摘要:
了解银川、吴忠市7~ 17 岁儿童青少年血清微量铁、锌、铜、钙、镁元素水平及其与体格发育指标的关系,为儿童青少年合理补充微量元素提供依据.方法 采用分层整群抽样方法,在银川(兴庆区、西夏区、金凤区) 和吴忠两市抽取小学6 所、初中5 所、高中2 所.根据相关纳入和排除标准,共抽取研究对象1 860 名.进行体格测定、静脉采血,采用电感耦合等离子体发射光谱仪测定离心血清中微量元素铁、锌、铜、钙、镁水平.结果 儿童青少年铁、锌、铜、钙、镁元素总体水平中位数分别为20.23,2.98,0.76, 72.57, 13.59 mg /L,四分位数间距分别为21.67,2.98,0.38, 38.42,6.89 mg /L.不同年龄组儿童青少年铁、锌、铜、镁元素水平差异均有统计学意义(Z 值分别为20.12,89.93,55.23,55.76,P 值均<0.01),不同性别之间5 种血清微量元素总体水平差异均无统计学意义(Z 值分别为- 0.16,- 0.77,- 1.88,- 0.95,- 2.06,P 值均> 0.05).铁、锌与身高、体重呈正相关,铜、镁与身高、体重呈负相关; 锌与体质量指数(BMI) 呈正相关,铜、镁与BMI 均呈负相关; 锌与年龄别身高(HAZ) 呈正相关,铜、镁与年龄别体重(WAZ) 和年龄别BMI(BAZ) 呈负相关,铁与BAZ 呈负相关(P值均<0.05).结论 微量元素铁、锌、铜、钙、镁对儿童生长发育有重要的意义.应通过学校和家长的互动,提高儿童青少年健康保健意识.
Abstract:
Objective To examine the relationship between the levels of serum trace elements, such as iron, zinc, copper, calcium, magnesium, with growth and development indicators in children and adolescents aged 7 to 17 years in Yinchuan and Wuzhong, and to provide a basis for reasonable supplementation of trace elements. Methods The stratified cluster sampling method was used to extract 6 primary schools, 5 junior middle schools and 2 senior middle schools in Yinchuan (Xingqing District, Xixia District, Jinfeng District) and Wuzhong. According to the relevant inclusion and exclusion criteria, a total of 1 860 subjects were selected. After physical examination and intravenous blood collection, the levels of trace elements such as iron, zinc, copper, calcium and magnesium in the centrifuged serum were determined by inductively coupled plasma optical emission spectrometry. Results The median level of iron was 20.23 mg /L, the interquartile range was 21.67 mg /L, the median level of zinc was 2.98 mg /L, and the interquartile range was 2.98 mg /L. The median level of copper was 0.76 mg /L, the interquartile range was 0.38 mg /L, the median level of calcium was 72.57 mg /L, and the interquartile range was 38.42 mg /L. The median level of magnesium was 13.59 mg / L and the interquartile range was 6.89 mg /L. The comparison of the total levels of five serum trace elements in children and adolescents of different age groups showed that the levels of iron, zinc, copper and magnesium in the four age groups were statistically significant(Z valus were 20.12, 89.93, 55.23, 55.76, P<0.01). There was no significant in the total levels of five serum trace elements between different genders (Z values were -0.16, -0.77, -1.88, -0.95, -2.06, P>0.05). Iron, zinc, copper and magnesium were related to height and weight. Iron and zinc were positively correlated with height and weight, and copper and magnesium were negatively correlated with height and weight. Zinc was positively correlated with BMI, and copper, magnesium was negatively correlated with BMI. There was a positive correlation between zinc and HAZ. There was a negative correlation between copper, magnesium and WAZ and BAZ. Iron was negatively correlated with BAZ (P<0.05). Conclusion Trace elements such as iron, zinc, copper, calcium and magnesium are of important significance for children's growth and development. Through the interaction between schools and parents, it can improve the awareness of health care and promote children and adolescents' health.
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