银川市青少年体脂肪分布与骨矿物质含量的关系

周金玉; 白玲; 佟玲玲; 丁文清

doi:10.16835/j.cnki.1000-9817.2022.09.023

银川市青少年体脂肪分布与骨矿物质含量的关系

doi: 10.16835/j.cnki.1000-9817.2022.09.023

宁夏医科大学公共卫生与管理学院/宁夏环境因素与慢性病控制重点实验室，银川 750004

基金项目:

国家自然科学基金项目 82160641

详细信息

作者简介:
周金玉(1997-)，女，宁夏吴忠人，在读硕士，主要研究方向为儿童青少年慢性流行病学

通讯作者:
丁文清，E-mail：dwqdz@163.com

利益冲突声明 所有作者声明无利益冲突。
中图分类号: R446 G478 R179
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出版历程
- 收稿日期: 2022-02-18
- 修回日期: 2022-04-29
- 网络出版日期: 2022-09-23
- 刊出日期: 2022-09-25

Relationship between body fat distribution and bone mineral content of adolescents in Yinchuan

School of Public Health and Management/Key Laboratory of Environmental Factors and Chronic Disease Control, Ningxia Medical University, Yinchuan (750004), China

摘要

摘要: 目的分析青少年体脂肪分布与骨矿物质含量(bone mineral content, BMC)的关系以及在不同性别间的差异, 为青少年骨代谢疾病的防治提供科学依据。方法以整群随机抽样的方法从银川市选取1 575名12~18岁青少年作为研究对象, 进行问卷调查、体格检查、体成分及骨矿物质含量测定, 采用多元线性回归分析探讨校正混杂因素后体脂肪分布与BMC水平的关系。结果除四肢-全身脂肪比(LTFR)外, 男生全身脂肪含量(fat mass, FM)、四肢脂肪含量(appendicular fat mass, AFM)、躯干脂肪含量(trunk fat mass, TFM)、躯干-全身脂肪比(TrTFR)、躯干-四肢脂肪比(TrLFR)均低于女生(t值分别为-13.52, -15.18, -12.47, -12.25, -7.96, P值均 < 0.05);调整年龄、性别和体重后, FM、AFM、TFM、LTFR、TrTFR均与BMC水平呈负相关(P值均 < 0.05), 其中TFM每增加1个标准差, BMC水平下降0.53个标准差(95%CI=-0.57~-0.49, P < 0.01)。在男生中, LTFR与BMC水平呈负相关(B=-0.07)(P < 0.01), 而在女生中无相关性(B=0.01, P=0.74);在女生中, TrLFR与BMC水平呈负相关(B=-0.06)(P=0.03), 而在男生的相关性无统计学意义(B=-0.01, P=0.55)。结论青少年体脂肪分布存在性别差异, 且在这一时期, 体脂肪分布与骨矿物质含量显著相关。应多关注青少年体脂肪的分布, 为提早预防青少年骨代谢疾病提供科学依据。
- 脂肪组织 /
- 骨和骨组织 /
- 矿物质 /
- 生长和发育 /
- 青少年
Abstract: Objective To analyze the relationship between body fat distribution and bone mineral content (BMC) in adolescents and gender differences among Chinese adolescents, and to provide a scientific basis for the prevention and treatment of bone metabolic diseases. Methods A total of 1 575 adolescents aged 12-18 years old were selected from Yinchuan by cluster random sampling.Body composition and bone mineral content were measured by bioelectrical impedance analysis (BIA).Multiple linear regression analysis was used to explore the relationship between body fat distribution and BMC after adjusting for confounding factors. Results Except for LTFR, the levels of FM, AFM, TFM, TrTFR and TrLFR in boys were lower than those in girls (t=-13.52, -15.18, -12.47, -12.25, -7.96, P < 0.05);After adjusting for age, sex and weight, FM, AFM, TFM, TrTFR and TrLFR were all negatively correlated with BMC level (P < 0.05).For each increase of 1 standard deviation in TFM, BMC level decreased by 0.53 standard deviation (95%CI=-0.57--0.49, P < 0.01].LTFR had a linear negative correlation with BMC level in boys (B=0.07, P < 0.01), no similar correlation was found in girls (B=0.01, P=0.74).There was a linear negative correlation between TrLFR and BMC level in girls (B=-0.06, P=0.03), but the correlation was of no significance in boys (B=-0.01, P=0.55). Conclusion Sex difference in body fat distribution in Chinese adolescents is observed.Body fat distribution is closely related to bone minerals content in adolescents.
- Adipose tissue /
- Bone and bones /
- Minerals /
- Growth and development /
- Adolescent
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表 1 不同性别学生体格检查指标、体脂肪含量与骨矿物质含量比较(x ±s)

Table 1. Comparison of physical examination, body fat content and bone mineral content among students of different genders(x ±s)

性别	人数	年龄/岁	身高/cm	体重/kg	BMI/(kg·m^-2)	BMC/g	FM/kg^*
男	995	15.30±1.59	171.72±7.50	60.44±13.02	20.39±3.67	2 812.80±479.07	7.80(5.78, 12.90)
女	580	14.97±1.87	162.43±5.71	54.29±9.84	20.54±3.30	2 346.60±300.56	14.40(11.30, 18.50)
合计	1 575	15.18±1.71	168.32±8.22	58.18±12.31	20.45±3.54	2 642.01±478.45	10.80(6.70, 16.30)
t/Z值		3.65	25.76	9.84	0.75	21.10	17.13
P值		< 0.01	< 0.01	< 0.01	0.45	< 0.01	< 0.01

性别	人数	AFM/kg^*	TFM/kg^*	LTFR/%	TrTFR/%	TrLFR/%
男	995	3.70(2.90, 5.70)	3.20(1.90, 6.13)	48.52±5.58	39.55±10.08	84.51±27.49
女	580	6.90(5.45, 8.70)	6.70(5.00, 8.95)	48.13±2.85	44.99±4.50	94.24±13.56
合计	1 575	5.00(3.30, 7.50)	4.80(2.50, 7.80)	48.38±4.77	41.54±8.87	88.08±23.84
t/Z值		19.04	15.89	1.58	-12.25	-7.96
P值		< 0.01	< 0.01	0.12	< 0.01	< 0.01
注：*为M(P₂₅，P₇₅)。

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表 2 青少年体脂肪分布与BMC的偏相关分析(r值)

Table 2. Partial correlation between body fat distribution and BMC among adolescent(r)

变量	男(n=995)	女(n=580)	合计(n=1 575)
FM	-0.88^**	-0.85^**	-0.91^**
AFM	-0.86^**	-0.80^**	-0.90^**
TFM	-0.87^**	-0.84^**	-0.90^**
LTFR	-0.06	0.05	0.08^**
TrTFR	-0.19^**	-0.20^**	-0.41^**
TrLFR	-0.12^**	-0.15^**	-0.33^**
注：**P < 0.01。

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表 3 青少年体脂肪分布指标与BMC的多元线性回归分析

Table 3. Multivariate linear regression analysis of body fat distribution and BMC among adolescent

变量	男(n=995)		女(n=580)		合计(n=1 575)
变量	B值(B值95%CI)	P值	B值(B值95%CI)	P值	B值(B值95%CI)	P值
FM	-0.61(-0.65~-0.57)	< 0.01	-0.66(-0.75~-0.58)	< 0.01	-0.52(-0.56~-0.48)	< 0.01
AFM	-0.56(-0.60~-0.53)	< 0.01	-0.60(-0.68~-0.52)	< 0.01	-0.48(-0.52~-0.45)	< 0.01
TFM	-0.63(-0.67~-0.58)	< 0.01	-0.66(-0.74~-0.57)	< 0.01	-0.53(-0.57~-0.49)	< 0.01
LTFR	-0.07(-0.11~-0.04)	< 0.01	0.01(-0.04~0.05)	0.74	-0.03(-0.06~-0.01)	0.03
TrTFR	-0.05(-0.09~-0.01)	0.01	-0.09(-0.15~-0.04)	< 0.01	-0.06(-0.09~-0.03)	< 0.01
TrLFR	-0.01(-0.05~0.03)	0.55	-0.06(-0.11~-0.01)	0.03	-0.03(-0.06~0.01)	0.08
注：FM、AFM、TFM、LTFR、TrTFR、TrLFR、BMC均计算经性别-年龄别的标准化转换后的Z评分。

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