童年期不良经历对端粒形态影响的研究进展

肖婉; 万宇辉

doi:10.16835/j.cnki.1000-9817.2022.08.034

童年期不良经历对端粒形态影响的研究进展

doi: 10.16835/j.cnki.1000-9817.2022.08.034

肖婉,
万宇辉^,

安徽医科大学公共卫生学院儿少卫生与妇幼保健学系/出生人口健康教育部重点实验室/ 人口健康与优生安徽省重点实验室，合肥 230032

基金项目:

安徽省自然科学基金优青项目 2208085Y23

国家自然科学基金项目 82073576

国家自然科学基金项目 81773453

详细信息

作者简介:
肖婉(1998-)，女，安徽宁国人，在读硕士，主要研究方向为儿童青少年心理行为问题

通讯作者:
万宇辉，E-mail: wyhayd@163.com

利益冲突声明 所有作者声明无利益冲突。
中图分类号: B844.2 R179
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- 文章访问数: 441
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- PDF下载量: 40
- 被引次数: 0
出版历程
- 收稿日期: 2022-05-05
- 修回日期: 2022-06-13
- 网络出版日期: 2022-08-24
- 刊出日期: 2022-08-25

Research update on the effect of adverse childhood experience on telomere morphology

XIAO Wan,
WAN Yuhui^,

Department of Maternal, Child & Adolescent Health, School of Public Health/MOE Key Laboratory of Population Health across Life Cycle/Anhui Provincial Key Laboratory of Population Health & Aristogenics, Anhui Medical University, Hefei(230032), China

摘要

摘要: 童年期不良经历不仅损害个体躯体和心理健康，还可能对后代身心健康产生不良影响，越来越多的研究开始关注其中涉及的生物学机制，特别是端粒在关联中的作用已成为近年来研究的热点。研究从童年期不良经历与不同生命阶段端粒形态的改变以及端粒在童年期不良经历与健康关联中的作用进行综述，旨在深入认识童年期不良经历健康危害效应的潜在机制。
- 生活变动事件 /
- 端粒 /
- 儿童 /
- 青少年 /
- 生命周期时期 /
- 精神卫生
Abstract: Adverse childhood experiences (ACEs) not only affect individual's physical and mental health but also have adverse intergenerational effects. A growing body of researches focused on biological mechanism of ACEs, among which the emerging role of telomere has gained much attention. This article reviews the association between ACEs and telomere morphology during different developmental stages and the role of telomere in adverse health effects of ACEs. It aims to summarize possible mechanisms underlying negative effects of ACEs.
- Life change events /
- Telomere /
- Child /
- Adolescent /
- Life cycle stages /
- Mental health
注释:

1) 利益冲突声明 所有作者声明无利益冲突。

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