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青少年特发性脊柱侧弯发病机制及运动干预研究进展

廖粤生 白莉莉

廖粤生, 白莉莉. 青少年特发性脊柱侧弯发病机制及运动干预研究进展[J]. 中国学校卫生, 2022, 43(9): 1436-1440. doi: 10.16835/j.cnki.1000-9817.2022.09.038
引用本文: 廖粤生, 白莉莉. 青少年特发性脊柱侧弯发病机制及运动干预研究进展[J]. 中国学校卫生, 2022, 43(9): 1436-1440. doi: 10.16835/j.cnki.1000-9817.2022.09.038
LIAO Yuesheng, BAI Lili. Research updates on the pathogenesis of adolescent idiopathic scoliosis and sports intervention[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2022, 43(9): 1436-1440. doi: 10.16835/j.cnki.1000-9817.2022.09.038
Citation: LIAO Yuesheng, BAI Lili. Research updates on the pathogenesis of adolescent idiopathic scoliosis and sports intervention[J]. CHINESE JOURNAL OF SCHOOL HEALTH, 2022, 43(9): 1436-1440. doi: 10.16835/j.cnki.1000-9817.2022.09.038

青少年特发性脊柱侧弯发病机制及运动干预研究进展

doi: 10.16835/j.cnki.1000-9817.2022.09.038
基金项目: 

国家社会科学基金重大项目 19ZDA353

国家社会科学基金青年项目 20CTY004

详细信息
    作者简介:

    廖粤生(1997-),男,江西赣州人,在读硕士,主要研究方向为运动与健康促进

    通讯作者:

    白莉莉, E-mail: blx0305@163.com

  • 利益冲突声明  所有作者声明无利益冲突。
  • 中图分类号: R726.8 R179 G806

Research updates on the pathogenesis of adolescent idiopathic scoliosis and sports intervention

  • 摘要: 青少年特发性脊柱侧弯(adolescent idiopathic scoliosis,AIS)指一种包括冠状面上的侧弯、矢状面上的失平衡和椎体在横轴位上旋转在内的三维畸形,无任何先天性脊柱异常或合并有神经肌肉和骨骼等疾病,是临床最常见的结构性脊柱侧弯。中国AIS的患病率呈不断上升趋势,成为威胁青少年健康的重要卫生问题。运动疗法对于预防与治疗AIS具有积极的效应,但其潜在机制尚不十分明确。研究综述了近年来关于AIS发生与发展的病理机制及运动疗法对AIS的干预作用及相关机制,以期为治疗AIS提供参考。
    1)  利益冲突声明  所有作者声明无利益冲突。
  • [1] PÉREZ-MACHADO G, BERENGUER-PASCUAL E, BOVEA-MARCO M, et al. From genetics to epigenetics to unravel the etiology of adolescent idiopathic scoliosis[J]. Bone, 2020, 140(17): 5563-5570.
    [2] DE KLEUVER M, FARAJ S S A, HAANSTRA T M, et al. The scoliosis research society adult spinal deformity standard outcome set[J]. Spine Deform, 2021, 9(5): 1211-1221. doi: 10.1007/s43390-021-00334-2
    [3] 施冬冬, 陈前芬. 青少年特发性脊柱侧凸病因学的研究进展[J]. 中国学校卫生, 2021, 42(2): 316-320. doi: 10.16835/j.cnki.1000-9817.2021.02.038

    SHI D D, CHEN Q F. Current insights into the aetiology of adolescent idiopathic scoliosis[J]. Chin J Sch Health, 2021, 42(2): 316-320. doi: 10.16835/j.cnki.1000-9817.2021.02.038
    [4] SIMONY A, CARREON L Y, JMARK K H, et al. Concordance rates of adolescent idiopathic scoliosis in a Danish twin population[J]. Spine, 2020, 41(19): 1503-1507.
    [5] SHARMA S, LONDONO D, ECKALBAR W L, et al. A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females[J]. Nat Commun, 2021, 6(3): 6452-6456.
    [6] TAKAHASHI Y, KOU I, TAKAHASHI A, et al. A genome-wide association study identifies common variants near LBX1 associated with adolescent idiopathic scoliosis[J]. Nat Genet, 2020, 43(12): 1237-1240.
    [7] AL-KATEB H, KHANNA G, FILGES I, et al. Scoliosis and vertebral anomalies: additional abnormal phenotypes associated with chromosome 16p11.2 rearrangement[J]. Am J Med Genet A, 2019, 164A(5): 1118-1126.
    [8] YANG K G, LEE W Y W, HUNG A L H, et al. Decreased cortical bone density and mechanical strength with associated elevated bone turnover markers at peri-pubertal peak height velocity: a cross-sectional and longitudinal cohort study of 396 girls with adolescent idiopathic scoliosis[J]. Osteoporos Int, 2021, 10(1): 56-60.
    [9] WANG W J, SUN C, LIU Z, et al. Transcription factor Runx2 in the low bone mineral density of girls with adolescent idiopathic scoliosis[J]. Orthop Surg, 2014, 6(1): 8-14. doi: 10.1111/os.12087
    [10] LAM T P, YANG G, PANG H, et al. A six years longitudinal cohort study on the changes in bone density and bone quality up to peak bone mass in adolescent idiopathic scoliosis (AIS) with and without 2 years of Calcium and Vit-D supplementation[J]. Stud Health Technol Inform, 2021, 280(8): 31-34.
    [11] MURAKAMI N, OBATA K, ABE Y, et al. Scoliosis in Prader-Willi syndrome: effect of growth hormone therapy and value of paravertebral muscle volume by CT in predicting scoliosis progression[J]. Am J Med Genet A, 2018, 158A(7): 1628-1632.
    [12] GROOTJEN L N, RUTGES J P H J, DAMEN L, et al. Effects of 8 years of growth hormone treatment on scoliosis in children with Prader-Willi syndrome[J]. Eur J Endocrinol, 2021, 185(1): 47-55. doi: 10.1530/EJE-21-0211
    [13] YUN Y H, KWON S S, KOH Y, et al. Influence of growth hormone treatment on radiographic indices of the spine: propensity-matched analysis[J]. J Orthop Surg Res, 2017, 12(1): 130-135. doi: 10.1186/s13018-017-0630-z
    [14] LIU H, LIU Z, MAN C W, et al. The effect of exogenous melatonin on reducing scoliotic curvature and improving bone quality in melatonin-deficient C57BL/6J mice[J]. Sci Rep, 2019, 9(1): 6202-6208. doi: 10.1038/s41598-019-42467-5
    [15] GARGANO G, OLIVA F, MIGLIORINI F, et al. Melatonin and adolescent idiopathic scoliosis: the present evidence[J]. Surgeon, 2021, 9(21): 134-137.
    [16] GIRARDO M, BETTINI N, DEMA E, et al. The role of melatonin in the pathogenesis of adolescent idiopathic scoliosis (AIS)[J]. Eur Spine J, 2019, 28(1): S68-S74.
    [17] WU T, SUN X, ZHU Z, et al. Role of enhanced central leptin activity in a scoliosis model created in bipedal amputated mice[J]. Spine, 2021, 46(19): E1041-E1045.
    [18] LIU Z, TAM E M, SUN G Q, et al. Abnormal leptin bioavailability in adolescent idiopathic scoliosis: an important new finding[J]. Spine, 2019, 44(7): 599-604.
    [19] QIU Y, SUN X, QIU X, et al. Decreased circulating leptin level and its association with body and bone mass in girls with adolescent idiopathic scoliosis[J]. Spine, 2017, 42(24): 2703-2710.
    [20] INOUE M, MINAMI S, NAKATA Y, et al. Association between estrogen receptor gene polymorphisms and curve severity of idiopathic scoliosis[J]. Spine, 2020, 45(21): 2357-2362.
    [21] WU J, QIU Y, ZHANG L, et al. Association of estrogen receptor gene polymorphisms with susceptibility to adolescent idiopathic scoliosis[J]. Spine, 2019, 44(10): 1131-1136.
    [22] CHENG J C, GUO X, SHER A H, et al. Correlation between curve severity, somatosensory evoked potentials, and magnetic resonance imaging in adolescent idiopathic scoliosis[J]. Spine, 2021, 46(16): 1679-1684.
    [23] VILLEMURE I, AUBIN C E, DANSEREAU J, et al. Biomechanical simulations of the spine deformation process in adolescent idiopathic scoliosis from different pathogenesis hypotheses[J]. Eur Spine J, 2020, 29(1): 83-90.
    [24] QIAO J, XU L, LIU Z, et al. Surgical treatment of scoliosis in Marfan syndrome: outcomes and complications[J]. Eur Spine J, 2016, 25(10): 3288-3293. doi: 10.1007/s00586-016-4579-0
    [25] PASTORELLI F, DI SILVESTRE M, VOMMARO F, et al. Intraoperative monitoring of somatosensory (SSEPs) and transcranial electric motor-evoked potentials (tce-MEPs) during surgical correction of neuromuscular scoliosis in patients with central or peripheral nervous system diseases[J]. Eur Spine J, 2020, 29(7): 931-936.
    [26] CHEON M, PARK J, LEE Y, et al. Effect of chiropractic and lumbar exercise program on lumbar muscle strength and Cobb's angle in patients with scoliosis for u-Healthcare[J]. EURASIP J Wirel Commun Netw, 2013, 13(1): 45-51.
    [27] KIM G, HWANGBO P N. Effects of Schroth and Pilates exercises on the Cobb angle and weight distribution of patients with scoliosis[J]. J Phys Ther Sci, 2016, 28(3): 1012-1015. doi: 10.1589/jpts.28.1012
    [28] PARK Y H, PARK Y S, LEE Y T, et al. The effect of a core exercise program on Cobb angle and back muscle activity in male students with functional scoliosis: a prospective, randomized, parallel-group, comparative study[J]. J Int Med Res, 2016, 44(3): 728-734. doi: 10.1177/0300060516639750
    [29] GVR G, AYHAN C, YAKUT Y. The effectiveness of core stabilization exercise in adolescent idiopathic scoliosis: a randomized controlled trial[J]. Prosthet Orthot Int, 2017, 41(3): 303-310. doi: 10.1177/0309364616664151
    [30] KWAN K Y H, CHENG A C S, KOH H Y, et al. Effectiveness of Schroth exercises during bracing in adolescent idiopathic scoliosis: results from a preliminary study-SOSORT Award 2017 Winner[J]. Scoliosis Spinal Disord, 2017, 10(2): 28-32.
    [31] KO K J, KANG S J. Effects of 12-week core stabilization exercise on the Cobb angle and lumbar muscle strength of adolescents with idiopathic scoliosis[J]. J Exerc Rehabil, 2017, 13(2): 244-249. doi: 10.12965/jer.1734952.476
    [32] RUF M, WIEDENHÖFER B, PITZEN T. Neuromuscular scoliosis in patients with central nervous system pathologies[J]. Orthopade, 2021, 50(8): 643-649. doi: 10.1007/s00132-021-04132-6
    [33] ISHIHARA C, SHIRAISHI Y. The seas approach reduced Cobb angle, and the thera-band exercise improved scapula winging in a double major curve type of Adolescent Idiopathic Scoliosis (AIS)-a case report[J]. Biol Cen, 2020, 9(1): 60-65.
    [34] MELO R S, LEMOS A, PAIVA G S, et al. Vestibular rehabilitation exercises programs to improve the postural control, balance and gait of children with sensorineural hearing loss: a systematic review[J]. Int J Pediatr Otorhinolaryngol, 2019, 127(1): 1096-1099.
    [35] YAGCI G, YAKUT Y. Response to letter to editor regarding "Core stabilization exercises versus scoliosis-specific exercises in moderate idiopathic scoliosis treatment" by Yagci and Yakut (2019)[J]. Prosthet Orthot Int, 2020, 44(4): 265-266. doi: 10.1177/0309364620927613
    [36] KURU T, YELDAN Í, DERELI E E, et al. The efficacy of three-dimensional Schroth exercises in adolescent idiopathic scoliosis: a randomised controlled clinical trial[J]. Clin Rehabil, 2016, 30(2): 181-190. doi: 10.1177/0269215515575745
    [37] YANG J M, LEE J H, LEE D H. Effects of consecutive application of stretching, Schroth, and strengthening exercises on Cobb's angle and the rib hump in an adult with idiopathic scoliosis[J]. J Phys Ther Sci, 2020, 27(8): 2667-2669.
    [38] GAO A, LI J Y, SHAO R, et al. Schroth exercises improve health-related quality of life and radiographic parameters in adolescent idiopathic scoliosis patients[J]. Chin Med J, 2021, 134(21): 2589-2596. doi: 10.1097/CM9.0000000000001799
    [39] TALEGHANI E, SINGH A, HACHEM B, et al. Finite element assessment of a disc-replacement implant for treating scoliotic deformity[J]. Clin Biomech(Bristol, Avon), 2021, 84: 105326. doi: 10.1016/j.clinbiomech.2021.105326
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出版历程
  • 收稿日期:  2022-01-14
  • 修回日期:  2022-02-11
  • 网络出版日期:  2022-09-23
  • 刊出日期:  2022-09-25

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