关注童年期不良经历代际效应 拓宽儿童身心健康研究视野

万宇辉; 陶芳标

doi:10.16835/j.cnki.1000-9817.2022.08.001

关注童年期不良经历代际效应拓宽儿童身心健康研究视野

doi: 10.16835/j.cnki.1000-9817.2022.08.001

万宇辉,
陶芳标^,

安徽医科大学公共卫生学院儿少卫生与妇幼保健学系/出生人口健康教育部重点实验室/人口健康与优生安徽省重点实验室，合肥 230032

基金项目:

安徽省自然科学基金优青项目 2208085Y23

国家自然科学基金项目 82073576

国家自然科学基金项目 81773453

详细信息

作者简介:
万宇辉(1983-)，男，安徽凤台人，博士，教授，主要研究方向为青少年心理行为问题

通讯作者:
陶芳标，E-mail：fbtao@126.com

利益冲突声明 所有作者声明无利益冲突。
中图分类号: B844.1 G78 R179
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- 文章访问数: 562
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- 被引次数: 0
出版历程
- 收稿日期: 2022-05-05
- 修回日期: 2022-06-24
- 网络出版日期: 2022-08-24
- 刊出日期: 2022-08-25

Concern for the intergenerational effects of adverse childhood experiences: promote a better understanding of children's health

WAN Yuhui,
TAO Fangbiao^,

Department of Maternal, Child & Adolescent Health, School of Public Health/MOE Key Laboratory of Population Health across Life Cycle/Anhui Provincial Key Laboratory of Population Health & Aristogenics, Anhui Medical University, Hefei(230032), China

摘要

摘要: 在充分评估童年期不良经历(adverse childhood experiences, ACEs)影响个体身心健康的基础上，父母ACEs对子代健康的作用成为当下关注的热点。基于ACEs代际健康效应的视角，重点梳理父母ACEs与儿童身心健康的关联以及潜在社会心理学和生物学机制，并提出若干研究方向，鼓励开展早期干预以打破虐待经历和健康问题的代际循环。
- 生活变动事件 /
- 代际关系 /
- 健康促进 /
- 儿童
Abstract: The impact of parental adverse childhood experiences on offspring health has become a heated issue after evaluating the role of adverse childhood experiences (ACEs) in individual's physical and mental health. The current study reviews the impact of parental ACEs on children's health from the perspective of intergenerational effects, and explores their potential psychosocial and biological mechanisms. Future research topics are proposed and early interventions are encouraged to interrupt the intergenerational cycle of victimization and health problems.
- Life change events /
- Intergenerational relations; Health promotion; Child /
- Health promotion; Child /
- Child
注释:

1) 利益冲突声明 所有作者声明无利益冲突。

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参考文献(49)

[1]	Centers for Disease Control and Prevention. BRFSS adverse childhood experience (ACE) Module[EB/OL]. (2020-02-23)[2022-03-23]. https://www.cdc.gov/violence prevention/child abuse and neglect/ace study/ace-brfss.html.
[2]	FLORES-TORRES M H, COMERFORD E, SIGNORELLO L, et al. Impact of adverse childhood experiences on cardiovascular disease risk factors in adulthood among Mexican women[J]. Child Abuse Negl, 2020, 99: 104175. doi: 10.1016/j.chiabu.2019.104175
[3]	MCCURLEY J L, GUTIERREZ A P, BRAVIN J I, et al. Association of social adversity with comorbid diabetes and depression symptoms in the Hispanic community health study/study of Latinos sociocultural ancillary study: a syndemic framework[J]. Ann Behav Med, 2019, 53(11): 975-987. doi: 10.1093/abm/kaz009
[4]	KIM Y, KIM K, CHARTIER K G, et al. Adverse childhood experience patterns, major depressive disorder, and substance use disorder in older adults[J]. Aging Ment Health, 2021, 25(3): 484-491. doi: 10.1080/13607863.2019.1693974
[5]	RACINE N, PLAMONDON A, MADIGAN S, et al. Maternal adverse childhood experiences and infant development[J]. Pediatrics, 2018, 141(4): e20172495. doi: 10.1542/peds.2017-2495
[6]	FOLGER A T, EISMANN E A, STEPHENSON N B, et al. Parental adverse childhood experiences and offspring development at 2 years of age[J]. Pediatrics, 2018, 141(4): e20172826. doi: 10.1542/peds.2017-2826
[7]	SUN J, PATEL F, ROSE-JACOBS R, et al. Mothers' adverse childhood experiences and their young children's development[J]. Am J Prev Med, 2017, 53(6): 882-891. doi: 10.1016/j.amepre.2017.07.015
[8]	LÊ-SCHERBAN F, WANG X, BOYLE-STEED K H, et al. Intergenerational associations of parent adverse childhood experiences and child health outcomes[J]. Pediatrics, 2018, 141(6): e20174274. doi: 10.1542/peds.2017-4274
[9]	WANG X, YIN G, GUO F, et al. Associations of maternal adverse childhood experiences with behavioral problems in preschool children[J]. J Interpers Viol, 2021. DOI:10.1177/08862605211 050093.
[10]	EBONI H, ELIZABETH C, JANICE P, et al. Exploring the association between a parent's exposure to adverse childhood experiences (ACEs) and outcomes of depression and anxiety among their children[J]. Child Youth Serv Rev, 2020, 113: 105013. doi: 10.1016/j.childyouth.2020.105013
[11]	FREDLAND N, MCFARLANE J, SYMES L, et al. Exploring the association of maternal adverse childhood experiences with maternal health and child behavior following intimate partner violence[J]. J Womens Health(Larchmt), 2018, 27(1): 64-71. doi: 10.1089/jwh.2016.5969
[12]	COOKE J E, RACINE N, PADOR P, et al. Maternal adverse childhood experiences and child behavior problems: a systematic review[J]. Pediatrics, 2021, 148(3): e2020044131. doi: 10.1542/peds.2020-044131
[13]	GREENE C A, HAISLEY L, WALLACE C, et al. Intergenerational effects of childhood maltreatment: a systematic review of the parenting practices of adult survivors of childhood abuse, neglect, and violence[J]. Clin Psychol Rev, 2020, 80: 101891. doi: 10.1016/j.cpr.2020.101891
[14]	KERR D C R, GINI G, OWEN L D, et al. Peer teasing experiences of fathers and their children: intergenerational associations and transmission mechanisms[J]. Child Abuse Negl, 2018, 86: 33-44. doi: 10.1016/j.chiabu.2018.09.003
[15]	DOIS, FUJIWARA T, ISUMI A. Association between maternal adverse childhood experiences and mental health problems in offspring: an intergenerational study[J]. Dev Psychopathol, 2021, 33(3): 1041-1058. doi: 10.1017/S0954579420000334
[16]	CHANG Y T, FENG J Y, CHANG H Y, et al. The impacts of maternal childhood adversity, stress, and mental health on child development at 6 months in Taiwan: a follow-up study[J]. Dev Psychopathol, 2021, 33(3): 970-979. doi: 10.1017/S0954579420000267
[17]	MCDONALD S W, MADIGAN S, RACINE N, et al. Maternal adverse childhood experiences, mental health, and child behaviour at age 3: the all our families community cohort study[J]. Prev Med, 2019, 118: 286-294. doi: 10.1016/j.ypmed.2018.11.013
[18]	GIALLO R, GARTLAND D, SEYMOUR M, et al. Maternal childhood abuse and children's emotional-behavioral difficulties: intergenerational transmission via birth outcomes and psychosocial health[J]. J Fam Psychol, 2020, 34(1): 112-121. doi: 10.1037/fam0000623
[19]	NEGRIFF S, PALMER MOLINA A, HACKMAN D A. Parental exposure to childhood maltreatment and offspring's mental health: investigating pathways through parental adversity and offspring exposure to maltreatment[J]. Child Maltreat, 2020, 25(4): 422-432. doi: 10.1177/1077559520912342
[20]	SIERAU S, WARMINGHAM J, WHITE L O, et al. Childhood emotional and conduct problems in childhood and adolescence differentially associated with intergenerational maltreatment continuity and parental internalizing symptoms[J]. J Abn Child Psychol, 2020, 48(1): 29-42.
[21]	WARMINGHAM J M, ROGOSCH F A, CICCHETTI D. Intergenerational maltreatment and child emotion dysregulation[J]. Child Abuse Negl, 2020, 102: 104377. doi: 10.1016/j.chiabu.2020.104377
[22]	BABCOCK FENERCI R L, ALLEN B. From mother to child: maternal betrayal trauma and risk for maltreatment and psychopathology in the next generation[J]. Child Abuse Negl, 2018, 82: 1-11. doi: 10.1016/j.chiabu.2018.05.014
[23]	MADIGAN S, CYR C, EIRICH R, et al. Testing the cycle of maltreatment hypothesis: Meta-analytic evidence of the intergenerational transmission of child maltreatment[J]. Dev Psychopathol, 2019, 31(1): 23-51. doi: 10.1017/S0954579418001700
[24]	BUFFARINI R, HAMMERTON G, COLL C V N, et al. Maternal adverse childhood experiences (ACEs) and their associations with intimate partner violence and child maltreatment: results from a Brazilian birth cohort[J]. Prev Med, 2022, 155: 106928. doi: 10.1016/j.ypmed.2021.106928
[25]	YOON Y, CEDERBAUM J A, MENNEN F E, et al. Linkage between teen mother's childhood adversity and externalizing behaviors in their children at age 11: three aspects of parenting[J]. Child Abuse Negl, 2019, 88: 326-336. doi: 10.1016/j.chiabu.2018.12.005
[26]	MOISIADIS V G, MATTHEWS S G. Glucocorticoids and fetal programming part 2: mechanisms[J]. Nat Rev Endocrinol, 2014, 10(7): 403-411. doi: 10.1038/nrendo.2014.74
[27]	THOMAS-ARGYRIOU J C, LETOURNEAU N, DEWEY D, et al. The role of HPA-axis function during pregnancy in the intergenerational transmission of maternal adverse childhood experiences to child behavior problems[J]. Dev Psychopathol, 2021, 33(1): 284-300. doi: 10.1017/S0954579419001767
[28]	THOMAS J C, LETOURNEAU N, CAMPBELL T S, et al. Social buffering of the maternal and infant HPA axes: mediation and moderation in the intergenerational transmission of adverse childhood experiences[J]. Dev Psychopathol, 2018, 30(3): 921-939. doi: 10.1017/S0954579418000512
[29]	GRAHAM A M, RASMUSSEN J M, ENTRINGER S, et al. Maternal cortisol concentrations during pregnancy and sex-specific associations with neonatal amygdala connectivity and emerging internalizing behaviors[J]. Biol Psychiatry, 2019, 85(2): 172-181. doi: 10.1016/j.biopsych.2018.06.023
[30]	TYRKA A R, PRICE L H, KAO H T, et al. Childhood maltreatment and telomere shortening: preliminary support for an effect of early stress on cellular aging[J]. Biol Psychiatry, 2010, 67(6): 531-534. doi: 10.1016/j.biopsych.2009.08.014
[31]	ESTEVES K C, JONES C W, WADE M, et al. Adverse childhood experiences: implications for offspring telomere length and psychopathology[J]. Am J Psychiatry, 2020, 177(1): 47-57. doi: 10.1176/appi.ajp.2019.18030335
[32]	ETZEL L, HASTINGS W J, MATTERN B C, et al. Intergenerational transmission of childhood trauma?Testing cellular aging in mothers exposed to sexual abuse and their children[J]. Psychoneuroendocrinology, 2020, 120: 104781. doi: 10.1016/j.psyneuen.2020.104781
[33]	JONES C W, ESTEVES K C, GRAY S A O, et al. The transgenerational transmission of maternal adverse childhood experiences(ACEs): insights from placental aging and infant autonomic nervous system reactivity[J]. Psychoneuroendocrinology, 2019, 106: 20-27. doi: 10.1016/j.psyneuen.2019.03.022
[34]	CHEN X, ZENG C, GONG C, et al. Associations between early life parent-child separation and shortened telomere length and psychopathological outcomes during adolescence[J]. Psychoneuroendocrinology, 2019, 103: 195-202. doi: 10.1016/j.psyneuen.2019.01.021
[35]	ENTRINGER S, DE PUNDER K, BUSS C, et al. The fetal programming of telomere biology hypothesis: an update[J]. Philos Trans R Soc Lond B Biol Sci, 2018, 373(1741): 20170151. doi: 10.1098/rstb.2017.0151
[36]	LANG J, MCKIE J, SMITH H, et al. Adverse childhood experiences, epigenetics and telomere length variation in childhood and beyond: a systematic review of the literature[J]. Eur Child Adolesc Psychiatry, 2020, 29(10): 1329-1338. doi: 10.1007/s00787-019-01329-1
[37]	MERRILL S M, MOORE S R, GLADISH N, et al. Paternal adverse childhood experiences: associations with infant DNA methylation[J]. Dev Psychobiol, 2021, 63(6): e22174.
[38]	RAMO-FERNÁNDEZ L, BOECK C, KOENIG A M, et al. The effects of childhood maltreatment on epigenetic regulation of stress-response associated genes: an intergenerational approach[J]. Sci Rep, 2019, 9(1): 983. doi: 10.1038/s41598-018-36689-2
[39]	FELITTI V J, ANDA R F, NORDENBERG D, et al. Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study[J]. Am J Prev Med, 1998, 14(4): 245-258. doi: 10.1016/S0749-3797(98)00017-8
[40]	GABRIELLI J, JACKSON Y. Innovative methodological and statistical approaches to the study of child maltreatment: introduction[J]. Child Abuse Negl, 2019, 87: 1-4. doi: 10.1016/j.chiabu.2018.12.001
[41]	KANG N R, KWACK Y S, SONG J K, et al. The intergenerational transmission of maternal adverse childhood experiences on offspring's psychiatric disorder and the mediating role of maternal depression: results from a cross sectional study[J]. Clin Child Psychol Psychiatry, 2022, 27(3): 613-629. doi: 10.1177/13591045211056919
[42]	HETHERINGTON E, RACINE N, MADIGAN S, et al. Relative contribution of maternal adverse childhood experiences to understanding children's externalizing and internalizing behaviours at age 5: findings from the All Our Families cohort[J]. CMAJ Open, 2020, 8(2): E352-E359. doi: 10.9778/cmajo.20190149
[43]	SCHICKEDANZ A, HALFON N, SASTRY N, et al. Parents' adverse childhood experiences and their children's behavioral health problems[J]. Pediatrics, 2018, 142(2): e20180023. doi: 10.1542/peds.2018-0023
[44]	LINDSAY K L, ENTRINGER S, BUSS C, et al. Intergenerational transmission of the effects of maternal exposure to childhood maltreatment on offspring obesity risk: a fetal programming perspective[J]. Psychoneuroendocrinology, 2020, 116: 104659. doi: 10.1016/j.psyneuen.2020.104659
[45]	APPLETON A A, KILEY K, HOLDSWORTH E A, et al. Social support during pregnancy modifies the association between maternal adverse childhood experiences and infant birth size[J]. Matern Child Health J, 2019, 23(3): 408-415. doi: 10.1007/s10995-018-02706-z
[46]	YOON S, BELLAMY J L, KIM W, et al. Father involvement and behavior problems among preadolescents at risk of maltreatment[J]. J Child Fam Stud, 2018, 27(2): 494-504. doi: 10.1007/s10826-017-0890-6
[47]	PLANALP E M, BRAUNGART-RIEKER J M. Determinants of father involvement with young children: evidence from the Early Childhood Longitudinal Study-Birth Cohort[J]. J Fam Psychol, 2016, 30(1): 135-146. doi: 10.1037/fam0000156
[48]	HAYSLIP B, FRUHAUF C A, DOLBIN-MACNAB M L. Grandparents raising grandchildren: what have we learned over the past decade?[J]. Gerontologist, 2019, 59(3): e152-e163. doi: 10.1093/geront/gnx106
[49]	SPERLICH M, SENG J, ROWE H, et al. A cycles-breaking framework to disrupt intergenerational patterns of maltreatment and vulnerability during the childbearing year[J]. J Obstet Gynecol Neonatal Nurs, 2017, 46(3): 378-389. doi: 10.1016/j.jogn.2016.11.017