Abstract: Objective To investigate the prevalence of depressive,anxiety and obsessive compulsive symptoms and to examine possible influence of psychological resilience,perfectionism and parental rearing style on these psychological symptoms among students from a key high school.Methods A total of 1 417 grade one high school students without depression,anxiety and obsessive-compulsive symptoms at baseline which was evaluated by center for epidemiological survey depression scale,self-rating anxiety scale and yale-brown obsessive-compulsive scale,respectively.Psychological resilience,perfectionism and parental rearing style were assessed at baseline and after 12 month later.Results Incidence of at least one psychological symptom was 19.6%(278/1 417).Results from cox regression indicated that lower scores of resilience scale and paternal emotional warmth in Egna Minnen Barndoms Uppfostran and higher score of negative perfectionism were risk factors for psychological symptoms occurrence among high school students.Conclusion The incidence of depressive,anxiety or obsessive-compulsive symptoms is almost one-fifth among high school students,calling for strategies to strengthen students' psychological resilience and reduce their negative perfectionism.