青少年特发性脊柱侧凸病因学的研究进展

施冬冬; 陈前芬

doi:10.16835/j.cnki.1000-9817.2021.02.038

青少年特发性脊柱侧凸病因学的研究进展

doi: 10.16835/j.cnki.1000-9817.2021.02.038

广西医科大学第二附属医院，南宁 530007

基金项目:

广西自然科学基金项目 2017GXNSFAA198300

详细信息

作者简介:
施冬冬(1990-)，男，湖北孝感人，在读硕士，主要研究方向为脊柱微创、脊柱畸形矫正

中图分类号: R 179 R 682.3 G 478
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- 被引次数: 0
出版历程
- 收稿日期: 2020-07-16
- 修回日期: 2020-09-10
- 网络出版日期: 2021-04-06
- 刊出日期: 2021-02-25

Current insights into the aetiology of adolescent idiopathic scoliosis

Second Affiliated Hospital of Guangxi Medical University, Nanning (530007), China

摘要

摘要: 青少年特发性脊柱侧凸(AIS)给青少年患者的身心健康带来困扰，关于AIS的病因研究也经历了曲折的发展。这是一种多因素、多系统的疾病演变过程。轻度侧凸患者可以选择支具保守治疗并定期随访观察, 一旦侧凸进展则往往需要通过手术进行矫正治疗，随着外科椎弓根螺钉技术的发展，外科矫形取得了不错的效果，但是长期随访脊柱侧弯的其他病理改变尚不清楚。本文将从遗传、激素、神经系统、骨骼系统、生物力学等现有的AIS发病机制方面进行综述供读者借鉴。
- 脊柱侧凸 /
- 遗传 /
- 神经系统 /
- 骨骼 /
- 青少年
Abstract: Adolescent idiopathic scoliosis (AIS) is associated with multiple physical and mental health problems among adolescent patients. This is a multi-factor, multi-system process of disease evolution. Patients with mild scoliosis can choose to receive conservative treatment with braces and regular follow-up. Once scoliosis progresses, surgical correction is often required. With the development of surgical pedicle screw technology, surgical correction has achieved good results, but other negative effects of long-term follow-up of scoliosis are not clear. This paper summarizes the existing AIS pathogenesis from the aspects of heredity, hormone, nervous system, skeletal system and biomechanics.
- Scoliosis /
- Heredity /
- Nervous system /
- Skeleton /
- Adolescent

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参考文献(55)

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