 -0.10 0.24 注:*P<0.05;**P<0.01。母亲学历、父母管教态度、运动强度分别以初中、合理、未参与运动为对照。 -
[1] 刘智胜, 秦炯, 王家勤, 等. 儿童抽动障碍诊断与治疗专家共识(2017实用版)[J]. 中华实用儿科临床杂志, 2017, 32(15): 1137-1140. doi: 10.3760/cma.j.issn.2095-428X.2017.15.005LIU Z S, QIN J, WANG J Q, et al. Experts consensus of treatment and diagnosis of tic disorders in children (2017 practical version)[J]. Chin J Appl Clin Pediatr, 2017, 32(15): 1137-1140. (in Chinese) doi: 10.3760/cma.j.issn.2095-428X.2017.15.005 [2] 徐通, 周翊. 儿童抽动障碍病因及发病机制[J]. 中国实用儿科杂志, 2012, 27(7): 502-505. https://www.cnki.com.cn/Article/CJFDTOTAL-ZSEK201207008.htmXU T, ZHOU Y. Etiology and pathogenesis of tic disorders in children[J]. Chin J Pract Pediatr, 2012, 27(7): 502-505. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZSEK201207008.htm [3] 李韵, 刘秀勤, 陈丽清, 等. 抽动障碍患儿焦虑情绪特点及影响因素[J]. 中华行为医学与脑科学杂志, 2018, 27(5): 416-420. doi: 10.3760/cma.j.issn.1674-6554.2018.05.007LI Y, LIU X Q, CHEN L Q, et al. Anxiety traits and influencing factors of children with tic disorders[J]. Chin J Behav Med Brain Sci, 2018, 27(5): 416-420. (in Chinese) doi: 10.3760/cma.j.issn.1674-6554.2018.05.007 [4] 刘秀勤, 李韵, 杨丽容, 等. 抽动障碍患儿一级亲属焦虑特点及对患儿焦虑情绪的影响[J]. 中华行为医学与脑科学杂志, 2018, 27(10): 892-895. doi: 10.3760/cma.j.issn.1674-6554.2018.10.006LIU X Q, LI Y, YANG L R, et al. The anxious traits of the first-degree relatives and its influence on anxiety emotion of children with tic disorders[J]. Chin J Behav Med Brain Sci, 2018, 27(10): 892-895. (in Chinese) doi: 10.3760/cma.j.issn.1674-6554.2018.10.006 [5] GIRGIS J, MARTINO D, PRINGSHEIM T. Influence of sex on tic severity and psychiatric comorbidity profile in patients with pediatric tic disorder[J]. Dev Med Child Neurol, 2022, 64(4): 488-494. doi: 10.1111/dmcn.15088 [6] American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-5) [M]. 5th ed. Arlington, VA: American Psychiatric Association, 2013: 81. [7] 王凯, 苏林雁, 朱焱, 等. 儿童焦虑性情绪障碍筛查表的中国城市常模[J]. 中国临床心理学杂志, 2002, 10(4): 270-272. doi: 10.3969/j.issn.1005-3611.2002.04.009WANG K, SU L Y, ZHU Y, et al. Norms of the screen for child anxiety related emotional disorders in Chinese urban children[J]. Chin J Clin Psychol, 2002, 10(4): 270-272. (in Chinese) doi: 10.3969/j.issn.1005-3611.2002.04.009 [8] 柳之啸, 李京, 王玉, 等. 中文版儿童抑郁量表的结构验证及测量等值[J]. 中国临床心理学杂志, 2019, 27(6): 1172-1176. https://www.cnki.com.cn/Article/CJFDTOTAL-ZLCY201906020.htmLIU Z X, LI J, WANG Y, et al. Structural verification and measurement invariance of Chinese version of Children's Depression Inventory[J]. Chin J Clin Psychol, 2019, 27(6): 1172-1176. (in Chinese) https://www.cnki.com.cn/Article/CJFDTOTAL-ZLCY201906020.htm [9] PATERSON J, MEDVEDEV O N, SUMICH A, et al. Distinguishing transient versus stable aspects of depression in New Zealand Pacific Island children using Generalizability Theory[J]. J Affect Disorder, 2018, 227: 698-704. doi: 10.1016/j.jad.2017.11.075 [10] 寇建华, 杜亚松, 夏黎明. 儿童长处和困难问卷(父母版)上海常模的信度和效度[J]. 上海精神医学, 2005, 17(1): 25-28. doi: 10.3969/j.issn.1002-0829.2005.01.007KOU J H, DU Y S, XIA L M. Reliability and validity of Children Strengths and Difficulties Questionnaire in Shanghai norm[J]. Arch Psychiatry, 2005, 17(1): 25-28. (in Chinese) doi: 10.3969/j.issn.1002-0829.2005.01.007 [11] LIU Z S, CUI Y H, SUN D, et al. Current status, diagnosis, and treatment recommendation for tic disorders in China[J]. Front Psychiatry, 2020, 11: 774. [12] CONTE G, VALENTE F, FIORIELLO F, et al. Rage attacks in tourette syndrome and chronic tic disorder: a systematic review[J]. Neurosci Biobehav Rev, 2020, 119: 21-36. doi: 10.1016/j.neubiorev.2020.09.019 [13] ESSOE J K, GRADOS M A, SINGER H S, et al. Evidence-based treatment of Tourette's disorder and chronic tic disorders[J]. Expert Rev Neurother, 2019, 19(11): 1103-1115. doi: 10.1080/14737175.2019.1643236 [14] MATHEWS C A, BIMSON B, LOWE T L, et al. Association between maternal smoking and increased symptom severity in Tourette's syndrome[J]. Am J Psychiatry, 2006, 163(6): 1066-1073. doi: 10.1176/ajp.2006.163.6.1066 [15] SILVESTRI P R, CHIAROTTI F, GIUSTINI S, et al. Alexithymia and tic disorders: a study on a sample of children and their mothers[J]. Eur Child Adolesc Psychiatry, 2019, 28(4): 461-470. doi: 10.1007/s00787-018-1209-x [16] BROEREN S, NEWALL C, DODD H F, et al. Longitudinal investigation of the role of temperament and stressful life events in childhood anxiety[J]. Dev Psychopathol, 2014, 26(2): 437-449. doi: 10.1017/S0954579413000989 [17] MIRZAEI M, YASINI A S, MIRZAEI M, et al. Prevalence of depression, anxiety and stress among adult population: results of yazd health study[J]. Iran J Psychiatry, 2019, 14(2): 137-146. [18] PARKES A, SWEETING H, WIGHT D. Parenting stress and parent support among mothers with high and low education[J]. J Fam Psychol, 2015, 29(6): 907-918. doi: 10.1037/fam0000129 [19] 左本琴. 3~4岁幼儿社会性发展及其与家庭环境的关联研究[D]. 上海: 华东师范大学, 2011.ZUO B Q. The study on the development of sociality in young children aged 3-4 and the relevance with family environment[D]. Shanghai: East China Normal University, 2011. (in Chinese) [20] 中华医学会儿科学分会发育行为学组. 注意缺陷多动障碍早期识别、规范诊断和治疗的儿科专家共识[J]. 中华儿科杂志, 2020, 58(3): 188-193.Subspecialty Group of Developmental and Behavioral Pediatrics, Society of Pediatrics, CMA. Consensus on pediatric clinical practice of early identification, standardized diagnosis and treatment of attention deficit hyperactivity disorder[J]. Chin J Pediatr, 2020, 58(3): 188-193. (in Chinese) [21] DIETZ L J, WEINBERG R J, BRENT D A, et al. Family-based interpersonal psychotherapy for depressed preadolescents: examining efficacy and potential treatment mechanisms[J]. J Am Acad Child Adolesc Psychiatry, 2015, 54(3): 191-199. doi: 10.1016/j.jaac.2014.12.011 [22] GRAZIANO P A, ROS-DEMARIZE R, HARE M M. Condensing parent training: a randomized trial comparing the efficacy of a briefer, more intensive version of Parent-Child Interaction Therapy (I-PCIT)[J]. J Cons Clin Psychol, 2020, 88(7): 669-679. [23] REDMAYNE M, SMITH E, ABRAMSON M J. The relationship between adolescents' well-being and their wireless phone use: a cross-sectional study[J]. Environ Health, 2013, 12: 90. [24] KESARI K K, SIDDIQUI M H, MEENA R, et al. Cell phone radiation exposure on brain and associated biological systems[J]. Indian J Exp Biol, 2013, 51(3): 187-200. [25] OBERLE E, JI X R, KERAI S, et al. Screen time and extracurricular activities as risk and protective factors for mental health in adolescence: a population-level study[J]. Prev Med, 2020, 141: 106291. [26] FIELD T. Exercise research on children and adolescents[J]. Complement Ther Clin Pract, 2012, 18(1): 54-59. [27] BIDDLE S J, ASARE M. Physical activity and mental health in children and adolescents: a review of reviews[J]. Br J Sports Med, 2011, 45(11): 886-895. [28] ALVES J, ALVES G V. Effects of physical activity on children's growth[J]. J Pediatr, 2019, 95(Suppl 1): 72-78. [29] SERRA L, RAIMONDI S, DI DOMENICO C, et al. The beneficial effects of physical exercise on visuospatial working memory in preadolescent children[J]. AIMS Neurosci, 2021, 8(4): 496-509. [30] CHEN P, WANG D, SHEN H, et al. Physical activity and health in Chinese children and adolescents: expert consensus statement (2020)[J]. Br J Sports Med, 2020, 54(22): 1321-1331. -

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