不同型号角膜塑形镜控制儿童低度近视效果比较

谢龙堂; 吕太亮; 吴慧; 张萌; 胡媛媛; 林潇; 张诚诚; 吴建峰; 毕宏生

doi:10.16835/j.cnki.1000-9817.2021.12.033

不同型号角膜塑形镜控制儿童低度近视效果比较

doi: 10.16835/j.cnki.1000-9817.2021.12.033

谢龙堂¹,
吕太亮²,
吴慧²,
张萌²,
胡媛媛²,
林潇²,
张诚诚²,
吴建峰^{1, 2, ,},
毕宏生^{1, 2, ,}

1.
山东中医药大学眼科与视光医学院, 济南 250014
2.
山东省中西医结合眼病防治重点实验室/山东省高校中西医结合眼病防治技术重点实验室/山东中医药大学眼科研究所/山东中医药大学附属眼科医院/山东省眼视光与青少年视力低下防控临床医学研究中心/山东省视觉智能工程技术研究中心/山东省儿童青少年健康与近视防控研究院

基金项目:

国家重点研发计划项目 2019YFC1710202

国家重点研发计划项目 2019YFC1710203

详细信息

作者简介:
谢龙堂(1995-), 男, 山东临沂人, 硕士, 主要从事白内障与屈光不正防治研究工作

通讯作者:
吴建峰, E-mail: wujianfengrun@126.com

毕宏生, E-mai: hongshengbi@126.com

利益冲突声明 所有作者声明无利益冲突
中图分类号: R778.11 R778.3
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- 被引次数: 0
出版历程
- 收稿日期: 2021-03-15
- 修回日期: 2021-05-25
- 网络出版日期: 2021-12-23
- 刊出日期: 2021-12-25

Comparison of different orthokeratology lenses in controlling the progression of low-myopia in children

1.
Medical College of Optometry and Ophthalmology, Shandong University of Traditional Chinese Medicine, Jinan (250014), China

摘要

摘要: 目的比较不同型号角膜塑形镜控制儿童低度近视的效果，为探讨保护儿童视力的有效防治措施提供参考。方法收集前往山东中医药大学附属眼科医院就诊的8~12岁初次佩戴角膜塑形镜患者的资料175例(350只眼)，回顾性分析佩戴Mouldway，Alpha，Lucid，CRT 4种不同型号角膜塑形镜1年后眼轴长度(AL)和等效球镜度(SER)变化的差异，分析眼AL变化量、SER变化量与性别、年龄的关系。结果 Mouldway组、Alpha组、Lucid组和CRT组AL变化量M(P₂₅，P₇₅)分别为0.23(0.12，0.41)、0.30(0.17，0.45)、0.35(0.16，0.41)和0.33(0.23，0.41)mm，差异无统计学意义(Z=7.70，P>0.05)；4组SER变化量M(P₂₅，P₇₅)分别为-0.31(-1.00，0.28)、-0.38(-1.22，0.13)、-0.25(-0.84，0.13)和-0.63(-1.13，0.25)D，差异无统计学意义(Z=2.15，P>0.05)。年龄与AL变化量呈负相关(r=-0.26，P < 0.05)，与SER变化量相关无统计学意义(r=0.10，P>0.05)。不同性别儿童AL变化量(Z=-2.25)和SER变化量(Z=-1.50)差异均无统计学意义(P值均>0.05)。结论不同型号角膜塑形镜在控制低度近视儿童眼轴增长和改变眼球屈光状态效果没有显著差异。
- 角膜塑形术 /
- 眼镜 /
- 近视 /
- 儿童
Abstract: Objective To compare the effect of different orthokeratology lenses in controlling the progression of low-myopia in children, and to provide a reference for exploring effective prevention measures for eyesight of children. Methods A total of 175 cases (350 eyes) aged 8-12 years old who were fitted with orthokeratology lenses were collected in this retrospective study. The differences in the changes of the axis length (AL) and the spherical equivalent refraction (SER) were analyzed after wearing different orthokeratology lenses for one year, and the relationship between the change of AL, SER and gender, age was also analyzed. Results In the Mouldway group, Alpha group, Lucid group and CRT group, the Median (P₂₅, P₇₅) of AL changes were 0.23 (0.12, 0.41), 0.30 (0.17, 0.45), 0.35 (0.16, 0.41) and 0.33 (0.23, 0.41)mm, and there were no statistical significant difference between four groups (Z=7.70, P>0.05); The Median (P₂₅, P₇₅) of SER changes were -0.31 (-1.00, 0.28), -0.38 (-1.22, 0.13), -0.25 (-0.84, 0.13) and -0.63 (-1.13, 0.25)D, and there were no statistical significant difference between four groups (Z=2.15, P>0.05). The age had negative correlation with the change of AL (r=-0.26, P < 0.05), but has nothing to do with the change of SER (r=0.10, P>0.05). There was no statistically significant difference in the change of AL (Z=2.25, P>0.05) and SER (Z=-1.50, P>0.05) among children of different genders. Conclusion Different orthokeratology lenses have no differences in controlling the growth of the AL and changing the SER.
- Orthokeratologic procedures /
- Eyeglasses /
- Myopia /
- Child
注释:

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表 1 4种角膜塑形镜参数

Table 1. Parameters of the Ortho-K lenses

名称	设计	材料	湿润角/(°)	透光率/%	折射率/%	中心厚度/mm
Mouldway	VST	Boston XO	49	87	1.42	0.24
Alpha	VST	Boston EM	35	85	1.42	0.22
Lucid	VST	Boston XO	49	87	1.42	0.23
CRT	CRT	HDS100	42	95	1.44	0.16
注：VST(vision shaping treatment，视觉塑形治疗)，CRT(corneal refractive therapy，角膜屈光疗法)。

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表 2 配戴不同型号角膜塑形镜儿童AL、SER比较[M(P₂₅，P₇₅)]

Table 2. Comparison of data for different groups of children [M(P₂₅, P₇₅)]

组别	人数	AL基线/mm	SER基线/D	AL变化量/mm	SER变化量/D
Mouldway	55	24.36(23.74，25.03)	-2.00(-2.25，-1.50)	0.23(0.12，0.41)	-0.31(-1.00，0.28)
Alpha	42	24.14(23.69，24.73)	-2.25(-2.72，-1.75)	0.30(0.17，0.45)	-0.38(-1.22，0.13)
Lucid	30	24.50(23.86，24.80)	-1.88(-2.25，-1.50)	0.35(0.16，0.41)	-0.25(-0.84，0.13)
CRT	48	24.22(23.77，24.83)	-1.94(-2.50，-1.50)	0.33(0.23，0.41)	-0.63(-1.13，0.25)
Z值		4.69	1.78	7.70	2.15
P值		0.20	0.62	0.05	0.54

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