Abstract: Objective To investigate the prevalence and related influencing factors of school bullying among leftover and non-leftover children in Guangzhou, aiming to provide a scientific basis to implement effective intervention measures.Methods Students from ten primary and middle schools graded 3-12 in Guangzhou selected via the method of cluster random sampling were invited to participate into a self-reported questionnaire.The questionnaire was comprised of social-demographics, personal behavior, and the situation of school bullying in the past six months.Multivariable logistic regression was used to estimate the risk factors for school bullying.Results The overall prevalence of school bullyng was 14.19%, with leftover children (23.05%) being higher than non-leftover children (13.02%).The results of multivariable logistic regression showed that ordinary or contradictory family relationship, and paternal drinking were the risk factors of school bullying among leftover children (OR = 2.447, 3.051, 1.624), while boys, primary school, ordinary or contradictory family relationship, maternal drinking, auto-smoking or drinking were the risk factors for school bullying experiences among non-leftover children (OR = 1.417, 2.442, 1.969, 1.941, 1.671).Conclusion School bullying was common among primary and middle school students in Guangzhou, and more leftover children suffer from it than nonleftover ones, and affected by various factors.Targeted intervention strategies should be implemented to prevent the occurrence of school bullying and ensure the healthy growth of children and adolescents.